4 completed, 3 terminated, 1 active not recruiting. 8 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 4, Terminated 3, Active not recruiting 1 |
| Phase 2 | 2 | Terminated 2 |
Follow Heart Block: new trials by email Literature Review of Heart Block trials Research Report on Heart Block
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Specialized Pacing for Patients With Congenital Heart Disease Closed loop stimulation, Standard rate response - Congenital Heart Disease, Bradycardia Sinus | Phase 2 / Phase 3 | Terminated | University of California, Los Angeles | 4 | 2021-05-09 | 2023-01-20 |
| Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ) Dexamethasone, IVIG - AVB - Atrioventricular Block, Fetal AVB | Phase 3 | Active not recruiting | NYU Langone Health | 1300 | 2020-08-01 | 2026-08-25 |
| Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections. polymixin/bacitracin, cephalexin, or levofloxacin, or clindamycin, Saline - Sick Sinus Syndrome, Complete Heart Block | Phase 3 | Completed | Vanderbilt University Medical Center | 1010 | 2016-04-01 | 2022-05-09 |
| MADIT ASIA Cardiac Resynchronization Trial Two-lead CRT-P - Congestive Heart Failure, Left Bundle Branch Block | Phase 3 | Terminated | Boston Scientific Corporation | 1 | 2014-02-01 | 2014-04-30 |
| Increasing Atrial Base Rate Pacing to Reduce Atrial Fibrillation HBR, DD - Sick Sinus Syndrome, Paroxysmal Atrial Fibrillation | Phase 3 | Completed | Urmia University of Medical Sciences | 200 | 2014-01-01 | 2015-10-21 |
| Comparison of SEPTal and Apical Pacing Sites in PerManent Right Ventricular Pacing RV lead - Atrioventricular Block | Phase 3 | Completed | Rennes University Hospital | 141 | 2010-04-01 | 2023-05-24 |
| The Danish Multicenter Randomised Study on AAI Versus DDD Pacing in Sick Sinus Syndrome AAIR/DDDR pacemaker - Sick Sinus Syndrome | Phase 2 / Phase 3 | Terminated | The DANPACE Investigator Group | 1415 | 1999-03-01 | 2009-02-24 |
| Mode Selection Trial in Sinus Node Dysfunction (MOST) pacemaker, artificial - Arrhythmia, Cardiovascular Diseases | Phase 3 | Completed | Mt. Sinai Medical Center, Miami | 1995-06-01 | 2016-02-23 |
Sick Sinus Syndrome (5) · Atrioventricular Block (2) · Arrhythmias, Cardiac (1) · Atrial Fibrillation (1) · Bundle-Branch Block (1) · Cardiovascular Diseases (1) · Heart Defects, Congenital (1) · Heart Diseases (1) · Heart Failure (1) · Heart Failure, Systolic (1) · Stroke (1) · Syncope (1) · Vascular Diseases (1)
Cardiac Conduction System Disease (8) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Arrhythmias, Cardiac (7) · Cardiovascular Diseases (7) · Heart Diseases (7) · Arrhythmia, Sinus (5) · Nervous System Diseases (2) · Brain Diseases (1) · Cardiovascular Abnormalities (1) · Central Nervous System Diseases (1) · Cerebrovascular Disorders (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1)
Bacitracin (1) · Cephalexin (1) · Clindamycin (1) · Dexamethasone (1) · Immunoglobulins, Intravenous (1) · Levofloxacin (1) · Pacemaker, Artificial (1) · Sodium Chloride (1)
Boston Scientific Corporation (1) · Mt. Sinai Medical Center, Miami (1) · NYU Langone Health (1) · Rennes University Hospital (1) · The DANPACE Investigator Group (1) · University of California, Los Angeles (1) · Urmia University of Medical Sciences (1) · Vanderbilt University Medical Center (1)
United States (3) · Canada (1) · China (1) · Denmark (1) · France (1) · India (1) · Iran (1) · Japan (1) · Malaysia (1) · Singapore (1) · South Korea (1) · Taiwan (1) · Thailand (1)
Arthur J. Moss, M.D. (1) · Bettina Cuneo, MD (1) · Christophe Leclercq, MD, PhD (1) · Christopher Ellis, M.D. (1) · Gervasio Lamas (1) · Henning R Andersen, MD, DMSc (1) · Jill Buyon, MD (1) · Kerry Lee (1)
PMID 21300730, PMID 22106360, PMID 23449923, PMID 35221255, PMID 36960716, PMID 37947364
U01HL049804 (1)