94 completed, 21 unknown, 13 recruiting, 11 terminated. 52 Phase 4, 34 Phase 3, 33 Not applicable, 21 Phase 2, 13 Phase 1.
Follow Clindamycin: new trials by email Literature Review of Clindamycin trials Research Report on Clindamycin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clascoterone Versus Clindamycin Added to Adapalene/Benzoyl Peroxide for Moderate Facial Acne Clascoterone 1% cream, Clindamycin 1% lotion, Adapalene 0.1%/benzoyl peroxide 2.5% gel - Acne Vulgaris | Phase 4 | Not yet recruiting | Allied Hospital Faisalabad | 118 | 2026-11-01 | 2026-10-19 |
| Moxifloxacin Versus Clindamycin in the Management of Odontogenic Maxillofacial Infectious Processes Clindamycin, Moxifloxacin (400 mg) - Odontogenic Infection, Maxillofacial Infection | Not applicable | Not yet recruiting | Nishtar Medical University | 60 | 2026-10-01 | 2026-10-16 |
| Clindamycin as an Alternative to Vancomycin in Patients Undergoing Aortic Cardiac Surgery With Extracorporeal Circulation (ECC) Clindamycin - Aortic Surgery, Extracorporeal Circulation | Phase 2 | Recruiting | Nantes University Hospital | 25 | 2026-04-21 | 2026-04-28 |
| Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients Cefadroxil 500 mg Capsules, Clindamycin, Bactrim DS - Fracture Lower Leg, Diabetes | Phase 4 | Recruiting | Texas Tech University Health Sciences Center, El Paso | 40 | 2026-04-01 | 2026-05-08 |
| Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives) Clindamycin + primaquine, Pentamidine, Atovaquone - Pneumocystis, Pneumocystis Infection | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2026-03-01 | 2026-01-21 |
| Clostridioides Difficile Controlled Human Infection Model encapsulated 10^4 CFU toxigenic. C. difficile spores, Vancomycin, Clindamycin - C. Difficile, C. Difficile Infection | Not applicable | Not yet recruiting | Leiden University Medical Center | 60 | 2025-03-01 | 2024-11-22 |
| Laparoscopic Antibiotic Lavage to Prevent Intra-abdominal Abscess Formation in Complicated Appendicitis Laparoscopic antibiotic peritoneal lavage with gentamicin / clindamycin - Complicated Appendicitis, Intra-Abdominal Abscess | Phase 3 | Recruiting | Spaarne Gasthuis | 752 | 2025-02-24 | 2026-10-09 |
| Nasal Iodine Swab Versus Oral Antibiotic to Prevent Surgical Site Infection After Undergoing Mohs Micrographic Surgery Povidone-Iodine Swabs, Staphylococcus nasal swab, Antibiotic - Skin Cancer, Skin Cancer Face | Not applicable | Withdrawn | Mayo Clinic | 2024-09-01 | 2024-11-25 | |
| Short Versus Standard of Care Antibiotic Duration for Children Hospitalized for CAP Ampicillin for Injection, Ceftriaxone for Injection, Amoxicillin - Community Acquired Pneumonia in Children | Phase 4 | Recruiting | Medical College of Wisconsin | 236 | 2024-08-22 | 2026-03-02 |
| Efficacy of Oral vs IV Antibiotics in the Treatment of Orofacial Osteomyelitis Amoxicillin-clavulanate 875mg/125mg q12hrs, oral clindamycin 300mg q6hrs, Levofloxacin 750mg QID - Osteomyelitis of Jaw | Phase 4 | Unknown | University of Louisville | 100 | 2024-07-31 | 2024-07-17 |
| An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures Clindamycin, Doxycycline - Bacteremia, Endocarditis | Phase 4 | Unknown | University of Santiago de Compostela | 150 | 2024-07-15 | 2024-06-17 |
| Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus Bacteraemia Tab. Trimethoprim-sulfamethoxazole, Tab. Clindamycin, Tab. Cephalexin, or Tab. Linezolid, IV Cloxacillin, IV Cefazolin, IV Vancomycin, or IV Ceftaroline - Staphylococcus Aureus Bacteremia | Phase 3 | Unknown | Clinical Research Centre, Malaysia | 290 | 2024-06-28 | 2024-07-05 |
| Evaluation of Efficacy and Safety Parameters of Different Antibiotics Regimens for Management of Empyema Levofloxacin + clindamycin, Levofloxacin + cefipime - Empyema, Pleural | Not applicable | Completed | Fayoum University | 80 | 2024-05-01 | 2026-06-05 |
| Adjunctive Clindamycin for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled Trial Clindamycin, Standard of care - Skin Infection, Staphylococcal Infections | Phase 4 | Recruiting | Frieder Schaumburg | 100 | 2024-03-15 | 2024-12-09 |
| Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib Amivantamab IV, Amivantamab SC, Lazertinib - Carcinoma, Non-Small-Cell Lung | Phase 2 | Active not recruiting | Janssen Research & Development, LLC | 305 | 2024-02-16 | 2026-09-25 |
| Experience With Topical Acne Treatment clindamycin phosphate 1.2%/adapalene 0.15%/BPO 3.1% gel, adapalene 0.3%/BPO 2.5% gel and compounded clindamycin phosphate 1.2% gel, Compounded BPO 2.5% gel, adapalene 0.1% gel, and compounded clindamycin phosphate 1.2% gel - Acne | Early Phase 1 | Active not recruiting | Wake Forest University Health Sciences | 72 | 2024-02-15 | 2025-12-24 |
| CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE) Amoxicillin/clavulanate, Ciprofloxacin, Clindamycin - Cat Bite, Hand Injuries | Phase 4 | Recruiting | University of Missouri-Columbia | 72 | 2023-09-07 | 2025-10-15 |
| Urogenital Infections in Women of Reproductive Age and the Activity of 4-Thiazolidinone Derivatives Against Pathogens Microbiological identification kits (ANAEROtest, STAPHYtest, ENTEROtest, NEFERMtest), Antibiotic therapy after the results of antibiotic sensitivity test (Mostly Oxacillin, Benzylpenicillin, Ceftriaxone, Doxycycline, Clindamycin), Suppositoria for vaginal microflora recovery (Giynoflor) - Bacterial Vaginosis | Phase 1 | Active not recruiting | Danylo Halytsky Lviv National Medical University | 200 | 2023-09-01 | 2024-09-27 |
| Effect of Hebal and Synthetic Medicamentss on Enterococcus Feacalis Ibuprofen 400 mg., modified triple antibiotic paste, curcumin - Effective Intracanal Medicaments Against Enterococcus Faecalis | Phase 2 / Phase 3 | Unknown | Tanta University | 32 | 2023-08-26 | 2023-08-23 |
| Efficacy of Laser Hair Removal Therapy in HS Nd:YAG laser hair removal, Clindamycin 1 % Topical Lotion - Hidradenitis Suppurativa, Acne Inversa | Not applicable | Unknown | Erasmus Medical Center | 58 | 2023-04-01 | 2023-03-09 |
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Acne Vulgaris (36) · Infections (14) · Staphylococcal Infections (11) · Vaginosis, Bacterial (11) · Bacterial Infections (9) · Surgical Wound Infection (8) · Cellulitis (6) · Acquired Immunodeficiency Syndrome (5) · Abscess (4) · HIV Infections (4) · Pneumonia, Pneumocystis (4) · AIDS-Related Opportunistic Infections (3) · Candidiasis (3) · Diabetes Mellitus (3) · Malaria (3)
Stiefel, a GSK Company (10) · National Institute of Allergy and Infectious Diseases (NIAID) (5) · Sun Pharmaceutical Industries, Inc. (4) · Assistance Publique - Hôpitaux de Paris (2) · Centre for Human Drug Research, Netherlands (2) · Dow Pharmaceutical Sciences (2) · Duke University (2) · GlaxoSmithKline (2) · Lee's Pharmaceutical Limited (2) · Leiden University Medical Center (2) · Michael Cohen-Wolkowiez (2) · Padagis LLC (2) · Prisma Health-Upstate (2) · Teva Pharmaceuticals USA (2) · University of Louisville (2)
United States (74) · Canada (13) · France (9) · Netherlands (8) · Spain (8) · Germany (6) · Belize (5) · United Kingdom (5) · Brazil (4) · China (4) · Denmark (4) · India (4) · Israel (4) · South Africa (4) · Argentina (3)
Benoit Girard, M.D. (2) · Black JR (2) · Aaron E Chen, MD (1) · Abdelrahman Ahmed Mohamed, Teaching assistant (1) · Achim J Kaasch, MD (1) · Afsoon Roberts, M.D. (1) · Ahmed Babiker (1) · Alexander Khoruts, MD (1) · Allison R Lauver, PharmD (1)
PMID 11486303, PMID 11488820, PMID 12095065, PMID 12490869, PMID 12553848, PMID 12839559, PMID 14986270, PMID 15276398, PMID 15329363, PMID 15840453, PMID 16225607, PMID 16792648, PMID 16982292, PMID 17029531, PMID 17420365, PMID 18249468, PMID 18472984, PMID 18818959, PMID 19376456, PMID 19439902, PMID 19588358, PMID 20176900, PMID 20213916, PMID 20675299, PMID 21300243, PMID 21612850, PMID 22157324, PMID 22205034, PMID 22530208, PMID 23513559, PMID 23652892, PMID 23926058, PMID 23988422, PMID 24059911, PMID 24807330, PMID 24949994, PMID 25079934, PMID 25123767, PMID 25135090, PMID 25139552, PMID 25331703, PMID 25650692, PMID 25785967, PMID 25936632, PMID 26232669, PMID 26300919, PMID 26452342, PMID 26457865, PMID 26573073, PMID 26906190
2014 (1), 2017 (1), 2023 (1), 2025 (1), R01HD076676 (1)