62 completed, 36 recruiting, 27 unknown, 17 terminated. 163 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 163 | Completed 62, Recruiting 36, Unknown 27, Terminated 17, Not yet recruiting 12, Active not recruiting 6, Withdrawn 3 |
Follow Heart Block: new trials by email Literature Review of Heart Block trials Research Report on Heart Block
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Leadless Versus Conventional Pacemakers: Effects on Heart Function and Heart Failure Leadless pacemaker implantation, Conventional transvenous pacemaker implantation - Bradycardia, Atrioventricular Block | Not applicable | Not yet recruiting | Karl Landsteiner University of Health Sciences | 760 | 2027-11-01 | 2026-11-10 |
| Belgo-Luxembourg Leadless PM Registry CT scan heart, 24 hour ambulatory ECG monitoring - Bradyarrhythmias, AV Block Complete | Not applicable | Not yet recruiting | Universitaire Ziekenhuizen KU Leuven | 190 | 2026-11-01 | 2026-10-19 |
| LBBAP Versus ILR in Patients With New-Onset LBBB and Moderately Reduced LVEF After TAVI Left bundle branch area pacing with pacemaker, Implantation loop recorder - TAVI(Transcatheter Aortic Valve Implantation), Left Bundle Branch Block | Not applicable | Not yet recruiting | University Hospital, Clermont-Ferrand | 700 | 2026-10-15 | 2026-11-02 |
| Transjugular Approach for Implantation of Active Fixation Leadless Pacemakers Aveir VR Leadless Pacemaker - Bradycardia, Heart Block | Not applicable | Recruiting | Min Shen | 15 | 2026-10-10 | 2026-11-10 |
| Procedural Endpoint in Left Bundle Branch Area Pacing: Conduction System Capture Versus LV Septal Capture LBBAP with mandatory left ventricular conduction system capture (LBBP or LFP), LBBAP with left ventricular septal capture as the accepted procedural endpoint (LVSP) - Bradycardia, Atrioventricular Block | Not applicable | Not yet recruiting | Yonsei University | 300 | 2026-10-01 | 2026-09-04 |
| Head-to-Head (H2H) Comparison of Ambulatory Cardiac ECG Monitors in Japan Application of ambulatory cardiac monitor - Atrial Fibrillation (AF), Atrial Flutter | Not applicable | Not yet recruiting | iRhythm Technologies, Inc. | 130 | 2026-09-30 | 2026-10-19 |
| OPTImizing Lead Placement in Patients Requiring Pacemaker After Cardiac Surgery Left bundle branch area pacing, Conventional pacing strategy - Atrioventricular Block, Cardiac Surgery | Not applicable | Not yet recruiting | Sahlgrenska University Hospital | 110 | 2026-09-10 | 2026-08-31 |
| SPIKE FLOW Endocardial Lead Safety and Performance Study Lead insertion, lead removal - Acute Myocardial Infarction (AMI), Asystole | Not applicable | Recruiting | FIAB SpA | 131 | 2026-08-07 | 2026-11-12 |
| ALPs Single ChambEr New Device Leadless ventricular pacemaker implantation - Bradycardia, Brady-tachy Syndrome | Not applicable | Not yet recruiting | Cairdac SA | 10 | 2026-06-01 | 2026-03-10 |
| ALPs Single ChambEr New Device Study Leadless ventricular pacemaker implantation - Brady-tachy Syndrome, Brady Arrythmia | Not applicable | Not yet recruiting | Cairdac SA | 15 | 2026-06-01 | 2026-03-18 |
| Multimodality Location Prediction Accuracy of Leadless Pacemaker Positioning Cardiac Imaging by TTE or CTA - Sinus Pause, Sinus Sick Syndrome | Not applicable | Recruiting | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 20 | 2026-05-13 | 2026-11-02 |
| Evaluation of Accelerated Bachmann Bundle Area Pacing in Heart Failure With Reduced ejectIon Fraction Who Have electrocarDioGraphic Evidence of Interatrial Block and Indicated for Implantable Cardioverter Defibrillator BBAP on, BBAP off, RAAP - Heart Failure and Reduced Ejection Fraction | Not applicable | Not yet recruiting | Seoul National University Hospital | 120 | 2026-05-01 | 2026-04-23 |
| BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System LivIQ Leadless Pacemaker System - Leadless Pacemaker, Bradycardia | Not applicable | Recruiting | Biotronik, Inc. | 325 | 2026-03-16 | 2026-10-16 |
| Left Bundle Branch Pacing vs Right Ventricular Pacing on AHRE Burden in Patients With Preserved LVEF Right Ventricular Pacing, Left Bundle Branch Pacing - Atrial Fibrillation (AF), Pacemaker Therapy | Not applicable | Recruiting | University Hospital of Patras | 244 | 2026-02-05 | 2026-03-13 |
| LLL vs. SDL for LBBP: A Non-inferiority RCT SDL implantation, LLL implantation - Bradycardia, Conduction Block, Atrioventricular | Not applicable | Not yet recruiting | Ningbo No.2 Hospital | 288 | 2026-01-24 | 2026-02-03 |
| Efficacy and Safety of Micra AV2 Transcatheter Pacing System Implant procedure of a Micra AV2 leadless pacemaker (Medtronic) - AV Block Complete, AV Block-2Nd Degree-Type 1 | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 150 | 2026-01-12 | 2026-01-21 |
| LEAP 2 Chronic EFS AVEIR CSP Leadless Pacemaker System - Cardiac Pacemaker, Cardiac Rhythm Disorder | Not applicable | Recruiting | Abbott Medical Devices | 30 | 2025-12-13 | 2026-10-16 |
| RandomIsed sTudy of Physiologic cArdiac stimuLation in patIents With Atrio-ventricular Conduction Disease Conduction System Pacing (CSP), Right Ventricular (RV) Pacing - Atrioventricular Block | Not applicable | Recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 1260 | 2025-12-03 | 2026-05-27 |
| Central Haemodynamics and Pacing for AV Block Right ventricular pacing, Conduction system pacing - Atrioventricular Block, Pacing Therapy | Not applicable | Recruiting | University of Tartu | 124 | 2025-11-28 | 2026-03-09 |
| Trial Evaluating the Benefit of Left Bundle Branch Area Stimulation Compared With Conventional Pacing in Post-TAVI Atrioventricular Atrioventricular Block Pacemaker implantation using left bundle branch area stimulation, Right ventricular pacemaker implantation - Atrioventricular Block, Pacemaker | Not applicable | Recruiting | Nantes University Hospital | 266 | 2025-11-25 | 2026-04-15 |
Showing 20 of 163. Sign in to see all of them.
Atrioventricular Block (65) · Bundle-Branch Block (52) · Heart Failure (51) · Sick Sinus Syndrome (48) · Bradycardia (33) · Atrial Fibrillation (19) · Arrhythmias, Cardiac (14) · Aortic Valve Stenosis (6) · Heart Failure, Systolic (6) · Cardiomyopathies (5) · Neoplasm Metastasis (5) · Ventricular Dysfunction, Left (5) · Tachycardia, Ventricular (4) · Ventricular Dysfunction (4)
Cardiac Conduction System Disease (163) · Cardiovascular Diseases (163) · Pathologic Processes (163) · Pathological Conditions, Signs and Symptoms (163) · Heart Diseases (160) · Arrhythmias, Cardiac (149) · Arrhythmia, Sinus (48) · Nervous System Diseases (7) · Aortic Valve Disease (6) · Heart Valve Diseases (6) · Neurologic Manifestations (6) · Signs and Symptoms (6) · Ventricular Outflow Obstruction (6) · Consciousness Disorders (5)
Cardiac Resynchronization Therapy (12) · Defibrillators (4) · Exercise Test (2) · Blood Specimen Collection (1) · Cardiac Resynchronization Therapy Devices (1) · Catheter Ablation (1) · Clostridium perfringens epsilon-toxin (1) · Computed Tomography Angiography (1) · Device Lead Extraction (1) · Drug Implants (1) · Electrocardiography, Ambulatory (1) · Electrophysiologic Techniques, Cardiac (1) · Losartan (1) · Magnetic Resonance Spectroscopy (1) · Psychotherapy (1)
Abbott Medical Devices (10) · Medtronic Cardiac Rhythm and Heart Failure (8) · BackBeat Medical Inc (4) · Biotronik, Inc. (3) · Boston Scientific Corporation (3) · Copenhagen University Hospital, Rigshospitalet (3) · Tomsk National Research Medical Center of the Russian Academy of Sciences (3) · Universitaire Ziekenhuizen KU Leuven (3) · Aalborg University Hospital (2) · Aarhus University Hospital (2) · Azienda Ospedaliero Universitaria Maggiore della Carita (2) · Biotronik SE & Co. KG (2) · Cairdac SA (2) · Henry Ford Health System (2) · Imperial College London (2)
United States (32) · China (18) · Italy (15) · Spain (14) · United Kingdom (14) · Belgium (13) · Canada (13) · France (12) · Netherlands (12) · Denmark (11) · Austria (10) · South Korea (10) · Poland (9) · Hong Kong (7) · Czechia (6)
Karl-Heinz Kuck, Prof. MD (2) · Kevin Vernooy, MD, PhD (2) · Roman E Batalov, M.D. (2) · Tariel A Atabekov, Ph.D. (2) · Yan Wang, PhD (2) · Ajay Pillai (1) · Alessandro Capucci (1) · Alexander Dal Forno, MD (1) · Amit Noheria, MBBS, SM (1) · Andi Albertsen, MD (1) · Andre Zimerman, MD PhD (1) · Andreas S Martinsson, MD, PhD (1)
PMID 21712276, PMID 34167929, PMID 34387126, PMID 10677747, PMID 10707756, PMID 10805823, PMID 11175486, PMID 12063369, PMID 12842643, PMID 14585254, PMID 15189520, PMID 15670960, PMID 15845889, PMID 16014884, PMID 16202650, PMID 16928995, PMID 17339569, PMID 17684064, PMID 17804844, PMID 17891282, PMID 18545843, PMID 18684274, PMID 18950302, PMID 19131444, PMID 19142374, PMID 19168514, PMID 19753454, PMID 20399979, PMID 21300176, PMID 21857020, PMID 22236222, PMID 22275485, PMID 23614585, PMID 23621145, PMID 2365530, PMID 23723446, PMID 23741058, PMID 23868858, PMID 2486527, PMID 25189602, PMID 25380704, PMID 25465496, PMID 25666325, PMID 25697851, PMID 25862716, PMID 26411271, PMID 26443444, PMID 26517949, PMID 27151347, PMID 27394714
2014 (1), 2025 (1), R01HL153390 (1)