130 completed, 48 unknown, 32 terminated, 20 recruiting. 264 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 264 | Completed 130, Unknown 48, Terminated 32, Recruiting 20, Withdrawn 14, Not yet recruiting 10, Active not recruiting 7, Enrolling by invitation 3 |
Follow Fractures, Bone: new trials by email Literature Review of Fractures, Bone trials Research Report on Fractures, Bone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Suzetrigine (Journavx) as Multimodal Therapy for Pain Management in Adults Undergoing Surgery for Hip Fracture Suzetrigine (Journavx) - Hip Fractures (ICD-10 72.01-72.2), Post Operative Analgesia | Phase 4 | Not yet recruiting | Beth Israel Deaconess Medical Center | 79 | 2027-01-05 | 2026-10-29 |
| IRONCARE: Iron Treatment in Older Patients With Hip Fractures Ferric Derisomaltose, Oral Iron (Ferrous sulphate), Placebo IV - Hip Fracture, Anemia | Phase 4 | Not yet recruiting | University of Aarhus | 528 | 2026-10-01 | 2026-06-24 |
| A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements Lidocaine Infusion, Standard of Care (SOC) - Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified | Phase 4 | Recruiting | Nemours Children's Clinic | 90 | 2026-06-24 | 2026-07-06 |
| Volume Reduction for Open Fracture Irrigation 0.9% Sodium Chloride - Open Fracture | Phase 4 | Recruiting | Inova Health Care Services | 200 | 2026-03-02 | 2026-04-13 |
| Attenuate the Stress Response in Laparoscopic Cholecystectomy Dexmedetomidine, Fentanyl- midazolam - Laparoscopic Cholecystectomy Surgery | Phase 4 | Not yet recruiting | Assiut University | 50 | 2026-02-01 | 2026-02-20 |
| Haemodynamic Effects and Complications of Continuous Versus Single-shot Spinal Anaesthesia for HIP Fracture Surgery Bupivacaine Spinal 0,5% Heavy - bolus, Bupivacaine Spinal 0,5% Heavy - titration - Anesthesia, Spinal, Hip Fractures | Phase 4 | Not yet recruiting | Centre of Postgraduate Medical Education | 216 | 2026-01-15 | 2026-01-23 |
| Wrist Reduction Intervention: Supracondylar Technique for Radial Nerve Block vs. Hematoma Block (WRIST Block Study) Supracondylar radial nerve block, Hematoma block, Combination of blocks - Wrist Fracture | Phase 4 | Enrolling by invitation | Sarasota Memorial Health Care System | 105 | 2025-12-09 | 2026-10-26 |
| Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures Suzetrigine (SUZ), Placebo - Rib Fractures | Phase 4 | Enrolling by invitation | University of California, Irvine | 80 | 2025-11-13 | 2025-12-08 |
| REDUCTION ACCURACY IN NASO-ORBITO-ETHMOIDAL FRACTURES AFTER VIRTUAL REDUCTION AND FIXATION USING PRE-ADAPTED MINIPLATES pre-adapted titanium miniplates based on a virtually reduced 3D model - Naso-Orbito-Ethmoidal, Fractures | Phase 4 | Completed | Alexandria University | 15 | 2025-11-01 | 2026-10-21 |
| INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures Ropivacaine, Non steroidal anti-inflammatory drug and opioids - Rib Fractures | Phase 4 | Recruiting | Zachary Warriner | 180 | 2025-09-23 | 2026-10-29 |
| The Effect of Semaglutide on Bone Health semaglutide combined with metformin - Osteoporosis, Osteoporosis Fracture | Phase 4 | Not yet recruiting | The First Affiliated Hospital of Xiamen University | 150 | 2025-09-15 | 2025-09-17 |
| Single Shot Exparel vs Catheters in Lower Extremity Trauma Bupivacaine, Exparel + Bupivacaine - Fracture Dislocation of Ankle Joint, Fracture Leg | Phase 4 | Withdrawn | George Washington University | 2025-09-12 | 2026-09-24 | |
| Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures PENG and LFCN peripheral nerve blocks with spinal anesthesia, FN and LFCN peripheral nerve blocks with spinal anesthesia, FIC peripheral nerve block with spinal anesthesia - Fractures, Hip, Femoral Neck Fractures | Phase 4 | Not yet recruiting | University Hospital of Split | 256 | 2025-08-30 | 2025-08-19 |
| Topical TRanexamic Acid vs. Placebo on Acute Postoperative Pain Following DRF Fixation Topical TRanexamic Acid, Placebo - Distal Radius Fractures | Phase 4 | Recruiting | University Health Network, Toronto | 90 | 2025-08-13 | 2026-05-04 |
| The Effects of Intravenous Iron on Mobility in Elderly Patients Following Hip Fracture Surgery Ferric Derisomaltose, Saline (NaCl 0,9 %) (placebo) - Hip Fracture, Anemia | Phase 4 | Recruiting | Soren Overgaard | 210 | 2025-06-09 | 2026-06-01 |
| Preoperative Supra-inguinal Fascia Iliaca Block for Positioning Analgesia in Hip Fracture Patients Undergoing Spinal Anesthesia Isobaric bupivacaine 0.5% - Hip Fractures, Supra-inguinal Fascia Iliaca Block | Phase 4 | Completed | Ghurki Trust and Teaching Hospital | 132 | 2025-06-01 | 2026-04-29 |
| Clinical Trial to Evaluate Three Systems of Osteosynthesis for Fixation of Olecranon Osteotomies in Adults Fastening systems by placing two steel pins, Fastening systems by a wire in an obenque configuration, Fastening systems by the placement of a bolted plate or the placement of a compression screw - Olecranon Fracture | Phase 4 | Not yet recruiting | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 105 | 2025-06-01 | 2025-06-11 |
| Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery Buprenorphine Transdermal System, Placebo Patch - Pain, Postoperative, Ankle Fracture Surgery | Phase 4 | Recruiting | Jenna-Leigh Wilson | 100 | 2025-04-21 | 2026-04-06 |
| Compression Therapy for Swelling Management Following Ankle Injury Compression sleeve - Ankle Fracture, Ankle Arthrodesis | Phase 4 | Not yet recruiting | Nova Scotia Health Authority | 50 | 2025-04-01 | 2025-01-24 |
| IMPLICATION OF FAST-TRACK PROTOCOL FOR HIP FRACTURE FIXATION IN ALEXANDRIA UNIVERSITY HOSPITALS Fast-track protocol for hip fracture fixation - Fast-track Protocol, Hip Fracture | Phase 4 | Completed | Alexandria University | 150 | 2025-04-01 | 2025-12-15 |
Showing 20 of 264. Sign in to see all of them.
Hip Fractures (73) · Osteoporosis (25) · Femoral Neck Fractures (21) · Rib Fractures (19) · Wrist Fractures (19) · Pain (18) · Pain, Postoperative (16) · Agnosia (15) · Fractures, Open (13) · Ankle Fractures (12) · Femoral Fractures (12) · Fractures, Stress (12) · Bone Diseases, Metabolic (10) · Wounds and Injuries (10)
Wounds and Injuries (254) · Leg Injuries (121) · Hip Injuries (90) · Femoral Fractures (89) · Pathological Conditions, Signs and Symptoms (79) · Signs and Symptoms (57) · Neurologic Manifestations (55) · Pathologic Processes (44) · Musculoskeletal Diseases (42) · Nervous System Diseases (34) · Bone Diseases (31) · Nutritional and Metabolic Diseases (29) · Arm Injuries (28) · Metabolic Diseases (28)
Sodium Chloride (23) · Ropivacaine (18) · Bupivacaine (16) · Tranexamic Acid (14) · Acetaminophen (12) · Saline Solution (12) · Morphine (11) · Zoledronic Acid (10) · Ibuprofen (9) · Calcium (8) · Vitamin D (8) · Dexamethasone (6) · Dexmedetomidine (6) · Lidocaine (6) · Oxycodone (6)
AO Clinical Investigation and Publishing Documentation (8) · University of Aarhus (6) · Alexandria University (5) · Hvidovre University Hospital (5) · The University of Hong Kong (4) · Ankara City Hospital Bilkent (3) · Insel Gruppe AG, University Hospital Bern (3) · Mahidol University (3) · Odense University Hospital (3) · Rothman Institute Orthopaedics (3) · Susan L. Greenspan (3) · Cork University Hospital (2) · Emory University (2) · Hospital Clinic of Barcelona (2) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (2)
United States (88) · Canada (19) · Denmark (18) · Spain (18) · China (15) · Germany (13) · Switzerland (13) · United Kingdom (9) · Egypt (7) · France (7) · Norway (7) · Turkey (Türkiye) (7) · Austria (6) · South Korea (6) · Ireland (5)
Nicolai B Foss, MD (3) · Susan L Greenspan, MD (3) · Beate P. Hanson, MD (2) · Eric Swart, MD (2) · Gerard Slobogean, MD (2) · Jamal Ahmad, M.D. (2) · Karen E Hansen, MD (2) · Mohit Bhandari, MD (2) · Rune Dueholm Bech, MD (2) · Sheila Sprague, PhD (2) · Thomas F. Bendtsen, MD, Ph.d. (2) · Aasis Unnanuntana, MD (1) · Abraham Goch, MD (1) · Ahmed Shehab, MD (1)
PMID 33238043, PMID 12548273, PMID 17413915, PMID 18762870, PMID 32259266, PMID 32787892, PMID 1015603, PMID 10636366, PMID 10691239, PMID 11063900, PMID 11331167, PMID 11331334, PMID 11374619, PMID 11472277, PMID 1180371, PMID 12411815, PMID 12477942, PMID 12560416, PMID 12900694, PMID 14105897, PMID 14622770, PMID 1489023, PMID 15227616, PMID 1536396, PMID 15755432, PMID 16056035, PMID 16490909, PMID 17138203, PMID 17414553, PMID 17414554, PMID 17443116, PMID 17638186, PMID 17916782, PMID 18039992, PMID 18056740, PMID 18378867, PMID 18686750, PMID 19051059, PMID 19157368, PMID 19174373, PMID 19291931, PMID 19389209, PMID 19594305, PMID 19624576, PMID 19690943, PMID 19926634, PMID 19934395, PMID 19996801, PMID 20124051, PMID 20178889
2015 (2), 2016 (2), 2017 (2), 2009 (1), R01AG050302 (1), R01AG052123 (1), R01AG059417 (1), R01AG066825 (1), R01HL065523 (1)