26 completed, 7 recruiting, 5 unknown, 4 terminated. 47 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 47 | Completed 26, Recruiting 7, Unknown 5, Terminated 4, Not yet recruiting 2, Withdrawn 2, Enrolling by invitation 1 |
| Phase 2 | 6 | Completed 2, Unknown 2, Recruiting 1, Terminated 1 |
Follow Emergencies: new trials by email Literature Review of Emergencies trials Research Report on Emergencies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Morphine or Ketamine for Analgesia Ketamine hydrochloride, Morphine sulphate - Abdominal Pain, Isolated Extremity Fracture | Phase 3 | Recruiting | Columbia University | 1010 | 2026-10-17 | 2026-10-20 |
| Atomized Intranasal Ketorolac at 30 mg Versus 20 mg for the Treatment of Acute Pain in the Emergency Department 20mg intranasal ketorolac, 30mg Intranasal Ketorolac - Pain, Ketorolac | Phase 3 | Not yet recruiting | Tehran University of Medical Sciences | 100 | 2026-10-10 | 2026-09-16 |
| Methoxyflurane Versus Usual Care for Non-Traumatic Pain in Emergency Departments Analgesic management with Methoxyflurane as first-line treatment, Pain treatment according to the usual analgesic management protocol of the emergency department of the participating center. - Pain Management | Phase 3 | Not yet recruiting | University Hospital, Tours | 164 | 2026-09-16 | 2026-08-03 |
| Eptinezumab as an Adjunct to Standard of Care for Migraine in an Acute Emergency Context Eptinezumab, Standard of Care - Migraine, Chronic Migraine | Phase 3 | Enrolling by invitation | Dr George Medvedev | 102 | 2025-05-05 | 2026-09-30 |
| Emergency Department-Initiated Medications for Alcohol Use Disorder Naltrexone Pill, Naltrexone Injection, Brief Negotiation Interview - Alcohol Use Disorder | Phase 3 | Recruiting | Yale University | 240 | 2024-08-17 | 2026-07-21 |
| RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing Rivaroxaban 10 MG, Low Heparin Molecular Weight - Venous Thromboembolism, Deep Vein Thrombosis | Phase 3 | Recruiting | University Hospital, Angers | 1424 | 2024-07-19 | 2026-06-25 |
| A Randomized Study Comparing of Three Doses Nebulized Fentanyl in Older Adults Nebulized fentanyl - Treatment Side Effects, Musculoskeletal Pain | Phase 3 | Completed | Bangkok Metropolitan Administration Medical College and Vajira Hospital | 120 | 2024-07-01 | 2026-10-02 |
| Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal Pain Ketorolac Tromethamine, Morphine Sulfate, normal saline - Acute Pain, Abdomen, Acute | Phase 3 | Recruiting | University of Calgary | 495 | 2024-05-27 | 2024-06-24 |
| Early Initiated Vasopressor Therapy in the Emergency Department Noradrenaline - Shock, Shock, Septic | Phase 3 | Recruiting | Odense University Hospital | 320 | 2023-12-08 | 2025-07-01 |
| Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation Ketamine Hydrochloride, Normal saline - Suicidal Ideation | Phase 3 | Unknown | University of Ottawa | 20 | 2023-06-01 | 2023-02-13 |
| Effect of Short-Term Prednisone Therapy on C-Reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers ( CORTAHF ) Prednisone arm, Usual care - Acute Heart Failure | Phase 2 / Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 3 | 2023-02-16 | 2026-01-21 |
| Ketamine & Crisis Response Plan for Suicidal Ideation in the ED Ketamine Hydrochloride, Crisis Response Plan - Suicide | Phase 2 / Phase 3 | Recruiting | The University of Texas Health Science Center at San Antonio | 24 | 2023-01-06 | 2026-09-30 |
| IV Iron Trial for Anemia Related to Uterine Bleeding in Female Patients Presenting to the Emergency Department Ferric Derisomaltose 1000 Mg in 10 mL INTRAVENOUS SOLUTION [Monoferric], Ferrous Sulfate 65 mg elemental iron (325 mg tablets) - Anemia, Iron Deficiency, Uterine Bleeding | Phase 3 | Recruiting | Baylor College of Medicine | 40 | 2022-09-15 | 2024-12-05 |
| A Pilot Clinical Trial of a New Neuromodulation Device for Acute Attacks of Migraine in Children and Adolescents Ketorolac, Metoclopramide, Active Remote Electrical Neuromodulation Device - Migraine Disorders | Phase 3 | Completed | University of Calgary | 22 | 2022-02-22 | 2025-03-12 |
| Ketorolac for Moderate to Severe Abdominal Pain in Children Ketorolac Tromethamine 10 MG/ML, Morphine Sulfate 10Mg/1mL Injection - Abdominal Pain, Appendicitis | Phase 3 | Completed | Hamilton Health Sciences Corporation | 105 | 2021-05-05 | 2023-02-28 |
| Virginia Opioid Treatment-Emergency Department SUBLOCADE - Opioid Use Disorder | Phase 3 | Withdrawn | Virginia Commonwealth University | 2021-01-01 | 2021-02-12 | |
| IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department Patients IV acetaminophen, IV placebo, hydromorphone - Acute Pain | Phase 3 | Completed | Albert Einstein College of Medicine | 162 | 2018-11-27 | 2022-03-02 |
| Intranasal Lidocaine to Treat Pediatric Migraine in the Emergency Department Lidocaine, Placebo - Migraine | Phase 3 | Unknown | New York City Health and Hospitals Corporation | 50 | 2018-10-15 | 2021-01-05 |
| Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department Ibuprofen, Lidocaine Patch 4% - Acute Musculoskeletal Disease, Sprains | Phase 3 | Completed | East Carolina University | 23 | 2018-06-23 | 2024-03-25 |
| Inhaled vs IV Opioid Dosing for the Initial Treatment of Severe Acute Pain in the Emergency Department inhaled titration of morphine chlorhydrate, IV placebo, Inhaled placebo - Pain, Acute, Emergencies | Phase 3 | Completed | University Hospital, Rouen | 226 | 2017-09-19 | 2026-02-06 |
Showing 20 of 47. Sign in to see all of them.
Pain (8) · Acute Pain (7) · Agnosia (4) · Migraine Disorders (4) · Abdominal Pain (3) · Asthma (3) · Suicidal Ideation (3) · Wounds and Injuries (3) · Acute Coronary Syndrome (2) · Alcoholism (2) · Appendicitis (2) · Depression (2) · Gastroenteritis (2) · Myocardial Infarction (2)
Disease Attributes (47) · Pathologic Processes (47) · Pathological Conditions, Signs and Symptoms (47) · Neurologic Manifestations (20) · Signs and Symptoms (20) · Nervous System Diseases (10) · Pain (8) · Behavior (7) · Mental Disorders (6) · Neurobehavioral Manifestations (6) · Behavioral Symptoms (5) · Cardiovascular Diseases (5) · Chemically-Induced Disorders (5) · Brain Diseases (4) · Central Nervous System Diseases (4)
Morphine (5) · Hydromorphone (4) · Ketamine (4) · Saline Solution (4) · Ketorolac Tromethamine (3) · Sodium Chloride (3) · Dexamethasone (2) · Methoxyflurane (2) · Standard of Care (2) · Acetaminophen (1) · Albuterol (1) · Blood Specimen Collection (1) · Budesonide (1) · Budesonide, Formoterol Fumarate Drug Combination (1) · Calcium Dobesilate (1)
Montefiore Medical Center (5) · Assistance Publique - Hôpitaux de Paris (3) · University of British Columbia (3) · University Hospital, Rouen (2) · University of Calgary (2) · Albert Einstein College of Medicine (1) · AstraZeneca (1) · Bangkok Metropolitan Administration Medical College and Vajira Hospital (1) · Baylor College of Medicine (1) · Centre Hospitalier Annecy Genevois (1) · Columbia University (1) · Dr George Medvedev (1) · East Carolina University (1) · Geoffrey W Jara-Almonte (1) · Hadassah Medical Organization (1)
United States (19) · Canada (11) · France (9) · Denmark (1) · Israel (1) · Spain (1) · Sweden (1) · Thailand (1) · Tunisia (1)
Mohamed Eltorki, MBChB (2) · Alan Peterson, PhD, ABPP (1) · Alan S Maisel, MD (1) · Alberto Borobia, MD, PhD (1) · Amy L Drendel, DO, MS (1) · Andrew Chang, M.D. (1) · Andrew K Chang, MD (1) · Benjamin W Friedman, MD, MS (1) · Benjamin W. Friedman, MD, MS (1) · Brian Rowe, MD (1) · Cheryl McCullumsmith, MD PhD (1) · Christopher Kelly, MD (1) · Daniel S Tsze, MD, MPH (1) · Delphine Douillet, Doctor (1) · Edward Bernstein, MD (1)
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2023 (2), 2009 (1), 2025 (1), R01AA030568 (1), R21AA015123 (1), U01HD116253 (1), UL1TR002645 (1)