18 completed, 6 recruiting, 4 unknown, 2 withdrawn. 31 Phase 2, 5 Phase 1, 5 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 31 | Completed 18, Recruiting 6, Unknown 4, Withdrawn 2, Terminated 1 |
| Phase 1 | 5 | Completed 2, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 5 | Completed 5 |
Follow Dysphagia: new trials by email Literature Review of Dysphagia trials Research Report on Dysphagia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Digital Intelligent Tongue-Pressure Biofeedback Resistance Training for Post-Stroke Dysphagia: A Randomized Controlled Trial Digital Intelligent Tongue-Pressure Biofeedback Resistance Training, Conventional Tongue-Pressure Resistance Training - Dysphagia, Stroke | Phase 2 | Recruiting | First People's Hospital of Foshan | 80 | 2026-06-05 | 2026-09-01 |
| Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease In-person sEMG-biofeedback, Remote sEMG-biofeedback, Standard-of-care treatment - Dysphagia, Stroke | Phase 2 | Recruiting | University of Illinois at Urbana-Champaign | 120 | 2025-07-22 | 2026-10-16 |
| Corticosteroids for Post-Extubation Dysphagia Methylprednisolone, Normal Saline - Dysphagia, Laryngeal Edema | Phase 2 | Recruiting | University of Colorado, Denver | 80 | 2024-12-02 | 2026-05-06 |
| Neuromuscular Electrical Stimulation for Children With Dysphagia VitalStim - Dysphagia | Phase 2 | Unknown | Sir Mortimer B. Davis - Jewish General Hospital | 10 | 2024-03-01 | 2024-03-13 |
| Innovative Patient-partner-guided Virtual Group Speech Pathology Intervention Model in Head and Neck Cancer virtual group speech therapy intervention guided by a patient partner - Dysphagia | Phase 1 / Phase 2 | Recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 76 | 2023-06-02 | 2025-03-21 |
| Rehabilitation of Airway Protection in Parkinson's Disease Expiratory Muscle Strength Training + Cough Skill Training - Parkinson Disease, Dysphagia | Phase 2 | Recruiting | Teachers College, Columbia University | 120 | 2022-08-11 | 2026-10-08 |
| Adaptive RadioTherapy for OroPharynx Cancer Standard radiotherapy +/- chemotherapy, Experimental radiotherapy +/- chemotherapy - Oropharynx Cancer, Radiotherapy; Complications | Phase 2 | Recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 120 | 2021-07-30 | 2026-08-24 |
| Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery Esomeprazole, Placebo Oral Tablet - Dysphagia, GERD | Phase 2 | Withdrawn | Icahn School of Medicine at Mount Sinai | 2020-07-01 | 2020-11-23 | |
| Treatment of Dysphagia and Ineffective Esophageal Motility With Prucalopride: A Pilot Study Prucalopride - Ineffective Esophageal Motility, Dysphagia | Phase 2 | Completed | University of Calgary | 28 | 2017-10-20 | 2020-03-25 |
| Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial EMST, smTAP - Parkinson's Disease, Dysphagia | Phase 2 | Completed | Teachers College, Columbia University | 65 | 2016-09-01 | 2023-12-22 |
| Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia Dietary and oral hygiene recommendations, oral TRPV1 agonist, pharyngeal electrical stimulation - Dysphagia, Aspiration | Phase 2 | Completed | Hospital de Mataró | 100 | 2012-10-01 | 2017-02-09 |
| A Pilot Study of ALTENS in Improving Dysphagia Induced by IMRT for Head and Neck Cancers Codetron ALTENS - Head and Neck Cancer, Dysphagia | Phase 1 / Phase 2 | Unknown | McMaster University | 35 | 2012-10-01 | 2012-10-02 |
| Predictors of Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis dexlansoprazole - Gastroesophageal Reflux Disease, Eosinophilic Esophagitis | Phase 1 / Phase 2 | Withdrawn | Mayo Clinic | 2012-03-01 | 2012-04-19 | |
| Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy For Lung Cancer Manuka honey in liquid form, Manuka honey in lozenge form, Standard supportive care - Dysphagia, Lung Cancer | Phase 2 | Completed | Radiation Therapy Oncology Group | 163 | 2012-02-01 | 2017-08-31 |
| The Effect of Repetitive Transcranial Magnetic Stimulation for Poststroke Dysphagia Recovery rTMS, Magstim Rapid2 - Stroke, Dysphagia | Phase 2 | Unknown | Taipei Veterans General Hospital, Taiwan | 50 | 2011-12-01 | 2014-03-18 |
| Tongue Pressure Profile Training for Dysphagia Post Stroke Tongue Pressure Profile Training, Tongue-Pressure Strength-and-Accuracy Training - Dysphagia | Phase 2 | Completed | Toronto Rehabilitation Institute | 14 | 2011-09-01 | 2016-02-08 |
| Neuromuscular Electrical Stimulation (NMES) Treatment Technique Therapy in the Management of Young Infants With Severe Dysphagia Neuromuscular electrical stimulation (NMES) - Dysphagia | Phase 2 | Completed | The Hospital for Sick Children | 10 | 2010-09-01 | 2015-07-20 |
| Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia Modafinil, Placebo, Baseline - Spatial Neglect, Dysphagia | Phase 2 | Completed | University of Arkansas | 28 | 2010-03-01 | 2016-10-18 |
| Functional Electrical Stimulation in Irradiated Nasopharyngeal Carcinoma (NPC) Functional electrical stimulation, Exercise home program - Dysphagia | Phase 2 | Completed | National Taiwan University Hospital | 20 | 2008-07-01 | 2014-03-26 |
| Adjunctive Neuromuscular Electrical Stimulation for the Rehabilitation of Swallowing swallowing therapy - Dysphagia | Phase 2 / Phase 3 | Completed | University of Florida | 53 | 2008-04-01 | 2012-01-05 |
Showing 20 of 31. Sign in to see all of them.
Deglutition Disorders (31) · Stroke (11) · Gastroesophageal Reflux (3) · Head and Neck Neoplasms (3) · Parkinson Disease (3) · Carcinoma, Non-Small-Cell Lung (2) · Lung Neoplasms (2) · Radiation Injuries (2) · Cough (1) · Eosinophilic Esophagitis (1) · Esophageal Ring, Lower (1) · Esophagitis (1) · Joint Diseases (1) · Laryngeal Edema (1) · Malnutrition (1)
Digestive System Diseases (31) · Esophageal Diseases (31) · Gastrointestinal Diseases (31) · Otorhinolaryngologic Diseases (31) · Pharyngeal Diseases (31) · Brain Diseases (13) · Central Nervous System Diseases (13) · Nervous System Diseases (13) · Cardiovascular Diseases (11) · Cerebrovascular Disorders (11) · Vascular Diseases (11) · Neoplasms (7) · Neoplasms by Site (7) · Respiratory Tract Diseases (4) · Basal Ganglia Diseases (3)
Amifostine (1) · BaseLine dental cement (1) · Carboplatin (1) · Dexlansoprazole (1) · Diet (1) · Electrodes (1) · Esomeprazole (1) · Fibroblast Growth Factor 7 (1) · Methylprednisolone (1) · Modafinil (1) · Noble Gases (1) · Nutritional Support (1) · Paclitaxel (1) · Radiotherapy (1) · Range of Motion, Articular (1)
Centre hospitalier de l'Université de Montréal (CHUM) (2) · Teachers College, Columbia University (2) · University of Arkansas (2) · University of Florida (2) · Beth Israel Deaconess Medical Center (1) · Federal University of São Paulo (1) · First People's Hospital of Foshan (1) · Hospital de Mataró (1) · Icahn School of Medicine at Mount Sinai (1) · Mayo Clinic (1) · McMaster University (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · National Taiwan University Hospital (1) · Ostfold Hospital Trust (1) · Radiation Therapy Oncology Group (1)
United States (15) · Canada (6) · Australia (2) · Brazil (1) · China (1) · Norway (1) · Spain (1) · Taiwan (1)
Giselle Carnaby-Mann, PhD (2) · Andrew C Hecht, MD (1) · Barbara A. Murphy, MD (1) · Catriona M Steele, Ph.D. (1) · Gary H McCullough, Ph.D. (1) · Gary McCullough, PhD (1) · Georgia Malandraki, PhD (1) · Giselle D Mann, MPH,PhD (1) · Graeme Hankey, MBBS, MD, (1) · James A DiSario, M.D. (1) · Jeffrey A Alexander, MD (1) · Joanne Robbins, PhD (1) · John Fang, M.D. (1) · Katia Alonso, PHD (1) · Lawrence B. Berk, MD, PhD (1)
PMID 16137276, PMID 16361020, PMID 17270511, PMID 17602265, PMID 20176418, PMID 20955603, PMID 21441148, PMID 23782628, PMID 30740545, PMID 36345090, PMID 42032732
2023 (1), R01AG086371 (1), R01NS126319 (1), R03DC004942 (1), R21AG089278 (1), R21HD054752 (1), R21HD055677 (1)