Radiation Injuries: Clinical Trials

322 completed, 191 unknown, 151 recruiting, 55 terminated. 259 Not applicable, 165 Phase 2, 90 Phase 3, 49 Phase 1, 19 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	259	Completed 86, Unknown 59, Recruiting 54, Not yet recruiting 19, Terminated 14, Active not recruiting 13, Withdrawn 12, Enrolling by invitation 1, Suspended 1
Phase 2	165	Completed 62, Unknown 44, Recruiting 24, Terminated 21, Not yet recruiting 6, Active not recruiting 4, Withdrawn 3, Enrolling by invitation 1
Phase 3	90	Completed 47, Unknown 17, Recruiting 13, Terminated 6, Not yet recruiting 4, Active not recruiting 1, Enrolling by invitation 1, Suspended 1
Phase 1	49	Completed 26, Unknown 9, Terminated 7, Recruiting 3, Not yet recruiting 2, Active not recruiting 1, Withdrawn 1
Phase 4	19	Completed 9, Recruiting 3, Unknown 3, Active not recruiting 2, Not yet recruiting 1, Terminated 1
Early Phase 1	11	Completed 3, Recruiting 3, Active not recruiting 1, Suspended 1, Terminated 1, Unknown 1, Withdrawn 1

Follow this condition Literature Review of Radiation Injuries trials Research Report on Radiation Injuries

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Risk Factors of Jaw Osteoradionecrosis in Oral Cavity Cancer Patients Post-Radiotherapy Osteoradionecrosis, Radiotherapy		Not yet recruiting	AO Innovation Translation Center	1000	2027-03-01	2026-09-23
Maximizing Quality of Life After Cancer Through Rehabilitation TIMELY REHAB - Head and Neck Cancer, Hearing Loss	Not applicable	Not yet recruiting	VA Office of Research and Development	74	2027-03-01	2026-06-03
Platelet-Rich Fibrin for Preventing Osteoradionecrosis After Dental Extractions Platelet-rich fibrin (PRF), Standard Dental Extraction Care - Osteoradionecrosis of the Jaw	Not applicable	Not yet recruiting	University of Manitoba	112	2027-01-01	2026-10-05
PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study Clinical Decision Aid, Standard Care - Heart Failure, Coronary Artery Disease		Not yet recruiting	Medical College of Wisconsin	60	2026-12-01	2025-10-14
Positron Emission Tomography (PET) Imaging of Chemotherapy-Induced Cardiotoxicity 68Ga-Galmydar, PET/MRI, 18F-FDG - Lymphoma Cancer, Breast Cancer	Phase 1	Not yet recruiting	Washington University School of Medicine	36	2026-11-01	2026-09-24
Oral Care Program for Mouth Side Effects During Head and Neck Radiation Therapy ORAL CARE PRODUCT KIT - Head and Neck Cancer (H&N), Oral Mucositis (Ulcerative) Due to Radiation	Not applicable	Not yet recruiting	UNCANCER LLC	50	2026-11-01	2026-10-21
Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE) Mobile Cardiac Telemetry, Wearable Cardiac Monitor - Cardiotoxicity, Cancer	Not applicable	Not yet recruiting	University of Minnesota	72	2026-10-29	2026-10-06
Cardiac Biomarkers in Patients Receiving Immune Checkpoint Inhibitors (PRIME-ICI) Cardiotoxicity, Cardiac Biomarkers		Not yet recruiting	South Tees Hospitals NHS Foundation Trust	300	2026-10-12	2026-10-08
OCTA Evaluated the Efficacy of Glucocorticoid Retrobulbar Injection in Retinal Photo-injury retrobulbar injection of glucocorticoid - Retinal Light Damage, Photic Retinopathy		Recruiting	Second Affiliated Hospital, Zhejiang University, School of Medicine	50	2026-10-09	2026-10-09
Cardioprotection Effect of Linagliptin Doxorubicin, Empaglifloz 5 mg orally once daily - Cardiotoxicity	Phase 3	Not yet recruiting	Tanta University	140	2026-10-01	2026-10-15
Oral or Topical Catechins for Radiation Dermatitis Epicatechin, Epigallocatechin Gallate (EGCG), Microcrystalline Cellulose NF (placebo) - Radiation Dermatitis Acute, Radiation Dermatitis	Phase 3	Enrolling by invitation	CARLOS FRANCISCO SAAVEDRA GARCIA	162	2026-10-01	2026-09-11
An App to Identify Radiation Pneumonitis - a Pre-Study in Healthy Volunteers PneumoCheck app - Lung Cancer	Not applicable	Not yet recruiting	University Hospital Schleswig-Holstein	30	2026-09-28	2026-09-17
Heart Failure in Women: Epidemiological and Prognostic Insights Heart Failure		Recruiting	Carolina Ortiz Cortes	430	2026-09-17	2026-10-21
A Study of Chlorophyllin or Placebo With Standard Treatment for Late Radiation Induced Luminal Gastrointestinal Tract Bleeding Chlorophyllin, Sodium Copper Complex, Placebo - Radiation Proctitis, Gastrointestinal Hemorrhage	Phase 3	Not yet recruiting	Tata Memorial Centre	200	2026-09-15	2026-09-23
OCCUPATIONAL NOISE AND CHEMICAL EXPOSURE EFFECTS ON AUDITORY AND VESTIBULAR FUNCTION Occupational Noise Exposure		Not yet recruiting	Ondokuz Mayıs University	50	2026-09-03	2026-09-08
PRISM Trial: Partial Breast Versus Whole Breast Radiation in Early Breast Cancer Ultra-Hypofractionated Partial Breast Irradiation, Ultra-Hypofractionated Whole Breast Irradiation - Breast Cancer Early Stage Breast Cancer (Stage 1-3)	Not applicable	Not yet recruiting	Jinnah Postgraduate Medical Centre	100	2026-09-01	2026-09-10
Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC) PET/CT 18F-Flurpiridaz Rest/Stress Test, Coronary CT Angiography (CCTA), 18F-Flurpiridaz - Non Small Cell Lung Cancer, Cardiotoxicity	Phase 2	Recruiting	Indiana University	10	2026-09-01	2026-09-15
The CARDIOPROTECT Trial Dexrazoxane, Dexrazoxane placebo, Doxorubicin - Diffuse Large B-cell Lymphoma (DLBCL), Cardiotoxicity	Phase 2	Recruiting	Beth Israel Deaconess Medical Center	60	2026-08-31	2026-07-27
Topical Boswellia Serrata 2% to Prevent Radiation Dermatitis in Head and Neck Cancer Boswellia serrata 2% topical cream - Head and Neck Neoplasms, Radiodermatitis	Not applicable	Recruiting	Youssef Hashem Hafez	60	2026-08-18	2026-08-21
Multi-Omics Prediction of Radiation Lung Injury in Immunotherapy-Treated Lung Cancer Patients No Intervention: Observational Cohort - Lung Cancer (NSCLC), Lung Cancer (SCLC)		Not yet recruiting	HAN GUANG	160	2026-08-15	2026-08-03

Showing 20 of 831. Sign in to see all of them.

Narrower conditions

Cardiotoxicity (255)  ·  Breast Neoplasms (201)  ·  Radiodermatitis (125)  ·  Neoplasms (84)  ·  Head and Neck Neoplasms (83)  ·  Ototoxicity (49)  ·  Heart Failure (45)  ·  Lung Neoplasms (40)  ·  Radiation Pneumonitis (39)  ·  Prostatic Neoplasms (31)  ·  Carcinoma, Non-Small-Cell Lung (29)  ·  Lymphoma (24)  ·  Brain Neoplasms (23)  ·  Osteoradionecrosis (20)

Broader conditions

Wounds and Injuries (829)  ·  Neoplasms (466)  ·  Neoplasms by Site (449)  ·  Pathological Conditions, Signs and Symptoms (403)  ·  Pathologic Processes (381)  ·  Chemically-Induced Disorders (327)  ·  Drug-Related Side Effects and Adverse Reactions (308)  ·  Skin and Connective Tissue Diseases (277)  ·  Skin Diseases (274)  ·  Cardiovascular Diseases (254)  ·  Heart Diseases (253)  ·  Breast Diseases (202)  ·  Dermatitis (117)  ·  Neoplasms by Histologic Type (104)

Interventions

Radiotherapy (53)  ·  Cisplatin (20)  ·  Doxorubicin (19)  ·  Echocardiography (18)  ·  Cyclophosphamide (12)  ·  Radiotherapy, Intensity-Modulated (12)  ·  Amifostine (11)  ·  Dexrazoxane (10)  ·  Low-Level Light Therapy (10)  ·  Standard of Care (10)  ·  Exercise (9)  ·  Paclitaxel (9)  ·  Radiosurgery (9)  ·  Blood Specimen Collection (8)  ·  Carboplatin (8)

Sponsors

Radiation Therapy Oncology Group (16)  ·  Wake Forest University Health Sciences (14)  ·  Abramson Cancer Center at Penn Medicine (11)  ·  National Cancer Institute (NCI) (9)  ·  Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (9)  ·  University of Aarhus (9)  ·  West China Hospital (9)  ·  Assistance Publique - Hôpitaux de Paris (8)  ·  Mayo Clinic (8)  ·  Royal Marsden NHS Foundation Trust (8)  ·  Sunnybrook Health Sciences Centre (8)  ·  Ain Shams University (7)  ·  Cancer Institute and Hospital, Chinese Academy of Medical Sciences (7)  ·  Children's Oncology Group (7)  ·  AHS Cancer Control Alberta (6)

Countries

United States (222)  ·  China (95)  ·  Canada (70)  ·  France (53)  ·  United Kingdom (39)  ·  Italy (29)  ·  Egypt (28)  ·  Brazil (26)  ·  Denmark (26)  ·  Spain (23)  ·  Netherlands (19)  ·  Belgium (18)  ·  Turkey (Türkiye) (16)  ·  Australia (15)  ·  Israel (15)

Top investigators

Bonnie Ky, MD, MSCE (6)  ·  Xingchen Peng (5)  ·  Edward LW Chow, MBBS (4)  ·  Bernardino Clavo, MD, PhD (3)  ·  Cafer Zorkun, MD PhD (3)  ·  Jingfang Mao, PHD (3)  ·  John P Carey, MD (3)  ·  John R. Yarnold, MD, FRCR (3)  ·  Marielle Scherrer-Crosbie, MD, PhD (3)  ·  Scott Okuno, MD (3)  ·  Aminah Jatoi, MD (2)  ·  Anthony Yu, MD (2)  ·  Benjamin Movsas, MD (2)  ·  Chris Nutting (2)  ·  Cindy Schwartz, MD (2)

Results publications

PMID 31723056, PMID 15992242, PMID 22105041, PMID 23102757, PMID 23215625, PMID 26357522, PMID 30271455, PMID 32379556, PMID 33738491, PMID 36207229, PMID 42032732, PMID 10071296, PMID 10443466, PMID 10459293, PMID 10761937, PMID 11173128, PMID 11263649, PMID 11744442, PMID 11901547, PMID 11913479, PMID 11917283, PMID 12011138, PMID 12800204, PMID 12948221, PMID 13211322, PMID 14349898, PMID 14566480, PMID 15050309, PMID 15183474, PMID 15222781, PMID 15473335, PMID 15477280, PMID 15480814, PMID 15800308, PMID 15812073, PMID 16015544, PMID 16027437, PMID 16131888, PMID 16332601, PMID 16549835, PMID 16568436, PMID 16823067, PMID 16841333, PMID 16893745, PMID 16980242, PMID 17047036, PMID 17050868, PMID 17068719, PMID 17293228, PMID 17336213

NIH funding

2023 (5), P30CA012197 (5), U10CA081851 (4), 2018 (2), P30CA015083 (2), P30CA068485 (2), U01DC019364 (2), U01DE022939 (2), 2009 (1), 2014 (1), 2016 (1), 2019 (1), I01CX000569 (1), K08CA259626 (1), N01CM62202 (1)