67 completed, 5 terminated, 5 unknown, 4 recruiting. 82 Phase 3, 11 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 82 | Completed 67, Terminated 5, Unknown 5, Recruiting 4, Not yet recruiting 1 |
| Phase 2 | 11 | Completed 8, Unknown 2, Terminated 1 |
Follow Duodenal Diseases: new trials by email Literature Review of Duodenal Diseases trials Research Report on Duodenal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 3 to Evaluate the Efficacy and Safety of DWP14012 in Patients With Gastric Ulcer DWP14012 40mg (Fexuprazan), Lansoprazole 30mg - Gastric Ulcer | Phase 3 | Not yet recruiting | Daewoong Pharmaceutical Co. LTD. | 384 | 2026-10-15 | 2026-07-28 |
| A Clinical Trial of Anaprazole for Treating Reflux Esophagitis. Anaprazole + Rabeprazole placebo, Rabeprazole + Anaprazole placebo - Reflux Esophagitis (RE) | Phase 3 | Recruiting | Xuanzhu Biopharmaceutical Co., Ltd. | 500 | 2025-07-30 | 2025-09-29 |
| A Phase III Clinical Trial for Efficacy and Safety Evaluation of JP-1366 Tablets on Reflux Esophagitis JP-1366 simulation tablets, Esomeprazole Magnesium (Nexium) simulation tablets - Reflux Esophagitis (RE) | Phase 3 | Recruiting | Livzon Pharmaceutical Group Inc. | 356 | 2024-12-05 | 2025-02-27 |
| Study to Evaluate the Efficacy and Safety of JP-1366 in the Prevention of NSAIDs-Induced Peptic Ulcers JP-1366 10 mg, Lanston Capsule 15 mg, JP-1366 10 mg placebo - Peptic Ulcer | Phase 3 | Recruiting | Onconic Therapeutics Inc. | 364 | 2024-10-22 | 2024-11-01 |
| Study to Evaluate the Efficacy and Safety of Ilaprazole 10 mg in Prevention NSAIDs Associated Peptic Ulcer Ilaprazole, Lansoprazole, Ilaprazole Placebo - Peptic Ulcer | Phase 3 | Recruiting | Il-Yang Pharm. Co., Ltd. | 416 | 2024-07-23 | 2025-05-30 |
| A Study to Evaluate the Effiacy and Safety of HIP0612 in Patients With Gastric Ulcer HIP0612, HPP2202, RLD2204 - Gastric Ulcer | Phase 3 | Completed | Hanmi Pharmaceutical Company Limited | 199 | 2023-03-06 | 2025-02-19 |
| Clinical Trial to Evaluate the Efficacy and Safety of JP-1366 in Patients With Gastric Ulcer JP-1366 20mg, Lansoprazole 30mg - Gastric Ulcer | Phase 3 | Completed | Onconic Therapeutics Inc. | 329 | 2022-09-19 | 2024-08-26 |
| The Efficacy and Safety of DWP14012 in Chinese Patients With Reflux Esophagitis DWP14012 - Reflux Esophagitis | Phase 3 | Completed | Daewoong Pharmaceutical Co. LTD. | 332 | 2021-12-30 | 2023-04-14 |
| Efficacy and Safety of LXI-15028 Comparing With Lansoprazole in the Treatment of Duodenal Ulcer LXI-15028 50mg group, Lansoprazole 30mg group - Duodenal Ulcer | Phase 3 | Completed | Shandong Luoxin Pharmaceutical Group Stock Co., Ltd. | 400 | 2021-10-18 | 2023-04-25 |
| The Phase III Clinical Trial of X842 Capsules for Reflux Esophagitis X842, X842 Placebo, Lansoprazole - Reflux Esophagitis | Phase 3 | Completed | Jiangsu Sinorda Biomedicine Co., Ltd | 380 | 2021-06-24 | 2025-07-23 |
| Study to Evaluate the Efficacy and Safety of DWP14012 in Prevention of NSAIDs Induced Peptic Ulcer DWP14012 20mg, Lansoprazole 15 mg, DWP14012 20mg placebo - Peptic Ulcer | Phase 3 | Completed | Daewoong Pharmaceutical Co. LTD. | 423 | 2021-05-21 | 2024-07-08 |
| A Study of Esomeplazole (D961H) in Japanese Paediatric Patients With Reflux Esophagitis, Gastric Ulcer or Duodenal Ulcer D961H capsule 10mg, D961H sachet 10mg - Reflux Esophagitis, Gastric Ulcer | Phase 3 | Completed | AstraZeneca | 50 | 2018-07-24 | 2026-03-04 |
| Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Gastric Ulcer Participants With or Without Helicobacter Pylori Infection TAK-438, Lansoprazole, TAK-438 Placebo - Gastric Ulcer | Phase 3 | Completed | Takeda | 234 | 2017-04-17 | 2021-06-18 |
| Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Duodenal Ulcer Participants With or Without Helicobacter Pylori Infection TAK-438, Lansoprazole, TAK-438 Placebo - Duodenal Ulcer | Phase 3 | Completed | Takeda | 533 | 2017-04-05 | 2020-06-12 |
| Proton Pump Inhibitor Plus Propranolol Versus Proton Pump Inhibitor Alone on Peptic Ulcer Healing in Patients With Liver Cirrhosis Proton-pump inhibitor, Propranolol+Proton-pump inhibitor - Liver Cirrhosis, Peptic Ulcer | Phase 2 / Phase 3 | Terminated | Taipei Veterans General Hospital, Taiwan | 10 | 2016-12-26 | 2020-06-23 |
| Treatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based Therapy Deferiprone, Acetylcysteine, Sitagliptin and Metformin - Diabetes Mellitus, Iron Metabolism Disorders | Phase 2 / Phase 3 | Unknown | Hadassah Medical Organization | 20 | 2016-12-01 | 2016-08-29 |
| Efficacy of DA-5204 on Gastroesophageal Reflux Disease Pantoprazole, DA-5204, Placebo - Esophageal Disease | Phase 3 | Completed | Seoul National University Hospital | 70 | 2016-06-01 | 2019-06-26 |
| Study to Evaluate the Safety and Efficacy of CJ-12420 in Patients With Gastric Ulcer CJ-12420 50 mg QD, CJ-12420 100 mg QD, Lansoprazole 30 mg QD - Gastric Ulcer | Phase 3 | Completed | HK inno.N Corporation | 306 | 2016-05-01 | 2019-08-22 |
| Magnetic-controlled Capsule Endoscopy vs. Gastroscopy for Detection of Gastric Diseases MCE, Standard gastroscopy - Gastric Diseases,, Gastric Ulcer, | Phase 3 | Completed | Changhai Hospital | 350 | 2014-08-01 | 2015-07-21 |
| Cytoprotective Agent and Peptic Ulcer in Dual Antiplatelet :RCT Repamipide, Placebo - Gastric Ulcer Induced by Anti-platelet Agent, Duodenal Ulcer Induced by Anti-platelet Agent | Phase 2 / Phase 3 | Completed | King Chulalongkorn Memorial Hospital | 142 | 2014-07-01 | 2019-02-27 |
Showing 20 of 82. Sign in to see all of them.
Stomach Ulcer (43) · Duodenal Ulcer (27) · Esophagitis, Peptic (19) · Peptic Ulcer (18) · Osteoarthritis (7) · Gastroesophageal Reflux (6) · Arthritis, Rheumatoid (5) · Gastritis (4) · Arthritis (3) · Digestive System Diseases (2) · Duodenal Neoplasms (2) · Gastrointestinal Diseases (2) · Gastrointestinal Hemorrhage (2) · Helicobacter Infections (2) · Low Back Pain (2)
Intestinal Diseases (81) · Digestive System Diseases (80) · Gastrointestinal Diseases (80) · Stomach Diseases (79) · Peptic Ulcer (62) · Gastroenteritis (23) · Esophageal Diseases (20) · Esophagitis (19) · Pathological Conditions, Signs and Symptoms (10) · Joint Diseases (8) · Musculoskeletal Diseases (8) · Rheumatic Diseases (7) · Deglutition Disorders (6) · Esophageal Motility Disorders (6)
Lansoprazole (25) · Esomeprazole (17) · 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine (10) · Omeprazole (7) · Naproxen (6) · Pantoprazole (6) · Rabeprazole (6) · Dexlansoprazole (5) · ilaprazole (4) · Celecoxib (3) · Ranitidine (3) · fexuprazan (3) · Amoxicillin (2) · Aspirin (2) · Clarithromycin (2)
Takeda (19) · AstraZeneca (15) · POZEN (8) · Daewoong Pharmaceutical Co. LTD. (3) · Eisai Co., Ltd. (3) · Livzon Pharmaceutical Group Inc. (3) · Chinese University of Hong Kong (2) · Hamamatsu University (2) · Il-Yang Pharm. Co., Ltd. (2) · Onconic Therapeutics Inc. (2) · Amgen (1) · Casa Sollievo della Sofferenza IRCCS (1) · Changhai Hospital (1) · Cogentus Pharmaceuticals (1) · Federal University of Mato Grosso (1)
Japan (24) · United States (16) · South Korea (14) · China (13) · Australia (5) · Canada (5) · Czechia (5) · Germany (5) · Slovakia (5) · Taiwan (5) · Bulgaria (4) · Poland (4) · Italy (3) · Latvia (3) · Lithuania (3)
Everardus Orlemans, PhD (4) · Paula Fernstrom (4) · Francis K Chan, MD (2) · Maotsugu Oyama, MD, PhD (2) · Naotsugu Oyama (2) · Nobuyuki Sugisaki (2) · Andriulli Angelo, MD (1) · Angelo Zullo, MD (1) · Bjorn WH van Heumen, MD (1) · Chieh-Chang Chen, MD (1) · David Zangen, Professor (1) · Dong Ho Lee, MD, PhD (1)
PMID 19735233, PMID 20195905, PMID 21129076, PMID 19183157, PMID 19681809, PMID 23451835, PMID 24118079, PMID 27891632, PMID 28988197, PMID 29196436, PMID 39085080, PMID 12641522, PMID 17916545, PMID 19086953, PMID 19210298, PMID 20379093, PMID 20925534, PMID 21319944, PMID 21415072, PMID 22070512, PMID 22591121, PMID 23188121, PMID 23530709, PMID 23919274, PMID 24245549, PMID 24326741, PMID 26036878, PMID 26165391, PMID 26725920, PMID 27012778, PMID 27211503, PMID 30919492, PMID 38251791, PMID 38910891, PMID 39378042, PMID 40567214, PMID 41540828
2018 (1)