43 completed, 7 terminated, 4 unknown, 4 withdrawn. 19 Phase 1, 13 Phase 4, 12 Phase 2, 10 Phase 3, 5 Not applicable.
Follow Ranitidine: new trials by email Literature Review of Ranitidine trials Research Report on Ranitidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2 Study of Isatuximab in Combination With Pomalidomide and Dexamethasone in MM Patients Who Received One Prior Line of Therapy Containing Lenalidomide and a Proteasome Inhibitor Isatuximab, Pomalidomide, Dexamethasone - Multiple Myeloma, Renal Impairment | Phase 2 | Unknown | Hellenic Society of Hematology | 108 | 2022-05-01 | 2022-03-28 |
| Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel Cimetidine, Dexamethasone, Diphenhydramine - Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | Phase 2 / Phase 3 | Completed | Ohio State University Comprehensive Cancer Center | 130 | 2021-10-07 | 2025-08-20 |
| Effect of H2 Receptor Antagonist and Proton Pump Inhibitor on the Positivity Rates and Clinical Outcomes of COVID-19 No intervention (Retrospective Cohort Observational) - COVID-19 | Completed | Seoul National University Hospital | 400000 | 2021-05-01 | 2024-11-29 | |
| Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies Acetaminophen, Dexamethasone, Diphenhydramine - Recurrent Acute Leukemia, Recurrent B Acute Lymphoblastic Leukemia | Phase 1 | Completed | City of Hope Medical Center | 13 | 2020-11-18 | 2026-01-28 |
| Safety, Pharmacokinetics, and Preliminary Efficacy of Isatuximab in Patients Awaiting Kidney Transplantation Isatuximab SAR650984, Acetaminophen (paracetamol) or equivalent, Ranitidine or equivalent - Immune System Disorder | Phase 1 / Phase 2 | Terminated | Sanofi | 23 | 2020-06-18 | 2025-09-17 |
| Clinical Study to Investigate the Urinary Excretion of N-nitrosodimethylamine (NDMA) After Ranitidine Administration Ranitidine, Placebo, Low nitrite/NDMA meals - Ranitidine Adverse Reaction, Pharmacokinetics | Phase 1 | Completed | Food and Drug Administration (FDA) | 18 | 2020-06-08 | 2021-08-09 |
| Study of H2 Antagonist and a Proton Pump Inhibitor of Selpercatinib in Healthy Participants Selpercatinib, Ranitidine, Omeprazole - Healthy | Phase 1 | Completed | Eli Lilly and Company | 20 | 2019-07-08 | 2024-10-30 |
| Nefopam vs Tramadol in the Prevention of Post Anaesthetic Shivering Nefopam, Tramadol, Metoclopramide - Post Anaesthetic Shivering | Phase 2 | Unknown | Lagos State Health Service Commission | 130 | 2018-10-12 | 2018-07-17 |
| Effect of Anti-histamine in Prevention Systolic Hypotension After Protamine Chlorpheniramine and ranitidine, 0.9% Normal Saline - Protamine Adverse Reaction | Phase 4 | Completed | Mahidol University | 40 | 2018-09-05 | 2021-09-01 |
| Histamine Receptor 2 Antagonists as Enhancers of Anti-Tumour Immunity Ranitidine - Cancer | Phase 4 | Completed | Nova Scotia Health Authority | 30 | 2018-05-01 | 2023-02-08 |
| A Crossover Study to Assess the Drug-drug Interaction of Acid Reducing Agent(s) on the Pharmacokinetics of a Single Oral Dose of Lumicitabine (JNJ-64041575) in Healthy Adult Participants Lumicitabine, Lansoprazole, Ranitidine - Healthy | Phase 1 | Terminated | Janssen Research & Development, LLC | 18 | 2018-03-06 | 2018-07-23 |
| A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMT Alemtuzumab GZ402673, Glatiramer acetate, Beta-Interferon - Multiple Sclerosis | Phase 3 | Terminated | Genzyme, a Sanofi Company | 16 | 2017-10-23 | 2026-08-04 |
| Safety and Efficacy of Isatuximab in Lymphoblastic Leukemia Isatuximab SAR650984, dexamethasone, acetaminophen - T-cell Type Acute Leukemia-Precursor, T-lymphoblastic Lymphoma/Leukaemia | Phase 2 | Terminated | Sanofi | 14 | 2017-03-08 | 2022-03-21 |
| Laparoscopic Cholecystectomy: General Anesthesia With Opioid Versus General Opioid Free Anesthesia dexter ketamine, Lidocaine Hydrochloride, Fentanyl Hydrochloride - Pain, Postoperative, Anesthesia Complication | Phase 4 | Unknown | Federal University of São Paulo | 40 | 2016-11-01 | 2016-11-04 |
| Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1 intravenous infusion of 2 mg trospium chloride, oral administration of 30 mg trospium chloride, oral administration of 300 mg ranitidine - Pharmacokinetics, Inhibition Enzyme | Phase 1 | Completed | Dr. R. Pfleger Chemische Fabrik GmbH | 24 | 2016-11-01 | 2017-04-10 |
| Sublingual Misoprostol to Reduce Blood Loss During Elective Cesarean Delivery Misoprostol Oral Tablet, Ranitidine Oral Tablet - Hemorrhage Postpartum | Phase 2 | Unknown | Ain Shams Maternity Hospital | 158 | 2016-07-01 | 2017-05-04 |
| In Infants With Laryngomalacia, Does Acid-Blocking Medication Improve Respiratory Symptoms? ranitidine or famotidine, Placebo - Laryngomalacia, Acid Reflux | Not applicable | Withdrawn | Stanford University | 2016-02-01 | 2017-11-17 | |
| Combination of Cabazitaxel With Prednisolone With Primary Prophylaxis With PEG-G-CSF in Treatment of Patients With Prostate Cancer CABAZITAXEL XRP6258, PEG-G-CSF, Prednisolone - Prostate Cancer | Phase 4 | Completed | Sanofi | 21 | 2015-04-01 | 2017-01-24 |
| Management Of The Infusion-Associated Reactions In RRMS Patients Treated With LEMTRADA Alemtuzumab GZ402673, cetirizine, ranitidine - Relapsing-remitting Multiple Sclerosis | Phase 4 | Completed | Genzyme, a Sanofi Company | 58 | 2014-10-01 | 2016-06-09 |
| Lesinurad Interaction Study With Ranitidine lesinurad 400 mg, ranitidine 150 mg, lesinurad 400 mg + ranitidine 150 mg - Healthy | Phase 1 | Completed | Ardea Biosciences, Inc. | 16 | 2013-07-01 | 2014-01-09 |
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Gastroesophageal Reflux (7) · Dyspepsia (4) · Stomach Ulcer (3) · Breast Neoplasms (2) · Disease (2) · HIV Infections (2) · Neoplasms (2) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (2) · Acquired Immunodeficiency Syndrome (1) · Anaphylaxis (1) · Blastic Plasmacytoid Dendritic Cell Neoplasm (1) · Blood Protein Disorders (1) · Brain Neoplasms (1) · Breast Carcinoma In Situ (1) · Burkitt Lymphoma (1)
AstraZeneca (4) · Sanofi (4) · Boehringer Ingelheim (3) · Eisai Inc. (2) · Eli Lilly and Company (2) · Genzyme, a Sanofi Company (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Ain Shams Maternity Hospital (1) · Akdeniz University (1) · Ardea Biosciences, Inc. (1) · Canadian Network for Observational Drug Effect Studies, CNODES (1) · City of Hope Medical Center (1) · D. Walter Wray (1) · Dr. R. Pfleger Chemische Fabrik GmbH (1) · Dr. Reddy's Laboratories Limited (1)
United States (26) · Canada (4) · United Kingdom (4) · France (3) · Turkey (Türkiye) (3) · Belgium (2) · Italy (2) · Japan (2) · Netherlands (2) · Russia (2) · South Korea (2) · Spain (2) · Australia (1) · Austria (1) · Brazil (1)
Paula Fernstrom (2) · Alyn H Morice, Professor (1) · Andre Knottnerus, MD, PhD (1) · Cenker Eken, Proffesor (1) · Christian Madl, MD (1) · Christopher D O'Brien, MD PHD (1) · Colleen Nalepinski, MPAS, PA-C (1) · DM Kornhauser (1) · David W Wray, Ph.D. (1) · Douglas R Sidell, MD (1) · Eleanor Lisbon, MD (1)
PMID 10662747, PMID 11904109, PMID 11927799, PMID 12119802, PMID 12832331, PMID 15066944, PMID 15710782, PMID 15738343, PMID 17515447, PMID 17515448, PMID 17959952, PMID 19150702, PMID 19540518, PMID 20179242, PMID 20837887, PMID 22311903, PMID 22607579, PMID 23856153, PMID 25117183, PMID 26403509, PMID 27271310, PMID 27289472, PMID 28395507, PMID 31329922, PMID 34180947, PMID 34376579, PMID 35622074, PMID 36571171, PMID 38147137, PMID 39102302, PMID 39134120, PMID 39727053, PMID 41331127, PMID 9727818
2016 (2), 2014 (1), 2017 (1), 2019 (1), P30CA033572 (1)