6 completed, 5 unknown, 3 recruiting, 1 not yet recruiting. 15 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 15 | Completed 6, Unknown 5, Recruiting 3, Not yet recruiting 1 |
Follow Drug Effect: new trials by email Literature Review of Drug Effect trials Research Report on Drug Effect
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GLP-1R Actions on Muscle and the Skeleton Tirzepatide, Lifestyle toolkit - Musculoskeletal Abnormalities, Obesity | Phase 4 | Recruiting | Pennington Biomedical Research Center | 50 | 2025-10-09 | 2026-08-27 |
| Randomized Comparison of Morning Versus Bedtime Administration of Statins: A Cardiovascular Circadian Chronotherapy (C3) Trial Statin in the evening (such as Simvastatin, Atorvastatin, Rosuvastatin, Pravastatin), Statin in the morning (such as Simvastatin, Atorvastatin, Rosuvastatin, Pravastatin) - Cardiovascular Diseases (CVD), Drug Effect | Phase 4 | Not yet recruiting | Tor Biering-Sørensen | 42000 | 2025-02-28 | 2025-03-04 |
| The Effect and Mechanism of Xiqing Regulating Intestinal Homeostasis on Drug Efficacy of Chronic Kidney Disease Xiqing, probiotics - CKD, Drug Effect | Phase 4 | Recruiting | Chujin Cao | 120 | 2024-06-07 | 2025-09-19 |
| Randomized Comparison of Morning Versus Bedtime Administration of Aspirin: A Cardiovascular Circadian Chronotherapy (C3) Trial Aspirin - Atherosclerosis, Cardiovascular Diseases | Phase 4 | Recruiting | Tor Biering-Sørensen | 32706 | 2024-01-15 | 2024-02-06 |
| Flurbiprofen Tablet vs Spray In Oral Soft Tissue Wounds Flurbiprofen - Oral Soft Tissue Conditions, Drug Effect | Phase 4 | Completed | Yuzuncu Yil University | 40 | 2023-10-26 | 2024-07-26 |
| Parathyroid Hormone Level and Growth in Pediatric Patients With ESRD on Regular Hemodialysis Cinacalcet - Drug Effect | Phase 4 | Completed | Tanta University | 35 | 2023-08-05 | 2024-01-24 |
| A Prospective, Randomized, Controlled Study of rhTPO in Combination With Herombopag + CsA vs Herombopag + CsA for the Treatment of Primary TD-NSAA Herombopag + CsA, rhTPO combined with Herombopag + CsA - Aplastic Anemia, Drug Effect | Phase 4 | Unknown | Peking Union Medical College Hospital | 90 | 2023-08-01 | 2023-08-22 |
| Remimazolam Improves the Safety in Elderly Patients Undergoing Gastrointestinal Endoscopy Remimazolam, Propofol group - Anesthetics, Recovery | Phase 4 | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 300 | 2022-07-10 | 2022-07-01 |
| GLP-1 Therapy: The Role of IL-6 Signaling and Adipose Tissue Remodeling in Metabolic Response Cyanocobalamin, Dulaglutide - Glucose Intolerance, Overweight and Obesity | Phase 4 | Completed | The University of Texas Health Science Center, Houston | 23 | 2020-05-15 | 2024-12-05 |
| Comparision of Different Doses of Dexmedetomidine With Low Dose Bupivacaine in Selective Spinal Anesthesia. Dexmedetomidine, placebo - Drug Effect | Phase 4 | Unknown | Services Institute of Medical Sciences, Pakistan | 75 | 2019-09-02 | 2019-08-21 |
| Oral Dydrogesterone vs. Micronized Vaginal Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer Cycles Dydrogesterone 10 MG Oral Tablet, Progesterone Vaginal Gel [Crinone] - Infertility, Female, Infertility, Male | Phase 4 | Unknown | Memorial Sisli Hospital, Istanbul | 140 | 2019-01-02 | 2019-10-14 |
| Comparison of the Efficacy and Safety of Two Homologous Active Principles for Local Dental Anesthesia Articaine / EPINEPHrine Cartridge - Drug Effect, Tooth Extraction | Phase 4 | Completed | Universidad de Antioquia | 179 | 2018-09-04 | 2021-05-12 |
| Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures Liposomal bupivacaine injection, Bupivacaine indwelling catheter - Drug Effect, Rib Fractures | Phase 4 | Completed | Denver Health and Hospital Authority | 36 | 2017-10-05 | 2021-09-29 |
| Effects of Switching From Racemic Methadone to R-methadone on QTc Intervals Same individuals treated with racemic methadone and switched to levomethadone (R-methadone) - Adverse Drug Effect, Drug Effect | Phase 4 | Unknown | Oslo University Hospital | 10 | 2015-05-07 | 2024-04-03 |
| Comparing the Effects of Levobupivacaine and Bupivacaine in Saddle Spinal Anesthesia Levobupivacaine (as Levobupivacaine Hydrochloride) 75 Mg/10 mL Solution for Injection Ampoule, Bupivacaine/Dextrose - Outpatients, General Surgery | Phase 4 | Completed | Gazi University | 60 | 2007-11-21 | 2020-01-29 |
Cardiovascular Diseases (2) · Obesity (2) · Agnosia (1) · Anemia, Aplastic (1) · Arrhythmias, Cardiac (1) · Atherosclerosis (1) · Drug-Related Side Effects and Adverse Reactions (1) · Glucose Intolerance (1) · Helping Behavior (1) · Infertility, Female (1) · Infertility, Male (1) · Musculoskeletal Abnormalities (1) · Neuralgia (1) · Opioid-Related Disorders (1) · Osteoporosis (1)
Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (4) · Body Weight (2) · Chemically-Induced Disorders (2) · Metabolic Diseases (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Nutrition Disorders (2) · Nutritional and Metabolic Diseases (2) · Overnutrition (2) · Anemia (1) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Behavior (1) · Bone Diseases (1)
Aspirin (1) · Atorvastatin (1) · Bupivacaine (1) · Carticaine (1) · Cinacalcet (1) · Crinone (1) · Dexmedetomidine (1) · Dosage Forms (1) · Dydrogesterone (1) · Flurbiprofen (1) · Glucose (1) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (1) · Levobupivacaine (1) · Pravastatin (1) · Probiotics (1)
Tor Biering-Sørensen (2) · Chujin Cao (1) · Denver Health and Hospital Authority (1) · First Affiliated Hospital Xi'an Jiaotong University (1) · Gazi University (1) · Memorial Sisli Hospital, Istanbul (1) · Oslo University Hospital (1) · Peking Union Medical College Hospital (1) · Pennington Biomedical Research Center (1) · Services Institute of Medical Sciences, Pakistan (1) · Tanta University (1) · The University of Texas Health Science Center, Houston (1) · Universidad de Antioquia (1) · Yuzuncu Yil University (1)
China (3) · United States (3) · Denmark (2) · Turkey (Türkiye) (2) · Colombia (1) · Egypt (1) · Norway (1) · Pakistan (1)
Absalon D Gutierrez, MD (1) · Cennet N Eroglu, DDS,PhD (1) · Fabian Jaimes, MD, PhD (1) · Fredric Pieracci, MD MPH (1) · Manan Pareek, MD, PhD (1) · Mimi Stokke S Opdal, MD, PhD (1) · Peter Krajci, MD, PhD (1) · Qiang Wang (1) · Sara Mabrouk Mohamed Elghoul, MD (1) · Semra Kahraman, Prof (1) · Ying Yao, PhD (1)
PMID 10028738, PMID 10832257, PMID 12366885, PMID 15966499, PMID 17082283, PMID 18762633, PMID 20006669, PMID 21772732, PMID 22915899, PMID 26868800, PMID 33951024, PMID 34195402
R21DK122234 (1)