38 completed, 25 unknown, 2 not yet recruiting, 2 recruiting. 21 Not applicable, 20 Phase 3, 16 Phase 4, 7 Phase 2, 2 Early Phase 1.
Follow Dydrogesterone: new trials by email Literature Review of Dydrogesterone trials Research Report on Dydrogesterone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Oral Dydrogesterone and Vaginal Progesterone in Menopausal Hormone Therapy Dydrogesterone 10 MG Oral Tablet, Micronized progesterone 200 MG, Transdermal estradiol - Menopausal Women, Menopausal Symptom Relief | Not applicable | Not yet recruiting | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | 200 | 2026-04-01 | 2026-03-27 |
| Comparison of Dydrogesterone Alone Versus Dydrogesterone Plus HCG in Threatened Miscarriage Dydrogesterone, Human chorionic gonadotrophin (hCG) - Threatened Miscarriage, Early Pregnancy Bleeding | Not applicable | Completed | Pakistan Air Force (PAF) Hospital Islamabad | 100 | 2025-12-09 | 2026-05-27 |
| Efficacy of Oral Contraceptive, Progesterone, and Inositol on Menstrual Regulation in PCOS Combined Oral Contraceptive (Ethinylestradiol 0.03 mg + Drospirenone 3 mg), Inositol mid-level volume, Dydrogesterone Pill - Polycystic Ovary Syndrome (PCOS) | Not applicable | Recruiting | Ege University | 150 | 2025-12-01 | 2025-12-18 |
| Study of the Effectiveness of Dydrogesterone in the Treatment of Endometriosis-related Pain Dydrogesterone - Endometriosis | Not yet recruiting | Abbott | 250 | 2025-04-01 | 2025-04-30 | |
| Study on the Effect of Combined Estrogen and Progestogen Therapy on Endometrial Repair After Induced Abortion 17β-estradiol/dydrogesterone tablets - Pregnancy Complications | Phase 1 | Unknown | Women's Hospital School Of Medicine Zhejiang University | 200 | 2024-05-09 | 2025-08-28 |
| PPOS vs GnRH Antagonist in Ovarian Stimulation (ProGanOS Study) Dydrogesterone 10 mg, Cetrorelix 0.25 mg - Progestins Primed Ovarian Stimulation | Not applicable | Active not recruiting | Mỹ Đức Hospital | 626 | 2024-04-24 | 2026-03-20 |
| Progesterone Primed Protocol Versus GnRH Antagonist in With PCO Undergoing ICSI Dydrogesterone Tablets, Cetrorelix - IVF, PCO | Phase 2 / Phase 3 | Completed | Beni-Suef University | 200 | 2024-01-01 | 2026-04-15 |
| Progesterone Primed Ovarian Stimulation Versus GnRH Antagonist Protocols in Women With Polycystic Ovarian Syndrome Progesterone, GnRH antagonist (Cetrorelix) - Controlled Ovarian Hyperstimulation, Polycystic Ovarian Syndrome | Completed | El Shatby University Hospital for Obstetrics and Gynecology | 100 | 2023-12-01 | 2025-02-25 | |
| Dydrogesterone, Cetrorelix Acetate and Triptorelin in Intra Cytoplasmic Sperm Injection Outcomes Dydrogesterone, Cetrorelix acetate, Triptorelin - IVF | Phase 3 | Unknown | Beni-Suef University | 387 | 2023-07-15 | 2023-08-02 |
| Progesterone Primed Ovarian Stimulation Protocol Versus Antagonist Protocol for PCO Patient Progesterone antagonist, conventional antagonist protocol - Polycystic Ovary Syndrome, Infertility | Not applicable | Unknown | Fayoum University | 210 | 2023-06-01 | 2023-05-06 |
| Luteal Phase Ovarian Stimulation With Follitropin Delta and Dydrogesterone Follitropin delta (Rekovelle), Duphaston, GnRH agonist (Gonapeptyl) - Oocyte Donors, Oocyte Donation | Not applicable | Unknown | CRG UZ Brussel | 50 | 2023-04-01 | 2024-02-08 |
| Comparison of 3 Different Protocols for Preventing Premature Ovulation in Ovarian Stimulation Cycles Gonadotropin releasing hormone antagonist (Cetrotide), Medroxyprogesterone Acetate (Tarlusal), Dydrogesterone - Infertility | Not applicable | Completed | Bezmialem Vakif University | 297 | 2023-03-15 | 2024-10-15 |
| Dydrogesterone-Primed Ovarian Stimulation Protocol Versus Gonadotropin Releasing Hormone Antagonist Protocol in ICSI progestin primed ovarian stimulation protocol, dydrogesterone (Duphaston, Abbott), Cetrotide - Ovary Cyst, Fertility Issues | Not applicable | Unknown | Zagazig University | 79 | 2023-02-20 | 2023-03-02 |
| PPOS Protocol Versus GnRH Anatagonist for Expected Normal Responder Patients Undergoing ART : a Randomized Clinical Trial Dydrogesterone Oral Tablet, Cetrorelix (Cetrotide) - PPOS, GnRH Antagonist | Phase 3 | Completed | Kasr El Aini Hospital | 328 | 2023-01-03 | 2025-03-11 |
| The Rescue of Hormonal Replacement Frozen Embryo Transfer Cycle With Low Serum Progesterone. Duphaston, prolutex - Hormonal Replacement Frozen Embryo Transfer Cycle | Phase 2 / Phase 3 | Unknown | El Shatby University Hospital for Obstetrics and Gynecology | 120 | 2023-01-01 | 2023-03-07 |
| Didroxyprogesterone Promotes Natural Pregnancy in Infertile Patients With Endometriosis didroxyprogesterone - Pregnancy Rate | Phase 3 | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 300 | 2022-12-10 | 2022-07-21 |
| The Effect of Pretreatment With Dydrogesterone Vs Combined Estradiol Valerate and Dydrogestrone on Clinical Pregnancy Outcome of ICSI in PCOS Patients" dydrogesterone 20 mg /d (Duphaston, Abott Healthcare , Egypt), estradiol valerate 2 mg /d (white tablets of cycloprognova, Bayer Shering, Germany) - PCOS, ICSI | Early Phase 1 | Unknown | Sohag University | 500 | 2022-05-01 | 2022-04-14 |
| Addition of Dydrogesterone to the Luteal Phase Support After Fresh Embryo Transfer Dydrogesterone 10mg Oral Tablet - Infertility, IVF | Not applicable | Unknown | Laniado Hospital | 300 | 2022-04-01 | 2021-10-04 |
| Comparative Study to Evaluate the Efficacy and Safety of the Fixed-dose Combination of Estradiol / Dydrogesterone in Perimenopausal Women Femoston® 1, Femoston® 2, Duphaston, Klimadynon - Perimenopausal Disorder, Hot Flashes | Phase 4 | Unknown | Scientific Research Institute of Public Health, Russian Federation | 150 | 2021-11-29 | 2022-01-06 |
| Progestin-primed Ovarian Stimulation Protocol Versus GnRH Antagonist Protocol in Polycystic Ovary Syndrome Patients Undergoing IVF/ICSI Cycles Dydrogesterone Tablets, cetrorelix 0.25mg, human menopausal gonadotropin - PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries | Not applicable | Unknown | Mansoura University | 200 | 2021-11-01 | 2021-11-09 |
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Infertility (10) · Infertility, Female (9) · Endometriosis (5) · Abortion, Threatened (4) · Obstetric Labor, Premature (4) · Polycystic Ovary Syndrome (4) · Abortion, Habitual (3) · Gynatresia (3) · Premature Birth (2) · Abortion, Spontaneous (1) · Genital Diseases, Female (1) · Genital Diseases, Male (1) · Helping Behavior (1) · Hot Flashes (1) · Idiopathic Hypogonadotropic Hypogonadism (1)
Abbott (5) · CRG UZ Brussel (3) · Chulalongkorn University (3) · El Shatby University Hospital for Obstetrics and Gynecology (3) · ShangHai Ji Ai Genetics & IVF Institute (3) · Solvay Pharmaceuticals (3) · The University of Hong Kong (3) · Assiut University (2) · Beni-Suef University (2) · Fudan University (2) · Mỹ Đức Hospital (2) · Peking Union Medical College Hospital (2) · Abbott Products (1) · Affiliated Hospital of Nantong University (1) · Ain Shams University (1)
China (17) · Egypt (10) · Russia (7) · Thailand (6) · Turkey (Türkiye) (6) · Belgium (5) · Croatia (3) · Israel (3) · Malaysia (3) · Poland (3) · Vietnam (3) · Austria (2) · Germany (2) · Hong Kong (2) · Romania (2)
Vorapong Phupong, M.D. (3) · Aijun Sun, MD (1) · Aly A Hussein, Ass.lecturer (1) · Aly A Hussein, Dr (1) · Andrey V Kozachenko, Prof (1) · Christophe Blockeel (1) · Christophe Blockeel, Prof, MD (1) · Dajin Li, MD (1) · Darline Cheatham-Seitz, MD, PhD (1) · Duan Hua, PhD (1) · Emre Pabuccu, Assoc. Prof. (1) · Ernest HY Ng, MD (1)
PMID 18275573, PMID 22086108, PMID 25956370, PMID 26945402, PMID 27428219, PMID 30304457, PMID 109276, PMID 12536358, PMID 14516934, PMID 14667881, PMID 15380145, PMID 15901258, PMID 16293412, PMID 16672246, PMID 17555751, PMID 18181085, PMID 20005647, PMID 20007011, PMID 21273126, PMID 21371705, PMID 21563131, PMID 21691164, PMID 21967664, PMID 22525900, PMID 24127952, PMID 24807871, PMID 2492234, PMID 25622239, PMID 26020402, PMID 26207230, PMID 26856618, PMID 27060174, PMID 27126581, PMID 27233760, PMID 27406348, PMID 27534747, PMID 27761732, PMID 27999118, PMID 28062551, PMID 28333318, PMID 28609128, PMID 29320655, PMID 29338855, PMID 30927417, PMID 32000820, PMID 33331637, PMID 33509129, PMID 34262403, PMID 34465452, PMID 38272383
2004 (3), 2018 (1)