130 completed, 36 recruiting, 33 unknown, 24 not yet recruiting. 120 Not applicable, 32 Phase 1, 31 Phase 2, 24 Phase 4, 16 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dynamic Treatment Regimes for Opioid Use Disorder Medication for opioid use disorder, psychotherapy - Opioid Use Disorder | Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 75 | 2028-07-01 | 2025-11-04 |
| Personalizing Mental Health Treatment for Youth and Families Culturally Responsive Assessment, Formulation, and Treatment Tool (CRAFTT), Cultural Formulation Interview, Modular Approach to Therapy for Children - Anxiety, Traumatic Stress | Not applicable | Not yet recruiting | University of Oregon | 64 | 2027-01-01 | 2026-02-20 |
| Pain and Movement Responses to Resistance Training to Muscular Failure in Patients With Patellofemoral Pain EXERCISE TRAINING WITH OR WITHOUT MEDICATION - Patellofemoral Pain Syndrome | Not yet recruiting | Ted Gunhamn | 30 | 2026-12-01 | 2026-09-28 | |
| Modality Choice Before and After Failure for the Treatment of Painful Diabetic Neuropathy Cognitive Behavioral Therapy (CBT), Oral Medication, Topical Medication - Painful Diabetic Neuropathy (PDN), Diabetic Nephropathies | Phase 4 | Not yet recruiting | University of Michigan | 600 | 2026-11-01 | 2026-10-21 |
| Decode the Environment Variation of Targeted Aldosterone Inducer and siLencer Aldosterone circulation, Medication, Operation - Hypertension, Aldosteronemia | Not applicable | Not yet recruiting | DejthidaNathaphong | 100 | 2026-10-10 | 2026-10-01 |
| Coordinated Access for Addiction Recovery and Equity in VA Supportive Housing Medication for Addiction Treatment (MAT), Cognitive Behavioral Therapy for Substance Use Disorders (CBT-SUD) - Homelessness, Substance Use Disorder (SUD) | Not applicable | Enrolling by invitation | VA Office of Research and Development | 7908 | 2026-09-15 | 2026-09-30 |
| Feasibility, Acceptability And Usability Of The InControl Web Platform - A Rando Mized Parallel-Group Pilot Study of Mixed-methods InControl intervention, Usual Care - Chronic Musculoskeletal Pain | Not applicable | Not yet recruiting | Aveiro University | 34 | 2026-09-01 | 2026-08-19 |
| Does Estrogen Blunt the Effects of Exercise Training on Glycemic Control EXERCISE TRAINING WITH OR WITHOUT MEDICATION - To Determine Whether Estrogen Influences the Effects of Training on Glycemic Control and Insulin Sensitivity | Not applicable | Not yet recruiting | University of Waterloo | 24 | 2026-08-01 | 2026-08-27 |
| Digitally Supported Short-Term Prehabilitation Before Total Knee Replacement EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Usual Care Group - Knee Osteoarthristis, Total Knee Replacement | Not applicable | Not yet recruiting | Ludwig Boltzmann Institute for Digital Health and Prevention | 60 | 2026-07-15 | 2026-07-14 |
| Clinical Decision Support to Increase Use of Medications for Opioid Use Disorder Medications for Opioid Use Disorder Pathway Clinical Decision Support (CDS) - Medication Abuse, Harm Reduction | Recruiting | University of Colorado, Denver | 200000 | 2026-07-07 | 2026-09-21 | |
| Active Airways for Children and Young People With Asthma EXERCISE TRAINING WITH OR WITHOUT MEDICATION, education - Asthma Childhood, Exercise | Not applicable | Not yet recruiting | University of Leicester | 60 | 2026-07-01 | 2026-06-11 |
| Microneedling for Androgenic Alopecia: a Clinical Study Microneedling monotherapy without drugs - Androgenic Alopecia | Not applicable | Active not recruiting | Taipei Medical University WanFang Hospital | 25 | 2026-06-01 | 2026-08-21 |
| Comparative Efficacy of Antibiotics for Small Intestine Bacterial Overgrowth in Bangladeshi Children Trimethoprim-sulfamethoxazole (TMP/SMX), Metronidazole, Amoxicillin-Clavulanate (4:1 formulation) - Small Intestine Bacterial Overgrowth | Phase 2 | Recruiting | University of Virginia | 60 | 2026-04-18 | 2026-08-18 |
| Efficacy and Safety Study of BPR-101 Capsules in Combination With Metronidazole in BV Patients BPR-101 capsules:Investigational product for the treatment of BV, Placebo：matching the investigational product in appearance, dosage form, and route of administration - Bacterial Vaginosis | Phase 2 | Not yet recruiting | Chengdu Syncor Pharmaceutical Co., Ltd. | 80 | 2026-04-15 | 2026-03-19 |
| What is the Role of Type III/IV Muscle Afferents in Airway Resistance and Thermoregulatory Responses to Exercise? EXERCISE TRAINING WITH OR WITHOUT MEDICATION - Placebo - Control, Experimental | Early Phase 1 | Not yet recruiting | Northern Arizona University | 15 | 2026-04-01 | 2026-03-05 |
| Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms Electroacupuncture (EA), Sham Electroacupuncture (SEA), Medication - Generalized Anxiety Disorder | Not applicable | Recruiting | Lishu Gao | 123 | 2026-03-10 | 2026-10-26 |
| Exergames in Mental Health EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Control - Mental Disorders | Not applicable | Completed | University of Salamanca | 12 | 2026-03-01 | 2026-05-20 |
| The Impact of Exercise on the Tumor Microenvironment in Patients With Lung Cancer EXERCISE TRAINING WITH OR WITHOUT MEDICATION - Lung Cancer - Non Small Cell | Not applicable | Recruiting | University of Arizona | 48 | 2026-01-13 | 2026-04-21 |
| Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis TNFi (Tumor Necrosis Factor inhibitor) medication, Abatacept, Tocilizumab - Polyarticular Course Juvenile Idiopathic Arthritis (JIA) | Phase 3 | Recruiting | Duke University | 400 | 2026-01-09 | 2026-10-21 |
| Exercise and Neuromodulation in Fibromyalgia EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Neuromodulators - Fibromyalgia (FM) | Not applicable | Not yet recruiting | Universidad Nacional Andres Bello | 40 | 2026-01-01 | 2026-01-07 |
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Motor Activity (11) · Opioid-Related Disorders (9) · Hypertension (8) · Obesity (8) · Depression (7) · Pain (7) · Cardiovascular Diseases (6) · Depressive Disorder, Major (5) · Renal Insufficiency, Chronic (5) · Schizophrenia (5) · Substance-Related Disorders (5) · Atrial Fibrillation (4) · COVID-19 (4) · Coronary Artery Disease (4) · Low Back Pain (4)
Genzyme, a Sanofi Company (7) · Cairo University (6) · Pfizer (6) · AstraZeneca (4) · Yale University (4) · Assiut University (3) · Johns Hopkins University (3) · NYU Langone Health (3) · Riphah International University (3) · Sanofi Pasteur, a Sanofi Company (3) · University Hospital of Ferrara (3) · University of Pennsylvania (3) · Alison Gustafson (2) · Aveiro University (2) · Beijing Anzhen Hospital (2)
United States (77) · China (21) · Germany (17) · Spain (14) · Italy (13) · United Kingdom (13) · Canada (9) · Egypt (9) · Belgium (7) · Brazil (7) · France (7) · Netherlands (7) · Taiwan (7) · Thailand (6) · Turkey (Türkiye) (6)
Alison Gustafson, PhD (2) · Elvira V Lang, MD (2) · Hom-Lay Wang, DDS,MSD,PhD (2) · Judith S Hochman, MD (2) · Ahmed Ramadan (1) · Aino L. Andersen, MSc (1) · Alan A Ryan, Ph.D. (1) · Alda S. Marques, PhD (1) · Amany Abdel Wahid, PhD (1) · Amber K Norris, MD (1) · Amy Mathews, M.D. (1)
PMID 10675425, PMID 11788217, PMID 11991214, PMID 12147179, PMID 12517460, PMID 12914662, PMID 13394341, PMID 15007010, PMID 15020531, PMID 15141377, PMID 15671433, PMID 16368303, PMID 16458167, PMID 16703394, PMID 16923752, PMID 16988070, PMID 17208034, PMID 17305763, PMID 17430682, PMID 17684085, PMID 18370439, PMID 18536865, PMID 18779447, PMID 19154625, PMID 19231324, PMID 19351944, PMID 19433695, PMID 19712795, PMID 19833255, PMID 19878986, PMID 20220183, PMID 20392703, PMID 20439832, PMID 20579539, PMID 20664386, PMID 21105792, PMID 21242060, PMID 21450596, PMID 21807825, PMID 21861950, PMID 21911339, PMID 21982660, PMID 22007073, PMID 22060947, PMID 22146510, PMID 22322081, PMID 22440499, PMID 22445463, PMID 22559260, PMID 22585697
2019 (3), 2008 (2), 2015 (2), R01DK126637 (2), 1RC1MH088341 (1), 2017 (1), 5UG1DA040316-05 (1), K01DA061975 (1), P20GM125507 (1), P30MH066386 (1), R01DA042751 (1), R01HD045786 (1), R01HD113733 (1), R01HL117983 (1), R01HL149888 (1)