208 completed, 34 unknown, 16 not yet recruiting, 13 recruiting. 200 Not applicable, 30 Phase 3, 25 Phase 2, 22 Phase 4, 11 Phase 1.
Follow Dentin Sensitivity: new trials by email Literature Review of Dentin Sensitivity trials Research Report on Dentin Sensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity Test Toothpaste, Regular Fluoride Toothpaste - Dentin Sensitivity | Not applicable | Recruiting | HALEON | 192 | 2026-10-19 | 2026-10-30 |
| A Clinical Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity Test Toothpaste, Regular Fluoride Toothpaste - Dentin Sensitivity | Not applicable | Not yet recruiting | HALEON | 192 | 2026-09-01 | 2026-09-03 |
| Modified Coronally Advanced Tunnel for Mandibular Lingual Root Coverage Modified Coronally Advanced Tunnel with Connective Tissue Graft - Gingival Recession, Mucogingival Deformity - Insufficient Keratinized Tissue | Not applicable | Enrolling by invitation | University of Pittsburgh | 20 | 2026-07-23 | 2026-07-29 |
| Evaluation of Different Non-Invasive Methods in the Treatment of Dentin Hypersensitivity Associated With Non-Carious Cervical Lesions: A Split-Mouth Clinical Study D Blue Diode Laser, ProSylc Bioactive Glass Powder - Non-Carious Cervical Lesions (NCCLs), Dentin Hypersensitivity | Not applicable | Not yet recruiting | Cukurova University | 30 | 2026-07-20 | 2026-06-15 |
| Effectiveness of Two Different Desensitizing Dental Varnishes Fluoride-containing varnish, Fluoride-free varnish - Dentin Hypersensitivity, Dentin Desensitizing Agents | Not applicable | Recruiting | Ivoclar Vivadent AG | 66 | 2026-07-13 | 2026-08-20 |
| A Clinical Trial to Evaluate the Effects of Larineco Remineralizing Gum on Oral Health, Breath Freshness, Tooth Sensitivity, and Gum Comfort Larineco Remineralizing Gum - Bad Breath, Tooth Sensitivity | Not applicable | Active not recruiting | Larine C Corporation | 40 | 2026-07-02 | 2026-07-09 |
| Comparative Efficacy of Different Dentin Occluding Toothpaste Technologies 8% arginine + Zinc toothpaste, 5% Calcium Sodium Phosphosilicate toothpaste, 8% arginine toothpaste - Dentinal Sensitivity, Dentinal Hypersensitivity | Phase 3 | Recruiting | Colgate Palmolive | 132 | 2026-06-29 | 2026-08-07 |
| Dentine Hypersensitivity Using Dentine Adhesive With Strontium-doped Bioactive Glass-Ceramic Strontium-doped bioactive glass-ceramic-filled dentine adhesive, Universal dentine adhesive - Dentine Hypersensitivity | Not applicable | Recruiting | The University of Hong Kong | 142 | 2026-06-16 | 2026-09-21 |
| Dipotassium Oxalate for Postoperative Sensitivity in NCCLs Dipotassium Oxalate Gel - Dentin Hypersensitivity, Post Operative Sensitivity Control | Not applicable | Not yet recruiting | Postgraduate Medical Institute, Lahore | 64 | 2026-06-01 | 2026-04-22 |
| Diode Laser Plus CPP-ACPF vs CPP-ACPF Alone for Dentin Hypersensitivity Diode laser photobiomodulation combined with CPP-ACPF varnish, CPP-ACPF varnish - Dentin Hypersensitivity, Tooth Hypersensitivity | Not applicable | Not yet recruiting | Cairo University | 70 | 2026-04-01 | 2026-03-04 |
| Efficacy of Dissolvable Mineral Loaded Starch Particles Strips in Providing Rapid Relief of Dentin Hypersensitivity: A Randomized Clinical Trial dissolvable mineral-loaded starch particle strips, Novamin containing toothpaste - Dentin Hypersensitivity | Phase 4 | Completed | Cairo University | 82 | 2026-03-10 | 2026-06-25 |
| Real-World Study of a Calcium Sodium Phosphosilicate Anti-Sensitivity Toothpaste for Dentin Hypersensitivity Relief Calcium sodium phosphosilicate (CSPS) Toothpaste - Dentin Sensitivity | Not applicable | Active not recruiting | HALEON | 500 | 2026-03-04 | 2026-07-21 |
| Comparison of Post-Operative Sensitivity of 5th Genaration Bonding Agent With 8th Generation Bonding Agent in Class1 Composite Restoration 5th generation bonding agent, 8th generation bonding agent - Dentin Sensitivity | Not applicable | Completed | Rehman Medical Institute - RMI | 64 | 2026-03-01 | 2026-10-07 |
| Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated. epidemiological - Dentin Hypersensitivity, Erosive Tooth Wear | Recruiting | Indiana University | 2500 | 2026-02-19 | 2026-05-05 | |
| Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations Vitrebond™ Pulp Protect Liner/Base, Vitrebond™ Plus (comparator) - Caries, Dental, Tooth Decay | Not applicable | Terminated | Solventum US LLC | 5 | 2026-02-17 | 2026-05-06 |
| A Clinical Study to Evaluate the Effectiveness of an Test Toothpaste for the Relief of Dentin Hypersensitivity in a Chinese Population Test toothpaste, Sodium fluoride toothpaste - Dentin Sensitivity | Not applicable | Completed | HALEON | 177 | 2026-01-16 | 2026-04-14 |
| Graphene-Reinforced CAD/CAM Restorations for MIH-Affected Molars in Adolescents: A Prospective Clinical Study Graphene-reinforced CAD/CAM polymer (G-CAM®) - Tooth Demineralization, Tooth Sensitivity | Not applicable | Not yet recruiting | Universitat Internacional de Catalunya | 30 | 2026-01-10 | 2026-01-09 |
| Effect of Bleaching Regimen With Different Activation Modes on Color Stability, Surface Roughness, Tooth Sensitivity and Patient Satisfaction 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with Laser Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with LED/Light Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) - Chemical Activation Only - Bleaching; Satisfactory, Bleaching Sensitivity | Not applicable | Enrolling by invitation | Tanta University | 45 | 2026-01-01 | 2026-06-29 |
| A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers Dentin Hypersensitivity | Recruiting | HALEON | 375 | 2025-12-16 | 2026-04-28 | |
| Efficacy of Lasers, Propolis-Based Agent, and Sham for Dentine Hypersensitivity Nd:YAG Laser Application, Diode Laser Application, Herbal Propolis-Based Dentin Barrier Agent - Dentine Hypersensitivity | Not applicable | Completed | Ondokuz Mayıs University | 140 | 2025-12-15 | 2026-06-15 |
Showing 20 of 287. Sign in to see all of them.
Hypersensitivity (23) · Tooth Discoloration (12) · Molar Hypomineralization (8) · Gingival Recession (7) · Dental Caries (5) · Pain (4) · Periodontal Diseases (4) · Patient Satisfaction (3) · Tooth Erosion (3) · Toothache (3) · Gingivitis (2) · Pain, Postoperative (2) · Tooth Demineralization (2) · Bites and Stings (1)
Stomatognathic Diseases (287) · Tooth Diseases (287) · Immune System Diseases (23) · Mouth Diseases (15) · Pathological Conditions, Signs and Symptoms (13) · Congenital Abnormalities (10) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (10) · Developmental Defects of Enamel (10) · Periodontal Diseases (10) · Signs and Symptoms (10) · Stomatognathic System Abnormalities (10) · Tooth Abnormalities (10) · Dental Enamel Hypomineralization (9) · Gingival Diseases (9) · Neurologic Manifestations (9)
Sodium Fluoride (17) · Tin Fluorides (16) · fluorophosphate (14) · Low-Level Light Therapy (13) · potassium nitrate (13) · Arginine (7) · Lasers, Semiconductor (6) · gluma desensitizer (6) · Fluorides (5) · Gluma (4) · Hydrogen Peroxide (4) · Lasers (4) · Propolis (4) · Toothpastes (4) · Bifluorid 12 (3)
GlaxoSmithKline (28) · HALEON (21) · Universidade Federal do Para (19) · Cairo University (17) · Procter and Gamble (11) · Universidade Federal Fluminense (8) · Colgate Palmolive (7) · University of Sao Paulo (7) · Dow University of Health Sciences (6) · Pakistan Institute of Medical Sciences (6) · University of Pavia (5) · Johnson & Johnson Consumer and Personal Products Worldwide (4) · University of Nove de Julho (4) · Al-Azhar University (3) · Federal University of Uberlandia (3)
United States (57) · Brazil (46) · Egypt (33) · Pakistan (19) · Turkey (Türkiye) (16) · Italy (14) · United Kingdom (14) · China (13) · Canada (7) · Spain (7) · Saudi Arabia (5) · Chile (3) · Germany (3) · India (3) · Jordan (2)
Andrea Scribante, Associate Professor (4) · Afsheen Mansoor, PhD (3) · Cecy M Silva, PhD (3) · Egle Milia, Prof (3) · Nehal Amir, BDS (3) · Robert W Gerlach, DDS, MPH (3) · Aline C Peixoto (2) · Bennett T Amaechi, BDS, MS, PhD (2) · Cecy M Silva (2) · Michael Lynch, DMD, PhD (2) · A. Ruya Yazici, Prof. (1)
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