Evaluation of Different Non-Invasive Methods in the Treatment of Dentin Hypersensitivity Associated With Non-Carious Cervical Lesions: A Split-Mouth Clinical Study

This split-mouth clinical study was designed to compare the clinical effectiveness of two different non-invasive approaches used in the treatment of dentin hypersensitivity associated with non-carious cervical lesions (NCCLs). Dentin hypersensitivity is a common clinical condition characterized by a short, sharp pain arising from exposed dentin in response to thermal, evaporative, tactile, osmotic, or chemical stimuli. Non-carious cervical lesions play a significant role in the development of dentin hypersensitivity by exposing dentin surfaces to the oral environment.

In this study, the effectiveness of D Blue diode laser application and ProSylc bioactive glass powder application in reducing dentin hypersensitivity will be evaluated. The split-mouth study design will allow each participant to serve as their own control, thereby minimizing interindividual variability. Eligible teeth will be allocated to different treatment groups according to the study protocol, and all interventions will be performed following standardized clinical procedures.

The level of dentin hypersensitivity will be assessed before treatment and at predetermined follow-up intervals using standardized clinical evaluation methods. Based on the collected data, the effects of both treatment modalities on dentin hypersensitivity will be compared, and changes over time will be analyzed. In addition, the clinical applicability and patient tolerance of the interventions will be evaluated.

The findings of this study are expected to contribute to the existing literature regarding the effectiveness of non-invasive treatment methods for dentin hypersensitivity associated with non-carious cervical lesions and to provide evidence-based guidance for clinicians in selecting appropriate treatment approaches.

• D Blue Diode Laser (Device), also known as Diode Laser: D Blue diode laser application for the treatment of dentin hypersensitivity associated with non-carious cervical lesions.
• ProSylc Bioactive Glass Powder (Device), also known as Bioactive Glass Powder: ProSylc bioactive glass powder application for the treatment of dentin hypersensitivity associated with non-carious cervical lesions.

Primary outcomes

• Change in Dentin Hypersensitivity [Baseline, immediately after treatment, 1 week, 1 month, and 3 months]: Dentin hypersensitivity will be assessed using a Visual Analog Scale (VAS) following standardized air stimulus application. The change in VAS scores from baseline to follow-up visits will be evaluated.

Sex: All, ages: 18 Years to 65 Years

Inclusion Criteria:

* Individuals aged between 18 and 65 years. Systemically healthy individuals. Individuals with dentin hypersensitivity. Presence of two permanent teeth with similar severity of dentin hypersensitivity in the same participant.

Participants who agree to participate in the study and sign the informed consent form

Exclusion Criteria:

* Presence of active caries in the study teeth. Presence of cervical restoration in the study teeth. Presence of pulpal pathology. History of desensitizing treatment within the last 3 months. Pregnancy. Presence of systemic disease. Use of analgesics within the last 48 hours.