123 completed, 83 unknown, 24 recruiting, 10 not yet recruiting. 178 Not applicable, 45 Phase 2, 32 Phase 1, 4 Phase 3, 2 Phase 4.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Use of Photobiomodulation for Pain and Healing in Cesarean Section Photobiomodulation (PBM), Placebo PBM, Standard Hospital Treatment - Post Partum, Cesarean Birth | Phase 2 | Not yet recruiting | University of Nove de Julho | 30 | 2026-09-01 | 2026-09-08 |
| Photobiomodulation Effects on Blood Pressure and Vascular Function in Treated Hypertensive Patients Vascular Photobiomodulation, Sham Photobiomodulation - Hypertension | Not applicable | Recruiting | University of Nove de Julho | 80 | 2026-09-01 | 2026-09-09 |
| The Use of Photobiomodulation in the Treatment of Spasticity After Stroke. Photobiomodulation Therapy, Placebo PBM, Standard Multidisciplinary Rehabilitation Program for Spasticity - Stroke, Spasticity | Phase 1 / Phase 2 | Recruiting | University of Nove de Julho | 42 | 2026-08-28 | 2026-09-01 |
| Effect of Photobiomodulation on Healing of Venous Leg Ulcers Photobiomodulation Therapy, Sham Photobiomodulation, Compression Therapy - Venous Leg Ulcer (VLU), Venous Hypertension Ulcers | Not applicable | Recruiting | University of Nove de Julho | 102 | 2026-08-03 | 2026-09-09 |
| Chronic Effects of Photobiomodulation With an LED Vest on Functional Capacity, Inflammatory Markers, and Muscle Perfusion in Children With Asthma Photobiomodulation, Exercise - Asthma (Diagnosis) | Not applicable | Not yet recruiting | University of Nove de Julho | 60 | 2026-07-30 | 2026-06-02 |
| Disclosing Agents as Photosensitizers in aPDT for Biofilm Control in Children Mechanical Prophylaxis, aPDT with Erythrosine, aPDT with GC TriPlaque ID Gel - Dental Plaque | Not applicable | Not yet recruiting | University of Nove de Julho | 72 | 2026-05-31 | 2026-04-20 |
| Effects of Physical Training in Patients With Advanced Heart Failure physical training - Insuficiência Cardíaca, Transplante Cardíaco | Not applicable | Not yet recruiting | University of Nove de Julho | 22 | 2026-05-30 | 2026-04-08 |
| Effects of Transcutaneous Photobiomodulation on Diabetic Foot Ulcers. PBM - Photobiomodulation, Placebo PBM, Standard Treatment - Diabetes Mellitus, Foot Ulcer | Phase 2 | Recruiting | University of Nove de Julho | 20 | 2026-05-12 | 2026-09-04 |
| Photobiomodulation on Pain Perception During the Insertion of the T 380 Copper Intrauterine Device (IUD) Photobiomodulation, Simulation of Photobiomodulation - Pain | Not applicable | Enrolling by invitation | University of Nove de Julho | 72 | 2026-03-30 | 2026-07-29 |
| Longitudinal Evaluation of Minimally Invasive Protocols for Dental Caries in Brazilian Schoolchildren Fluoride Varnish Application (Preventive Protocol), Fluoride Varnish for Active Enamel Lesions, Atraumatic Restorative Treatment (ART) Sealant - Dental Caries | Not applicable | Recruiting | University of Nove de Julho | 2500 | 2026-02-28 | 2026-05-15 |
| Efficacy of Aerobic Exercise Versus Therapeutic Exercises on Exercise-induced Hypoalgesia in Knee Osteoarthritis Aerobic Exercise, Therapeutic Exercise - Osteoarthritis of the Knee | Not applicable | Recruiting | University of Nove de Julho | 90 | 2026-02-20 | 2026-06-25 |
| Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre Photobiomodulation, Simulation of Photobiomodulation, Standard treatment protocol - Rhinoplasty, Edema | Not applicable | Recruiting | University of Nove de Julho | 60 | 2026-01-30 | 2026-03-24 |
| Er:YAG Laser Combined With Vaginal Estriol for Genitourinary Syndrome of Menopause Topical estrogen therapy based on estriol (E3), Active Er:YAG Laser, Sham Er:YAG laser (minimal fluence) - Genitourinary Syndrome of Menopause | Not applicable | Recruiting | University of Nove de Julho | 60 | 2025-12-10 | 2026-04-23 |
| Antimicrobial Photodynamic Therapy in the Endodontic Treatment of Anterior Primary Teeth With Pulp Necrosis Conventional Endodontic Treatment, Antimicrobial Photodynamic Therapy - Dental Pulp Necroses, Tooth, Nonvital | Not applicable | Completed | University of Nove de Julho | 7 | 2025-11-01 | 2026-09-16 |
| Efficacy of Combined Fractional Er:Glass and Thulium Lasers Versus Microneedling for Atrophic Acne Scars Microneedling, Fractionated Er:Glass Laser combined to Fractionated Thulium Laser - Acne Scars | Not applicable | Recruiting | University of Nove de Julho | 84 | 2025-10-16 | 2025-11-26 |
| Halitosis, Sleep and Mental Health in Bariatric Surgery Candidates Obesity, Bariatric Surgery Candidate | Not yet recruiting | University of Nove de Julho | 110 | 2025-10-01 | 2025-09-16 | |
| Home-Based Photobiomodulation Effects in the Postoperative Period of Distal Radius Fractures Open reduction and internal fixation (ORIF) with locked volar plate, Home exercises, Active photobiomodulation - Distal Radius Fracture | Not applicable | Recruiting | University of Nove de Julho | 42 | 2025-09-06 | 2026-09-29 |
| Effects of a Yoga Program on the Functionality of Individuals Therapeutic exercise, Yoga therapeutic exercise - Knee Osteoarthritis | Not applicable | Recruiting | University of Nove de Julho | 90 | 2025-08-01 | 2025-12-18 |
| Effect of Oculomotor Therapy in Individuals With Convergence Insufficiency Oculomotor therapy, No Treatment Added - Convergence Insufficiency | Not applicable | Not yet recruiting | University of Nove de Julho | 70 | 2025-08-01 | 2025-06-25 |
| Effects of Photobiomodulation With Superpulsed Laser and Dual Wavelengths in Children and Adolescents Active Photobiomodulation, Sham Photobiomodulation - Facial Pain, Headache | Not applicable | Not yet recruiting | University of Nove de Julho | 60 | 2025-07-01 | 2025-06-22 |
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Temporomandibular Joint Disorders (15) · Halitosis (14) · Motor Activity (13) · Pain (11) · Asthma (8) · Inflammation (8) · Low Back Pain (8) · Neck Pain (8) · Osteoarthritis, Knee (8) · Dental Caries (7) · Molar Hypomineralization (7) · Peripheral Arterial Disease (7) · Edema (6) · Periodontal Diseases (6) · Bronchiectasis (5)
Low-Level Light Therapy (67) · Exercise (14) · Control Groups (9) · Exercise Therapy (7) · Photochemotherapy (7) · Phototherapy (7) · Lasers (6) · 1-phenyl-3,3-dimethyltriazene (5) · Therapeutics (5) · Physical Therapy Modalities (4) · Rehabilitation (4) · Transcranial Direct Current Stimulation (4) · Electric Stimulation Therapy (3) · Exercise Test (3) · Musculoskeletal Manipulations (3)
Brazil (201) · Uruguay (4)
Raphael Dias, PhD (4) · Christiane Pavani, PhD (3) · Lara Motta, PhD (3) · Sandra K Bussadori (3) · Anna Carolina R Horliana, PhD (2) · Camila HL Godoy (2) · Cid Gomes, MSc (2) · Cid Gomes, PhD (2) · Cristiane M Franca, PhD (2) · Daniela Ap Biasotto-Gonzalez, Doctor (2) · Dirceu Costa, Doctor (2) · Ernesto Cesar P Leal-Junior, PhD, PT (2) · Ernesto Leal-Junior, PhD (2)
PMID 24942380, PMID 20602109, PMID 30985667, PMID 31027098, PMID 10556117, PMID 10796403, PMID 11049150, PMID 11072777, PMID 11168198, PMID 11176394, PMID 11276514, PMID 11553080, PMID 12498538, PMID 12513916, PMID 12601569, PMID 12824459, PMID 12931761, PMID 12956475, PMID 1443317, PMID 14485018, PMID 14689344, PMID 14706503, PMID 14709224, PMID 1494764, PMID 14972061, PMID 15015736, PMID 15145152, PMID 15214219, PMID 15315733, PMID 15332186, PMID 15617967, PMID 15626317, PMID 15882225, PMID 16144476, PMID 16145388, PMID 16251787, PMID 16310147, PMID 16982941, PMID 17053104, PMID 17089179, PMID 17133529, PMID 17199474, PMID 17228207, PMID 17382159, PMID 17450530, PMID 17803384, PMID 17981047, PMID 17982558, PMID 17983611, PMID 18158033
2014 (1)