34 completed, 10 unknown, 3 not yet recruiting, 1 active not recruiting. 25 Not applicable, 9 Phase 2, 9 Phase 3, 3 Early Phase 1, 3 Phase 1.
Follow Propolis: new trials by email Literature Review of Propolis trials Research Report on Propolis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of a Herbal Intracanal Medication On Postoperative Pain And Flare up Incidence In Non Surgical Root Canal Retreatment Calcium hydroxide, Propolis Extract, Green Tea Polyphenolics (EGCG) - Postoperative Pain, Flare Up, Symptom | Not applicable | Not yet recruiting | Minia University | 40 | 2026-07-01 | 2026-05-11 |
| Effects of Royal Jelly and Propolis on Metabolomic Signatures, Inflammation, and Cardiovascular Risk in Patients With Coronary Artery Disease. Propolis + Royal Jelly, Placebo - Coronary Artery Disease (CAD), Oxidative Stress | Not applicable | Not yet recruiting | Universidade Federal Fluminense | 50 | 2026-05-18 | 2026-05-19 |
| Dermocosmetic Evaluation of Propolis Ointments in Atopic-Prone Dry Skin Ethanolic extract of propolis, Crude propolis, Vehicle ointment - Dry Skin, Atopic Dermatitis | Not applicable | Completed | Manara University | 30 | 2026-04-15 | 2026-10-08 |
| Propolis-Based Solution Application in Extraction Socket Healing Propolis-based topical solution (52% propolis extract, clove oil [Eugenia caryophyllus], and white willow bark [Salix alba] extract), Saline rinse (control) - Healthy | Phase 1 / Phase 2 | Completed | Saint-Joseph University | 14 | 2025-10-01 | 2026-06-29 |
| Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients propolis, chlorohexidine mouthwash and topical antifungal - Oral Mucositis Due to Chemotherapy | Phase 2 | Not yet recruiting | Ain Shams University | 50 | 2025-07-15 | 2025-07-18 |
| Propolis Lozenges Extract and Their Effect on Salivary Biomarkers and on Oral Health Condition in (19_24) Years Old lozenges containing propolis - Plaque Induced Gingivitis, Mouth Diseases | Phase 1 | Completed | Al-Mustansiriyah University | 100 | 2025-03-23 | 2025-09-24 |
| Antibacterial Effect of Ozonated Olive Oil, Propolis and Chlorhexidine Mouthwashes in Pediatric Patients Ozonated olive oil, Propolis, Chlorhexidine - Oral Hygiene, Oral Health | Not applicable | Completed | Alexandria University | 51 | 2025-02-25 | 2025-09-29 |
| The Effect of Oral Care With Propolis in COPD Patients Oral care with propolis - Oral Mucositis | Not applicable | Completed | TC Erciyes University | 60 | 2025-01-01 | 2026-02-23 |
| Evaluation of the Effectiveness of Home-Use Desensitizing Agents on Dentin Hypersensitivity Control group, Arginine, Novamin - Dentin Sensitivity | Not applicable | Completed | Çanakkale Onsekiz Mart University | 180 | 2024-03-01 | 2024-08-26 |
| An Investigation of the Effects of a Skin Serum Containing Propolis on Skin Health and Appearance Manuka Health Pro Vitality Daily Restorative Face Serum with Propolis & Vitamin C - Skin Health | Not applicable | Completed | Manuka Health | 40 | 2023-11-09 | 2024-11-20 |
| Role of Propolis Endodontic Irrigant on Post-Operative Pain Sodium hypochlorite 5.25%, Propolis 20% - Post-operative Pain, Symptomatic Irreversible Pulpitis | Phase 3 | Completed | Dow University of Health Sciences | 44 | 2023-04-01 | 2023-09-07 |
| Effects for Oral Mucositis Care During Chemoradiotherapy in Cancer Patients: Evaluation of the Bee Products Honey product, propolis, Usual care - Oral Mucositis | Not applicable | Unknown | Taipei Medical University | 135 | 2022-11-25 | 2022-11-23 |
| Effect of Propolis Administration for Dysmenorrhea in Endometriosis Patient With Levonorgestrel Implant Therapy Propolis, placebo - Endometriosis, Dysmenorrhea | Not applicable | Unknown | Universitas Indonesia | 24 | 2022-07-12 | 2023-06-06 |
| Oral Care With Propolis in Pediatric Oncology Patients propolis, Placebo - Oral Mucositis | Not applicable | Completed | Izmir Katip Celebi University | 108 | 2022-06-01 | 2023-09-29 |
| Effects of Microencapsulated Propolis and Turmeric in Patients With Chronic Kidney Disease Microcapsules with turmeric and propolis - Chronic Kidney Diseases, Inflammation | Not applicable | Active not recruiting | Universidade Federal Fluminense | 34 | 2022-03-07 | 2025-04-03 |
| Effect of Hyaluronic Acid Oral Supplementation on Sexual and Urinary Symptoms of Women With Recurrent Urinary Tract Infections HA 100 mg, CS 400 mg, N-Acetylglucosamine 200 mg and vitamin C 80 mg + cranberry, D-mannose, propolis extract, tumeric and Boswellia, cranberry, D-mannose, propolis extract, tumeric and Boswellia - Urinary Tract Infections, Recurrent | Not applicable | Completed | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 50 | 2022-03-01 | 2024-02-20 |
| Combination of Diclofenac Potassium and Propolis in the Therapy of Oral Aphthosis Combination of diclofenac potassium and propolis, placebo - Oral Mucositis, ORAS | Early Phase 1 | Completed | Al-Azhar University | 100 | 2021-06-01 | 2023-07-21 |
| Investigation of Clinical Effectiveness of Propolis Extracts as Food Supplements in Patients With SARS-CoV-2(COVID-19) propolis - SARS-CoV2 Infection | Not applicable | Unknown | Trabzon Kanuni Education and Research Hospital | 45 | 2021-05-15 | 2021-06-08 |
| Efficacy of Desensitizing Agent,Propolis After an In-office Vital Tooth Bleaching. Propolis, hydrogen peroxide 35%, fluoride varnish - Post Operative Pain | Not applicable | Completed | Dow University of Health Sciences | 90 | 2021-05-14 | 2022-10-06 |
| Brazilian Green Propolis Extract (EPP-AF) as an Adjunct Treatment for Hospitalized COVID-19 Patients (BeeCovid2) Standardized Brazilian Green Propolis Extract, Placebo - Covid19, Inflammation | Phase 2 / Phase 3 | Completed | D'Or Institute for Research and Education | 200 | 2021-04-12 | 2022-05-13 |
Showing 20 of 48. Sign in to see all of them.
Pain, Postoperative (6) · Stomatitis (6) · Inflammation (5) · Dentin Sensitivity (4) · Dental Caries (3) · Mucositis (3) · Renal Insufficiency, Chronic (3) · COVID-19 (2) · Chronic Periodontitis (2) · Dental Pulp Necrosis (2) · Endometriosis (2) · Gingivitis (2) · Head and Neck Neoplasms (2) · Mouth Diseases (2) · Periodontal Diseases (2)
Cairo University (4) · Dow University of Health Sciences (4) · Taipei Medical University (3) · Universidade Federal Fluminense (3) · Al-Azhar University (2) · Universitas Indonesia (2) · Ain Shams University (1) · Aix Marseille Université (1) · Al-Mustansiriyah University (1) · Alexandria University (1) · Cindy Elizabeth de Lira-Quezada (1) · D'Or Institute for Research and Education (1) · Dr. Santiago Palacios (1) · Federal University of Minas Gerais (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1)
Brazil (7) · Egypt (7) · Pakistan (5) · Turkey (Türkiye) (5) · Indonesia (2) · Mexico (2) · Taiwan (2) · United States (2) · France (1) · India (1) · Iran (1) · Iraq (1) · Italy (1) · Lebanon (1) · Spain (1)
Denise Mafra, phd (2) · Tsai-Wei Huang, PhD (2) · Ather Akber, M.Sc (1) · Dwirini Retno Gunarti, Dr drg Master of Science (1) · Erica N Lia, PhD (1) · Farah Naz, BDS FCPS (1) · Fatima Soomro, MDS (1) · Fazal R Qazi (1) · Gisela M Pina, DDS (1) · Haya Farhat, BPharm St. (1) · Hesham M. El-Sharkawy, Ass.Prof. (1) · Jean Francois Landrier, PhD (1) · Juzer S Saifee (1)
PMID 15660575, PMID 16161031, PMID 17167116, PMID 18696746, PMID 21965377, PMID 23320022, PMID 25607548, PMID 26916845, PMID 31023272, PMID 35379306, PMID 36708650, PMID 36934668, PMID 37023336, PMID 37891178, PMID 37916745, PMID 38721680, PMID 38783427, PMID 39453192, PMID 39810073, PMID 40296308, PMID 40424080