144 completed, 21 unknown, 14 not yet recruiting, 8 recruiting. 201 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 201 | Completed 144, Unknown 21, Not yet recruiting 14, Recruiting 8, Active not recruiting 7, Enrolling by invitation 4, Terminated 3 |
Follow Dentin Sensitivity: new trials by email Literature Review of Dentin Sensitivity trials Research Report on Dentin Sensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Different Adhesive Removal Techniques After Orthodontic Bracket Debonding on Postoperative Hypersensitivity: A Randomized Clinical Trial Low-Speed Tungsten Carbide Bur, Fiberglass Bur, White Stone Bur - Dentin Sensitivity, Orthodontic Adhesive Removal | Not applicable | Not yet recruiting | Asmaa Badr Abdelfatah | 15 | 2026-11-01 | 2026-11-13 |
| A Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity Test Toothpaste, Regular Fluoride Toothpaste - Dentin Sensitivity | Not applicable | Recruiting | HALEON | 192 | 2026-10-19 | 2026-10-30 |
| A Clinical Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity Test Toothpaste, Regular Fluoride Toothpaste - Dentin Sensitivity | Not applicable | Not yet recruiting | HALEON | 192 | 2026-09-01 | 2026-09-03 |
| Modified Coronally Advanced Tunnel for Mandibular Lingual Root Coverage Modified Coronally Advanced Tunnel with Connective Tissue Graft - Gingival Recession, Mucogingival Deformity - Insufficient Keratinized Tissue | Not applicable | Enrolling by invitation | University of Pittsburgh | 20 | 2026-07-23 | 2026-07-29 |
| Evaluation of Different Non-Invasive Methods in the Treatment of Dentin Hypersensitivity Associated With Non-Carious Cervical Lesions: A Split-Mouth Clinical Study D Blue Diode Laser, ProSylc Bioactive Glass Powder - Non-Carious Cervical Lesions (NCCLs), Dentin Hypersensitivity | Not applicable | Not yet recruiting | Cukurova University | 30 | 2026-07-20 | 2026-06-15 |
| Effectiveness of Two Different Desensitizing Dental Varnishes Fluoride-containing varnish, Fluoride-free varnish - Dentin Hypersensitivity, Dentin Desensitizing Agents | Not applicable | Recruiting | Ivoclar Vivadent AG | 66 | 2026-07-13 | 2026-08-20 |
| A Clinical Trial to Evaluate the Effects of Larineco Remineralizing Gum on Oral Health, Breath Freshness, Tooth Sensitivity, and Gum Comfort Larineco Remineralizing Gum - Bad Breath, Tooth Sensitivity | Not applicable | Active not recruiting | Larine C Corporation | 40 | 2026-07-02 | 2026-07-09 |
| Dentine Hypersensitivity Using Dentine Adhesive With Strontium-doped Bioactive Glass-Ceramic Strontium-doped bioactive glass-ceramic-filled dentine adhesive, Universal dentine adhesive - Dentine Hypersensitivity | Not applicable | Recruiting | The University of Hong Kong | 142 | 2026-06-16 | 2026-09-21 |
| Dipotassium Oxalate for Postoperative Sensitivity in NCCLs Dipotassium Oxalate Gel - Dentin Hypersensitivity, Post Operative Sensitivity Control | Not applicable | Not yet recruiting | Postgraduate Medical Institute, Lahore | 64 | 2026-06-01 | 2026-04-22 |
| Diode Laser Plus CPP-ACPF vs CPP-ACPF Alone for Dentin Hypersensitivity Diode laser photobiomodulation combined with CPP-ACPF varnish, CPP-ACPF varnish - Dentin Hypersensitivity, Tooth Hypersensitivity | Not applicable | Not yet recruiting | Cairo University | 70 | 2026-04-01 | 2026-03-04 |
| Real-World Study of a Calcium Sodium Phosphosilicate Anti-Sensitivity Toothpaste for Dentin Hypersensitivity Relief Calcium sodium phosphosilicate (CSPS) Toothpaste - Dentin Sensitivity | Not applicable | Active not recruiting | HALEON | 500 | 2026-03-04 | 2026-07-21 |
| Comparison of Post-Operative Sensitivity of 5th Genaration Bonding Agent With 8th Generation Bonding Agent in Class1 Composite Restoration 5th generation bonding agent, 8th generation bonding agent - Dentin Sensitivity | Not applicable | Completed | Rehman Medical Institute - RMI | 64 | 2026-03-01 | 2026-10-07 |
| Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations Vitrebond™ Pulp Protect Liner/Base, Vitrebond™ Plus (comparator) - Caries, Dental, Tooth Decay | Not applicable | Terminated | Solventum US LLC | 5 | 2026-02-17 | 2026-05-06 |
| A Clinical Study to Evaluate the Effectiveness of an Test Toothpaste for the Relief of Dentin Hypersensitivity in a Chinese Population Test toothpaste, Sodium fluoride toothpaste - Dentin Sensitivity | Not applicable | Completed | HALEON | 177 | 2026-01-16 | 2026-04-14 |
| Graphene-Reinforced CAD/CAM Restorations for MIH-Affected Molars in Adolescents: A Prospective Clinical Study Graphene-reinforced CAD/CAM polymer (G-CAM®) - Tooth Demineralization, Tooth Sensitivity | Not applicable | Not yet recruiting | Universitat Internacional de Catalunya | 30 | 2026-01-10 | 2026-01-09 |
| Effect of Bleaching Regimen With Different Activation Modes on Color Stability, Surface Roughness, Tooth Sensitivity and Patient Satisfaction 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with Laser Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with LED/Light Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) - Chemical Activation Only - Bleaching; Satisfactory, Bleaching Sensitivity | Not applicable | Enrolling by invitation | Tanta University | 45 | 2026-01-01 | 2026-06-29 |
| Efficacy of Lasers, Propolis-Based Agent, and Sham for Dentine Hypersensitivity Nd:YAG Laser Application, Diode Laser Application, Herbal Propolis-Based Dentin Barrier Agent - Dentine Hypersensitivity | Not applicable | Completed | Ondokuz Mayıs University | 140 | 2025-12-15 | 2026-06-15 |
| A Study to Investigate the Tooth Whitening and Dentin Hypersensitivity Effectiveness of Two Experimental Toothpastes Test Toothpaste 1, Test Toothpaste 2, Reference Toothpaste - Dentin Hypersensitivity | Not applicable | Completed | HALEON | 254 | 2025-12-15 | 2026-03-31 |
| Effect of Fluoride Varnish Formulation on the Management of Dentin Hypersensitivity Aqueous fluoride varnish, 9,500 ppm NaF, Resin/rosin-based varnish, 22,600 ppm NaF - Hypersensitivity Dentin, Fluoride Varnishes | Not applicable | Recruiting | University of Concepcion, Chile | 92 | 2025-12-04 | 2026-06-02 |
| Laser Therapy for Dentin Hypersensitivity Er,Cr;YSGG Laser, Waterlase, Biolase Technology Inc., Irvine, CA, ABD, Remin Pro (VOCO, Cuxhaven, Germany) - Dentin Hypersensitivity | Not applicable | Completed | Hacettepe University | 25 | 2025-11-11 | 2026-10-21 |
Showing 20 of 201. Sign in to see all of them.
Hypersensitivity (17) · Tooth Discoloration (12) · Molar Hypomineralization (7) · Gingival Recession (6) · Dental Caries (4) · Pain (3) · Patient Satisfaction (3) · Pain, Postoperative (2) · Periodontal Diseases (2) · Tooth Demineralization (2) · Tooth Erosion (2) · Celiac Disease (1) · Chronic Periodontitis (1) · Dental Calculus (1)
Stomatognathic Diseases (201) · Tooth Diseases (201) · Immune System Diseases (17) · Mouth Diseases (11) · Pathological Conditions, Signs and Symptoms (10) · Congenital Abnormalities (9) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (9) · Developmental Defects of Enamel (9) · Stomatognathic System Abnormalities (9) · Tooth Abnormalities (9) · Dental Enamel Hypomineralization (8) · Periodontal Diseases (8) · Gingival Diseases (7) · Signs and Symptoms (7) · Neurologic Manifestations (6)
Low-Level Light Therapy (10) · Tin Fluorides (7) · fluorophosphate (7) · Lasers, Semiconductor (5) · Sodium Fluoride (5) · gluma desensitizer (5) · Lasers (4) · Arginine (3) · Toothpastes (3) · Chewing Gum (2) · Control Groups (2) · Fluorides (2) · Gluma (2) · Laser Therapy (2) · Propolis (2)
HALEON (18) · Universidade Federal do Para (14) · GlaxoSmithKline (13) · Cairo University (11) · Procter and Gamble (10) · Universidade Federal Fluminense (8) · Pakistan Institute of Medical Sciences (6) · University of Pavia (5) · Johnson & Johnson Consumer and Personal Products Worldwide (4) · Federal University of Uberlandia (3) · University of Sao Paulo (3) · Al-Azhar University (2) · Dentsply International (2) · Dow University of Health Sciences (2) · Faculty of Dental Medicine for Girls (2)
United States (39) · Brazil (31) · Egypt (25) · Turkey (Türkiye) (16) · United Kingdom (13) · Italy (12) · Pakistan (11) · China (9) · Spain (5) · Saudi Arabia (4) · Canada (2) · Germany (2) · India (2) · Jordan (2) · Vietnam (2)
Andrea Scribante, Associate Professor (4) · Afsheen Mansoor, PhD (3) · Cecy M Silva, PhD (3) · Nehal Amir, BDS (3) · Robert W Gerlach, DDS, MPH (3) · Cecy M Silva (2) · Egle Milia, Prof (2) · Michael Lynch, DMD, PhD (2) · A. Ruya Yazici, Prof. (1)
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