21 completed, 1 unknown. 22 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 22 | Completed 21, Unknown 1 |
Follow Dentin Sensitivity: new trials by email Literature Review of Dentin Sensitivity trials Research Report on Dentin Sensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Dissolvable Mineral Loaded Starch Particles Strips in Providing Rapid Relief of Dentin Hypersensitivity: A Randomized Clinical Trial dissolvable mineral-loaded starch particle strips, Novamin containing toothpaste - Dentin Hypersensitivity | Phase 4 | Completed | Cairo University | 82 | 2026-03-10 | 2026-06-25 |
| A Clinical Study Assessing the Effects of a Marketed Dentifrice on Tooth Sensitivity While Undergoing Tooth Bleaching Test Dentifrice (Sensodyne Repair and Protect Original Mint), Positive Control Dentifrice (Sensodyne Fresh Mint), Reference Dentifrice (Crest Cavity Protection Regular) - Dentin Sensitivity | Phase 4 | Completed | HALEON | 90 | 2024-10-07 | 2025-12-15 |
| Postoperative Sensitivity Following Placement with Different Restorative Materials in Vital Posterior Teeth Tetric N Bond Universal®, Self Etch Tetric N Bond Universal®, GC Fuji IX, GC, Japan® - Sensitivity, Tooth | Phase 4 | Completed | Liaquat University of Medical & Health Sciences | 160 | 2023-06-01 | 2025-03-06 |
| Toothpastes With Thermal Water for Oral Health BUCCOTHERM® Sensitive Gums with Fluoride, BUCCOTHERM® Sensitive Gums Fluoride-Free - Gingivitis, Dentin Hypersensitivity | Phase 4 | Completed | I.M. Sechenov First Moscow State Medical University | 84 | 2022-11-01 | 2023-03-01 |
| Efficacy of a Sonic Toothbrush and 8% Arginine Toothpaste in Reducing Dentinal Hypersensitivity 8.0% Arginine Dentifrice, Electric Sonic Toothbrush, Adult Soft Bristle Manual Toothbrush - Dentin Sensitivity, Dentin Hypersensitivity | Phase 4 | Completed | Colgate Palmolive | 80 | 2021-12-06 | 2026-10-16 |
| Effect of Different Desensitizing Agents on Post-bleaching Hypersensitivity and Shade Stability Potassium nitrate with fluoride, Casein phosphopeptide-amorphous calcium phosphate with fluoride, Hydroxyapatite with fluoride - Tooth Hypersensitivity | Phase 4 | Completed | Ain Shams University | 48 | 2021-11-13 | 2024-04-23 |
| A Clinical Study for the Effect of 4th Generation Poly AmidoAmine Dendrimer on Post-Bleaching Hypersensitivity and Shade Stability Poly amido amine dendrimer (PAMAM), Manufacturer's desensitizing agent, Ultra EZ, MI paste plus, desensitizing agent - Tooth Hypersensitivity | Phase 4 | Completed | Ain Shams University | 60 | 2021-11-13 | 2024-04-23 |
| Ca-hydroxyapatite, Fluoroapatite, and Mg-Zn-hydroxyapatite for Dentin Hypersensitivity Management Hygienic procedure (toothbrushing using HAP-containing toothpaste), Hygienic procedure (toothbrushing using Zn Mg HAP-containing), Hygienic procedure (toothbrushing using FAP-containing toothpaste) - Dentin Hypersensitivity | Phase 4 | Completed | I.M. Sechenov First Moscow State Medical University | 30 | 2021-04-24 | 2021-10-01 |
| Comparative Study on the Efficacy of OliNano SEAL and Curodont D' Senz in Treatment of Dentin Hypersensitivity Olinanoseal, Curodont D'senz - Dentin Hypersensitivity | Phase 4 | Completed | Al-Azhar University | 70 | 2020-04-20 | 2021-11-16 |
| Comparative Clinical Evaluation of Three Different Agents in Reducing Dental Hypersensitivity in Periodontal Patients Sensodyne Repair and Protect, Dentalclean Daily Regenerator, Dentalclean Daily Regenerator with potassium citrate - Dentin Hypersensitivity, Periodontal Diseases | Phase 4 | Completed | University of Sao Paulo | 33 | 2019-07-29 | 2023-11-28 |
| the Efficacy of Giomer Versus Sodium Fluoride in the Treatment of Hypersensitivity shofu PRG barrier coat, Sodium fluoride varnish - Tooth Hypersensitivity | Phase 4 | Unknown | Cairo University | 104 | 2019-03-01 | 2019-01-28 |
| To Investigate the Efficacy of an Occluding Dentifrice in Dentinal Hypersensitivity (DH) Stannous fluoride, Sodium monofluorophosphate - Dentin Sensitivity | Phase 4 | Completed | GlaxoSmithKline | 197 | 2016-10-11 | 2018-10-29 |
| Effectiveness of Nanohydroxyapetite Paste on Reducing Dentin Hypersensitivity 5% Sodium Fluoride Varnish, 15% Nanohydroxyapetite paste, Glycerol - Dentin Hypersensitivity | Phase 4 | Completed | Riyadh Colleges of Dentistry and Pharmacy | 63 | 2016-10-01 | 2020-03-11 |
| Combined Bleaching Technique: Efficacy and Tooth Sensitivity Combined Bleaching(2x20), Combined Bleaching(2x20) with arginine, Combined Bleaching (1x20) - Tooth Bleaching, Tooth Sensitivity | Phase 4 | Completed | Terezinha de Jesus Esteves Barata | 108 | 2016-04-01 | 2019-08-05 |
| Short Term Clinical Study Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity stannous fluoride, sodium monofluorophosphate - Dentin Sensitivity | Phase 4 | Completed | GlaxoSmithKline | 229 | 2016-04-01 | 2017-05-17 |
| Nano-hydroxyapatite With Potassium Nitrate in the Therapy of the Dental Sensitivity Cavex Bite&White ExSense, Colgate, Protection Caries, Placebo gel - Dentin Sensitivity | Phase 4 | Completed | Università degli Studi di Sassari | 35 | 2016-03-01 | 2016-10-26 |
| Study to Investigate the Efficacy of an Occluding Dentifrice in Providing Relief From Dentine Hypersensitivity Stannous Fluoride Dentifrice, Sodium monofluorophosphate Dentifrice - Dentin Sensitivity | Phase 4 | Completed | GlaxoSmithKline | 143 | 2016-01-01 | 2017-09-29 |
| Efficacy of Two Oral Hygiene Regimens in the Reduction of Dentin Hypersensitivity After Periodontal Treatment In-office and at home Colgate sensitive pro-relief - CSPR, In-office Villevie® prophy paste + Colgate Toothpaste, Non-surgical periodontal treatment - Dentin Sensitivity, Periodontal Diseases | Phase 4 | Completed | University of Campinas, Brazil | 60 | 2014-08-01 | 2015-06-03 |
| Clinical Study of the Whitening Dentifrices on Tooth Color and Sensitivity whitening dentifrices, Placebo - Dentin Hypersensitivity | Phase 4 | Completed | University of Sao Paulo | 60 | 2014-08-01 | 2015-06-26 |
| Longevity and Effectiveness of Bleaching in Healthy and Smokers Patients Peroxide Carbamide 10% - Dental bleaching treatment - Dentin Sensitivity | Phase 4 | Completed | University of Chile | 120 | 2013-12-01 | 2015-05-27 |
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Periodontal Diseases (2) · Bites and Stings (1) · Gingivitis (1) · Hypersensitivity (1) · Pain (1) · Tooth Abrasion (1) · Toothache (1)
Stomatognathic Diseases (22) · Tooth Diseases (22) · Mouth Diseases (3) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Chemically-Induced Disorders (1) · Facial Pain (1) · Gingival Diseases (1) · Immune System Diseases (1) · Infections (1) · Pain (1) · Periodontal Diseases (1) · Poisoning (1) · Tooth Wear (1)
Durapatite (2) · Fluorides (2) · Tin Fluorides (2) · fluorophosphate (2) · Arginine (1) · Bifluorid 12 (1) · Calcium Carbonate (1) · Carbamide Peroxide (1) · Dentifrices (1) · Glycerol (1) · Potassium Citrate (1) · Sodium Fluoride (1) · hydrated silica gel-based toothpaste (1) · potassium nitrate (1) · sodium fluoride topical preparation (1)
GlaxoSmithKline (4) · University of Sao Paulo (3) · Ain Shams University (2) · Cairo University (2) · I.M. Sechenov First Moscow State Medical University (2) · Al-Azhar University (1) · Colgate Palmolive (1) · HALEON (1) · Liaquat University of Medical & Health Sciences (1) · Riyadh Colleges of Dentistry and Pharmacy (1) · Terezinha de Jesus Esteves Barata (1) · University of Campinas, Brazil (1) · University of Chile (1) · Università degli Studi di Sassari (1)
Brazil (6) · Egypt (5) · Canada (4) · Russia (2) · Chile (1) · Italy (1) · Pakistan (1) · Saudi Arabia (1) · United States (1)
Camila Tirapeli, PhD (1) · Camila Tirapelli, PhD (1) · Dalia N AlHarith (1) · Eduardo Fernandez, Prof. (1) · Egle Milia, Prof (1) · Enilson A Sallum, PhD (1) · Farid MS Al Askary, Professor (1) · Farid MS El-Askary, Professor (1) · Irina M Makeeva (1) · Maria Polyakova, PhD (1) · Mariana S Ragghianti Zangrando, Prof (1) · Priya Rani, BDS (1)