24 completed, 5 unknown, 3 recruiting, 2 not yet recruiting. 14 Phase 2, 12 Not applicable, 4 Phase 1, 4 Phase 3, 1 Phase 4.
Follow potassium nitrate: new trials by email Literature Review of potassium nitrate trials Research Report on potassium nitrate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of an Experimental Cannabidiol Gel on Tooth Sensitivity Potassium nitrate and sodium fluoride, Cannabidiol (CBD) Gel, Natrosol 4% Gel - Dentin Sensitivity | Phase 1 | Not yet recruiting | Universidade Federal do Para | 75 | 2025-07-25 | 2025-06-18 |
| Clinical and Radiographic Evaluation of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate in Vital Pulpotomy in Primary Molars Potassium Nitrate in Polycarboxylate cement, MTA-Anglus - Vital Pulp Therapies, Pulpotomy | Not applicable | Not yet recruiting | Cairo University | 50 | 2025-05-30 | 2025-03-12 |
| Bioadhesive Film of Acmella Oleracea (Jambu) in the Reduction of Post-bleaching Dental Sensitivity Caused by Bleaching With 35% Hydrogen Peroxide. Bioadhesive film of Acmella Oleracea (jambu), Gel containing 5% potassium nitrate and 2% sodium fluoride., Spilanthol-free bioadhesive bioplastic film - Tooth Sensitivity, Teeth Whitening | Phase 3 | Completed | Universidade Federal do Para | 72 | 2024-04-01 | 2026-03-17 |
| Evaluation of the Effectiveness of Home-Use Desensitizing Agents on Dentin Hypersensitivity Control group, Arginine, Novamin - Dentin Sensitivity | Not applicable | Completed | Çanakkale Onsekiz Mart University | 180 | 2024-03-01 | 2024-08-26 |
| Pregabalin Gel in Reducing Post-operative Tooth Sensitivity Surgery Caused by Bleaching With 35% Hydrogen Peroxide pregabalin gel, gel with 5% potassium nitrate and 2% sodium fluoride, Placebo gel - Tooth Bleaching, Sensitivity, Tooth | Phase 3 | Unknown | Universidade Federal do Para | 75 | 2024-01-05 | 2023-12-22 |
| Inulin and Nitrate's Effects on Vascular Health and Gut Microbiome Inulin, Potassium nitrate and inulin - Endothelial Dysfunction, High Blood Pressure | Not applicable | Completed | University of Exeter | 22 | 2023-05-09 | 2025-01-09 |
| The Inorganic Nitrate and eXercise Performance in Heart Failure (iNIX-HF) KNO3, Placebo - Heart Failure | Phase 2 | Recruiting | Washington University School of Medicine | 75 | 2023-03-31 | 2026-05-06 |
| The Impact of Inorganic Nitrate-rich Beetroot Juice on Microvascular Blood Flow and Cognitive Function Concentrated beetroot juice, Nitrate depleted beetroot juice + potassium nitrate (KNO3), Nitrate depleted beetroot juice - Post Menopausal | Not applicable | Completed | University of Reading | 20 | 2023-03-14 | 2024-11-22 |
| Potassium Nitrate in Polycarboxylate as a Direct Pulp Capping potassium nitrate in polycarboxilate cement - Pulp Disease, Dental | Not applicable | Unknown | Minia University | 126 | 2022-06-01 | 2023-06-22 |
| SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial Empagliflozin + Potassium Chloride, Empagliflozin + Potassium Nitrate, Potassium Chloride + Placebo for Empagliflozin - Heart Failure With Preserved Ejection Fraction | Phase 2 | Recruiting | University of Pennsylvania | 53 | 2022-01-24 | 2026-04-16 |
| Effect of Different Desensitizing Agents on Post-bleaching Hypersensitivity and Shade Stability Potassium nitrate with fluoride, Casein phosphopeptide-amorphous calcium phosphate with fluoride, Hydroxyapatite with fluoride - Tooth Hypersensitivity | Phase 4 | Completed | Ain Shams University | 48 | 2021-11-13 | 2024-04-23 |
| Matching Perfusion and Metabolic Activity in HFpEF Potassium Nitrate, Potassium Nitrate + Propionyl-L-Carnitine + Nicotinamide Riboside, Potassium Chloride - Heart Failure With Preserved Ejection Fraction | Phase 2 | Recruiting | University of Pennsylvania | 53 | 2021-10-11 | 2026-06-02 |
| Nitrate and Brain Insulin-Sensitivity Potassium nitrate, Placebo - Nitrate, Brain Insulin-sensitivity | Not applicable | Completed | Maastricht University Medical Center | 18 | 2021-01-21 | 2021-06-09 |
| Study to Characterize the Efficacy of a Dual Active Dentifrice for the Relief of Dentin Hypersensitivity Potassium Nitrate, Stannous Fluoride - Dentin Hypersensitivity, Dentin Sensitivity | Phase 2 | Completed | GlaxoSmithKline | 123 | 2019-05-13 | 2020-09-11 |
| The Use of Inorganic Nitrate for the Prevention of Contrast-induced Nephropathy Potassium Nitrate, Potassium Chloride - Contrast-induced Nephropathy, Acute Kidney Injury | Phase 2 | Completed | Barts & The London NHS Trust | 640 | 2018-11-29 | 2022-12-16 |
| Dentin Hypersensitivity Reduction Efficacy Clinical 0.454% stannous fluoride toothpaste, 5% potassium nitrate, 0.76% sodium monofluorophosphate - Dental Hypersensitivity | Phase 3 | Completed | Colgate Palmolive | 116 | 2018-11-26 | 2026-07-31 |
| The Effect of Orally Administrated Nitrate on Renal Parameters and Systemic Haemodynamics isotonic saline 9%, Potassium nitrate, Potassium chloride - Hypertension | Not applicable | Completed | Frank Mose | 18 | 2018-09-01 | 2021-02-21 |
| Targeting Pulsatile Load to Increase Exercise Capacity and Quality of Life After Aortic Valve Replacement for Severe Aortic Stenosis (PULSE AS) Potassium Nitrate, Potassium Chloride - Aortic Valve Stenosis | Phase 2 | Completed | University of Pennsylvania | 5 | 2018-05-01 | 2020-06-17 |
| Inorganic NItrate and EXercise Performance in Heart Failure (iNIX-HF): Dose Response KNO3, potassium nitrate - Heart Failure | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 42 | 2017-10-31 | 2025-05-20 |
| Clinical and Radiographic Assessments of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate as Pulpotomy Biomaterials in Immature Mandibular First Permanent Molars Potassium Nitrate in Polycarboxylate cement - Pulpotomy of Immature Lower First Molar(Apexegenesis) | Not applicable | Unknown | Cairo University | 50 | 2017-06-01 | 2017-05-25 |
Showing 20 of 34. Sign in to see all of them.
Dentin Sensitivity (13) · Heart Failure (4) · Hypertension (3) · Dental Pulp Diseases (2) · Tooth Erosion (2) · Acute Coronary Syndrome (1) · Acute Kidney Injury (1) · Aortic Valve Stenosis (1) · Cardiovascular Diseases (1) · Heart Failure, Diastolic (1) · Inflammation (1) · Obesity (1) · Overweight (1) · Toothache (1)
GlaxoSmithKline (6) · University of Pennsylvania (5) · Universidade Federal do Para (4) · Cairo University (2) · Washington University School of Medicine (2) · Ain Shams University (1) · Barts & The London NHS Trust (1) · Colgate Palmolive (1) · Colorado State University (1) · Frank Mose (1) · Karolinska Institutet (1) · Maastricht University Medical Center (1) · Minia University (1) · The University of Texas Health Science Center at San Antonio (1) · Universidade Federal Fluminense (1)
United States (14) · Brazil (4) · United Kingdom (4) · Egypt (3) · Canada (1) · Chile (1) · Denmark (1) · Netherlands (1) · Sweden (1) · Turkey (Türkiye) (1)
Payman Zamani, MD (3) · Linda R Peterson, MD (2) · Amrita Ahluwalia, PhD (1) · Andrew R Coggan, PhD (1) · Bennett T Amaechi, BDS, MS, PhD (1) · Farid Ayad (1) · Farid MS El-Askary, Professor (1) · Jesper N Bech, Ph.D., M.D. (1) · Jessica Virgili, MSc (1) · Jesuina L Nogueira Araujo, doutoura (1) · Jon Lundberg, MD, PhD (1)
PMID 26964798, PMID 27927683, PMID 29696420, PMID 30803493, PMID 31737860, PMID 32091599, PMID 33764198, PMID 35843050, PMID 38513060, PMID 39693096, PMID 39810073, PMID 40024965, PMID 41724486
2016 (1)