21 completed, 5 unknown, 2 recruiting, 1 active not recruiting. 30 Phase 3, 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 30 | Completed 21, Unknown 5, Recruiting 2, Active not recruiting 1, Not yet recruiting 1 |
| Phase 2 | 8 | Completed 4, Unknown 2, Active not recruiting 1, Not yet recruiting 1 |
Follow Dentin Sensitivity: new trials by email Literature Review of Dentin Sensitivity trials Research Report on Dentin Sensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Efficacy of Different Dentin Occluding Toothpaste Technologies 8% arginine + Zinc toothpaste, 5% Calcium Sodium Phosphosilicate toothpaste, 8% arginine toothpaste - Dentinal Sensitivity, Dentinal Hypersensitivity | Phase 3 | Recruiting | Colgate Palmolive | 132 | 2026-06-29 | 2026-08-07 |
| Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite Restorations Drug/Agent: Gluma Desensitizer, Drug/Agent: No desensitizer (Control) - Post-operative Sensitivity, Dentin Hypersensitivity | Phase 2 / Phase 3 | Not yet recruiting | Beenish Hassan | 60 | 2025-12-01 | 2025-09-23 |
| Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice Stannous fluoride and Potassium nitrate Dentifrice, Stannous fluoride Dentifrice, Potassium nitrate Dentifrice - Dentin Hypersensitivity | Phase 3 | Completed | HALEON | 688 | 2025-09-16 | 2026-08-25 |
| To Assess the Efficacy of a Toothpaste Containing 8% Arginine as Compared to Colgate Cavity Protection Toothpaste in the Reduction of Dentinal Hypersensitivity. TOMs of Maine Sensitive SLS Free Xtra Fresh, Colgate Cavity protection toothpaste - Sensitivity, Tooth | Phase 3 | Completed | Colgate Palmolive | 84 | 2025-08-18 | 2025-11-05 |
| Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Toothpaste test toothpaste, Control toothpaste - Dentin Hypersensitivity | Phase 3 | Completed | Colgate Palmolive | 80 | 2025-05-10 | 2026-03-19 |
| Effectiveness of Resin-Based Desensitizer and Laser, Compared to Fluoride Varnish in Management of Dentine Hypersensitivity in Non-carious Cervical Lesions Resin-Based Desensitizer, Laser Desensitizer, Fluoride-Based Desensitizer - Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG, Dentin Hypersensitivity | Phase 2 / Phase 3 | Active not recruiting | British University In Egypt | 84 | 2025-04-01 | 2025-08-13 |
| Dentinal Hypersensitivity Reduction Efficacy Study CSPR Toothpaste, Colgate Dental Cream Toothpaste - Sensitivity, Tooth | Phase 3 | Completed | Colgate Palmolive | 95 | 2025-03-04 | 2026-03-19 |
| Efficacy of a Potassium Nitrate Containing Herbal Mouthwash to a Potassium Oxalate Mouthwash in Dentinal Hypersensitivity Mouthwash preparation - Dentin Hypersensitivity | Phase 3 | Recruiting | Dr. D. Y. Patil Dental College & Hospital | 40 | 2025-02-25 | 2025-02-13 |
| Bioadhesive Film of Acmella Oleracea (Jambu) in the Reduction of Post-bleaching Dental Sensitivity Caused by Bleaching With 35% Hydrogen Peroxide. Bioadhesive film of Acmella Oleracea (jambu), Gel containing 5% potassium nitrate and 2% sodium fluoride., Spilanthol-free bioadhesive bioplastic film - Tooth Sensitivity, Teeth Whitening | Phase 3 | Completed | Universidade Federal do Para | 72 | 2024-04-01 | 2026-03-17 |
| Pregabalin Gel in Reducing Post-operative Tooth Sensitivity Surgery Caused by Bleaching With 35% Hydrogen Peroxide pregabalin gel, gel with 5% potassium nitrate and 2% sodium fluoride, Placebo gel - Tooth Bleaching, Sensitivity, Tooth | Phase 3 | Unknown | Universidade Federal do Para | 75 | 2024-01-05 | 2023-12-22 |
| Clinical Assessment of Bifluorid 10 vs Varnish Fluoride on The Exposed Hypersensitive Cervical Dentin in Adult Patient Bifluorid 10 ,VOCO, Sodium Fluoride 5% Dental Varnish - Hypersensitivity, Dentin Sensitivity | Phase 2 / Phase 3 | Unknown | Cairo University | 68 | 2020-10-01 | 2020-07-24 |
| Clinical Evaluation of Efficacy of Shield Force Plus Varnish VS Sodium Fluoride on Dentin Hypersensitivity TOKUYAMA SHIELD FORCE PLUS, Sodium Fluoride 5% Dental Varnish - Dentin Hypersensitivity, Dentin Desensitizing Agents | Phase 2 / Phase 3 | Unknown | Cairo University | 68 | 2020-10-01 | 2020-07-24 |
| Dentinal Hypersensitivity Reduction Colgate SNF, Sensodyne Extra Whitening, Colgate Fluoride (CDC) - Dentinal Hypersensitivity | Phase 3 | Completed | Colgate Palmolive | 123 | 2020-09-28 | 2026-03-18 |
| Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth 38% Silver Fluoride and Potassium Iodide solution (generic name; Riva Star®), Sodium fluoride varnish (generic name; Duraphat®) - Dentin Hypersensitivity, Active Dental Caries | Phase 2 / Phase 3 | Completed | University Medicine Greifswald | 30 | 2020-01-13 | 2021-05-06 |
| Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH Fluoro-Calcium-Phospho-Silicate based dentifrices, 8% Arginine based dentifrices, 8% Strontium Acetate - Dentin Hypersensitivity | Phase 3 | Completed | Dow University of Health Sciences | 140 | 2019-09-27 | 2021-05-11 |
| Comparison Of The Effect Of Propolis And Gluma Desensitizer On The Management Of Dentin Hypersensitivity Propolis, Gluma Desensitizer - Dentin Hypersensitivity | Phase 2 / Phase 3 | Completed | Dow University of Health Sciences | 40 | 2018-12-16 | 2021-03-29 |
| Efficacy of Seventh Generation Bonding Agents as Short-Term Desensitizers Among Patients With Hypersensitivity Single Bond Universal, Bifluorid 12, Xeno V+ - Dentin Hypersensitivity | Phase 3 | Completed | Dow University of Health Sciences | 105 | 2018-03-07 | 2020-01-18 |
| Comparison of Different Desensitizers in Reducing Dentinal Hypersensitivity 5% fluoride varnish, 8% arginine containing paste, Self-adhesive resin - Dentine Hypersensitivity | Phase 3 | Unknown | Aga Khan University | 60 | 2017-05-03 | 2018-06-29 |
| Fluoride Varnish X Glass Ionomer Sealant on Cervical Dentin Hypersensitivity Fluoride Varnish, Glass Ionomer Sealant, Placebo Group - Dentin Hypersensitivity, Dentin Sensitivity | Phase 3 | Completed | University of Sao Paulo | 121 | 2017-01-01 | 2020-10-20 |
| Piroxicam-beta-Cyclodextrin on Tooth Sensitivity Caused by In-office Bleaching Piroxicam-Beta-Cyclodextrin, Placebo - Tooth Sensitivity, Toothache | Phase 3 | Completed | Universidade Federal de Sergipe | 50 | 2016-12-13 | 2017-11-09 |
Showing 20 of 30. Sign in to see all of them.
Hypersensitivity (3) · Dental Caries (1) · Gingival Recession (1) · Toothache (1)
Stomatognathic Diseases (30) · Tooth Diseases (30) · Immune System Diseases (3) · Facial Pain (1) · Gingival Diseases (1) · Mouth Diseases (1) · Neurologic Manifestations (1) · Pain (1) · Pathological Conditions, Signs and Symptoms (1) · Periodontal Atrophy (1) · Periodontal Diseases (1) · Signs and Symptoms (1) · Tooth Demineralization (1)
Sodium Fluoride (6) · Tin Fluorides (6) · fluorophosphate (5) · potassium nitrate (3) · Arginine (2) · Gluma (2) · Bifluorid 12 (1) · CMW cement (1) · Carbamide Peroxide (1) · Centers for Disease Control and Prevention, U.S. (1) · Control Groups (1) · Fluorides (1) · Gels (1) · Hydrogen Peroxide (1) · Oxalic Acid (1)
Colgate Palmolive (6) · GlaxoSmithKline (5) · Dow University of Health Sciences (3) · Cairo University (2) · Universidade Federal de Sergipe (2) · Universidade Federal do Para (2) · Aga Khan University (1) · Beenish Hassan (1) · British University In Egypt (1) · Dr. D. Y. Patil Dental College & Hospital (1) · Federal University of Pelotas (1) · HALEON (1) · Universidade Federal de Santa Maria (1) · University Medicine Greifswald (1) · University of Chile (1)
United States (8) · Brazil (6) · Pakistan (5) · China (2) · Chile (1) · Egypt (1) · Germany (1) · India (1) · Ireland (1)
Aline C Peixoto (2) · Augusto Elias, DDS (1) · Cassiano K Rosing, PhD (1) · Fabricio B Zanatta, pHD (1) · Farid Ayad (1) · Farid Ayad, DMD, MSD (1) · Jeffery L Milleman (1) · Jesuina L Nogueira Araujo, doutoura (1) · John T Gallob (1) · Marina Shah, BDS (1) · Mohamed H Abudrya, BDS, MSc. (1) · Muhammad Hasan Hameed, BDS (1)
PMID 27093773, PMID 26437498, PMID 31164116, PMID 34615511, PMID 34676918, PMID 38745306, PMID 38783427, PMID 40024965