15 completed, 6 unknown, 2 not yet recruiting, 1 active not recruiting. 25 Phase 2, 8 Phase 3, 4 Phase 1.
Follow Dentin Sensitivity: new trials by email Literature Review of Dentin Sensitivity trials Research Report on Dentin Sensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite Restorations Drug/Agent: Gluma Desensitizer, Drug/Agent: No desensitizer (Control) - Post-operative Sensitivity, Dentin Hypersensitivity | Phase 2 / Phase 3 | Not yet recruiting | Beenish Hassan | 60 | 2025-12-01 | 2025-09-23 |
| Effectiveness of Resin-Based Desensitizer and Laser, Compared to Fluoride Varnish in Management of Dentine Hypersensitivity in Non-carious Cervical Lesions Resin-Based Desensitizer, Laser Desensitizer, Fluoride-Based Desensitizer - Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG, Dentin Hypersensitivity | Phase 2 / Phase 3 | Active not recruiting | British University In Egypt | 84 | 2025-04-01 | 2025-08-13 |
| Efficacy of Tooth Bleaching With 35% and 6% Hydrogen Peroxide in Primary Dentition Tooth Bleaching with Whiteness HP Automixx 35%, Tooth Bleaching with Whiteness HP Automixx 6% - Sensitivity, Tooth | Phase 1 / Phase 2 | Not yet recruiting | University of Nove de Julho | 38 | 2025-03-01 | 2024-11-04 |
| Phase 2 Study of KH001 in Long-term Relief From Dentin Hypersensitivity KH001, Placebo - Dentin Hypersensitivity | Phase 2 | Completed | HysensBio Co., Ltd | 120 | 2024-10-08 | 2026-10-29 |
| Effect of Pregabalin Gel in Controlling Cervical Dentin Hypersensitivity Placebo Treatment, Nitrate Potassium Treatment, Pregabalin Treatment - Dentin Sensitivity | Phase 2 | Unknown | Jesuína Lamartine Nogueira Araújo | 18 | 2024-05-28 | 2024-05-17 |
| A Study to Evaluate the Efficacy and Safety of KH001 in Patients with Dentin Hypersensitivity KH001, Placebo - Dentin Hypersensitivity | Phase 2 | Completed | HysensBio Co., Ltd | 171 | 2024-03-19 | 2025-03-14 |
| Managing Dentine Hypersensitivity With Silver Diamine Fluoride on Older Adults SDF, KNO3 - Dentine Hypersensitivity | Phase 2 | Unknown | The University of Hong Kong | 166 | 2023-02-01 | 2023-07-25 |
| Evaluation of the Safety and Tolerability of KH001 in Dentin Hypersensitivity Patients KH001, Placebo - Dentin Sensitivity | Phase 1 / Phase 2 | Completed | HysensBio Co., Ltd | 40 | 2021-06-14 | 2025-02-26 |
| The Desensitizing Treatment Effects of the Laser and Ozone on Dentin Hypersensitivity: In-vivo Comparison Gas ozone, Diode laser and desensitized gel - Dentin Sensitivity | Phase 2 | Completed | University of L'Aquila | 44 | 2021-02-27 | 2023-05-10 |
| Control of Pain Due to Dentin Hypersensitivity in Individuals With Molar-incisor Hypomineralization Hygiene Instructions, Sealant application, Low-level Laser - Dentin Sensitivity, Molar Incisor Hypomineralization | Phase 1 / Phase 2 | Unknown | University of Nove de Julho | 140 | 2021-01-01 | 2020-11-30 |
| Clinical Assessment of Bifluorid 10 vs Varnish Fluoride on The Exposed Hypersensitive Cervical Dentin in Adult Patient Bifluorid 10 ,VOCO, Sodium Fluoride 5% Dental Varnish - Hypersensitivity, Dentin Sensitivity | Phase 2 / Phase 3 | Unknown | Cairo University | 68 | 2020-10-01 | 2020-07-24 |
| Clinical Evaluation of Efficacy of Shield Force Plus Varnish VS Sodium Fluoride on Dentin Hypersensitivity TOKUYAMA SHIELD FORCE PLUS, Sodium Fluoride 5% Dental Varnish - Dentin Hypersensitivity, Dentin Desensitizing Agents | Phase 2 / Phase 3 | Unknown | Cairo University | 68 | 2020-10-01 | 2020-07-24 |
| Pain Control in Dentin Hypersensitivity in Patients With MIH Hygiene Guidance, Sealant Application, Low Level Laser Application - Hypersensitivity Dentin | Phase 1 / Phase 2 | Unknown | University of Nove de Julho | 140 | 2020-03-20 | 2020-02-13 |
| Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth 38% Silver Fluoride and Potassium Iodide solution (generic name; Riva Star®), Sodium fluoride varnish (generic name; Duraphat®) - Dentin Hypersensitivity, Active Dental Caries | Phase 2 / Phase 3 | Completed | University Medicine Greifswald | 30 | 2020-01-13 | 2021-05-06 |
| Study to Characterize the Efficacy of a Dual Active Dentifrice for the Relief of Dentin Hypersensitivity Potassium Nitrate, Stannous Fluoride - Dentin Hypersensitivity, Dentin Sensitivity | Phase 2 | Completed | GlaxoSmithKline | 123 | 2019-05-13 | 2020-09-11 |
| Comparison Of The Effect Of Propolis And Gluma Desensitizer On The Management Of Dentin Hypersensitivity Propolis, Gluma Desensitizer - Dentin Hypersensitivity | Phase 2 / Phase 3 | Completed | Dow University of Health Sciences | 40 | 2018-12-16 | 2021-03-29 |
| A Clinical Method Development Study to Characterise The Efficacy of a Dentifrice For The Relief Of Dentin Hypersensitivity Dentifrice containing 5% w/w KNO3 and 0.454% w/w SnF2 (1100 ppm fluoride)., Dentifrice containing 0.454% w/w SnF2 (1100 ppm fluoride). - Dentin Sensitivity | Phase 2 | Withdrawn | GlaxoSmithKline | 2018-10-01 | 2019-02-15 | |
| A Study to Assess Efficacy of an Experimental Oral Rinse in Providing Long Term Relief From Dentinal Hypersensitivity Potassium oxalate, Sodium fluoride, Placebo - Dentin Sensitivity | Phase 2 | Completed | GlaxoSmithKline | 89 | 2017-08-07 | 2018-11-14 |
| Different Concentrations of Potassium Nitrate in In-office Tooth Bleaching Sensitivity 3% potassium nitrate and 0.25% sodium fluoride, 5% potassium nitrate and 2% sodium fluoride - Tooth Sensitivity | Phase 2 | Completed | Universidade Federal do Amazonas | 56 | 2016-12-21 | 2017-10-27 |
| Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and Cream Control toothpaste containing Novamin® technology, Control toothpaste containing 1500 ppm fluoride as MFP, Test toothpaste with nano-HAP (high concentration) - Dentin Sensitivity | Phase 2 | Completed | The University of Texas Health Science Center at San Antonio | 203 | 2015-05-01 | 2018-11-16 |
Showing 20 of 25. Sign in to see all of them.
Hypersensitivity (2) · Dental Caries (1) · Molar Hypomineralization (1)
Stomatognathic Diseases (25) · Tooth Diseases (25) · Immune System Diseases (2) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Dental Enamel Hypomineralization (1) · Developmental Defects of Enamel (1) · Stomatognathic System Abnormalities (1) · Tooth Abnormalities (1) · Tooth Demineralization (1)
Sodium Fluoride (6) · potassium nitrate (5) · Gluma (2) · Control Groups (1) · Lasers, Semiconductor (1) · Low-Level Light Therapy (1) · Oxalic Acid (1) · Propolis (1) · Tin Fluorides (1) · Tokuyama Shield Force Plus (1) · Tooth Bleaching (1) · Vidrion-R (1) · gluma desensitizer (1) · silver fluoride (1) · sodium fluoride topical preparation (1)
GlaxoSmithKline (6) · HysensBio Co., Ltd (3) · University of Nove de Julho (3) · Cairo University (2) · Beenish Hassan (1) · British University In Egypt (1) · Dow University of Health Sciences (1) · Federal University of Pelotas (1) · Jesuína Lamartine Nogueira Araújo (1) · The University of Hong Kong (1) · The University of Texas Health Science Center at San Antonio (1) · Universidade Federal de Santa Maria (1) · Universidade Federal do Amazonas (1) · University Medicine Greifswald (1) · University of L'Aquila (1)
United States (6) · Pakistan (2) · South Korea (2) · Brazil (1) · Canada (1) · China (1) · Egypt (1) · Germany (1) · Italy (1)
Bennett T Amaechi, BDS, MS, PhD (1) · Fabricio B Zanatta, pHD (1) · Hatice Hasturk (1) · Jesuina L Nogueira Araujo, Doctor (1) · Kyoung-Kyu Choi, D.D.S (1) · Leandro M Martins, doctorate (1) · Marina Shah, BDS (1) · Maurizio D'Amario (1) · Mohamed H Abudrya, BDS, MSc. (1) · Rafael G Lund, PhD (1)
PMID 30803493, PMID 33692185, PMID 36286004, PMID 37454789, PMID 38783427