47 completed, 9 unknown, 1 not yet recruiting, 1 withdrawn. 27 Phase 3, 18 Not applicable, 4 Early Phase 1, 4 Phase 1, 4 Phase 4.
Follow Fluorides: new trials by email Literature Review of Fluorides trials Research Report on Fluorides
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Performance and Remineralization Potential of Self- Assembling Peptide P11-4 Containing Fluoride Versus Er, Cr: YSGG Laser Treatment and Micro Tensile Bond Strength of Giomer Restoration in Carious Lesions Curodont Repair Fluoride Plus (Self-assembling peptide remineralization agent)P11-4 peptide, fluoride, mild acidic buffer (pH ~4.5) , Credentis AG, Switzerland, Beautifil II LS - Remineralization Potential, Dentin Caries | Early Phase 1 | Not yet recruiting | Al-Azhar University | 21 | 2025-09-15 | 2025-07-29 |
| Effect of Different Remineralizing Agents on White Spot Lesions Treatment in Children Casein phosphopeptide-amorphous calcium phosphate, Casein phosphopeptide-amorphous calcium phosphate + fluoride, Nano hydroxyapatite paste - White Spot Lesion of Tooth | Not applicable | Completed | National Research Centre, Egypt | 100 | 2024-12-01 | 2025-02-12 |
| Maintaining Oral Health With Bio-products Mouth rinse 1, Mouth rinse 2, Mouth rinse 3 - Dental Caries, Dental Erosion | Not applicable | Completed | University of Bern | 12 | 2024-11-01 | 2025-09-23 |
| Effect of an Experimental Gel Based on Acmella Oleracea Extract Associated or Not With Fluoride on Dentin Hypersensitivity CT- control group, NP- Potassium nitrate gel, AO - Acmella Oleracea Extract Gel - Dentin Desensitizers, Non-carious Cervical Lesions | Not applicable | Completed | Universidade Federal do Para | 100 | 2024-08-20 | 2025-05-21 |
| The Remineralization of Early Enamel Caries in Permanent Teeth self assembling peptide p11-4 with fluoride, 5% sodium fluoride varnish - White Spot Lesion | Phase 1 | Unknown | Tanta University | 50 | 2024-06-06 | 2024-05-23 |
| Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study Fluoride - Molar Incisor Hypomineralization | Not applicable | Unknown | Universidad Nacional Autonoma de Mexico | 100 | 2024-03-01 | 2024-04-12 |
| Dentine Hypersensitivity Treated With Laser and Fluoride. Laser and Fluoride, Fluoride - Sensitive Dentin | Not applicable | Unknown | University of Pavia | 43 | 2024-01-15 | 2024-02-20 |
| Effectiveness of Different Remineralizing Strategies on the Management of Early Carious Lesions in Primary Teeth self assmbling peptide p11-4 combined with 0.05% fluoride, Casein phosphopeptide amorphous calcium phosphate, 5% sodium fluoride varnish - White Spot Lesion | Early Phase 1 | Completed | Alexandria University | 66 | 2023-08-15 | 2025-01-29 |
| Assessment of the Cytotoxic and Genotoxic Effect of Toothpastes With Different Forms of Fluoride on the Buccal Mucosa Toothpaste without fluoride, Toothpaste with sodium fluoride, Toothpaste with sodium monofluorophosphate - DNA Damage | Not applicable | Unknown | University of Zagreb | 80 | 2022-11-01 | 2022-10-27 |
| Toothpastes With Thermal Water for Oral Health BUCCOTHERM® Sensitive Gums with Fluoride, BUCCOTHERM® Sensitive Gums Fluoride-Free - Gingivitis, Dentin Hypersensitivity | Phase 4 | Completed | I.M. Sechenov First Moscow State Medical University | 84 | 2022-11-01 | 2023-03-01 |
| Effect of Different Desensitizing Agents on Post-bleaching Hypersensitivity and Shade Stability Potassium nitrate with fluoride, Casein phosphopeptide-amorphous calcium phosphate with fluoride, Hydroxyapatite with fluoride - Tooth Hypersensitivity | Phase 4 | Completed | Ain Shams University | 48 | 2021-11-13 | 2024-04-23 |
| Evaluation of Caries Prevention Based on Genetic Etiology and Risk. Fluoride - Caries,Dental | Not applicable | Unknown | Umeå University | 520 | 2021-08-25 | 2022-10-31 |
| Remineralization Potential of Curodont Repair Flouride Plus Versus CPP-ACP in Management of White Spot Lesions: Randomized Clinical Trial Self assembling peptide with fluoride - White Spot Lesion | Not applicable | Unknown | Cairo University | 48 | 2020-02-01 | 2020-01-29 |
| The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract Miswak, Grape Seed Extract Mouthwash, fluoride - Dental Caries | Not applicable | Completed | Al-Azhar University | 30 | 2019-06-01 | 2019-10-23 |
| Remineralization Potential of MI Varnish Versus Fluoride Varnish on White Spot Lesions in Maxillary Primary Incisors MI varnish - Remineralization Effect of the Varnish on White Spot Lesions | Not applicable | Completed | Cairo University | 60 | 2019-03-01 | 2020-07-21 |
| Miswak Versus Standard Measures to Prevent the Incidence of Caries Young Egyptian Adults: A Randomized Controlled Clinical Trial miswak stick, Miswak plus tooth brushing and tooth paste, Standard preventive measures (tooth brushing , interdental cleaning and mouth rinse use containing CHX and Fluoride) - Dental Caries | Not applicable | Unknown | Cairo University | 82 | 2019-01-01 | 2020-02-25 |
| Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser Laser, Fluoride - Dental Caries | Not applicable | Completed | University of California, San Francisco | 60 | 2018-02-08 | 2021-01-28 |
| EVALUATION OF AN ALTERNATIVE TECHNIQUE FOR THE APPLICATION OF SODIUM FLUOROPHOSPHATE: A 2-YEARS DOUBLE-BLIND RCT Fluoride - Caries,Dental | Phase 4 | Completed | University of Buenos Aires | 300 | 2017-04-01 | 2023-04-12 |
| Effect of Different Pastes on Remineralization of Early Caries Lesions in Primary Teeth CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP) - White Spot Lesion of Tooth | Not applicable | Completed | Jordan University of Science and Technology | 118 | 2016-03-01 | 2018-05-16 |
| Antimicrobial Effect of Different Pastes on Streptococcus Mutans in Children CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP) - Mutans Streptococci, Oral Health | Not applicable | Completed | Jordan University of Science and Technology | 127 | 2016-03-01 | 2018-05-16 |
Showing 20 of 58. Sign in to see all of them.
Dental Caries (12) · Dental Plaque (9) · Gingival Diseases (6) · Dentin Sensitivity (5) · Gingivitis (3) · Periodontal Diseases (3) · Periodontitis (2) · Plaque, Amyloid (2) · Bacteremia (1) · Dry Socket (1) · Fetal Membranes, Premature Rupture (1) · Molar Hypomineralization (1) · Mucositis (1) · Obstetric Labor, Premature (1) · Peri-Implantitis (1)
Colgate Palmolive (23) · GlaxoSmithKline (6) · Cairo University (3) · Al-Azhar University (2) · Jordan University of Science and Technology (2) · Ain Shams University (1) · Alexandria University (1) · Arwa Owais (1) · Ege University (1) · Federal University of Paraíba (1) · Hadassah Medical Organization (1) · I.M. Sechenov First Moscow State Medical University (1) · Indiana Nanotech, LLC (1) · Johns Hopkins University (1) · National Research Centre, Egypt (1)
United States (24) · Egypt (8) · Brazil (3) · Australia (2) · Israel (2) · Italy (2) · Jordan (2) · Switzerland (2) · Argentina (1) · Croatia (1) · Germany (1) · India (1) · Mexico (1) · Russia (1) · Spain (1)
Gregory Seymour, BDS (2) · Ola Al-Batayneh, MDSc, FRACDS (2) · Patricia Corby, DDS (2) · Yanfang Ren, DDS (2) · Andrea Scribante, DDS PhD MSc (1) · Arwa I Owais, BDS, MS (1) · Augusto E Boneta, DDS (1) · Augusto Elias, DDS (1) · Bernal Stewart (1) · Cecy M Silva (1) · Daniel Fine, DDS (1) · Denis Kinane, BDS (1)
PMID 10477976, PMID 19711612, PMID 20831669, PMID 21269037, PMID 24283282, PMID 24310847, PMID 26346538, PMID 26492796, PMID 29191562, PMID 30328176, PMID 32803438, PMID 39096337, PMID 40830200, PMID 42693341, PMID 9442423