19 recruiting, 17 unknown, 15 completed, 3 not yet recruiting. 58 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 58 | Recruiting 19, Unknown 17, Completed 15, Not yet recruiting 3, Active not recruiting 2, Terminated 2 |
Follow Deep Brain Stimulation: new trials by email Literature Review of Deep Brain Stimulation trials Research Report on Deep Brain Stimulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia DBS - Dystonia, Pediatric | Not applicable | Recruiting | Children's Hospital Medical Center, Cincinnati | 75 | 2026-09-01 | 2026-10-20 |
| Investigating the Increased Risk of Falls in Individuals With Parkinson's Disease Treated With Deep Brain Stimulation DBS as part of standard of care - Deep Brain Stimulation, PARKINSON DISEASE (Disorder) | Not applicable | Recruiting | University of Alabama at Birmingham | 20 | 2026-08-01 | 2026-10-26 |
| Safety and Tolerability of Patterned Stimulation for DBS in the Home Setting Biphasic deep brain stimulation, Conventional deep brain stimulation, Theta burst deep brain stimulation - Parkinson Disease, Deep Brain Stimulation | Not applicable | Recruiting | University of Florida | 60 | 2026-05-06 | 2026-07-06 |
| Comparing Biomarker-Guided DBS Programming With Standard Clinical Monopolar Programming Conventional DBS Programming (Monopolar Review), Objective-Guided DBS Programming (Imaging and Local Field Potential-Based) - Parkinson's Disease, Parkinson | Not applicable | Not yet recruiting | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 20 | 2026-03-01 | 2026-01-27 |
| Adaptive vs. Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease Adaptive DBS, Continue DBS - Deep Brain Stimulation, Parkinson Disease | Not applicable | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 130 | 2026-01-27 | 2026-01-29 |
| LIFUS For Neurological Disorders LIFUS, Sham LIFUS - Parkinson's Disease (PD), Essential Tremor | Not applicable | Recruiting | University Health Network, Toronto | 50 | 2025-12-02 | 2026-08-13 |
| Testing of an Interface for Synchronizing tACS-DBS With a Phase-locked-loop DBS-coupled tACS - Deep Brain Stimulation, Parkinson's Disease (PD) | Not applicable | Completed | Universitätsklinikum Hamburg-Eppendorf | 2 | 2025-09-30 | 2026-06-30 |
| Effect of Mediterranean Diet on Nutrition in Parkinson's Disease Patients With Bilateral Subthalamic Deep Brain Stimulation Mediterranean diet - Parkinson Disease, Deep Brain Stimulation | Not applicable | Recruiting | Ankara University | 24 | 2025-09-25 | 2025-12-03 |
| Revision of Deep Brain Stimulator in Patients With Parkinson's Disease Patients who underwent surgery under general anesthesia, Patients who underwent surgery under regional anesthesia - Pain Management, Regional Anesthesia | Not applicable | Recruiting | Ankara Etlik City Hospital | 50 | 2025-09-20 | 2025-12-10 |
| VC/VS for Apathy in PD Deep Brain Stimulation - Parkinson Disease, Deep Brain Stimulation | Not applicable | Not yet recruiting | Nora Vanegas | 5 | 2025-09-01 | 2025-05-31 |
| Evaluating Modulation Effects of Temporal Interference Using SEEG Temporal Interference - Deep Brain Stimulation, Drug Resistant Epilepsy | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 20 | 2024-11-04 | 2025-02-05 |
| Impact of Frequency-specific Subthalamic Nucleus Subregion Stimulation on Inhibitory Control in Parkinson's Disease 5Hz stimulation on the STN motor subregion, 5Hz stimulation on the STN associative subregion, 130Hz stimulation on the STN motor subregion - Parkinson Disease, Deep Brain Stimulation | Not applicable | Recruiting | Beijing Tiantan Hospital | 20 | 2024-10-01 | 2025-06-15 |
| Multitarget Stereotactic Electrophysiological Recording and Stimulation for Tourette Syndrome New Target DBS, CM-DBS, Sham Stimulation - Tourette Syndrome, Deep Brain Stimulation | Not applicable | Recruiting | Beijing Tiantan Hospital | 5 | 2024-10-01 | 2025-05-22 |
| Effect of Physical Activity on the Course of Parkinson's Disease in Patients With Bilateral DBS-STN Stimulation. Physiotherapy, Education about physiotherapy - Parkinson Disease, Deep Brain Stimulation | Not applicable | Recruiting | Medical University of Warsaw | 102 | 2024-09-05 | 2026-10-06 |
| Esketamine in Microelectrode Recording-guided Subthalamic Deep-Brain Stimulation for Parkinson's Disease esketamine, normal Saline - PD - Parkinson's Disease, Deep Brain Stimulation | Not applicable | Unknown | Beijing Tiantan Hospital | 102 | 2024-08-09 | 2024-08-09 |
| Dual-task Augmented Reality for PD DBS Multi-modal treatment - Parkinson's Disease, Deep Brain Stimulation | Not applicable | Completed | Jay Alberts | 7 | 2024-05-21 | 2025-09-30 |
| The BRAINMAP-DBS Study: BRain Network AnalysIs usiNg 7-Tesla MRI and MAgnetoencephalograPhy for Deep Brain Stimulation magnetoencephalography - Deep Brain Stimulation, Parkinson Disease | Not applicable | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 500 | 2024-04-23 | 2025-04-17 |
| Multicentre RCT of Awake Versus Asleep Tractography Based DBS for ET Awake DBS, Asleep DBS - Essential Tremor, Deep Brain Stimulation | Not applicable | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 110 | 2024-02-01 | 2025-04-13 |
| DBS Imaging-based vs. Threshold Assessment-based Programming Imaging-based programming, Threshold assessment-based programming - Deep Brain Stimulation, Parkinson Disease | Not applicable | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 132 | 2024-01-03 | 2026-11-12 |
| Dexmedetomidine Prevents Postoperative Delirium After Deep Brain Stimulation in Patients With Parkinson's Disease Dexmedetomidine, 0.9% saline - Dexmedetomidine, Postoperative Delirium | Not applicable | Unknown | Beijing Tiantan Hospital | 192 | 2023-12-01 | 2023-06-15 |
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Parkinson Disease (29) · Essential Tremor (6) · Dystonia (4) · Alzheimer Disease (3) · Movement Disorders (3) · Alcoholism (2) · Cognitive Dysfunction (2) · Gait Disorders, Neurologic (2) · Lethargy (2) · Obsessive-Compulsive Disorder (2) · Schizophrenia (2) · Substance-Related Disorders (2) · Tourette Syndrome (2) · Agnosia (1) · Alcohol Drinking (1)
Nervous System Diseases (47) · Central Nervous System Diseases (43) · Brain Diseases (37) · Neurodegenerative Diseases (36) · Movement Disorders (34) · Basal Ganglia Diseases (32) · Synucleinopathies (29) · Parkinsonian Disorders (28) · Pathological Conditions, Signs and Symptoms (17) · Signs and Symptoms (17) · Neurologic Manifestations (16) · Mental Disorders (15) · Dyskinesias (7) · Dementia (5) · Neurocognitive Disorders (5)
Deep Brain Stimulation (9) · Saline Solution (2) · Amyloid beta-Protein Precursor (1) · Anesthesia, General (1) · Conscious Sedation (1) · Dexmedetomidine (1) · Diagnostic Imaging (1) · Diet, Mediterranean (1) · Esketamine (1) · Ketamine (1) · Magnetoencephalography (1) · Memantine (1) · Microscopy, Fluorescence, Multiphoton (1) · Neuropsychological Tests (1) · Physical Therapy Modalities (1)
Beijing Tiantan Hospital (6) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (4) · Ruijin Hospital (4) · University of British Columbia (3) · Chinese PLA General Hospital (2) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (2) · Jay Alberts (2) · Shanghai Mental Health Center (2) · University Health Network, Toronto (2) · University of California, Los Angeles (2) · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) (1) · Ankara Etlik City Hospital (1) · Ankara University (1) · Beijing Municipal Administration of Hospitals (1) · Buddhist Tzu Chi General Hospital (1)
China (18) · United States (17) · Canada (5) · Netherlands (4) · Germany (3) · Israel (2) · Spain (2) · Turkey (Türkiye) (2) · Belgium (1) · France (1) · Poland (1) · Switzerland (1) · Taiwan (1) · United Kingdom (1)
Bomin Sun, PhD (2) · Jianguo Zhang, M.D., Ph.D. (2) · Min Zhao (2) · Andres M Lozano, MD, PhD (1) · Bettina C. Schwab, PhD (1) · Carmela Tartaglia, MD (1) · Christopher R Honey, MD, DPhil (1) · Cletus Cheyuo, MD, PhD (1) · Darlene Lobel, MD (1) · Idit O Tamir, MD (1) · Iluminada Corripio, PhD (1) · Jay Alberts, PhD (1) · Jianguo Zhang, MD, PhD (1) · Jianguo Zhang, Ph.D (1) · Jocelyne Bloch, MD (1)
PMID 11391740, PMID 19633906, PMID 19940187, PMID 21384292, PMID 28304188, PMID 29274834, PMID 33862624, PMID 34924027, PMID 37253497, PMID 37433729, PMID 38251897, PMID 39384245, PMID 41189627, PMID 41253805, PMID 41923626, PMID 42102350, PMID 42363278, PMID 42472285
K23NS149280 (1), R01AG073480 (1), R01NS109487 (1)