17 terminated. 17 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 17 | Terminated 17 |
Follow Craniocerebral Trauma: new trials by email Literature Review of Craniocerebral Trauma trials Research Report on Craniocerebral Trauma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Antiseizure Medication in Seizure Networks at Early Acute Brain Injury Phenobarbital Sodium Injection, Levetiracetam, Lacosamide Injectable Product - Brain Injuries, Acute, Brain Injuries, Traumatic | Phase 4 | Terminated | University of North Carolina, Chapel Hill | 5 | 2023-11-20 | 2025-11-14 |
| Pediatric Concussion Outcomes Nortriptyline, Placebo - Concussion Post Syndrome, Headaches Posttraumatic | Phase 4 | Terminated | Lancaster General Hospital | 8 | 2020-02-15 | 2025-09-10 |
| The CAPTAIN Trial: Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery Cerebrolysin, 0.9% NaCl, saline - Traumatic Brain Injury | Phase 4 | Terminated | Ever Neuro Pharma GmbH | 46 | 2013-09-01 | 2020-02-25 |
| Effect of Intrathoracic Pressure Regulation on Traumatic Brain Injury -7 cm H2O ITPR, -12cm H2O ITPR - Head Injury | Phase 4 | Terminated | Advanced Circulatory Systems | 1 | 2012-08-01 | 2015-02-16 |
| Functional Vision in TBI Vision Restoration Therapy, NVT Eye Scanning Therapy, Eccentric Viewing Training - Brain Injuries, Visually Impaired Persons | Phase 4 | Terminated | VA Office of Research and Development | 110 | 2012-06-01 | 2017-06-16 |
| A Comparison of Propofol Versus Midazolam to Sedate Critically Brain Injury; Measurement of Cytokine Response and Assessment of Function Intravenous sedation using propofol, Intravenous sedation with midazolam - Traumatic Brain Injury | Phase 4 | Terminated | Michigan State University | 1 | 2011-11-01 | 2025-09-10 |
| Enteral Nutrition and Glycemic Variability Neurological Intensive Care Unit Study Glycerna, Jevity - Control Diet - Subarachnoid Hemorrhage, Intracranial Hemorrhage | Phase 4 | Terminated | Eastern Virginia Medical School | 14 | 2011-11-01 | 2012-10-05 |
| Treximet for Prevention of Post Traumatic Headache Associated With Cognitive Dysfunction sumatriptan/naproxen sodium, Placebo - Post-Traumatic Headache | Phase 4 | Terminated | Cady, Roger, M.D. | 23 | 2010-05-01 | 2020-07-29 |
| Comparison of 2 Doses of Mannitol on Post Traumatic Intracranial Hypertension and Cerebral Monitoring variation of mannitol dose - Traumatic Brain Injury, Intracranial Hypertension | Phase 4 | Terminated | University Hospital, Grenoble | 3 | 2008-10-01 | 2012-11-08 |
| Treatment Of Adult Growth Hormone Deficiency After Traumatic Brain Injury Genotropin, Placebo - Brain Injuries, Growth Hormone Deficiency | Phase 4 | Terminated | Pfizer | 10 | 2008-03-01 | 2010-06-02 |
| Effect of Namenda on Short Term Memory and Attention in Patients With Mild to Moderate Traumatic Brain Injury Memantine, Placebo - Traumatic Brain Injury | Phase 4 | Terminated | University of Missouri-Columbia | 11 | 2007-04-01 | 2017-01-23 |
| Normoglycemia and Neurological Outcome Insulin, Conventional insulin treatment - Acute, Non-traumatic Subarachnoid Hemorrhage, Intraparenchymal Hemorrhage | Phase 4 | Terminated | University of Louisville | 56 | 2007-01-01 | 2022-01-04 |
| Role of Dexamethasone in the Conservative Treatment of Chronic Subdural Hematoma Dexamethasone, Placebo - Hematoma, Subdural, Chronic | Phase 4 | Terminated | CHU de Quebec-Universite Laval | 20 | 2007-01-01 | 2016-02-29 |
| Combining Observational and Physiologic Sedation Assessment Tools Ramsay Scale, Bispectral index monitor - Brain Injury | Phase 4 | Terminated | Duke University | 67 | 2006-11-01 | 2015-10-14 |
| Naratriptan for the Treatment of Post Traumatic Headache Associated With Cognitive Dysfunction naratriptan HCl - Post Traumatic Headache | Phase 4 | Terminated | Cady, Roger, M.D. | 12 | 2006-10-01 | 2013-02-11 |
| Duration of Postoperative Antibiotic Prophylaxis in Facial Fractures Amoxicillin/clavulanic acid, Amoxicillin plus placebo - Surgical Wound Infection | Phase 4 | Terminated | Insel Gruppe AG, University Hospital Bern | 217 | 2006-01-01 | 2013-07-15 |
| A Study to Evaluate the Efficacy of Somatropin in Adults With Growth Hormone Deficiency Caused by Trauma and/or Head Injury somatropin - Brain Injuries, Growth Hormone Deficiency Dwarfism | Phase 4 | Terminated | Pfizer | 100 | 2002-11-01 | 2008-04-01 |
Brain Injuries, Traumatic (8) · Brain Injuries (7) · Intracranial Hemorrhages (4) · Headache (3) · Post-Traumatic Headache (3) · Dwarfism, Pituitary (2) · Subarachnoid Hemorrhage (2) · Brain Concussion (1) · Brain Ischemia (1) · Cognitive Dysfunction (1) · Coma (1) · Facial Injuries (1) · Heart Arrest (1) · Hematoma, Subdural (1)
Nervous System Diseases (17) · Trauma, Nervous System (17) · Wounds and Injuries (17) · Brain Diseases (16) · Central Nervous System Diseases (16) · Pathological Conditions, Signs and Symptoms (9) · Brain Injuries (6) · Pathologic Processes (6) · Cardiovascular Diseases (5) · Cerebrovascular Disorders (5) · Hemorrhage (5) · Vascular Diseases (5) · Neurologic Manifestations (4) · Signs and Symptoms (4)
Human Growth Hormone (2) · Adrenal Cortex Hormones (1) · Amoxicillin (1) · Amoxicillin-Potassium Clavulanate Combination (1) · Calcium Dobesilate (1) · Consciousness Monitors (1) · Dexamethasone (1) · Insulin (1) · Levetiracetam (1) · Memantine (1) · Midazolam (1) · Naproxen (1) · Nortriptyline (1) · Phenobarbital (1) · Sodium Chloride (1)
Cady, Roger, M.D. (2) · Pfizer (2) · Advanced Circulatory Systems (1) · CHU de Quebec-Universite Laval (1) · Duke University (1) · Eastern Virginia Medical School (1) · Ever Neuro Pharma GmbH (1) · Insel Gruppe AG, University Hospital Bern (1) · Lancaster General Hospital (1) · Michigan State University (1) · University Hospital, Grenoble (1) · University of Louisville (1) · University of Missouri-Columbia (1) · University of North Carolina, Chapel Hill (1) · VA Office of Research and Development (1)
United States (11) · France (2) · Hong Kong (1) · Italy (1) · Netherlands (1) · Spain (1) · Sweden (1) · Switzerland (1) · United Kingdom (1)
Roger K Cady, MD (2) · Carmelo Graffagnino, MD FRCPC (1) · Chet A Morrison, M.D. (1) · DaiWai M Olson, PhD RN CCRN (1) · Emilio G. Cediel, MD (1) · George R. Johnstone, Ph.D. (1) · Gilles Francony, MD (1) · Laura DiPaolo, MD (1) · Olivier Lieger, MD, DMD (1) · Patrick Moreno, MD (1) · Rainer Lenhardt, MD (1) · Ron Schuchard, PhD (1) · S. Jon Rupright, D.O. (1)
2008 (1)