45 completed, 34 unknown, 33 recruiting, 15 not yet recruiting. 84 Not applicable, 15 Phase 2, 14 Phase 3, 8 Phase 4, 4 Phase 1.
Follow Hematoma, Subdural: new trials by email Literature Review of Hematoma, Subdural trials Research Report on Hematoma, Subdural
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Template-Guided Burr-Hole Drainage With Middle Meningeal Artery Coagulation for Chronic Subdural Hematoma Standard Burr-Hole Drainage Group, 3D-Printed Template-Guided Burr-Hole Drainage With Attempted MMA Coagulation Group - Chronic Subdural Hematoma | Not applicable | Not yet recruiting | The Second Hospital of Anhui Medical University | 440 | 2027-01-01 | 2026-07-23 |
| Intra-Arterial Bevacizumab as an Adjunct to Middle Meningeal Artery Embolization for Chronic Subdural Hematoma Bevacizumab (intra-arterial) - Chronic Subdural Hematoma | Phase 1 | Not yet recruiting | Dheeraj Gandhi | 18 | 2027-01-01 | 2026-07-27 |
| Frontal vs Parietal Eminence Drainage for Chronic Subdural Hematoma Frontal-region puncture drainage, Parietal Eminence region puncture drainage - Chronic Subdural Hematoma | Not applicable | Not yet recruiting | The Second Hospital of Anhui Medical University | 440 | 2027-01-01 | 2026-07-28 |
| PHIL™ Middle Meningeal Artery Embolization for First-Line Treatment of Chronic Subdural Hematoma IDE Trial PHIL™ (Precipitating Hydrophobic Injectable Liquid), Surgical evacuation - Chronic Subdural Hematomas | Not applicable | Not yet recruiting | Microvention-Terumo, Inc. | 475 | 2026-12-31 | 2026-05-08 |
| Propofol Target-Controlled Infusion Versus Dexmedetomidine for Sedation During Chronic Subdural Hematoma Surgery Under Local Anesthesia Dexmedetomidine, Propofol (Astra-Zeneca) - Chronic Subdural Hematoma | Phase 4 | Not yet recruiting | National Institute of Neurology, Tunisia | 60 | 2026-11-01 | 2026-11-03 |
| Outcomes of Traumatic Intracranial Hemorrhage in the Elderly Traumatic Brain Injury, Subdural Hematoma | Not yet recruiting | Assiut University | 50 | 2026-10-01 | 2026-09-16 | |
| Comparative Study of Embolic Agents in Patients With Subdural Hemorrhage Undergoing Middle Meningeal Artery (MMA) Embolization Particles (polyvinyl alcohol or similar microspheres), Liquid Embolics (Onyx, n-BCA, or equivalent), Phenox Coils (Avenir UNO Helical Coil) - Chronic Subdural Hematoma, Stroke | Not applicable | Not yet recruiting | Sanford Health | 30 | 2026-09-01 | 2026-08-11 |
| Middle Meningeal Artery Embolization in Patients With Chronic Subdural Hematoma middle meningeal artery embolization - Middle Meningeal Artery Embolization, Chronic Subdural Hematomas | Not applicable | Not yet recruiting | Assiut University | 35 | 2026-09-01 | 2026-09-08 |
| Post-Market Active Surveillance and Health Economic Evaluation of Cerebrovascular Diagnostic and Therapeutic Devices Endovascular Treatment for Acute Ischemic Stroke - Acute Ischemic Stroke, Intracranial Arterial Stenosis | Not yet recruiting | Changhai Hospital | 2000 | 2026-09-01 | 2026-09-18 | |
| MMA Embolization With NeoCast for Subacute and Chronic Subdural Hematoma NeoCast Embolic System, Onyx LES, an FDA-Approved Commercial Liquid Embolic - Subdural Hematoma | Not applicable | Recruiting | Arsenal Medical, Inc. | 360 | 2026-08-13 | 2026-09-30 |
| Middle Meningeal Artery Coagulation During Burr-Hole Drainage for Chronic Subdural Haematoma (BURR-MMA) CT-Guided Intra-Operative Middle Meningeal Artery Interruption - Chronic Subdural Hematomas | Not applicable | Recruiting | University College, London | 30 | 2026-08-01 | 2026-08-04 |
| Platelet Activity Monitoring for Patients Under Adp Medication Using Verify Now in Subdural Hematoma Biological samples - Hematoma, Subdural | Not applicable | Not yet recruiting | University Hospital, Brest | 40 | 2026-07-01 | 2026-06-08 |
| Prospective MMA Embolization Registry Middle Meningeal Artery Embolization - Chronic Subdural Hematomas | Not yet recruiting | Charite University, Berlin, Germany | 100 | 2026-07-01 | 2026-06-04 | |
| Chronic Subdural Hematoma Embolization With Detachable Coils Balt coils: (Balt USA, LLC), MMA embolization - Chronic Subdural Hemorrhage (cSDH) | Recruiting | Icahn School of Medicine at Mount Sinai | 150 | 2026-06-02 | 2026-09-25 | |
| Middle Meningeal Artery Embolisation in Chronic Subdural Hematoma Middle Meningeal Artery Embolisation - Chronic Subdural Hematoma | Not applicable | Recruiting | University Hospital Hradec Kralove | 200 | 2026-06-01 | 2026-11-05 |
| The Use of Tranexamic Acid in the Treatment of Symptomatic Subdural Hematoma Tranexamic acid (TXA), Placebo - Subdural Hematoma | Phase 3 | Recruiting | Unity Health Toronto | 130 | 2026-05-20 | 2026-05-29 |
| Study On Histoacryl Used For Embolization Of Middle Meningeal Artery (MMA) In Chronic Subdural Hematoma (CSDH) Histoacryl® - Subdural Hematoma, Subdural Hematoma, Chronic | Recruiting | Aesculap AG | 178 | 2026-04-10 | 2026-10-27 | |
| Non-Thermal Plasma to Reduce Recurrence in Chronic Subdural Hematoma Standard Surgery Protocol, Non-Thermal Plasma - Chronic Subdural Hematoma, Subdural Hematoma | Not applicable | Recruiting | Benjamín Gonzalo Rodríguez Méndez | 40 | 2026-03-02 | 2026-06-18 |
| Al Prediction of Sarcopenia Risk in Neurocritical ICU Patients Prospective Observational Assessment - Intracerebral Hemorrhage, Subarachnoid Hemorrhage | Completed | Trabzon Kanuni Education and Research Hospital | 72 | 2026-01-01 | 2026-09-24 | |
| Adjuvant Tranexamic Acid (TXA) Versus Surgery Alone for Adult Patients With Chronic Subdural Hematoma (CSDH) Tranexamic Acid (Cyklokapron) - Chronic Subdural Hematoma | Phase 2 / Phase 3 | Recruiting | St. Olavs Hospital | 274 | 2025-12-10 | 2026-07-17 |
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Hematoma, Subdural, Chronic (111) · Brain Injuries, Traumatic (18) · Craniocerebral Trauma (13) · Recurrence (12) · Hematoma, Epidural, Spinal (11) · Intracranial Hemorrhages (10) · Subarachnoid Hemorrhage (9) · Brain Contusion (8) · Brain Edema (8) · Brain Injuries (8) · Head Injuries, Closed (8) · Wounds and Injuries (8) · Brain Concussion (7) · Brain Hemorrhage, Traumatic (7)
Cardiovascular Diseases (151) · Pathologic Processes (151) · Pathological Conditions, Signs and Symptoms (151) · Vascular Diseases (151) · Cerebrovascular Disorders (150) · Intracranial Hemorrhage, Traumatic (148) · Nervous System Diseases (148) · Central Nervous System Diseases (147) · Hematoma (147) · Brain Diseases (146) · Hemorrhage (146) · Trauma, Nervous System (146) · Wounds and Injuries (143) · Intracranial Hemorrhages (141) · Craniocerebral Trauma (138)
Tranexamic Acid (9) · Dexamethasone (5) · Atorvastatin (4) · Propofol (4) · Surgical Procedures, Operative (4) · Trephining (4) · Craniotomy (3) · Adrenal Cortex Hormones (2) · Bevacizumab (2) · Calcium Dobesilate (2) · Dabigatran (2) · Ethanol (2) · Fentanyl (2) · Magnesium Sulfate (2) · Rivaroxaban (2)
Children's Hospital Medical Center, Cincinnati (7) · Beijing Tiantan Hospital (6) · Assiut University (3) · Chinese University of Hong Kong (3) · Huashan Hospital (3) · St. Olavs Hospital (3) · Unity Health Toronto (3) · University of New Mexico (3) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2) · Hamilton Health Sciences Corporation (2) · Icahn School of Medicine at Mount Sinai (2) · Kasr El Aini Hospital (2) · Ohio State University (2) · Oriental Neurosurgery Evidence-Based-Study Team (2) · Sahlgrenska University Hospital (2)
United States (39) · China (18) · Canada (12) · France (8) · Germany (7) · Egypt (5) · Sweden (5) · Switzerland (5) · Netherlands (4) · United Kingdom (4) · Finland (3) · Hong Kong (3) · India (3) · Italy (3) · Japan (3)
Weiming Liu, M.D. (4) · Shari L Wade, PhD (3) · Jared Knopman, MD (2) · Michael D Cusimano, MD, PhD (2) · Shari L. Wade, PhD (2) · Adam Arthur, MD, MPH (1) · Adam Burgoyne, MD, PhD (1) · Ajith J Thomas, MD (1) · Alejandro Tomasello, MD (1) · Alexander Coon (1) · Andreas Bartley, MD (1) · Andrew S Little, MD (1) · Ansaar Rai, MD (1) · Aria Nouri (1) · Asgeir Jakola, MD, PhD (1)
PMID 30413559, PMID 31405391, PMID 35170571, PMID 12359244, PMID 19782872, PMID 22746261, PMID 23640543, PMID 23753094, PMID 23790158, PMID 24781374, PMID 25583911, PMID 25738891, PMID 26461100, PMID 26581842, PMID 27059872, PMID 27150916, PMID 27847578, PMID 28287909, PMID 28389109, PMID 28583162, PMID 28644099, PMID 28836809, PMID 28935548, PMID 29019449, PMID 29021000, PMID 29096775, PMID 29097272, PMID 29617953, PMID 29762769, PMID 30073290, PMID 30418606, PMID 30499926, PMID 30665464, PMID 30738021, PMID 30798265, PMID 31004066, PMID 31556652, PMID 31664468, PMID 32565480, PMID 33344885, PMID 33787345, PMID 34022170, PMID 34487722, PMID 34518968, PMID 35042560, PMID 35133631, PMID 35351178, PMID 35593710, PMID 35996195, PMID 36129273
2023 (2), 2009 (1), 2015 (1), 2016 (1), 2017 (1), R01GM120484 (1), UG3NS128397 (1), UH3NS128397 (1)