85 completed, 33 unknown, 27 recruiting, 22 active not recruiting. 91 Not applicable, 27 Phase 2, 14 Phase 4, 12 Phase 3, 9 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical Therapy 177Lu-PSMA-I&T - escalating renal absorbed dose, 177Lu-PSMA-I&T - recommended phase 2 regime - Cancer, Prostate Cancer | Phase 1 / Phase 2 | Not yet recruiting | CHU de Quebec-Universite Laval | 500 | 2028-03-01 | 2025-03-30 |
| Acceptability of a Nurse-led Telehealth Remote Self-monitoring Model of Care in Patients With Rheumatoid Arthritis Nurse-led telehealth remote self-monitoring - Rheumatoid Arthritis (RA) | Not applicable | Not yet recruiting | CHU de Quebec-Universite Laval | 104 | 2027-01-01 | 2026-10-22 |
| OBEDIAM: Therapeutic Patient Education in Adults Living With Obesity, Diabetes, and Metabolic Disorders Therapeutic patient education - Obesity (BMI>30) | Not applicable | Not yet recruiting | CHU de Quebec-Universite Laval | 42 | 2026-11-01 | 2026-10-22 |
| Stimulating Fat Tissue Storage With Niacin to Reduce Fat Accumulation in the Liver. Niacin (250mg), Placebo Oral Tablet - Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Liver Fibrosis/NASH | Not applicable | Recruiting | Université de Sherbrooke | 36 | 2026-06-22 | 2026-07-02 |
| Non-inferiority Study Comparing Salvage Pelvic Radiotherapy in 25 Fractions (62.5 Gy/25) Versus 20 Fractions (52.5 Gy/20) for Recurrent Prostate Cancer After Surgery. Standard Fractionation Post-Operative Salvage Radiotherapy (25 fractions), Hypofractionated Post-Operative Salvage Radiotherapy (20 fractions), Androgen Deprivation Therapy (ADT) - Reccurent/Metastatic Solid Tumor Disease, Prostate Cancer (Post Prostatectomy) | Not applicable | Recruiting | CHU de Quebec-Universite Laval | 434 | 2026-05-13 | 2026-07-01 |
| Efficacy of Dry Needling in Reducing Pain During Sexual Intercourse Real dry needling, Sham dry needling - Provoked Vestibulodynia | Not applicable | Recruiting | Université de Sherbrooke | 170 | 2026-05-11 | 2026-05-12 |
| Self-questionnaire in Osteoporosis Self-administered questionnaire, Family tree - Osteoporosis | Recruiting | CHU de Quebec-Universite Laval | 58 | 2026-04-01 | 2026-05-08 | |
| Cognitive Behavioral Therapy for Fear of Cancer Recurrence in Women With BRCA1/2 Gene Cognitive-behavioral group therapy - Breast Cancer Susceptibility Gene (BRCA1) Mutation, BRCA2 Mutation | Not applicable | Recruiting | CHU de Quebec-Universite Laval | 250 | 2026-02-01 | 2026-03-31 |
| GMEB-SASS: A Gene-Modified Skin Substitute for RDEB Treatment Genetically Modified Epidermolysis Bullosa Self-Assembled Skin Substitute (GMEB-SASS) - RDEB, Recessive Dystrophic Epidermolysis Bullosa | Phase 1 / Phase 2 | Recruiting | CHU de Quebec-Universite Laval | 9 | 2026-01-07 | 2026-03-18 |
| Immunoglobulins in Multiple Myeloma Patients Receiving a BCMA-Directed T Cell Engager Target trough IgG level of 8-10 g/L, Target trough IgG level 4-6 g/L, No history of recurrent or severe infections and total IgG level higher or equal at 4 g/L - Multiple Myeloma Refractory, Relapsed Multiple Myeloma | Phase 4 | Recruiting | CHU de Quebec-Universite Laval | 80 | 2026-01-05 | 2026-07-22 |
| Immunogenicity and Safety of 2 Doses of Avian Influenza A (H5N1) Vaccine Administered 3 vs. 8 Weeks Apart H5N1 vaccine (Arepanrix), Saline (as a placebo) - H5N1 Influenza, H5N1 Virus | Phase 4 | Active not recruiting | Canadian Immunization Research Network | 312 | 2025-10-14 | 2026-01-16 |
| Personalized vs. Fixed-Activity 177Lu-PSMA-617 Radiopharmaceutical Therapy (PRODIGY-2) 177Lu-PSMA-617 - Metastatic Castrate Resistant Prostate Cancer (mCRPC) | Phase 1 | Recruiting | Jean-Mathieu Beauregard | 60 | 2025-08-15 | 2025-09-09 |
| Activated CHARcoal in Poisoned Patient - Pilot Trial Activated Charcoal, No activated charcoal - Charcoal, Decontamination, Poisoning | Phase 4 | Recruiting | Laval University | 100 | 2025-07-16 | 2026-01-29 |
| Optimizing Patient-centred Outcomes Using Opioid Minimization Strategies: The OPUS Anesthesia Pilot Trial Dexmedetomidine, lidocaine, control group - Anesthesia, Anesthesia Complication | Not applicable | Active not recruiting | CHU de Quebec-Universite Laval | 100 | 2025-07-15 | 2026-07-01 |
| Study to Detect Dendritic Cell Recruitment in Human Retina Dry Age Related Macular Degeneration, Mild Cognitive Impairment (MCI) | Not yet recruiting | MindImmune Therapeutics, Inc. | 15 | 2025-05-01 | 2025-03-12 | |
| Best Practices Fo Early Diagnosis of Cerebral Palsy Implementation group, Standard of care - Cerebral Palsy, Prematurity | Not applicable | Not yet recruiting | St. Justine's Hospital | 2000 | 2025-02-01 | 2024-12-18 |
| Open Lung Protective Extubation Following General Anesthesia Protective "open-lung" extubation, Conventional extubation - Intra-abdominal Surgery, Anesthesia | Not applicable | Recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 270 | 2024-10-08 | 2026-08-17 |
| Support-t Online Training in Youth Living With Type 1 Diabetes Transitioning to Adult Care Support-t - Diabetes Mellitus, Diabetes Mellitus, Type 1 | Not applicable | Active not recruiting | Anne-Sophie Brazeau | 200 | 2024-10-07 | 2026-10-09 |
| Evaluation of Intraocular Pressure Following a Vitreoretinal Surgery Using Goldmann Applanation Tonometry, Icare and Accupen Intraocular pressure measure - Intraocular Pressure | Not applicable | Recruiting | CHU de Quebec-Universite Laval | 67 | 2024-08-05 | 2024-09-26 |
| Paravertebral Block for Mastectomy With Immediate Reconstruction Paravertebral block, Usual analgesia - Postoperative Pain | Not applicable | Recruiting | CHU de Quebec-Universite Laval | 60 | 2024-08-05 | 2026-03-19 |
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Prostatic Neoplasms (16) · Neoplasms (10) · Premature Birth (9) · Breast Neoplasms (7) · Diabetes Mellitus, Type 1 (6) · Fetal Growth Retardation (5) · Pre-Eclampsia (5) · Arthritis, Rheumatoid (4) · Brain Injuries, Traumatic (4) · COVID-19 (4) · Diabetes Mellitus (4) · Insulin Resistance (4) · Obesity (4) · Pain, Postoperative (4) · Radiation Injuries (4)
Dehydroepiandrosterone (3) · Standard of Care (3) · Vitamin D (3) · bicalutamide (3) · 2019-nCoV Vaccine mRNA-1273 (2) · Absorptiometry, Photon (2) · Aspirin (2) · Bariatric Surgery (2) · Cholecalciferol (2) · Dutasteride (2) · Ibuprofen (2) · Lidocaine (2) · Priorix-Tetra vaccine (2) · Saline Solution (2) · Sodium Chloride (2)
Canada (173) · United States (5) · Benin (2) · Brazil (2) · Netherlands (2) · Sweden (2) · Australia (1) · Belgium (1) · Chile (1) · Denmark (1) · France (1) · Germany (1) · Israel (1) · Italy (1) · Jordan (1)
Claudia Gagnon, Dr (4) · Emmanuel Bujold, MD, MSc (4) · Laetitia Michou, MD PhD (4) · Alexis Turgeon, MD MSc FRCPC (3) · Gaston De Serres, MD, PhD (3) · Isabelle Marc, MD, PhD (3) · Claudia Gagnon, MD (2) · Fernand Labrie, MD, PhD (2) · Francois Rousseau, MD MSc FRCPC (2) · Jean-Mathieu Beauregard, MD,MSc,FRCPC (2)
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