187 completed, 50 withdrawn, 45 recruiting, 40 terminated. 172 Not applicable, 54 Phase 2, 37 Phase 4, 30 Phase 1, 10 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Migration of Intraureteral Stents Compared to Conventional Double-J Stents. Intraureteral stent, Conventional Double-J stent - Urologic Diseases, Urological System Complication of Procedure | Not applicable | Withdrawn | University of Louisville | 2027-02-01 | 2022-04-29 | |
| Implementing Stepped Financial and Legal Navigation to Mitigate Financial Toxicity in Adolescent and Young Adult Cancer Patients Oncology Financial and Legal Navigation (OFLN) Oncology Financial and Legal Navigation (OFLN) Stepped: Low Intensity, Oncology Financial and Legal Navigation (OFLN) Standard, Oncology Financial and Legal Navigation (OFLN) Stepped: High-Intensity - Financial Toxicity, Cancer | Not applicable | Not yet recruiting | University of Louisville | 294 | 2027-02-01 | 2026-10-05 |
| TA-65 and Aging Associated Microvascular Dysfunction TA-65, Placebo - Telomere Shortening, Aging | Not applicable | Not yet recruiting | Medical College of Wisconsin | 180 | 2027-01-01 | 2026-05-01 |
| Pomegranate Dietary Supplements in AUD and ALD Pomegranate Dietary Ssupplement - Alcohol Use Disorder, Alcohol-associated Liver Disease | Not yet recruiting | University of Louisville | 144 | 2027-01-01 | 2026-07-24 | |
| MeDex: No Perioperative Dexamethasone in Brain Metastases Withholding perioperative Dexamethasone - Brain Metastases | Not applicable | Recruiting | University of Louisville | 35 | 2026-08-01 | 2026-05-29 |
| Gastric Electrical Stimulation for Abdominal Pain in Patients With Gastroparesis Enterra™ neurostimulator - Gastroparesis, Chronic Abdominal Pain | Not applicable | Not yet recruiting | University of Louisville | 150 | 2026-07-01 | 2026-05-04 |
| Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study Colesevelam, Placebo - PFAS, Environmental Exposures | Phase 2 | Not yet recruiting | University of Rhode Island | 50 | 2026-07-01 | 2026-05-18 |
| GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV Semaglutide (Rybelsus®), Placebo - HIV, Alcohol | Phase 2 | Recruiting | Vanderbilt University Medical Center | 200 | 2026-04-17 | 2026-05-26 |
| Non-invasive Spinal Cord Stimulation and Blood Pressure Regulation After Spinal Cord Injury Spinal Cord Transcutaneous Stimulation - Spinal Cord Injury, Orthostatic Hypertension | Not applicable | Recruiting | University of Louisville | 40 | 2026-04-01 | 2026-04-28 |
| Testing Conversational Agents as a Digital Companion self-directed goal coaching - Autism | Not applicable | Recruiting | Friendi.fi Corporation | 38 | 2026-03-21 | 2026-04-16 |
| Dome-Only Aneurysm Coiling in Severe Aneurysmal Subarachnoid Hemorrhage Aneurysmal Subarachnoid Hemorrhage | Recruiting | University of Louisville | 30 | 2026-03-12 | 2026-05-11 | |
| Comparison of Suzetrigine and Oxycodone for Postoperative Pain After Primary Total Knee Arthroplasty oral suzetrigine, oral Oxycodone - Osteoarthritis (OA) of the Knee | Phase 4 | Enrolling by invitation | University of Louisville | 140 | 2026-02-09 | 2026-05-04 |
| Long-Acting Injectable HIV PrEP PROs Interview and survey to evaluate patient reported outcomes between the two medications. - HIV Pre-exposure Prophylaxis | Not yet recruiting | Anupama Raghuram MD | 128 | 2026-01-15 | 2026-01-30 | |
| Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms Gastroparesis, Idiopathic Gastric Motility Disorder | Recruiting | Johns Hopkins Bloomberg School of Public Health | 150 | 2026-01-13 | 2026-04-03 | |
| Diabetic Cardiomyopathy and Heart Failure Probiotic - Diabetic Cardiomyopathies, Heart Failure | Not applicable | Withdrawn | University of Louisville | 2025-07-01 | 2025-01-31 | |
| Betadine vs Sterile Water for Periurethral Preparation Povidone-Iodine, Sterile water - Catherization, Urinary Tract Infection Bacterial | Phase 4 | Recruiting | University of Louisville | 148 | 2025-06-30 | 2026-05-04 |
| Noninvasive Spinal Stimulation to Restore Hand Function in Children With Spinal Cord Injury Activity based upper extremity training with and without stimulation - Spinal Cord Injury Cervical | Not applicable | Enrolling by invitation | University of Louisville | 10 | 2025-06-13 | 2026-02-18 |
| Saline Versus Balanced Crystalloid in Traumatic Brain Injury Normal Saline (0.9% NaCl), balanced crystalloid - Traumatic Brain Injury (TBI) Patients | Phase 3 | Recruiting | University of Louisville | 600 | 2025-06-01 | 2026-08-26 |
| Osteopathic Manipulative Therapy Effects on Post-Acute Sequelae of COVID-19 (PASC) or Long COVID Osteopathic Manipulative Therapy Long-COVID protocol, Osteopathic Manipulative Therapy NOT Long-COVID treatment protocol - Long-COVID, PASC | Not applicable | Recruiting | University of Louisville | 20 | 2025-05-01 | 2025-03-19 |
| Self-Guided Personalized Treatment for Women Self-guided Personalized Treatment - Disordered Eating | Not applicable | Completed | University of Louisville | 20 | 2025-02-28 | 2026-05-04 |
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Spinal Cord Injuries (26) · Gastroparesis (10) · Lung Neoplasms (10) · Melanoma (10) · Feeding and Eating Disorders (9) · Carcinoma, Non-Small-Cell Lung (8) · Anorexia Nervosa (7) · Breast Neoplasms (7) · Depression (7) · Bulimia Nervosa (6) · Gingival Recession (6) · Asthma (5) · Gastroesophageal Reflux (5) · Head and Neck Neoplasms (5) · Liver Neoplasms (5)
Alloderm (5) · Breathing Exercises (4) · Probiotics (4) · Clindamycin (3) · Doxycycline (3) · Gentamicins (3) · Ketorolac (3) · Metronidazole (3) · Oxaliplatin (3) · Radiation (3) · Radiosurgery (3) · Temozolomide (3) · Vaccines (3) · Zoledronic Acid (3) · beta-Glucans (3)
United States (334) · Canada (9) · Argentina (1) · India (1) · Japan (1) · Mexico (1) · Taiwan (1) · United Kingdom (1)
Henry Greenwell, DMD (11) · Goetz H Kloecker, MD (5) · Henry Greenwell, DMD, MSD (5) · Jiapeng Huang, MD, PhD (5) · Robert Martin, MD, PhD (5) · Rodolfo Zamora, MD (5) · Alexander Ovechkin, MD, PhD (4) · Goetz H Kloecker, MD, MSPH (4) · Rainer Lenhardt, MD (4) · Andrea L Behrman, PT, PhD (3) · Cheri A Levinson, PhD (3) · Craig J McClain, MD (3) · Henry Greenwell, DMD, MS (3) · Henry Parkman, MD (3) · Jason Chesney, MD, PhD (3)
PMID 24842175, PMID 28802811, PMID 29054476, PMID 31811953, PMID 10109801, PMID 10468063, PMID 10727592, PMID 10898180, PMID 10899243, PMID 11166145, PMID 11171742, PMID 11991872, PMID 12186831, PMID 12861145, PMID 12926578, PMID 15273542, PMID 15276398, PMID 15617955, PMID 15663056, PMID 15741979, PMID 15840453, PMID 16314677, PMID 16458626, PMID 16540904, PMID 16647928, PMID 16785355, PMID 16822924, PMID 17054136, PMID 17071309, PMID 17082357, PMID 17216827, PMID 17253510, PMID 17761623, PMID 17852230, PMID 17879694, PMID 17978124, PMID 18206461, PMID 18334033, PMID 18489500, PMID 18595959, PMID 18698279, PMID 1898695, PMID 19160424, PMID 19252451, PMID 19254123, PMID 19285921, PMID 19317999, PMID 19571781, PMID 19588358, PMID 19638912
U01DK074007 (5), U01DK073974 (4), U01DK073975 (4), U01DK073983 (4), U01DK112193 (4), U24DK074008 (4), U01AA021893 (3), U01DK074035 (3), P01AA029543 (2), R01HL150581 (2), 1DP2MH136495-01 (1), 1UG3NS140971-01 (1), 1UH3NS116238-01 (1), 3OT2OD024898-01S5 (1), K23AA018399 (1)