5 completed, 3 unknown, 1 not yet recruiting, 1 recruiting. 5 Not applicable, 2 Phase 4, 1 Phase 1, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 2, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Constipation Drug Induced: new trials by email Literature Review of Constipation Drug Induced trials Research Report on Constipation Drug Induced
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness of Self-administered Acupressure Intervention in Managing Constipation of Adult Psychiatric Out-patient Acupressure - Constipation, Psychiatric Drug Induced Constipation | Not applicable | Not yet recruiting | Hong Kong Metropolitan University | 72 | 2025-07-01 | 2025-06-26 |
| Effectiveness of Self-Administered Acupressure Intervention in Managing Constipation of Adult Psychiatric In-Patient Acupressure, Sham Comparator - Constipation, Psychiatric Drug Induced Constipation | Not applicable | Recruiting | Hong Kong Metropolitan University | 154 | 2025-07-01 | 2025-06-26 |
| Prevention of Constipation in Cancer Patients Abdominal Massage - Constipation Drug Induced | Not applicable | Completed | Can Lafci | 88 | 2025-06-08 | 2026-08-20 |
| Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation Methylnaltrexone Bromide 150 mg Oral Tablet, Methylnaltrexone Bromide 12 MG/0.6 ML Subcutaneous Solution [RELISTOR]_#1, Naloxegol 25 MG Oral Tablet - Constipation Drug Induced | Phase 4 | Completed | University of Missouri-Columbia | 15 | 2020-12-23 | 2024-09-19 |
| The Efficacy of Acupressure in Managing Opioid-induced Constipation Accupressure - Opioid-induced Bowel Dysfunction, Constipation Drug Induced | Not applicable | Unknown | Istanbul Aydın University | 120 | 2020-08-01 | 2021-05-06 |
| Constipation Bundle/Protocol and the Effect of Adherence in the Incidence of Constipation in Critically Ill Patients Implementation of management pharmacological protocol of constipation, Implementation of bundle of prevention and non-pharmacological management - Constipation, Critical Illness | Not applicable | Completed | University of Chile | 66 | 2019-08-01 | 2021-06-08 |
| Study on Quality of Life in Advanced Cancer Patients With Opioid-induced Constipation Treated With Naloxegol Naloxegol - Opioid Use, Constipation Drug Induced | Completed | Fondazione ANT Franco Pannuti ETS | 250 | 2018-09-01 | 2022-02-28 | |
| Naloxegol and Opioid-induced Constipation Naloxegol 25 MG, Placebo pill - Constipation, Constipation Drug Induced | Phase 2 / Phase 3 | Unknown | TriHealth Inc. | 280 | 2017-11-06 | 2022-05-05 |
| Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery Acetaminophen, Gabapentin, Orphenadrine - Colon Cancer, Colon Diverticulosis | Phase 4 | Unknown | University of Illinois College of Medicine at Peoria | 80 | 2017-01-01 | 2017-03-20 |
| Effect of Naloxegol on Gastric, Small Bowel, and Colonic Transit in Healthy Subjects Naloxegol, Codeine, codeine placebo - Constipation Drug Induced | Phase 1 | Completed | Michael Camilleri | 72 | 2016-07-01 | 2017-08-30 |
Constipation (8) · Opioid-Induced Constipation (3) · Agnosia (1) · Colonic Neoplasms (1) · Critical Illness (1) · Diverticulitis, Colonic (1) · Diverticulosis, Colonic (1) · Ileus (1) · Neoplasms (1) · Pain, Postoperative (1) · Rectal Neoplasms (1)
Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Signs and Symptoms, Digestive (9) · Chemically-Induced Disorders (3) · Mental Disorders (3) · Narcotic-Related Disorders (3) · Substance-Related Disorders (3) · Pathologic Processes (2) · Colonic Diseases (1) · Colorectal Neoplasms (1) · Constipation (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Disease Attributes (1) · Diverticular Diseases (1)
naloxegol (4) · Acupressure (2) · Acetaminophen (1) · Bupivacaine (1) · Codeine (1) · Fentanyl (1) · Gabapentin (1) · Hydrocodone (1) · Hydromorphone (1) · Ketamine (1) · Ketorolac (1) · Ketorolac Tromethamine (1) · Lidocaine (1) · Methadone (1) · Morphine (1)
Hong Kong Metropolitan University (2) · Can Lafci (1) · Fondazione ANT Franco Pannuti ETS (1) · Istanbul Aydın University (1) · Michael Camilleri (1) · TriHealth Inc. (1) · University of Chile (1) · University of Illinois College of Medicine at Peoria (1) · University of Missouri-Columbia (1)
United States (4) · Hong Kong (2) · Turkey (Türkiye) (2) · Chile (1) · Italy (1)
Enrico Ruggeri, MD (1) · Michael Camilleri, MD (1) · Scott McCardle, MD (1) · Steven S Tsoraides, MD, MPH (1)
PMID 19135997, PMID 19209273, PMID 19535182, PMID 26150678, PMID 26312011, PMID 34830889, PMID 35257230
UL1TR000135 (1)