23 completed, 13 unknown, 3 not yet recruiting, 2 active not recruiting. 16 Not applicable, 4 Phase 4, 3 Phase 1, 1 Phase 2.
Follow Diverticulosis, Colonic: new trials by email Literature Review of Diverticulosis, Colonic trials Research Report on Diverticulosis, Colonic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Analysis of the Role of the Microbiota in Diverticular Disease Diverticular Disease of Colon, Acute Diverticulitis | Not yet recruiting | Hospital of Navarra | 285 | 2027-06-01 | 2026-09-02 | |
| Non-antibiotic Management in Acute Uncomplicated Diverticulitis Symptomatic treatment (ibuprofen and acetaminophen), Amoxicillin-clavulanate, Ciprofloxacin plus metronidazole - Acute Uncomplicated Diverticulitis | Phase 4 | Withdrawn | Montefiore Medical Center | 2026-07-01 | 2026-08-31 | |
| Percutaneous Drainage Versus Antibiotic Therapy for Acute Diverticulitis With Abscess. Arm 1 (Control Arm) - Percutaneous drainage plus antibiotics: Image-guided (CT or ultrasound) percutaneous drainage performed within 48 hours of randomization with intravenous bro, Arm 2 (Experimental Arm) - Antibiotics alone: Intravenous broad-spectrum antibiotics: piperacillin-tazobactam 4 g/0.5 g q6h (dosage to be adjusted based on renal function) according to the recent lite - Diverticular Disease of Colon | Not applicable | Not yet recruiting | Azienda Sanitaria di Firenze | 50 | 2026-04-01 | 2026-01-20 |
| Post Operative Hospital at Home After Colorectal Surgery virtual Hospital at Home - Colo-rectal Cancer, Colo-rectal Surgery | Not applicable | Not yet recruiting | Nordsjaellands Hospital | 20 | 2025-12-15 | 2025-08-11 |
| Management of Acute Complicated Diverticulitis: An Assessment of Current Practices Acute Complicated Diverticulitis, Colonic Diverticulitis | Completed | Jules Bordet Institute | 208 | 2025-12-01 | 2026-05-22 | |
| Surgical Site Infection Outcomes in Natural Orifice Intracorporeal Anastomosis and Extraction (NICE) Procedure - The NICE Trial Diverticulitis, Surgical Site Infection | Enrolling by invitation | The Methodist Hospital Research Institute | 300 | 2025-04-02 | 2025-05-08 | |
| Effectiveness and Safety of Outpatient Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics Antibiotic, Non antibiotic - Diverticulitis, Colonic | Not applicable | Enrolling by invitation | Monica Mengual Ballester | 282 | 2024-11-01 | 2025-02-25 |
| Colorectal Omics and OfCS Proteoglycans Colorectal resection or stoma closure - Colorectal Cancer, Diverticulitis, Colonic | Recruiting | Claus Anders Bertelsen, PhD, MD | 1000 | 2024-10-08 | 2024-12-30 | |
| Fecal Transplantation in Patients Colonic Diverticulitis Fecal Microbiome, Placebo - Diverticulitis, Colonic, Colon Inflamed | Phase 1 | Unknown | Odense University Hospital | 40 | 2024-04-01 | 2024-04-05 |
| Prospective Evaluation of Quality of Life in Patients With Acute Colonic Diverticular Disease quality of life - Colonic Diverticulitis | Terminated | Niguarda Hospital | 100 | 2023-06-01 | 2024-03-21 | |
| Towards a Tailored Approach for Patients With Acute Diverticulitis and Abscess Formation. A Multicenter Cohort Analysis Conservative treatment with antibiotics and eventual percutaneous image-guided drainage of the abscess - Acute Diverticulitis, Diverticular Diseases | Unknown | University of Cagliari | 400 | 2023-06-01 | 2023-12-05 | |
| Probiotic After Acute Colonic Diverticulitis Probiotic Formula - Diverticulitis, Colonic, Therapy | Unknown | Erasmo Spaziani | 145 | 2023-05-01 | 2023-09-15 | |
| Colon Capsule Endoscopy in Patients With Colonic Diverticulitis colon capsule endoscopy - Diverticulitis, Colonic | Not applicable | Unknown | Odense University Hospital | 120 | 2023-02-01 | 2023-09-11 |
| The Diverticulitis Study Colonic Diverticulitis, Colorectal Cancer | Active not recruiting | University of Aarhus | 250 | 2022-05-01 | 2026-02-06 | |
| Quality of Life and Surgery in Diverticular Disease Sigmoidectomy, Conservative - Diverticulitis Colon, Quality of Life | Recruiting | University of Aarhus | 250 | 2022-04-22 | 2026-05-12 | |
| Safety and Feasibility of ActivSightTM in Human ActivSight - Acute Cholecystitis, Colorectal Cancer | Not applicable | Unknown | Activ Surgical | 67 | 2020-11-17 | 2024-02-21 |
| Outpatient Left Laparoscopic Colectomy Colectomy - Colonic Neoplasms, Colonic Diverticulosis | Completed | Groupe Hospitalier de la Rochelle Ré Aunis | 30 | 2020-11-03 | 2024-02-09 | |
| Management and Evolution of Acute Diverticulitis With Pericolic Free Gas CT imaging - Diverticulitis, Diverticulitis Colon | Completed | Hospital Central de la Defensa Gómez Ulla | 1000 | 2020-06-01 | 2021-06-08 | |
| Prior Abdominal Surgery: A Potential Risk Factor for Colonic Diverticulosis or Diverticulitis comparison - Diverticulosis, Colonic, Abdominal Adhesion | Completed | Assaf-Harofeh Medical Center | 359 | 2020-04-12 | 2022-05-26 | |
| Molecular and Microbiota Signatures Underlying Colonic Diverticular Disease This is an observational study, participants are not assigned an intervention as part of the study. - Diverticular Disease of Colon | Active not recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 150 | 2020-03-05 | 2025-01-08 |
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Diverticulitis, Colonic (27) · Colonic Neoplasms (10) · Diverticulitis (9) · Colorectal Neoplasms (6) · Diverticular Diseases (6) · Rectal Neoplasms (5) · Acute Disease (2) · Crohn Disease (2) · Gastrointestinal Diseases (2) · Inflammatory Bowel Diseases (2) · Agnosia (1) · Anastomotic Leak (1) · Appendicitis (1) · Cholecystitis (1)
Colonic Diseases (48) · Intestinal Diseases (48) · Digestive System Diseases (47) · Gastrointestinal Diseases (46) · Gastroenteritis (33) · Diverticular Diseases (25) · Diverticulitis (20) · Digestive System Neoplasms (16) · Intestinal Neoplasms (16) · Neoplasms (16) · Neoplasms by Site (16) · Gastrointestinal Neoplasms (15) · Rectal Diseases (11) · Colorectal Neoplasms (10)
Anti-Bacterial Agents (3) · Conservative Treatment (3) · Acetaminophen (2) · Ertapenem (2) · Fentanyl (2) · Amoxicillin-Potassium Clavulanate Combination (1) · Bupivacaine (1) · Ciprofloxacin (1) · Colectomy (1) · Colonoscopy (1) · Diet (1) · Endoscopy (1) · Fecal Microbiota Transplantation (1) · Gabapentin (1) · Glutamine (1)
Trinity Health Michigan (3) · Uppsala University (3) · Azienda Sanitaria Locale Napoli 2 Nord (2) · Odense University Hospital (2) · University of Aarhus (2) · Activ Surgical (1) · Assaf-Harofeh Medical Center (1) · Azienda Sanitaria di Firenze (1) · Beijing Friendship Hospital (1) · Centre Hospitalier Universitaire de Nīmes (1) · Cirujanos la Serena (1) · Claus Anders Bertelsen, PhD, MD (1) · Connolly Hospital Blanchardstown (1) · Dr. Falk Pharma GmbH (1) · Emmaus Medical, Inc. (1)
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Robert Cleary, MD (2) · Abbas Chabok, MD, PhD (1) · Alexandre Smirnoff, MD (1) · Bruno Annibale, MD (1) · Christos Kollatos, MD (1) · Claus A Bertelsen, PhD (1) · Daniel B Dumbrava, MBBCh (1) · Doris Henne-Bruns, Prof. Dr. (1) · Eric M Haas, MD (1) · Ferdinand Koeckerling, Prof. Dr. (1) · Gary A Bass, MBBCh MSc MRCS (1) · Giovanni Ferrari, MD (1) · Heikki Huhta, MD, PhD (1) · Helene R Dalby, MD (1)
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