14 unknown. 14 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Unknown 14 |
| Phase 2 | 1 | Unknown 1 |
Follow Brain Injuries: new trials by email Literature Review of Brain Injuries trials Research Report on Brain Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pilot Study of Whole Blood Transfusion for Trauma Brain Injury (TBI) Whole blood transfusion, Blood components transfusion - Traumatic Brain Injury | Phase 3 | Unknown | Oregon Health and Science University | 100 | 2024-08-01 | 2024-04-02 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis Adezunap, Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Role of Combined Therapy of Propranolol and Gabapentin in Paroxysmal Sympathetic Hyperactivity in Traumatic Brain Injury Propranolol , gabapentin - Traumatic Brain Injury | Phase 3 | Unknown | Zagazig University | 90 | 2022-12-01 | 2023-06-13 |
| Sedation of Ventilated Traumatic Brain Injury Patients With Midazolam Alone Versus Combination With Dexmedetomidine or Magnesium Sulfate; Monitored by Ultrasonograghic Optic Nerve Sheath Diameter Ultrasonograghic optic nerve sheath diameter US-ONSD, midazolam, dexmedetomidine - TBI (Traumatic Brain Injury) | Phase 3 | Unknown | Assiut University | 108 | 2022-11-01 | 2022-04-22 |
| Interventions for Convergence Insufficiency in Concussed Children Standard Community Concussion Care (SC), SC plus Simple Convergence Exercises (SC+), SC plus Office-based Vergence/Accommodative Therapy (SC+OBVAT) - Concussion, Convergence Insufficiency | Phase 3 | Unknown | Mitchell Scheiman | 264 | 2021-04-01 | 2020-10-23 |
| Neuromonitoring in Patients During Aortic Valve Replacement Transcranial doppler - Brain Injury | Phase 3 | Unknown | Marija Bozhinovska | 60 | 2016-01-01 | 2016-10-28 |
| Asia Coma Electrical Stimulation (the ACES Trial) Right median nerve stimulation - TBI (Traumatic Brain Injury) | Phase 3 | Unknown | RenJi Hospital | 360 | 2016-01-01 | 2016-01-01 |
| Pre-hospital Administration of Tranexamic Acid for Moderate and Severe Traumatic Brain Injury Tranexamic Acid, Sodium chloride - Brain Injuries, Traumatic | Phase 3 | Unknown | RenJi Hospital | 400 | 2016-01-01 | 2016-01-01 |
| Hyperbaric Oxygen Treatment to Treat Mild Traumatic Brain Injury (mTBI)/Persistent Post-Concussion Syndrome (PPCS) Hyperbaric Oxygen, No Hyperbaric Oxygen - Post-Concussion Syndrome, Traumatic Brain Injury | Phase 3 | Unknown | Louisiana State University Health Sciences Center in New Orleans | 59 | 2014-05-01 | 2017-04-18 |
| PLAY GAME: Post-concussion Syndrome in Youth - Assessing the GABAergic Effects of Melatonin Melatonin, Sugar pill - Post-concussion Syndrome, Post-concussive Symptoms | Phase 2 / Phase 3 | Unknown | University of Calgary | 99 | 2013-09-01 | 2017-04-18 |
| Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation - Sham Comparator - Depressive Episode, Posttraumatic Stress Disorder | Phase 3 | Unknown | INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium | 42 | 2010-10-01 | 2013-04-26 |
| Study to Improve Outcomes for Survivors of Traumatic Brain Injury in Latin America Parenchymal Intracranial pressure monitor, Treatment based on clinical and imaging observations - Traumatic Brain Injury, Brain Injuries | Phase 3 | Unknown | University of Washington | 324 | 2007-07-01 | 2012-11-01 |
| Magnesium Sulfate to Prevent Brain Injury in Premature Infants magnesium sulfate - Brain Injuries, Cerebral Palsy | Phase 3 | Unknown | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 1987-08-01 | 2005-06-24 |
Brain Injuries, Traumatic (11) · Brain Concussion (3) · Agnosia (2) · Chronic Pain (2) · Marijuana Abuse (2) · Multiple Sclerosis (2) · Neuralgia (2) · Pain (2) · Paraplegia (2) · Phantom Limb (2) · Post-Concussion Syndrome (2) · Somatoform Disorders (2) · Stroke (2) · Cerebral Palsy (1)
Brain Diseases (14) · Central Nervous System Diseases (14) · Nervous System Diseases (14) · Trauma, Nervous System (14) · Wounds and Injuries (14) · Craniocerebral Trauma (13) · Mental Disorders (4) · Neurobehavioral Manifestations (4) · Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Cardiovascular Diseases (3) · Cerebrovascular Disorders (3) · Head Injuries, Closed (3)
Magnesium Sulfate (2) · Dexmedetomidine (1) · Exchange Transfusion, Whole Blood (1) · Gabapentin (1) · Hyperbaric Oxygenation (1) · Melatonin (1) · Midazolam (1) · Propranolol (1) · Sodium Chloride (1) · Sugars (1) · Tranexamic Acid (1) · Transcranial Magnetic Stimulation (1) · Ultrasonography, Doppler, Transcranial (1)
Apurano Pharmaceuticals GmbH (2) · RenJi Hospital (2) · Assiut University (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium (1) · Louisiana State University Health Sciences Center in New Orleans (1) · Marija Bozhinovska (1) · Mitchell Scheiman (1) · Oregon Health and Science University (1) · University of Calgary (1) · University of Washington (1) · Zagazig University (1)
United States (4) · Germany (2) · Bolivia (1) · Canada (1) · China (1) · Ecuador (1) · Egypt (1) · Slovenia (1)
Borut Gersak, MD, PhD (1) · Essamedin Negm, MD (1) · Guoyi Gao (1) · Guoyi Gao, MD, PhD (1) · Jiyao Jiang (1) · Junfeng Feng (1) · Karen M Barlow, MB.ChB (1) · Maja Sostaric, MD, PhD (1) · Marija Bozhinovska, MD, MSc (1) · Mark S George, MD (1) · Matej Podbregar, MD, PhD (1) · Mitchell Scheiman, OD, PhD (1) · Paul G Harch, MD (1) · Randall M Chesnut, MD (1) · Thomas E. Wiswell, M.D. (1)
PMID 20554319, PMID 23234472, PMID 24731434, PMID 28693604, PMID 32189664, PMID 32217739, PMID 32772826, PMID 34030698, PMID 37178149, PMID 42104241
R01HD021453 (1), R01NS058302 (1)