8 completed, 3 unknown, 1 not yet recruiting, 1 recruiting. 14 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 8, Unknown 3, Not yet recruiting 1, Recruiting 1, Withdrawn 1 |
| Phase 2 | 3 | Unknown 2, Completed 1 |
Follow Bone Diseases, Infectious: new trials by email Literature Review of Bone Diseases, Infectious trials Research Report on Bone Diseases, Infectious
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prospective, Randomized, Multicenter Clinical Trial of Bisphosphonates Combined With Vancomycin for the Treatment of Cierny-Mader Type I and III Osteomyelitis Bisphosphonates Combined with Vancomycin, Vancomycin - Osteomyelitis (Refractory) | Phase 3 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 280 | 2026-05-01 | 2026-02-27 |
| Continuous Antibiotic Infusion In Children Benzylpenicillin - Infection | Phase 3 | Recruiting | Tampere University Hospital | 150 | 2026-04-21 | 2026-05-08 |
| Oral Vitamin D and Toll Like Receptor in Spondylitis Tuberculosis 400 IU, 5000 IU, 10000 IU - Spondylitis, Tuberculosis | Phase 2 / Phase 3 | Unknown | Hasanuddin University | 37 | 2022-07-01 | 2022-05-17 |
| Corticosteroids as an Additional Treatment for Mastoiditis In Children Dexamethasone, normal saline - Mastoiditis; Acute | Phase 3 | Unknown | ori snapiri | 50 | 2021-04-01 | 2021-04-06 |
| A Pilot Study of MSCs Iufusion and Etanercept to Treat Ankylosing Spondylitis Intravenous infusion of MSCs, Etanercept - Spondylitis, Spondylitis, Ankylosing | Phase 2 / Phase 3 | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 250 | 2016-06-01 | 2016-06-24 |
| Dalbavancin vs Comparator in Pediatric Subjects With Acute Hematogenous Osteomyelitis Dalbavancin, cefazolin, nafcillin, oxacillin or vancomycin - Osteomyelitis | Phase 3 | Withdrawn | Durata Therapeutics International BV (an Affiliate of Actavis, Inc.) | 2016-03-01 | 2016-09-23 | |
| Oral Sodium Fusidate (CEM-102) for the Treatment of Staphylococcal Bone or Joint Infections sodium fusidate - Refractory Bone or Joint Infections | Phase 2 / Phase 3 | Completed | Arrevus Inc. | 30 | 2015-12-01 | 2020-01-30 |
| Study to Demonstrate the Efficacy (Including Inhibition of Structural Damage), Safety and Tolerability up to 2 Years of Secukinumab in Active Psoriatic Arthritis Secukinumab - Psoriatic Arthritis | Phase 3 | Completed | Novartis Pharmaceuticals | 997 | 2015-08-31 | 2020-04-20 |
| Continuing Versus Withdrawing Adalimumab in Maintaining Remission in Non-Radiographic Axial Spondyloarthritis adalimumab, Placebo - Axial Spondyloarthritis | Phase 3 | Completed | AbbVie | 673 | 2013-04-16 | 2018-05-30 |
| Study of Apremilast to Treat Subjects With Active Ankylosing Spondylitis Apremilast tablet 20 mg, Apremilast tablet 30 mg BID, Placebo - Ankylosing Spondyloarthritis | Phase 3 | Completed | Amgen | 490 | 2012-05-02 | 2020-05-12 |
| Ertapenem Sodium (MK-0826) Versus Piperacillin/Tazobactam Sodium for the Treatment of Diabetic Foot Infections in Chinese Adults (MK-0826-061) Ertapenem sodium, Piperacillin/tazobactam sodium, Piperacillin/tazobactam-matching placebo - Infection; Diabetic Foot | Phase 3 | Completed | Merck Sharp & Dohme LLC | 565 | 2011-09-02 | 2018-08-27 |
| Study Evaluating the Safety and Efficacy of a Once-daily Dose of Tigecycline vs Ertapenem in Diabetic Foot Infections (DFI) With a Substudy in Patients With Diabetic Foot Infections Complicated by Osteomyelitis. Tigecycline, Ertapenem - Bacterial Infections, Diabetic Foot | Phase 3 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 1061 | 2007-01-01 | 2010-04-28 |
| Vancomycin Or Trimethoprim/Sulfamethoxazole for Methicillin-resistant Staphylococcus Aureus Osteomyelitis trimethoprim-sulfamethoxazole, vancomycin - Osteomyelitis, Methicillin-resistant Staphylococcus Aureus | Phase 3 | Completed | University of Washington | 2 | 2006-05-01 | 2023-04-11 |
| A Study of the Safety and Efficacy of Golimumab in Subjects With Active Ankylosing Spondylitis golimumab, Golimumab (CNTO 148); placebo - Spondylitis, Ankylosing | Phase 3 | Completed | Centocor, Inc. | 356 | 2005-12-01 | 2013-07-19 |
Osteomyelitis (7) · Spondylitis (6) · Spondylarthritis (4) · Spondylarthropathies (4) · Spondylitis, Ankylosing (4) · Arthritis (3) · Diabetes Complications (2) · Diabetic Foot (2) · Infections (2) · Musculoskeletal Diseases (2) · Spinal Diseases (2) · Ankylosis (1) · Arthritis, Psoriatic (1) · Axial Spondyloarthritis (1) · Bacterial Infections (1)
Bone Diseases (13) · Infections (12) · Musculoskeletal Diseases (12) · Joint Diseases (4) · Spinal Diseases (4) · Ankylosis (3) · Axial Spondyloarthritis (3) · Skin Diseases (3) · Skin and Connective Tissue Diseases (3) · Arthritis (2) · Bacterial Infections and Mycoses (2) · Cardiovascular Diseases (2) · Diabetic Angiopathies (2) · Diabetic Neuropathies (2)
Vancomycin (3) · Ertapenem (2) · Piperacillin, Tazobactam Drug Combination (2) · Adalimumab (1) · Amoxicillin (1) · BID protein, human (1) · Cefazolin (1) · Cholecalciferol (1) · Cloxacillin (1) · Dexamethasone (1) · Etanercept (1) · Fusidic Acid (1) · L 749345 (1) · Nafcillin (1) · Oxacillin (1)
AbbVie (1) · Amgen (1) · Arrevus Inc. (1) · Centocor, Inc. (1) · Durata Therapeutics International BV (an Affiliate of Actavis, Inc.) (1) · Hasanuddin University (1) · Merck Sharp & Dohme LLC (1) · Novartis Pharmaceuticals (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (1) · Tampere University Hospital (1) · University of Washington (1) · Wyeth is now a wholly owned subsidiary of Pfizer (1) · ori snapiri (1)
United States (6) · Canada (4) · Finland (4) · Germany (4) · Austria (3) · China (3) · Estonia (3) · France (3) · Hungary (3) · Netherlands (3) · Russia (3) · Spain (3) · Sweden (3) · United Kingdom (3) · Argentina (2)
Alena Jamdourek, MD (1) · Andi Alfian Zainuddin, MD. Ph.D (1) · Christian Ramers, MD (1) · Firdaus Hamid, MD. Ph.D (1) · Jainal Arifin, MD (1) · Jeanne Chan, PharmD, MPH (1) · Jeanne M Marrazzo, MD, MPH (1) · Lisa Taitsman, MD (1) · M. Bradford Henley, MD (1) · Matthew Golden, MD, MPH (1)
PMID 20506403, PMID 22740380, PMID 23024015, PMID 24439136, PMID 25387477, PMID 26888908, PMID 26932345, PMID 27422890, PMID 27803138, PMID 28031053, PMID 29550766, PMID 29961640, PMID 30412238, PMID 31586420, PMID 33589554, PMID 34330846, PMID 34795065, PMID 38446397, PMID 40973471
2015 (1), 2025 (1)