82 completed, 39 unknown, 21 recruiting, 8 terminated. 42 Not applicable, 20 Phase 2, 16 Phase 4, 14 Phase 3, 4 Phase 1.
Follow Bone Diseases, Infectious: new trials by email Literature Review of Bone Diseases, Infectious trials Research Report on Bone Diseases, Infectious
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| EFFICACY AND SAFETY OF ZOLEDRONATE VERSUS PLACEBO ON PAIN AT WEEK 12 IN PEDIATRIC PATIENTS WITH CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS Zoledronic Acid / Zoledronate 4 MG/100 ML Intravenous Solution, NaCL 0.9% Intravenous Solution - Osteomyelitis Chronic | Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 30 | 2026-09-15 | 2026-06-25 |
| Antibiotic Device for Osteomyelitis of the Extremities Pivotal Trial - Genex With Gentamicin. genex with gentamicin (genex G) - Osteomyelitis | Not applicable | Recruiting | Biocomposites Ltd | 139 | 2026-06-01 | 2026-07-28 |
| Prospective, Randomized, Multicenter Clinical Trial of Bisphosphonates Combined With Vancomycin for the Treatment of Cierny-Mader Type I and III Osteomyelitis Bisphosphonates Combined with Vancomycin, Vancomycin - Osteomyelitis (Refractory) | Phase 3 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 280 | 2026-05-01 | 2026-02-27 |
| Continuous Antibiotic Infusion In Children Benzylpenicillin - Infection | Phase 3 | Recruiting | Tampere University Hospital | 150 | 2026-04-21 | 2026-05-08 |
| Proprio Spine Measurement Tool Intraoperative spinal measurement system - Intervertebral Disc Degeneration, Intervertebral Disc Displacement | Not applicable | Withdrawn | Duke University | 2026-04-20 | 2026-04-23 | |
| Delafloxacin Plasma and Tissue Concentration in Patients With Skin, Soft Tissue, and Bone and Joint Infections. delafloxacin - Soft Tissue Infections, Mediastinitis | Not yet recruiting | IRCCS San Raffaele | 20 | 2026-04-01 | 2026-02-23 | |
| Thoracic Mobility Versus Hip Mobility Exercises to Core Stabilization in Lumbar Spondylitis Group A : Core stabilization exercises (control group), Group B: Thoracic Mobility Exercises (1st experimental group only), Group C: Hip Mobility Exercises (2nd experimental group only) - Lumbar Spondylitis | Not applicable | Completed | Cairo University | 60 | 2026-03-25 | 2026-10-28 |
| Comparison of Oral Antibiotics For Bone Infections of the Leg and Foot Oral Beta-Lactam Antibiotic, Oral Non-Beta-Lactam Antibiotic - Osteomyelitis of Lower Extremities, Osteomyelitis - Foot | Phase 4 | Recruiting | Michael Garron Hospital | 1418 | 2026-02-26 | 2026-03-27 |
| The ACHILLS Trial; Application of Cerament in Heel Infection for Lower Limb Salvage Cerament G, Standard Surgical Managment - Osteomyelitis, Diabetes | Not applicable | Recruiting | Royal College of Surgeons, Ireland | 30 | 2026-01-01 | 2026-07-22 |
| Osteomyelitis Multi-center Prospective Cohort Study Osteomyelitis of Lower Extremities | Not yet recruiting | Southwest Hospital, China | 2000 | 2025-12-10 | 2025-11-26 | |
| Assessment of Non Vascular Risk Factors for Severity of Diabetic Foot Ulcers (DFUs) Diabetic Foot Ulcers, Diabetes Mellitus | Not yet recruiting | Assiut University | 100 | 2025-12-01 | 2025-09-26 | |
| Antibiotic Impregnated Beads in Osteomyelitis Antibiotic loaded calcium sulfate beads, Calcium sulfate beads (sham beads) - Osteomyelitis of the Foot, Antibiotic Impregnated Beads | Phase 4 | Not yet recruiting | University of Arizona | 100 | 2025-09-01 | 2025-07-18 |
| Effects of a Digital Exercise Intervention on Sleep and Physical Activity in Patients With Spondyloarthritis Digital Adapted Physical Activity, Control (Standard treatment) - Spondylarthritis, Spondylarthropathies; Spondylitis, Ankylosing | Not applicable | Not yet recruiting | University Hospital, Grenoble | 100 | 2025-07-01 | 2025-06-29 |
| A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers. STIMULAN VG, Standard of Care - Pressure Ulcer, Stage IV, Osteomyelitis | Phase 2 | Recruiting | Biocomposites Ltd | 60 | 2025-06-15 | 2026-05-06 |
| CERAMENT G as Part of the Surgical Treatment of Osteomyelitis in a Single-Stage Procedure CERAMENT G - Osteomyelitis | Recruiting | BONESUPPORT AB | 128 | 2025-06-02 | 2026-05-04 | |
| Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections Trimethoprim Sulfamethoxazole - Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute | Phase 4 | Recruiting | Indiana University | 100 | 2025-05-20 | 2026-07-29 |
| Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas Aeruginosa Osteomyelitis, Pseudomonas Infections | Recruiting | Centre Hospitalier de Saint-Denis | 300 | 2025-04-11 | 2025-07-09 | |
| Infrared Thermography for Diagnosis of Musculoskeletal Infections High Resolution Thermal Imaging - Musculoskeletal Infection, Septic Arthritis | Recruiting | Sheffield Children's NHS Foundation Trust | 30 | 2025-02-17 | 2026-02-04 | |
| Retention and Re-Engagement in Treatment for Addiction Following Serious Injection Related Infections (RETAIN) RETAIN, Unrelated videos - Opioid Use Disorder, Bloodstream Infection | Not applicable | Completed | Boston Medical Center | 40 | 2025-01-06 | 2026-07-02 |
| Ultrasound Assessment of Neck Muscles and Balance in Male Patients With Ankylosing Spondylitis Ultrasonographic assessment of Cervical Multifidus and Longus Colli Muscle Thickness, Postural Balance and Limit of Stability using the balance platform,Cervical Flexion and Extension Strength - Ankylosing Spondylitis, Balance Assessment | Recruiting | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | 76 | 2025-01-01 | 2025-05-13 |
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Osteomyelitis (95) · Spondylitis (43) · Discitis (23) · Spondylitis, Ankylosing (18) · Diabetic Foot (17) · Arthritis, Infectious (14) · Arthritis (13) · Diabetes Mellitus (12) · Infections (11) · Spondylarthritis (10) · Spondylarthropathies (9) · Intervertebral Disc Displacement (7) · Spinal Diseases (7) · Spinal Stenosis (7)
Bone Diseases (168) · Musculoskeletal Diseases (165) · Infections (159) · Spinal Diseases (60) · Joint Diseases (42) · Pathological Conditions, Signs and Symptoms (40) · Skin and Connective Tissue Diseases (39) · Arthritis (32) · Skin Diseases (32) · Cardiovascular Diseases (26) · Bacterial Infections and Mycoses (25) · Pathologic Processes (25) · Endocrine System Diseases (24) · Spondylitis (23)
Vancomycin (9) · Anti-Bacterial Agents (5) · Ciprofloxacin (5) · Daptomycin (5) · Trimethoprim, Sulfamethoxazole Drug Combination (5) · Cefazolin (4) · Nafcillin (4) · Piperacillin, Tazobactam Drug Combination (4) · Standard of Care (4) · dalbavancin (4) · Amoxicillin-Potassium Clavulanate Combination (3) · Ceftaroline (3) · Cloxacillin (3) · Linezolid (3) · Oxacillin (3)
Assistance Publique - Hôpitaux de Paris (5) · Hospices Civils de Lyon (5) · University Hospital, Montpellier (4) · University of Texas Southwestern Medical Center (4) · Assiut University (3) · Copenhagen University Hospital, Rigshospitalet (3) · AbbVie (2) · Allina Health System (2) · Biocomposites Ltd (2) · Cairo University (2) · Charite University, Berlin, Germany (2) · Groupe Hospitalier Diaconesses Croix Saint-Simon (2) · Indiana University (2) · Istanbul Physical Medicine Rehabilitation Training and Research Hospital (2) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (2)
United States (49) · France (28) · Germany (12) · United Kingdom (11) · Denmark (8) · Italy (8) · Canada (7) · China (7) · Spain (7) · Austria (6) · Russia (6) · Switzerland (6) · Turkey (Türkiye) (6) · Brazil (5) · Israel (5)
Lawrence A Lavery, DPM, MPH (2) · Abass Alavi, MD (1) · Abdullah T Aslan, Dr. (1) · Alena Jamdourek, MD (1) · Alessandra Oliva, MD, PhD (1) · Alexander P Dorr, PhD (1) · Alexandra MT Cardoso, MD (1) · Alistair Wheeler, MD (1) · Allan Bybeck Nielsen, MD (1) · Amanda Gwee, PhD (1) · An de Sutter, PhD (1) · Ana Lucia L Lima, MD PhD (1)
PMID 25468170, PMID 10444737, PMID 10870137, PMID 11074683, PMID 14977679, PMID 15276398, PMID 15564917, PMID 15840453, PMID 1593914, PMID 16019864, PMID 16215330, PMID 16526831, PMID 17700449, PMID 17707385, PMID 18026865, PMID 18057674, PMID 19588358, PMID 19627942, PMID 19730217, PMID 20023348, PMID 20237348, PMID 20506403, PMID 20602122, PMID 21402564, PMID 21824941, PMID 2213777, PMID 22265264, PMID 22488230, PMID 22530208, PMID 22614802, PMID 22740380, PMID 22908174, PMID 23024015, PMID 23040656, PMID 23160432, PMID 23247861, PMID 23284879, PMID 23940419, PMID 24130347, PMID 24421619, PMID 24439136, PMID 24442183, PMID 24671549, PMID 24944860, PMID 25008865, PMID 25277457, PMID 25277543, PMID 25387477, PMID 25618436, PMID 25694111
2023 (2), 2014 (1), 2015 (1), 2019 (1), 2025 (1), K23DA054363 (1), K23HL070058 (1), KL2TR003168 (1), P30CA043703 (1), R01AR046208 (1)