45 completed, 18 unknown, 17 recruiting, 6 not yet recruiting. 23 Not applicable, 12 Phase 2, 12 Phase 4, 8 Phase 3, 3 Phase 1.
Follow Osteomyelitis: new trials by email Literature Review of Osteomyelitis trials Research Report on Osteomyelitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Antibiotic Device for Osteomyelitis of the Extremities Pivotal Trial - Genex With Gentamicin. genex with gentamicin (genex G) - Osteomyelitis | Not applicable | Recruiting | Biocomposites Ltd | 139 | 2026-10-20 | 2026-11-09 |
| EFFICACY AND SAFETY OF ZOLEDRONATE VERSUS PLACEBO ON PAIN AT WEEK 12 IN PEDIATRIC PATIENTS WITH CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS Zoledronic Acid / Zoledronate 4 MG/100 ML Intravenous Solution, NaCL 0.9% Intravenous Solution - Osteomyelitis Chronic | Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 30 | 2026-09-15 | 2026-06-25 |
| Prospective, Randomized, Multicenter Clinical Trial of Bisphosphonates Combined With Vancomycin for the Treatment of Cierny-Mader Type I and III Osteomyelitis Bisphosphonates Combined with Vancomycin, Vancomycin - Osteomyelitis (Refractory) | Phase 3 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 280 | 2026-05-01 | 2026-02-27 |
| Continuous Antibiotic Infusion In Children Benzylpenicillin - Infection | Phase 3 | Recruiting | Tampere University Hospital | 150 | 2026-04-21 | 2026-05-08 |
| Delafloxacin Plasma and Tissue Concentration in Patients With Skin, Soft Tissue, and Bone and Joint Infections. delafloxacin - Soft Tissue Infections, Mediastinitis | Not yet recruiting | IRCCS San Raffaele | 20 | 2026-04-01 | 2026-02-23 | |
| Comparison of Oral Antibiotics For Bone Infections of the Leg and Foot Oral Beta-Lactam Antibiotic, Oral Non-Beta-Lactam Antibiotic - Osteomyelitis of Lower Extremities, Osteomyelitis - Foot | Phase 4 | Recruiting | Michael Garron Hospital | 1418 | 2026-02-26 | 2026-03-27 |
| The ACHILLS Trial; Application of Cerament in Heel Infection for Lower Limb Salvage Cerament G, Standard Surgical Managment - Osteomyelitis, Diabetes | Not applicable | Recruiting | Royal College of Surgeons, Ireland | 30 | 2026-01-01 | 2026-07-22 |
| Osteomyelitis Multi-center Prospective Cohort Study Osteomyelitis of Lower Extremities | Not yet recruiting | Southwest Hospital, China | 2000 | 2025-12-10 | 2025-11-26 | |
| Assessment of Non Vascular Risk Factors for Severity of Diabetic Foot Ulcers (DFUs) Diabetic Foot Ulcers, Diabetes Mellitus | Not yet recruiting | Assiut University | 100 | 2025-12-01 | 2025-09-26 | |
| Antibiotic Impregnated Beads in Osteomyelitis Antibiotic loaded calcium sulfate beads, Calcium sulfate beads (sham beads) - Osteomyelitis of the Foot, Antibiotic Impregnated Beads | Phase 4 | Not yet recruiting | University of Arizona | 100 | 2025-09-01 | 2025-07-18 |
| A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers. STIMULAN VG, Standard of Care - Pressure Ulcer, Stage IV, Osteomyelitis | Phase 2 | Recruiting | Biocomposites Ltd | 60 | 2025-06-15 | 2026-11-10 |
| CERAMENT G as Part of the Surgical Treatment of Osteomyelitis in a Single-Stage Procedure CERAMENT G - Osteomyelitis | Recruiting | BONESUPPORT AB | 128 | 2025-06-02 | 2026-05-04 | |
| Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections Trimethoprim Sulfamethoxazole - Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute | Phase 4 | Recruiting | Indiana University | 100 | 2025-05-20 | 2026-07-29 |
| Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas Aeruginosa Osteomyelitis, Pseudomonas Infections | Recruiting | Centre Hospitalier de Saint-Denis | 300 | 2025-04-11 | 2025-07-09 | |
| Infrared Thermography for Diagnosis of Musculoskeletal Infections High Resolution Thermal Imaging - Musculoskeletal Infection, Septic Arthritis | Recruiting | Sheffield Children's NHS Foundation Trust | 30 | 2025-02-17 | 2026-02-04 | |
| Retention and Re-Engagement in Treatment for Addiction Following Serious Injection Related Infections (RETAIN) RETAIN, Unrelated videos - Opioid Use Disorder, Bloodstream Infection | Not applicable | Completed | Boston Medical Center | 40 | 2025-01-06 | 2026-07-02 |
| Initial Oral Antibiotics for Bone and Joint Infections in Children Oral antibiotic treatment - Osteomyelitis Acute, Septic Arthritis | Recruiting | Copenhagen University Hospital, Rigshospitalet | 100 | 2024-11-15 | 2025-04-09 | |
| Post Market Study of Cerament V/G in Pedal Osteomyelitis cerament V or G - Osteomyelitis - Foot | Not applicable | Completed | Mid and South Essex NHS Foundation Trust | 25 | 2024-10-01 | 2026-08-19 |
| Surgical Treatment of Osteoarticular Infections Using Bioactive Bone Substitute OSTEOMYELITIS SURGICAL TREATMENT WITH LOCAL ANTIBIOTICS AND PEROSSAL - Osteomyelitis, Infections | Not applicable | Unknown | Federal University of São Paulo | 25 | 2024-09-01 | 2024-05-07 |
| Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC) Next Day Clinic - Pneumonia, Syncope | Not applicable | Completed | University of California, Los Angeles | 570 | 2024-07-22 | 2026-05-18 |
Showing 20 of 98. Sign in to see all of them.
Diabetic Foot (17) · Arthritis, Infectious (13) · Diabetes Mellitus (11) · Infections (6) · Bacterial Infections (5) · Mastoiditis (5) · Pneumonia (5) · Sepsis (5) · Soft Tissue Infections (5) · Cellulitis (4) · Fractures, Bone (4) · Bacteremia (3) · Bone Diseases, Infectious (3) · Diabetes Complications (3)
Bone Diseases (98) · Musculoskeletal Diseases (98) · Bone Diseases, Infectious (95) · Infections (92) · Skin and Connective Tissue Diseases (27) · Cardiovascular Diseases (25) · Skin Diseases (23) · Endocrine System Diseases (22) · Skin Ulcer (22) · Vascular Diseases (20) · Leg Ulcer (18) · Pathological Conditions, Signs and Symptoms (18) · Diabetic Angiopathies (16) · Diabetic Neuropathies (16) · Foot Ulcer (16)
Vancomycin (9) · Ciprofloxacin (5) · Daptomycin (5) · Trimethoprim, Sulfamethoxazole Drug Combination (5) · Anti-Bacterial Agents (4) · Cefazolin (4) · Nafcillin (4) · Piperacillin, Tazobactam Drug Combination (4) · Standard of Care (4) · dalbavancin (4) · Amoxicillin-Potassium Clavulanate Combination (3) · Ceftaroline (3) · Cloxacillin (3) · Linezolid (3) · Oxacillin (3)
Hospices Civils de Lyon (5) · University of Texas Southwestern Medical Center (4) · Assistance Publique - Hôpitaux de Paris (3) · Copenhagen University Hospital, Rigshospitalet (3) · Biocomposites Ltd (2) · Indiana University (2) · ASST Ovest Milanese (1) · Academisch Ziekenhuis Maastricht (1) · Adaptive Phage Therapeutics, Inc. (1) · Allergan (1) · Arrevus Inc. (1) · Asan Medical Center (1) · Assiut University (1) · Azienda Ospedaliera San Giovanni Battista (1) · BONESUPPORT AB (1)
United States (34) · France (13) · United Kingdom (7) · Switzerland (5) · China (4) · Denmark (4) · Israel (4) · Italy (4) · Brazil (3) · Canada (3) · Germany (3) · Russia (3) · Spain (3) · Turkey (Türkiye) (3) · Australia (2)
Lawrence A Lavery, DPM, MPH (2) · Abass Alavi, MD (1) · Abdullah T Aslan, Dr. (1) · Alena Jamdourek, MD (1) · Alistair Wheeler, MD (1) · Allan Bybeck Nielsen, MD (1) · Amanda Gwee, PhD (1) · An de Sutter, PhD (1) · Ana Lucia L Lima, MD PhD (1) · Andrew Haynes, MD (1) · Ankur Thapar (1) · Ayse Uysal, MD (1) · Bert Aertgeerts, PhD (1)
PMID 15276398, PMID 15840453, PMID 19588358, PMID 21824941, PMID 22530208, PMID 22908174, PMID 24130347, PMID 24439136, PMID 25277457, PMID 25277543, PMID 25805867, PMID 26160556, PMID 26254472, PMID 26862179, PMID 26888908, PMID 27716201, PMID 28007027, PMID 28866726, PMID 29269559, PMID 29636030, PMID 30038037, PMID 30129109, PMID 30648126, PMID 30664029, PMID 31008367, PMID 31815653, PMID 31914940, PMID 31915048, PMID 33242083, PMID 33660690, PMID 35623048, PMID 36333682, PMID 37072778, PMID 37263683, PMID 39025092, PMID 39040989, PMID 40106180, PMID 41464652, PMID 42286374, PMID 42748421, PMID 4902833, PMID 8948280
2023 (2), 2014 (1), 2019 (1), 2025 (1), K23DA054363 (1), P30CA043703 (1)