725 completed, 192 unknown, 145 recruiting, 67 not yet recruiting. 280 Not applicable, 208 Phase 3, 135 Phase 2, 134 Phase 4, 49 Phase 1.
Follow Spondylitis: new trials by email Literature Review of Spondylitis trials Research Report on Spondylitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Zasocitinib in Adults With Psoriatic Arthritis (LATITUDE PsA NeXt) Placebo, Zasocitinib - Psoriatic Arthritis | Phase 3 | Not yet recruiting | Takeda | 644 | 2027-01-11 | 2026-10-13 |
| Patient-Reported Outcomes Dashboard With Goal Setting to Support Shared Decision-Making in Inflammatory Arthritis Patient-Reported Outcomes Dashboard With Goal Setting - Arthritis, Psoriatic (PsA), Arthritis, Rheumatoid (RA) | Not applicable | Not yet recruiting | Northwestern University | 160 | 2027-01-01 | 2026-10-15 |
| Continued Access to Deucravacitinib for Adult SLE/SjD and Pediatric PsO/PsA Study Completers Deucravacitinib - Systemic Lupus Erythematosus, Sjögren's Disease | Phase 3 | Not yet recruiting | Bristol-Myers Squibb | 2300 | 2026-12-31 | 2026-09-03 |
| Apremilast and Adalimumab in Psoriatic Arthritis Patients Adalimumab, Apremilast - Psoriatic Arthritis, Ultrasound Assessment | Not applicable | Not yet recruiting | Tanta University | 60 | 2026-12-30 | 2026-09-08 |
| Phase 2 Trial of FT2109 for the Treatment of Psoriatic Arthritis FT2109 Dosing Regimen 1, FT2109 Dosing Regimen 2, Matching Placebo - Psoriatic Arthritis (PsA) | Phase 2 | Not yet recruiting | Forward Therapeutics | 210 | 2026-12-01 | 2026-10-09 |
| Effects of Land- and Water-Based Exercise in Axial Spondyloarthritis Land-Based Combined Exercise Program, Aquatic Combined Exercise Program, Home Exercise Program - Axial Spondyloarthritis and Ankylosing Spondylitis | Not applicable | Not yet recruiting | Izmir University of Economics | 50 | 2026-12-01 | 2026-09-22 |
| A Pragmatic Trial of Interleukin-17 Inhibition Versus Janus Kinase Inhibition After Tumor Necrosis Factor-alpha Inhibitor Failure in Axial Spondyloarthritis Secukinumab (IL-17i ), Upadacitinib (JAKi) - Axial Spondyloarthritis (AxSpA) | Phase 4 | Not yet recruiting | The University of Texas Health Science Center, Houston | 40 | 2026-11-01 | 2026-10-14 |
| Posture Exercises in Ankylosing Spondylitis Standard Breathing Exercise Program, Posture-Focused Exercise Program - Ankylosing Spondylitis (AS) | Not applicable | Not yet recruiting | Mustafa Akça | 54 | 2026-11-01 | 2026-10-16 |
| Pain Phenotyping of Rheumatic Diseases - An Observational Study Bedside quantitative sensory testing - Rheumatic Diseases, Lupus Erythematosus, Systemic | Not yet recruiting | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 225 | 2026-10-28 | 2026-10-23 | |
| A Study to Assess the Efficacy, Safety and Tolerability of DDY391 in Participants With Moderate to Severe Psoriatic Arthritis DDY391, Placebo - Moderate to Severe Psoriatic Arthritis | Phase 2 | Recruiting | Novartis Pharmaceuticals | 220 | 2026-10-14 | 2026-10-13 |
| Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic Patients Meibomian Gland Dysfunction, Dry Eye Syndromes | Not yet recruiting | Assiut University | 150 | 2026-10-01 | 2026-09-09 | |
| Evaluation of Serum IL-41 Level in Patients With Ankylosing Spondylitis and Psoriatic Arthritis IL 41 - Ankylosing Spondylitis, Psoriasis | Not yet recruiting | Assiut University | 90 | 2026-10-01 | 2026-07-21 | |
| Postural Biofeedback and Exercise in Axial Spondyloarthritis Standard Exercise Program, Wearable Postural Biofeedback - Axial Spondyloarthritis (AxSpA), Ankylosing Spondylitis (AS) | Not applicable | Not yet recruiting | Istanbul University - Cerrahpasa | 38 | 2026-10-01 | 2026-08-21 |
| Disease Impact and Its Correlation With Disease Activity in Psoriatic Arthritis Psoriatic Arthritis | Not yet recruiting | Assiut University | 80 | 2026-10-01 | 2026-08-31 | |
| A Study to Assess the Safety of Subcutaneous Secukinumab for Treatment in Adult Indian Participants With Axial Spondyloarthritis (axSpA), Ankylosing Spondylitis (AS), and Non-Radiographic Axial Spondyloarthritis (nr-axSpA) Axial Spondyloarthritis, Ankylosing Spondylitis | Not yet recruiting | Novartis Pharmaceuticals | 60 | 2026-09-30 | 2026-07-30 | |
| Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case Series Spine Fracture, Osteoporosis | Not yet recruiting | Diakonie-Klinikum Stuttgart | 23 | 2026-09-20 | 2026-09-29 | |
| Surface Topography and Radiographic Spinal Damage in Radiographic Axial Spondyloarthritis DIERS Formetric 4D surface topography - Axial Spondyloarthritis, Ankylosing Spondylitis | Recruiting | Ankara Etlik City Hospital | 53 | 2026-09-19 | 2026-10-02 | |
| Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research Pericarditis, Tako-TSUBO Cardiomyopathy | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 300 | 2026-09-01 | 2026-08-10 | |
| A Clinical Trial of Antiplatelets in Psoriasis Aspirin, Clopidogrel, Placebo - Psoriasis (PsO), Psoriatic Arthritis (PsA) | Phase 4 | Not yet recruiting | NYU Langone Health | 60 | 2026-09-01 | 2026-08-05 |
| Screening Questionnaires and Musculoskeletal Ultrasound for Early Detection of Spondyloarthritis in IBD Patients DETAIL .IBIS_Q . MSUS - Inflamatory Bowel Disease, Spondylarthritis | Not yet recruiting | Assiut University | 200 | 2026-09-01 | 2026-07-23 |
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Arthritis, Psoriatic (592) · Spondylitis, Ankylosing (517) · Arthritis, Rheumatoid (269) · Spondylarthritis (195) · Axial Spondyloarthritis (176) · Psoriasis (139) · Arthritis (89) · Crohn Disease (67) · Spondylarthropathies (67) · Colitis, Ulcerative (48) · Lupus Erythematosus, Systemic (46) · Motor Activity (32) · Non-Radiographic Axial Spondyloarthritis (32) · Osteoarthritis (31)
Bone Diseases (1298) · Musculoskeletal Diseases (1292) · Spinal Diseases (1291) · Joint Diseases (1252) · Arthritis (1177) · Spondylarthropathies (1078) · Spondylarthritis (1065) · Skin and Connective Tissue Diseases (706) · Ankylosis (643) · Skin Diseases (612) · Skin Diseases, Papulosquamous (602) · Axial Spondyloarthritis (469) · Psoriasis (465) · Immune System Diseases (303)
Etanercept (81) · Adalimumab (75) · secukinumab (58) · Infliximab (52) · golimumab (37) · Methotrexate (34) · apremilast (25) · bimekizumab (21) · tofacitinib (21) · Blood Specimen Collection (19) · Ustekinumab (19) · guselkumab (19) · ixekizumab (18) · Surveys and Questionnaires (16) · Certolizumab Pegol (15)
Novartis Pharmaceuticals (47) · Pfizer (39) · AbbVie (36) · Assistance Publique - Hôpitaux de Paris (28) · Amgen (23) · Janssen Research & Development, LLC (23) · Wyeth is now a wholly owned subsidiary of Pfizer (21) · Charite University, Berlin, Germany (20) · Merck Sharp & Dohme LLC (18) · UCB Biopharma SRL (18) · AbbVie (prior sponsor, Abbott) (14) · Diakonhjemmet Hospital (14) · Assiut University (13) · Eli Lilly and Company (13) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (13)
United States (285) · France (226) · Germany (190) · United Kingdom (145) · Spain (144) · Canada (140) · Turkey (Türkiye) (133) · Poland (132) · China (124) · Czechia (116) · Italy (96) · Russia (95) · Belgium (93) · Hungary (92) · Australia (80)
PMID 40194794, PMID 41807031, PMID 31203228, PMID 37316690, PMID 38446397, PMID 41965705, PMID 42386286, PMID 34618347, PMID 35305260, PMID 38488975, PMID 38488976, PMID 39120849, PMID 30473179, PMID 33722947, PMID 34795065, PMID 35393269, PMID 36178584, PMID 36642439, PMID 36792107, PMID 37906417, PMID 37982966, PMID 38683479, PMID 39120848, PMID 39624020, PMID 40241921, PMID 40875187, PMID 41039829, PMID 19297344, PMID 30018799, PMID 30739254, PMID 31077258, PMID 31112005, PMID 31909868, PMID 31964419, PMID 32006348, PMID 32352653, PMID 32816215, PMID 33227175, PMID 33351179, PMID 34536218, PMID 34773130, PMID 34870800, PMID 35429281, PMID 36058784, PMID 36282526, PMID 36526796, PMID 36754548, PMID 36931693, PMID 36958766, PMID 36995469
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