46 completed, 13 unknown, 6 recruiting, 6 terminated. 42 Not applicable, 10 Phase 4, 2 Phase 3, 1 Early Phase 1.
Follow Arthropathy of Knee: new trials by email Literature Review of Arthropathy of Knee trials Research Report on Arthropathy of Knee
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mako-MORE Registry Mako Robotic-Arm Assisted Arthroplasty - Arthropathy of Knee, Arthropathy of Hip | Recruiting | Stryker Orthopaedics | 950 | 2026-07-13 | 2026-08-18 | |
| Evaluation of 5-year Survival and Clinical Outcomes in Patients Undergoing Total Knee Arthroplasty With a Polyethylene Tibial Component Total knee arthroplasty - Prosthesis Survival, Arthropathy of Knee | Not applicable | Recruiting | Istituto Ortopedico Rizzoli | 78 | 2026-05-13 | 2026-06-23 |
| Economic-demographic Assessment of the Aseptic Mobilization of Knee Prostheses Through the RIPO Registry and Radiographic Analysis of the Case Series From the II Clinic of IOR Aseptic Loosening, Arthropathy of Knee | Completed | Istituto Ortopedico Rizzoli | 31 | 2026-01-13 | 2026-06-18 | |
| MRI Role in Knee Hemophilic Arthopathy MRI, Hemophilia | Not yet recruiting | Assiut University | 95 | 2025-12-01 | 2025-11-18 | |
| Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty NaCl 0.9%, Dexamethasone 4mg - Osteoarthritis, Knee, Knee Pain Chronic | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2025-09-13 | 2026-05-22 |
| Investigating the Effect of Dronabinol on Post-surgical Pain Dronabinol 5mg Cap, Non-active comparator - Knee Replacement, Arthropathy of Knee | Early Phase 1 | Withdrawn | New York State Psychiatric Institute | 2025-09-01 | 2023-11-13 | |
| How Many Dexamethasone Doses Should Be Given Perioperatively? Dexamethasone IV, Dexamethasone IV+Oral, Dexamethasone IV+Oral 2 Day - Arthropathy of Knee | Phase 4 | Enrolling by invitation | Mayo Clinic | 339 | 2025-03-25 | 2026-02-06 |
| Comparison of Postoperative Pain in Primary Cemented Total Knee Arthroplasty With or Without Drain Redon drain - Postoperative Pain, Arthropathy of Knee | Not applicable | Completed | Hospital Universitario Reina Sofia de Cordoba | 60 | 2025-01-01 | 2025-09-16 |
| Total Versus Robotic Assisted Unicompartmental Knee Replacement MAKO™ Partial Knee Arthroplasty, Triathlon (Stryker) Total Knee Arthroplasty - Osteo Arthritis Knee, Arthritis Knee | Not applicable | Recruiting | NHS Lothian | 159 | 2024-08-26 | 2026-09-23 |
| Preliminary Muscle Contraction in the Rehabilitation and Prevention of Degenerative Pain in the Locomotor System Standard advice and Preliminary muscle contraction, Standard advice - Pain, Back, Pain, Neck | Not applicable | Unknown | Medical University of Sofia | 216 | 2024-05-14 | 2024-05-16 |
| Incidence and Risk Factors for Post-Anesthetic Morphine Titration in Recovery Room After Hip and Knee Arthroplasties IV morphine administered during the PACU stay - Arthropathy of Hip, Arthropathy of Knee | Active not recruiting | Hôpital Privé Sévigné | 300 | 2024-04-01 | 2025-02-18 | |
| Fascia Iliaca Compartment Block and IPACK Block in Total Knee Arthroplasty no peripheral block, Fascia Iliaca Compartment Block, iPACK Block - Arthropathy of Knee, Analgesia | Completed | Ankara Ataturk Sanatorium Training and Research Hospital | 120 | 2024-04-01 | 2024-12-12 | |
| Nirvana Super Pro Supplementation in Orthopedic Surgery Patients Supplementation with Nirvana Super Pro Liquid Supplements, Non-Supplementation Group - Arthropathy of Knee, Arthropathy of Hip | Not applicable | Unknown | Nirvana Water Sciences Corp | 100 | 2024-02-21 | 2024-03-27 |
| Comparison of Two Different Regional Analgesia Techniques for Patients Undergoing Total Knee Arthroplasty Selective tibial nerve block, IPACK block - Analgesia, Arthropathy of Knee | Not applicable | Unknown | Centre Hospitalier Universitaire Vaudois | 100 | 2024-02-08 | 2024-02-09 |
| The Effect of Virtual Reality Goggles on Pain, Anxiety and Sleep in Patients Undergoing Total Knee Arthroplasty Virtual Reality Group - Arthropathy of Knee | Not applicable | Completed | Sennur Kula Şahin | 94 | 2024-01-05 | 2026-11-09 |
| Weight Change and the Risk of Chronic Pain Following Hip and Knee Arthroplasties Weight gain, Weight loss, Weight unchanged - Persistent Postsurgical Pain, Arthritis Knee | Unknown | Bispebjerg Hospital | 6400 | 2023-11-01 | 2023-09-06 | |
| Comparative Effect of Mechanical and Functional Alignment in Bilateral Total Knee Arthroplasty on Ankle Alignment Mechanical alignment, Functional alignment - Arthropathy of Knee | Not applicable | Completed | Department of Medical Services Ministry of Public Health of Thailand | 20 | 2023-10-01 | 2024-11-21 |
| The Effect of Whole-Body Vibration Treatment Before Total Knee Arthroplasty Whole body vibration, Sham-Whole body vibration - Whole-body Vibration, Arthropathy of Knee | Not applicable | Completed | Gazi University | 29 | 2023-08-01 | 2025-07-11 |
| A Multi-Component Weight Loss Intervention to Improve Outcomes of Total Knee Replacement Multi-Component Weight Loss Intervention - Arthropathy of Knee, Obesity | Not applicable | Completed | University of Kansas Medical Center | 24 | 2023-05-01 | 2025-09-17 |
| Late-initiated Blood Flow Restricted Rehabilitation Exercises After Total Knee Replacement Blood flow restricted low-load resistance exercise - Osteoarthritis, Knee, Arthropathy of Knee | Not applicable | Terminated | University of Aarhus | 56 | 2023-04-12 | 2024-09-23 |
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Osteoarthritis, Knee (14) · Pain, Postoperative (10) · Agnosia (4) · Arthralgia (3) · Musculoskeletal Diseases (3) · Obesity (3) · Osteoarthritis (3) · Acute Pain (2) · Hemophilia A (2) · Knee Injuries (2) · Opioid-Related Disorders (2) · Osteonecrosis (2) · Pain (2) · Urinary Retention (2) · Arthritis (1)
Pathological Conditions, Signs and Symptoms (23) · Joint Diseases (21) · Musculoskeletal Diseases (20) · Signs and Symptoms (19) · Rheumatic Diseases (17) · Arthritis (16) · Neurologic Manifestations (16) · Osteoarthritis (14) · Pain (14) · Pathologic Processes (14) · Postoperative Complications (12) · Nervous System Diseases (4) · Neurobehavioral Manifestations (4) · Nutrition Disorders (4) · Nutritional and Metabolic Diseases (4)
Sodium Chloride (4) · Arthroplasty, Replacement, Knee (3) · Ropivacaine (2) · Tranexamic Acid (2) · Anesthesia, Spinal (1) · Anesthetics, General (1) · Blood Transfusion (1) · Capsules (1) · Cefazolin (1) · Control Groups (1) · Dexamethasone (1) · Dexmedetomidine (1) · Dietary Supplements (1) · Dronabinol (1) · Educational Status (1)
Istituto Ortopedico Rizzoli (3) · Stryker Orthopaedics (3) · Assiut University (2) · Duke University (2) · Mayo Clinic (2) · Peking University People's Hospital (2) · Seoul National University Hospital (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Ankara Ataturk Sanatorium Training and Research Hospital (1) · AppliedVR Inc. (1) · Benaroya Research Institute (1) · Beth Israel Deaconess Medical Center (1) · Bispebjerg Hospital (1) · Brigham and Women's Hospital (1) · Centre Hospitalier Universitaire Vaudois (1)
United States (26) · Turkey (Türkiye) (8) · Italy (4) · South Korea (4) · Spain (4) · Switzerland (3) · Denmark (2) · Netherlands (2) · Poland (2) · United Kingdom (2) · Canada (1) · China (1) · France (1) · Pakistan (1) · Portugal (1)
Jianhao Lin, MD (2) · Ahmet Fayik Oner, Prof. (1) · Anette Larsson, PhD (1) · Antonia Chen, MD/MBA (1) · Antonia Pierobon, Dr. (1) · Arthur Malkani, MD (1) · Arzu Erden (1) · Assen R Aleksiev (1) · Barbara Smith, PhD (1) · Beyza Yazgan (1) · Bradley H Lee, MD (1) · C. Lowry Barnes, MD (1) · Candice St. Pierre, Ph.D. (1) · Cesare Stagni, MD (1)
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R21AG083667 (1), R44DA049640 (1)