55 completed. 55 Phase 2, 7 Phase 3, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 55 | Completed 55 |
| Phase 3 | 7 | Completed 7 |
| Phase 1 | 3 | Completed 3 |
Follow Angina Pectoris: new trials by email Literature Review of Angina Pectoris trials Research Report on Angina Pectoris
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Impact of Vericiguat on Microvascular Function in Patients With Documented Vasospastic Angina Pectoris Vericiguat - Vasospastic Angina | Phase 2 | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 57 | 2025-02-10 | 2026-07-29 |
| Epicardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment (The EXACT Trial) AdVEGFXC1 - Coronary Artery Disease, Ischemia | Phase 1 / Phase 2 | Completed | XyloCor Therapeutics, Inc. | 41 | 2020-01-24 | 2024-01-30 |
| Adenovirus Vascular Endothelial Growth Factor D (AdvVEGF-D) Therapy for Treatment of Refractory Angina Pectoris AdvVEGF-D, Control Rx - Refractory Angina Pectoris, Gene Transfer | Phase 2 | Completed | Kuopio University Hospital | 63 | 2019-10-19 | 2025-01-13 |
| Precision Medicine With Zibotentan in Microvascular Angina Zibotentan, Placebo oral tablet - Microvascular Angina | Phase 2 | Completed | NHS Greater Glasgow and Clyde | 225 | 2019-10-18 | 2023-08-04 |
| The Randomized OPTIMAL-ACT Trial Unfractionated heparin - Coronary Artery Disease, Ischemic Heart Disease | Phase 2 | Completed | Mayo Clinic | 180 | 2019-02-08 | 2023-04-04 |
| Crushed Ticagrelor Versus Eptifibatide Bolus + Clopidogrel Ticagrelor, Eptifibatide, Clopidogrel - Acute Coronary Syndrome, Angina, Unstable | Phase 2 | Completed | University of Alabama at Birmingham | 100 | 2016-11-01 | 2020-05-04 |
| Treadmill Cardiovascular Safety Study of Erenumab (AMG 334) Erenumab, Placebo - Stable Angina | Phase 2 | Completed | Amgen | 89 | 2015-11-23 | 2018-08-24 |
| Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina Beetroot Juice - Cardiovascular Diseases | Phase 2 | Completed | Queen Mary University of London | 300 | 2015-11-02 | 2025-06-11 |
| A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome Acetylsalicylic acid, Rivaroxaban, Clopidogrel - Acute Coronary Syndrome | Phase 2 | Completed | Janssen Research & Development, LLC | 3037 | 2015-04-20 | 2017-12-26 |
| Ranolazine Among Unrevascularized Chronic Stable Angina Patients Ranolazine, Sugar pill - Angina | Phase 2 | Completed | North Florida Foundation for Research and Education | 50 | 2014-09-01 | 2019-08-22 |
| Microvascular Assessment of Ranolazine in Non-Obstructive Atherosclerosis (MARINA) Ranolazine, Placebo - Microvascular Angina | Phase 2 | Completed | Emory University | 26 | 2014-09-01 | 2019-05-21 |
| Safety and Efficacy of CMX-2043 for Protection of the Heart and Kidneys in Subjects Undergoing Coronary Angiography CMX-2043, Placebo comparator - Non STEMI, Unstable Angina | Phase 2 | Completed | Ischemix, LLC | 361 | 2014-06-01 | 2016-02-23 |
| Liraglutide to Improve corONary Haemodynamics During Exercise streSS Liraglutide, Placebo - Ischaemic Heart Disease, Coronary Heart Disease | Phase 2 | Completed | King's College London | 26 | 2014-01-01 | 2015-05-20 |
| The Effects of Inorganic Nitrate on Cardiac Muscle in Angina Sodium Nitrate, Placebo - Chronic Stable Angina | Phase 2 | Completed | University of Aberdeen | 70 | 2012-10-01 | 2015-11-05 |
| Intracardiac CD133+ Cells in Patients With No-option Resistant Angina intramyocardial injection (electromechanical mapping based), Placebo - Stable Angina | Phase 2 | Completed | Medical University of Silesia | 31 | 2012-06-01 | 2017-09-28 |
| Shortened Aggrastat® Versus Integrilin in Percutaneous Coronary Intervention Short Tirofiban, Eptifibatide, Long Tirofiban - Myocardial Infarction, Acute Coronary Syndromes | Phase 2 | Completed | Medicure | 535 | 2012-04-01 | 2021-05-13 |
| Optimal Dose of Acetylsalicylic Acid After Coronary Artery Bypass Grafting Acetylsalicylic acid - Coronary Artery Bypass Surgery, Stable Angina | Phase 2 / Phase 3 | Completed | Karolinska University Hospital | 45 | 2011-12-01 | 2018-03-08 |
| Evaluate the Efficacy and Safety of Pletaal (Cilostazol) in Subjects With Vasospastic Angina Placebo - Variant Angina | Phase 2 | Completed | Korea Otsuka Pharmaceutical Co., Ltd. | 50 | 2011-10-01 | 2012-07-16 |
| Effect of Oxygen During Percutaneous Coronary Intervention for Pain Relief Nasal oxygen, Regular nasal air - Angina | Phase 2 | Completed | Region Skane | 300 | 2011-07-01 | 2012-08-10 |
| Comparison of Drug Eluting Balloon and Drug Eluting Stent Drug eluting balloon + Bare metal stent, drug eluting stent (Zotarolimus-eluting stent) - Coronary Artery Disease, Stable Angina | Phase 2 | Completed | Seoul National University Bundang Hospital | 180 | 2011-04-01 | 2015-06-12 |
Showing 20 of 55. Sign in to see all of them.
Angina, Stable (18) · Angina, Unstable (17) · Coronary Artery Disease (17) · Myocardial Infarction (14) · Myocardial Ischemia (8) · Acute Coronary Syndrome (6) · Chest Pain (4) · Heart Failure (4) · Non-ST Elevated Myocardial Infarction (4) · Cardiovascular Diseases (3) · Coronary Disease (3) · Microvascular Angina (3) · Angina Pectoris, Variant (2) · Atherosclerosis (2)
Vascular Diseases (55) · Heart Diseases (54) · Neurologic Manifestations (54) · Pain (54) · Pathological Conditions, Signs and Symptoms (54) · Signs and Symptoms (54) · Cardiovascular Diseases (52) · Chest Pain (50) · Myocardial Ischemia (47) · Pathologic Processes (22) · Infarction (18) · Ischemia (18) · Necrosis (18) · Arterial Occlusive Diseases (17)
Clopidogrel (5) · Aspirin (4) · Ticagrelor (4) · Eptifibatide (3) · Abciximab (2) · Heparin (2) · Influenza Vaccines (2) · Ranolazine (2) · STA 2 (2) · Tirofiban (2) · 1-(1-(3-((6-chloronaphthalen-2-yl)sulfonyl)-2-hydroxypropanoyl)piperidin-4-yl)tetrahydropyrimidin-2(1H)-one (1) · Adenosine (1) · Amlodipine (1) · Atorvastatin (1) · Capsules (1)
AstraZeneca (2) · Shahid Beheshti University of Medical Sciences (2) · Sinphar Pharmaceutical Co., Ltd (2) · ARCA Biopharma, Inc. (1) · Ablynx, a Sanofi company (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Amgen (1) · Anthera Pharmaceuticals (1) · Antwerp Cardiovascular Institute Middelheim (1) · Biopure Corporation (1) · Boehringer Ingelheim (1) · Cardium Therapeutics (1) · Celgene (1) · CellPraxis Bioengenharia Ltda. (1) · Corewell Health East (1)
United States (22) · Belgium (9) · United Kingdom (9) · Netherlands (8) · Canada (6) · Germany (6) · Poland (5) · Russia (5) · Czechia (4) · Denmark (4) · South Korea (4) · Sweden (4) · Brazil (3) · Bulgaria (3) · Hungary (3)
Ali Eskandari, MD (2) · Chuen-Den Tseng, MD, Ph.D (2) · Hossein Vakili, M.D. (2) · Maryam Keshtkar-Jahromi, M.D.; M.P.H. (2) · Seyed Mostafa Razavi, MD (2) · Sharareh Gholamin, MD (2) · Alan S Lader, PhD (1) · Amrita Ahluwalia, PhD (1) · Andrew A Wolff, MD, FACC (1) · Annapoorna S Kini, MD MRCP (1) · Anthony A Bavry, MD, MPH (1) · Boris Nasseri, MD (1) · Christof Stamm, MD (1) · David Leibowitz, MD (1)
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2008 (1), 2014 (1), 2015 (1), U01HL087318 (1)