65 completed, 24 unknown, 8 terminated, 3 recruiting. 107 Phase 3, 15 Phase 2.
Follow Angina Pectoris: new trials by email Literature Review of Angina Pectoris trials Research Report on Angina Pectoris
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nebivolol ANOCA Treatment Randomized Trial Nevibolol, Placebo - ANOCA - Angina With Non-obstructive Coronary Arteries, Coronary Microvascular Dysfunction (CMD) | Phase 3 | Not yet recruiting | Spanish Society of Cardiology | 150 | 2025-04-01 | 2025-01-01 |
| Personalized Evaluation of Susptected Myocardial Ischemia Clinical Likelihood (CL) Model-Based Diagnostic Strategy, Standard of care treatment - Chronic Coronary Syndrome, Angina Pectoris | Phase 3 | Enrolling by invitation | Gødstrup Hospital | 2000 | 2024-11-20 | 2025-12-19 |
| Efficacy of Endothelin Receptor Antagonism in Coronary Artery Spasm Endothelin Receptor Antagonist, Placebo control - Coronary Spasm | Phase 2 / Phase 3 | Enrolling by invitation | Radboud University Medical Center | 100 | 2024-11-11 | 2024-11-18 |
| Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries Amlodipine, Nebivolol, Placebo - Angina Pectoris, Microvascular Angina | Phase 2 / Phase 3 | Recruiting | Stanford University | 150 | 2024-10-10 | 2024-11-27 |
| Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis Colchicine 0.5 MG, Ticagrelor 90mg, Aspirin 75-300mg - Stroke, Stroke, Ischemic | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 2800 | 2023-05-17 | 2025-09-08 |
| Prasugrel Or Ticagrelor De-escalation in NSTE-ACS De-escalation to ticagrelor 60 mg at day 30, De-escalation to prasugrel 5 mg at day 30, Switch to ticagrelor 60 mg at day 45 - Non ST Segment Elevation Acute Coronary Syndrome, Non-ST-Segment Elevation Myocardial Infarction (NSTEMI) | Phase 3 | Unknown | Collegium Medicum w Bydgoszczy | 50 | 2023-04-01 | 2023-03-22 |
| Ad5FGF-4 In Patients With Refractory Angina Due to Myocardial Ischemia Ad5FGF-4, Placebo - Angina, Stable | Phase 3 | Unknown | Angionetics Inc. | 160 | 2023-01-01 | 2022-07-19 |
| Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19 Prednisolone, Losartan - COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle | Phase 3 | Active not recruiting | Valentina Puentmann | 279 | 2022-12-12 | 2025-12-09 |
| Evaluation of Safety and Efficacy of Two Ticagrelor-based De-escalation Antiplatelet Strategies in Acute Coronary Syndrome Ticagrelor 90mg, Ticagrelor 60mg, Aspirin - STEMI, NSTEMI | Phase 3 | Unknown | Collegium Medicum w Bydgoszczy | 4500 | 2022-02-07 | 2023-04-21 |
| Dapagliflozin Effects on Coronary Calcium and Epicardial Fat Assessed by Cardiotomography Dapagliflozin 10Mg Tab, Placebo - Diabete Type 2, Unstable Angina | Phase 3 | Completed | Hilda Elizabeth Macías Cervantes | 54 | 2021-06-21 | 2023-08-21 |
| Allopurinol in Patients With Refractory Angina to Improve Ischemic Symptoms Allopurinol 300 MG, Placebo oral tablet - Refractory Angina | Phase 2 / Phase 3 | Unknown | Ministry of Health, Brazil | 40 | 2021-03-03 | 2021-02-24 |
| Rhodiola Rosea for Coronary Microvascular Disease Rhodiola Rosea Capsules, Placebo - Coronary Microvascular Disease | Phase 2 / Phase 3 | Unknown | Qilu Hospital of Shandong University | 114 | 2020-01-01 | 2020-01-06 |
| Efficacy of Diltiazem to Improve Coronary Microvascular Dysfunction: a Randomized Clinical Trial Diltiazem Hydrochloride, Placebo - Microvascular Angina, Coronary Vasospasm | Phase 3 | Active not recruiting | Radboud University Medical Center | 85 | 2019-10-25 | 2023-03-30 |
| Outcome Research to Confirm the Anti-anginal Effect of T89 in Patients With Stable Angina T89 capsule, Placebo capsule - Chronic Stable Angina Pectoris | Phase 3 | Recruiting | Tasly Pharmaceuticals, Inc. | 765 | 2019-08-01 | 2025-04-09 |
| Vaccination Against Influenza to Prevent Cardiovascular Events After Acute Coronary Syndromes Double Dose Quadrivalent Influenza Vaccine, Standard Dose Quadrivalent Influenza Vaccine - Acute Coronary Syndrome | Phase 3 | Completed | Hospital Israelita Albert Einstein | 1801 | 2019-07-19 | 2022-08-31 |
| Vitamin E and N-acetylcysteine for Preventing Contrast-Induced Acute Kidney Injury After Coronary Artery Catheterization Vitamin E, N-acetyl cysteine, Placebo oral capsule - Coronary Artery Disease, Coronary Artery Angiography | Phase 3 | Unknown | Rajaie Cardiovascular Medical and Research Center | 1000 | 2018-11-01 | 2018-11-30 |
| Trimetazidine in Myocardial Injury After Percutaneous Coronary Intervention in Patients With Angina and Diabetes trimetazidine, Placebo Oral Tablet - Diabetes Mellitus, Angina, Unstable | Phase 3 | Unknown | University of Sao Paulo General Hospital | 120 | 2018-10-01 | 2018-10-24 |
| Effect of External Counter Pulsation on Coronary Artery Disease External Counter Pulsation - Stable Chronic Angina, Coronary Artery Disease | Phase 3 | Unknown | Eighth Affiliated Hospital, Sun Yat-sen University | 380 | 2018-06-08 | 2017-12-13 |
| The Effect Of Ticagrelor On Saphenous Vein Graft Patency In Patients Undergoing Coronary Artery Bypass Grafting Surgery Ticagrelor, Placebo - Coronary Artery Disease, Stable Angina | Phase 3 | Unknown | J.M. ten Berg | 487 | 2015-03-01 | 2020-04-27 |
| Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy Eleclazine, Placebo - Hypertrophic Cardiomyopathy | Phase 2 / Phase 3 | Terminated | Gilead Sciences | 172 | 2015-02-05 | 2018-09-24 |
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Angina, Unstable (43) · Myocardial Infarction (31) · Coronary Artery Disease (29) · Angina, Stable (28) · Acute Coronary Syndrome (27) · Myocardial Ischemia (25) · Heart Diseases (13) · Cardiovascular Diseases (11) · Coronary Disease (11) · Non-ST Elevated Myocardial Infarction (6) · Microvascular Angina (5) · Angina Pectoris, Variant (4) · Atherosclerosis (4) · Chest Pain (4)
Vascular Diseases (106) · Pathological Conditions, Signs and Symptoms (105) · Neurologic Manifestations (104) · Pain (104) · Signs and Symptoms (104) · Chest Pain (100) · Cardiovascular Diseases (96) · Heart Diseases (94) · Myocardial Ischemia (82) · Pathologic Processes (38) · Infarction (35) · Necrosis (35) · Ischemia (33) · Arterial Occlusive Diseases (30)
Clopidogrel (8) · Aspirin (6) · Ticagrelor (6) · Ranolazine (5) · Adenosine (3) · Enoxaparin (3) · Influenza Vaccines (3) · Abciximab (2) · Angioplasty, Balloon, Coronary (2) · Cilostazol (2) · Coronary Artery Bypass (2) · Oxygen (2) · Percutaneous Coronary Intervention (2) · Prasugrel Hydrochloride (2) · Rivaroxaban (2)
National Heart, Lung, and Blood Institute (NHLBI) (5) · Cardium Therapeutics (4) · Gilead Sciences (4) · Sanofi (3) · Assistance Publique - Hôpitaux de Paris (2) · Centocor, Inc. (2) · Collegium Medicum w Bydgoszczy (2) · Karolinska Institutet (2) · Korea Otsuka Pharmaceutical Co., Ltd. (2) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (2) · Ministry of Health, Brazil (2) · Organon and Co (2) · Pfizer (2) · Radboud University Medical Center (2) · Shahid Beheshti University of Medical Sciences (2)
United States (27) · Canada (14) · Germany (13) · Netherlands (13) · Brazil (10) · Italy (10) · Russia (10) · Poland (9) · United Kingdom (9) · France (8) · Sweden (8) · China (7) · Australia (6) · Belgium (6) · Israel (6)
Ali Eskandari, MD (2) · Hossein Vakili, M.D. (2) · Maryam Keshtkar-Jahromi, M.D.; M.P.H. (2) · Neville Suskin, MBChB, MSc (2) · Paul Foster, MD (2) · Robert L. Rolleri, Pharm.D. (2) · Seyed Mostafa Razavi, MD (2) · Sharareh Gholamin, MD (2) · Adolph Hutter (1) · Alfredo Zuppiroli, MD (1) · Andras Komocsi, MD PhD (1) · Andrew Wallace (1) · Benjamin Terrier, MD, PhD (1)
PMID 17825712, PMID 35224730, PMID 11239408, PMID 15238590, PMID 16304073, PMID 16537663, PMID 16875985, PMID 17010793, PMID 17124018, PMID 17299194, PMID 17368152, PMID 17456819, PMID 17637939, PMID 18056903, PMID 18196350, PMID 18331634, PMID 18376001, PMID 18440330, PMID 18502300, PMID 18765432, PMID 19022155, PMID 19033002, PMID 19061694, PMID 19136486, PMID 19171852, PMID 19270315, PMID 19298914, PMID 19332455, PMID 19349325, PMID 19371824, PMID 19389561, PMID 19460609, PMID 19463332, PMID 19463378, PMID 19608137, PMID 19628125, PMID 19699861, PMID 19717846, PMID 19825809, PMID 19843899, PMID 19853332, PMID 20026777, PMID 20031731, PMID 20060578, PMID 20079528, PMID 20118151, PMID 20124123, PMID 20142447, PMID 20194880, PMID 20298924
2018 (2), 1RC2HL101458-01 (1), 2005 (1), 2014 (1), R01HL031025 (1), R01HL042428 (1), R01HL050839 (1), R01HL076808 (1), U01HL038610 (1), U01HL064829 (1), U01HL077821 (1), U01HL077822 (1), U01HL077823 (1), U01HL077826 (1)