7 completed, 1 recruiting, 1 unknown. 9 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 7, Recruiting 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Analgesics, Opioid: new trials by email Literature Review of Analgesics, Opioid trials Research Report on Analgesics, Opioid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimizing Pain Treatment in Children On Mechanical Ventilation Acetaminophen, Ketorolac, Placebo - Mechanical Ventilation, Pediatric Acute Respiratory Failure | Phase 3 | Recruiting | Weill Medical College of Cornell University | 644 | 2025-12-29 | 2026-07-30 |
| Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study Dexmedetomidine 0.004 MG/ML [Precedex], Opioids - Analgesia, Analgesics, Opioid | Phase 3 | Completed | St. Justine's Hospital | 42 | 2022-03-15 | 2023-05-09 |
| Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery Acetaminophen, Gabapentin, Lidocaine 1% Injectable Solution, Dexmedetomidine, Ketamine, Dexamethasone, Ondansetron - Anesthesia, General Anesthesia | Phase 3 | Unknown | University of Saskatchewan | 60 | 2021-05-15 | 2023-12-20 |
| Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy Acetaminophen, gabapentin, Acetaminophen, Ketamine , Lidocaine , Dexmedetomidine - Anesthesia, General Anesthesia | Phase 3 | Completed | University of Saskatchewan | 50 | 2017-10-15 | 2021-08-10 |
| Buprenorphine Transdermal Patches in Arthroscopic Rotator Cuff Repair Buprenorphine, Placebo Patch, Multimodal Oral Scheme - Rotator Cuff Tear, Rotator Cuff Injury | Phase 2 / Phase 3 | Completed | Hospital Italiano de Buenos Aires | 50 | 2016-09-22 | 2021-04-08 |
| A Study of OROS Hydromorphone HCL vs Morphine in Cancer Pain Patients. OROS hydromorphone HCL ; Morphine sulfate - Pain, Analgesics, Opioid | Phase 3 | Completed | Alza Corporation, DE, USA | 202 | 2010-04-27 | |
| A Repeated-Dose Evaluation of Use of a Pain Relieving Drug and Safety of OROS Hydromorphone HCI in Patients With Chronic Cancer Pain OROS Hydromorphone HCI - Analgesics, Opioid, Pain | Phase 3 | Completed | Alza Corporation, DE, USA | 463 | 2010-04-27 | |
| Safety and Tolerability of Long-term Administration of OROS Hydromorphone HCI (Slow Release) in Cancer Pain OROS hydromorphone HCI (slow release) - Analgesics, Opioid, Pain | Phase 3 | Completed | Alza Corporation, DE, USA | 68 | 2010-04-27 | |
| Safety and Tolerability of Long-Term Administration of Hydromorphone HCI CR (Controlled Release) OROS hydromorphone HCI CR - Pain, Analgesics, Opioid | Phase 3 | Completed | Alza Corporation, DE, USA | 388 | 2010-04-27 |
Pain (4) · Agnosia (3) · Cancer Pain (1) · Chronic Pain (1) · Pathologic Processes (1) · Postoperative Complications (1) · Respiratory Insufficiency (1) · Rotator Cuff Injuries (1) · Sleep Apnea Syndromes (1)
Pathological Conditions, Signs and Symptoms (8) · Neurologic Manifestations (7) · Signs and Symptoms (7) · Nervous System Diseases (4) · Neurobehavioral Manifestations (3) · Perceptual Disorders (3) · Apnea (1) · Dyssomnias (1) · Respiration Disorders (1) · Respiratory Tract Diseases (1) · Rupture (1) · Shoulder Injuries (1) · Sleep Disorders, Intrinsic (1) · Sleep Wake Disorders (1) · Tendon Injuries (1)
Acetaminophen (3) · Dexmedetomidine (3) · Dexamethasone (2) · Gabapentin (2) · Ketamine (2) · Lidocaine (2) · Ondansetron (2) · Sevoflurane (2) · Analgesics, Opioid (1) · Buprenorphine (1) · Fentanyl (1) · Ketorolac (1) · Magnesium Sulfate (1) · Morphine (1) · Sufentanil (1)
Alza Corporation, DE, USA (4) · University of Saskatchewan (2) · Hospital Italiano de Buenos Aires (1) · St. Justine's Hospital (1) · Weill Medical College of Cornell University (1)
Canada (3) · Argentina (1) · United States (1)
Chani Traube, MD (1) · Christina Lamontagne (1) · Jon Gamble, MD (1)
U01HD116260 (1)