329 completed, 123 unknown, 75 recruiting, 40 not yet recruiting. 386 Not applicable, 43 Phase 4, 31 Phase 2, 22 Phase 3, 20 Phase 1.
Follow Rupture: new trials by email Literature Review of Rupture trials Research Report on Rupture
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Estradiol Supplementation and Rotator Cuff Repair Transdermal estrogen, Rotator Cuff Repair Surgery - Rotator Cuff Tears, Rotator Cuff Injuries | Phase 2 | Not yet recruiting | University of Utah | 58 | 2028-03-01 | 2026-03-19 |
| Effectiveness of Non-surgical Management in Rotator Cuff Calcific Tendinopathy (THE EFFECT TRIAL) Exercise Therapy, Extracorporeal Shockwave Therapy, Ultrasound-Guided Percutaneous Irrigation - Rotator Cuff Tendinosis, Rotator Cuff Injuries | Not applicable | Suspended | University of Valencia | 116 | 2028-01-01 | 2026-06-26 |
| Does MI Have a Therapeutic Role in Arthroscopic Rotator Cuff Repair? Motor Imagery, Physical Therapy - Rotator Cuff Tears, Motor Imagery | Not applicable | Suspended | Alanya Alaaddin Keykubat University | 36 | 2027-09-15 | 2026-10-28 |
| Impact of BPC-157 on Recovery Following Rotator Cuff Repair Surgery BPC-157, Sham (No Treatment) - Rotator Cuff Tear | Phase 1 | Not yet recruiting | University of Arkansas | 30 | 2027-01-01 | 2026-09-03 |
| Decellularized Human Placental Extracellular Matrix Tissue for Rotator Cuff Repair Augmentation Rotator Cuff Repair with Allograft Patch, Rotator Cuff Repair with No Augmentation - Rotator Cuff Tear | Not applicable | Not yet recruiting | Columbia University | 120 | 2027-01-01 | 2026-09-10 |
| Tapestry Rotator Cuff Repair PMCF Tapestry Biointegrative Implant - Rotator Cuff Tears, Rotator Cuff Injuries | Suspended | Zimmer Biomet | 170 | 2026-12-28 | 2025-11-21 | |
| Aortic Size and Height Indices in Abdominal Aortic Aneurysms Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm, Ruptured | Not yet recruiting | Tecnologico de Monterrey | 2000 | 2026-11-01 | 2026-10-26 | |
| Effects of Cervicothoracic Mobilization in Patients With Supraspinatus Tendinitis Cervicothoracic Junction Mobilization, Traditional Physical Therapy - Rotator Cuff Tendonitis | Not applicable | Recruiting | Riphah International University | 62 | 2026-10-29 | 2026-11-06 |
| Ultrasound and Shear Wave Elastography for Assessment of the Quality of Rotator Cuff Muscles Rotator Cuff Injuries, Rotator Cuff Tear | Not yet recruiting | Assiut University | 70 | 2026-10-01 | 2026-09-23 | |
| Remote App-based Rehabilitation After Rotator Cuff Repair Telerehabilitation, Conventional home exercise program - Rotator Cuff Tear, Telemedecine | Not applicable | Not yet recruiting | Hanoi Medical University | 102 | 2026-10-01 | 2026-09-22 |
| Repeated Injections of Adipose-derived Stem Cells in Rotator Cuff Tears Adipose derived stem cell injection, Placebo - Rotator Cuff Tears, Rotator Cuff Injuries | Phase 1 / Phase 2 | Not yet recruiting | University of Southern Denmark | 30 | 2026-10-01 | 2026-09-30 |
| Smallest Worthwhile Effect of Rotator Cuff Repair and Supervised Exercise Rotator Cuff Tears (RCTs) | Not yet recruiting | Kırklareli University | 104 | 2026-10-01 | 2026-08-21 | |
| Percutaneous Tenotomy Versus Radiofrequency Ablation for Rotator Cuff Tear - Related Pain. Percutaneous tenotomy of the long head of the biceps tendon (LHBT), Ultrasound guided radiofrequency ablation of the suprascapular nerve - Rotator Cuff Tear, Pain Management | Not applicable | Not yet recruiting | Centre of Postgraduate Medical Education | 60 | 2026-10-01 | 2026-10-16 |
| Arthroscopic Rotator Cuff Repair With Long Head of Biceps Transposition and Acellular Dermal Matrix Augmentation for Large to Massive Incompletely Repairable Rotator Cuff Tears Rotator Cuff Repair, Long Head of the Biceps Tendon Transposition, Acellular Dermal Matrix (Allograft) Augmentation - Rotator Cuff Tears, Rotator Cuff Injuries | Not applicable | Recruiting | Tam Anh Research Institute | 40 | 2026-09-16 | 2026-10-19 |
| Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines Synovial Fluid withdrawal at the preoperative clinic visit, Platelet-Rich Plasma (PRP) preparation and injection, Synovial fluid withdrawal at the time of surgery - Posttraumatic Osteoarthritis, Anterior Cruciate Ligament (ACL) Rupture | Not applicable | Not yet recruiting | Rush University Medical Center | 99 | 2026-09-01 | 2026-06-18 |
| Effect of a Posterior Shoulder Pillow on Pain and Sleep Quality After Rotator Cuff Repair Posterior Shoulder Pillow, Conventional Rehabilitation Protocol - Rotator Cuff Injuries, Postoperative Pain | Not applicable | Not yet recruiting | Peking University Third Hospital | 126 | 2026-09-01 | 2026-09-16 |
| The Effectiveness of High-intensity Laser Therapy After Arthroscopic Shoulder Rotator Cuff Repair. High intensity laser therapy, Sham laser therapy - Rotator Cuff Tears | Not applicable | Not yet recruiting | Istituto Ortopedico Rizzoli | 46 | 2026-09-01 | 2026-05-05 |
| Biomarkers to Predict Rotator Cuff Repair Healing on Postoperative MRI MRN - Rotator Cuff Tears | Not applicable | Recruiting | Joseph W. Galvin | 60 | 2026-09-01 | 2026-08-24 |
| Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block - Pain, Postoperative, Rebound Pain | Phase 4 | Recruiting | Seoul National University Hospital | 92 | 2026-08-25 | 2026-09-29 |
| Achilles Non-SNIS REGENETEN REGENETEN - Complete Mid-portion Achilles Rupture | Enrolling by invitation | OrthoCarolina Research Institute, Inc. | 50 | 2026-08-03 | 2026-10-09 |
Showing 20 of 671. Sign in to see all of them.
Rotator Cuff Injuries (580) · Shoulder Pain (76) · Shoulder Impingement Syndrome (38) · Pain (24) · Pain, Postoperative (22) · Motor Activity (17) · Shoulder Injuries (17) · Aortic Rupture (16) · Tendinopathy (16) · Bursitis (13) · Rotator Cuff Tear Arthropathy (11) · Anterior Cruciate Ligament Injuries (10) · Wounds and Injuries (10) · Aneurysm (8)
Wounds and Injuries (661) · Tendon Injuries (576) · Shoulder Injuries (563) · Pathological Conditions, Signs and Symptoms (152) · Musculoskeletal Diseases (135) · Signs and Symptoms (131) · Neurologic Manifestations (129) · Joint Diseases (120) · Pain (97) · Arthralgia (75) · Pathologic Processes (50) · Cardiovascular Diseases (36) · Vascular Diseases (36) · Nervous System Diseases (31)
Physical Therapy Modalities (22) · Exercise (13) · Bupivacaine (11) · Ropivacaine (9) · Saline Solution (9) · Exercise Therapy (7) · Injections (7) · Dexamethasone (6) · Rehabilitation (6) · Tranexamic Acid (6) · Adrenal Cortex Hormones (5) · Ketorolac (5) · Lidocaine (5) · Standard of Care (5) · Acetaminophen (4)
Peking University Third Hospital (14) · Zimmer Biomet (10) · Istanbul University - Cerrahpasa (9) · Rothman Institute Orthopaedics (9) · Hacettepe University (8) · Seoul National University Hospital (8) · Smith & Nephew, Inc. (8) · Cairo University (7) · Chuncheon Sacred Heart Hospital (7) · Istanbul Medipol University Hospital (6) · Istituto Ortopedico Rizzoli (6) · National Taiwan University Hospital (6) · Panam Clinic (6) · Riphah International University (6) · Schulthess Klinik (6)
United States (170) · Turkey (Türkiye) (80) · Canada (47) · France (32) · South Korea (30) · China (25) · Italy (25) · Switzerland (25) · Taiwan (21) · Brazil (15) · Egypt (15) · Spain (15) · Denmark (13) · United Kingdom (12) · Norway (10)
Jung-Taek Hwang, MD, PhD (4) · Peter Lapner, MD (4) · Guoqing Cui (3) · Joseph Lombardi, MD (3) · Kathleen Derwin, PhD (3) · Burak Menek, PhD (2) · Catherine J Fedorka, MD (2) · Chris H. Jo, M.D., Ph.D (2) · Chunyan Jiang (2) · Felipe Ponce-Fuentes, MSc (2) · Hassan Achakri (2) · Ivan Wong, MD (2)
PMID 24880194, PMID 12449254, PMID 28446376, PMID 28932752, PMID 30134883, PMID 32527698, PMID 32975624, PMID 33935152, PMID 8020238, PMID 10633896, PMID 10797220, PMID 10976589, PMID 11304107, PMID 11347400, PMID 11679610, PMID 11688948, PMID 11912097, PMID 12629425, PMID 12683565, PMID 12724676, PMID 12851579, PMID 14564276, PMID 15069134, PMID 15262646, PMID 15769790, PMID 15788347, PMID 15862727, PMID 16012501, PMID 16231283, PMID 16325080, PMID 16551396, PMID 16607589, PMID 16799776, PMID 17084305, PMID 17179786, PMID 17188907, PMID 17210425, PMID 17264144, PMID 17399623, PMID 17700327, PMID 17986401, PMID 17993287, PMID 18363045, PMID 18753683, PMID 19171279, PMID 19181972, PMID 19190053, PMID 19219713, PMID 19487518, PMID 19574063
2019 (4), 2009 (1), 2015 (1), 2017 (1), 2023 (1), K23AR059199 (1), R01AR051026 (1), R01AR074989 (1), U34AR069201 (1)