15 completed, 7 not yet recruiting, 6 unknown, 4 recruiting. 19 Not applicable, 7 Phase 3, 1 Early Phase 1, 1 Phase 2, 1 Phase 4.
Follow Traumatic Injury: new trials by email Literature Review of Traumatic Injury trials Research Report on Traumatic Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CHW-Enhanced Trauma Recovery CHW support - Traumatic Injury, Posttraumatic Stress Disorder | Not applicable | Not yet recruiting | Medical University of South Carolina | 100 | 2027-01-01 | 2026-10-01 |
| Transforming Trauma Care Trauma Resilience and Recovery Program Portal 2.0 (TRRP 2.0) - Post-Traumatic Stress Disorder (PTSD), Depression | Not applicable | Not yet recruiting | Medical University of South Carolina | 300 | 2026-12-01 | 2026-09-21 |
| Ketogenic Feeding for Muscle Preservation After Trauma Ketogenic feeding, Standard feeding - Traumatic Injury | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 20 | 2026-11-15 | 2026-09-18 |
| Opioid Analgesia Impacts on Neurological Development Fracture, Scoliosis Idiopathic Adolescent | Not yet recruiting | University of Nottingham | 30 | 2026-09-01 | 2026-10-02 | |
| Weighted Blankets for Pain and Anxiety in Adult Trauma Patients Weighted Blanket, Standard Hospital Blanket - Traumatic Injury, Acute Pain | Not applicable | Not yet recruiting | University of Texas at Austin | 50 | 2026-09-01 | 2026-09-03 |
| Early Intervention to Prevent Development of PTSD in Burn Survivors and Their Caregivers Promotion of Emotional Disclosure for Burns (PoED-B), minimally Enhanced Usual Care control (mEUC) - Posttraumatic Stress Disorder, Burns | Not applicable | Not yet recruiting | University of Southern California | 44 | 2026-08-01 | 2026-06-18 |
| Pilot Feasibility Trial of a Peer Support Program for Trauma Survivors Cross-continuum Peer Support Program - Traumatic Injury, Burns | Not applicable | Not yet recruiting | Sunnybrook Health Sciences Centre | 49 | 2026-01-01 | 2025-12-10 |
| Advancing Discussions Using a Video-based Support Tool About End-of-life Care Video conversation aid, Usual Care - Traumatic Injury | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 270 | 2025-03-17 | 2025-03-30 |
| Pediatric and Caregiver Traumatic Stress Intervention (PACTS) Caregiver Counseling for Childhood Traumatic Injury, Standard of Care for Childhood Traumatic Injury - Traumatic Injury | Not applicable | Completed | Wake Forest University Health Sciences | 13 | 2024-11-26 | 2026-10-13 |
| Sustainable Elite Football Overuse Injury, Traumatic Injury | Enrolling by invitation | Linnaeus University | 400 | 2024-11-25 | 2026-01-08 | |
| Use of 81 vs 325mg of ASA in Treatment of BCVI Acetylsalicylic Acid - Carotid Artery Injuries, Traumatic Injury | Early Phase 1 | Unknown | London Health Sciences Centre | 40 | 2024-06-01 | 2024-04-25 |
| Trauma BPE Prolonged Exposure Therapy for Injured Individuals Admitted to a Level I Trauma Center Treatment as Usual, Brief Prolonged Exposure Therapy - Traumatic Injury, PTSD | Not applicable | Recruiting | Baylor Research Institute | 300 | 2024-02-28 | 2026-10-15 |
| Prehospital Analgesia INtervention Trial (PAIN) Ketamine Hydrochloride, Fentanyl Citrate - Traumatic Injury | Phase 3 | Recruiting | Jason Sperry | 994 | 2023-11-27 | 2026-03-09 |
| Near-Infrared Imaging for Perfusion Assessment of Traumatic Soft Tissue and Skeletal Injuries Near-infrared fluorescence imaging of perfusion - Perfusion, Traumatic Injury | Not applicable | Unknown | Leiden University Medical Center | 120 | 2023-11-13 | 2024-03-20 |
| Enantyum® IV Versus Piroxen® IM in Emergency Pain Management Dexketoprofen, Piroxicam - Traumatic Injury | Phase 3 | Unknown | Riadh Boukef | 300 | 2023-07-15 | 2024-05-08 |
| Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study ) BE1116, Placebo - Traumatic Injury | Phase 3 | Terminated | CSL Behring | 1366 | 2023-03-28 | 2025-12-10 |
| A Psychosocial Transitional Group to Improve Adaptation, Coping and Mental Health Outcomes Following Trauma Supportive Expressive Group Therapy - Musculoskeletal Injury, Traumatic Injury | Not applicable | Completed | Sunnybrook Health Sciences Centre | 55 | 2023-01-23 | 2024-09-19 |
| DSUVIA Early Evaluation of Pain Trial Sufentanil 30 MCG Sublingual Tablet, standard care pain treatment - Traumatic Injury | Phase 3 | Completed | Frank Guyette | 150 | 2022-08-05 | 2025-04-30 |
| Ketamine Low dOse Evaluation on Morphine Consumption in Traumatic Patient Administration of drug - Traumatic Injury | Phase 3 | Completed | Assistance Publique Hopitaux De Marseille | 140 | 2022-08-05 | 2026-02-04 |
| Evaluation of Trauma Center-Based Intervention for Adolescent Traumatic Injury Survivors TRRP, Enhanced Usual Care - Traumatic Injury, Technology | Not applicable | Active not recruiting | Medical University of South Carolina | 300 | 2022-07-01 | 2026-09-23 |
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Wounds and Injuries (37) · Stress Disorders, Post-Traumatic (6) · Depression (3) · Substance-Related Disorders (3) · Acute Pain (2) · Agnosia (2) · Burns (2) · Emergencies (2) · Muscular Atrophy (2) · Pain (2) · Soft Tissue Injuries (2) · Tendon Injuries (2) · Accidental Injuries (1) · Adolescent Behavior (1) · Alcohol Drinking (1)
Pathological Conditions, Signs and Symptoms (11) · Mental Disorders (9) · Signs and Symptoms (8) · Nervous System Diseases (7) · Neurologic Manifestations (7) · Behavior (5) · Pathologic Processes (5) · Stress Disorders, Traumatic (5) · Trauma and Stressor Related Disorders (5) · Chemically-Induced Disorders (4) · Behavioral Symptoms (3) · Brain Diseases (3) · Central Nervous System Diseases (3) · Trauma, Nervous System (3) · Atrophy (2)
Standard of Care (3) · Administration, Inhalation (1) · Administration, Sublingual (1) · Aspirin (1) · Dronabinol (1) · Enoxaparin (1) · Epoetin Alfa (1) · Fentanyl (1) · Galactose (1) · Ketamine (1) · Methoxyflurane (1) · Piroxicam (1) · Sodium Chloride (1) · Sufentanil (1) · Therapeutics (1)
Medical University of South Carolina (3) · University of Pittsburgh (3) · Jason Sperry (2) · Sunnybrook Health Sciences Centre (2) · Assistance Publique Hopitaux De Marseille (1) · Australian and New Zealand Intensive Care Research Centre (1) · Baylor Research Institute (1) · CSL Behring (1) · Cairo University (1) · Centre Hospitalier Universitaire Saint Pierre (1) · CommonSpirit Health (1) · Direction Centrale du Service de Santé des Armées (1) · Fondation Santé des Étudiants de France (1) · Frank Guyette (1) · Indiana University (1)
United States (19) · France (4) · Canada (3) · Australia (2) · Belgium (2) · United Kingdom (2) · Egypt (1) · Finland (1) · Germany (1) · Iraq (1) · Ireland (1) · Netherlands (1) · New Zealand (1) · Saudi Arabia (1) · Slovenia (1)
J. Peter Rubin, MD (2) · Jason Sperry, MD (2) · Tatiana Davidson, PhD (2) · Ann Marie Warren, PhD (1) · Associate Professor Craig French (1) · Basima Gh Ali, MSc (1) · Ben Marson, MB BCh BSc PhD FRCS (1) · Carlos Brown, MD (1) · Claire J Swartwood, PharmD (1) · Elizabeth Shilling, PhD (1) · Hassan Ahmed (1) · Jason L Sperry, MD (1) · Jason Smith, MD (1) · Jason Sperry, MD, MPH (1)
PMID 26452709, PMID 29302336, PMID 32178232, PMID 33978907, PMID 35727343, PMID 37792797, PMID 38531812, PMID 39919020, PMID 40271704, PMID 41782923, PMID 42026625, PMID 42150044, PMID 42310772, PMID 42314159
K23MH141296 (1), R01HD102336 (1), R21MD021589 (1)