7 completed, 1 active not recruiting, 1 recruiting, 1 unknown. 11 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 7, Active not recruiting 1, Recruiting 1, Unknown 1, Withdrawn 1 |
Follow Toxemia: new trials by email Literature Review of Toxemia trials Research Report on Toxemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cardiovascular Protection After Preeclampsia With Enalapril Enalapril, Standard treatment - Preeclampsia, Hypertensive Disorder of Pregnancy | Phase 3 | Recruiting | Women and Infants Hospital of Rhode Island | 60 | 2026-01-01 | 2026-08-06 |
| Calcium Aspirin Multiple Micronutrients (CAMMS) to Reduce Preterm Birth Calcium aspirin multiple micronutrients, Iron-folic Acid - Preterm Labor, Small for Gestational Age at Delivery | Phase 3 | Withdrawn | Johns Hopkins Bloomberg School of Public Health | 2024-04-01 | 2024-04-23 | |
| Intensive Postpartum Antihypertensive Treatment Nifedipine ER - Hypertensive Disorder of Pregnancy | Phase 3 | Active not recruiting | Medical College of Wisconsin | 60 | 2023-09-01 | 2026-07-20 |
| Temocillin vs Meropenem for the Targeted Treatment of Bacteraemia Resistant to Third Gen Cephalosporins Temocillin, Meropenem - Bacteremia | Phase 3 | Completed | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 334 | 2020-12-15 | 2026-01-23 |
| Triple Therapy in Septic Shock Patients vitamin c - thiamine- hydrocortisone - Septic Shock, Sepsis | Phase 3 | Completed | Air Force Specialized Hospital, Cairo, Egypt | 94 | 2019-08-01 | 2021-01-26 |
| Early Versus Late BCG Vaccination in HIV-1 Exposed Infants in Uganda in Uganda BCG at birth, Control arm: Delayed BCG - Severe Illness, Septicaemia | Phase 3 | Completed | Makerere University | 4500 | 2016-07-01 | 2025-03-04 |
| Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock Ceftriaxone, Piperacillin tazobactam, Norepinephrine - Severe Septic Syndrome (Severe Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 398 | 2016-05-09 | 2026-08-24 |
| A Study to Compare the Immunogenicity of GSK Biologicals' 10Pn-PD-DiT 4-dose Presentation to the Licensed 1-dose Synflorix™ (10Pn-PD-DiT) Vaccine When Co-administered With DTPw-combination Vaccine in Healthy Infants Pneumococcal vaccine GSK1024850A (10Pn-PD-DiT) vaccine (4-dose presentation), Pneumococcal vaccine GSK1024850A (10Pn-PD-DiT) vaccine (1-dose presentation), DTPw-HBV/Hib - Infections, Streptococcal | Phase 3 | Completed | GlaxoSmithKline | 320 | 2015-06-11 | 2018-08-02 |
| In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II C1-esterase inhibitor, Endotoxin - Innate Immune Response, Endotoxemia | Phase 3 | Completed | Radboud University Medical Center | 20 | 2013-09-01 | 2014-12-02 |
| Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines in Papua New Guinean Children Prevenar 13 and Synflorix - Pneumonia, Meningitis | Phase 3 | Unknown | Papua New Guinea Institute of Medical Research | 200 | 2011-11-01 | 2014-03-21 |
| The Effects of Metformin on Pregnancy and Miscarriage Rates in Polycystic Ovary Syndrome (PCOS) metformin - Polycystic Ovary Syndrome, Miscarriage | Phase 3 | Completed | University of Oulu | 326 | 2002-08-01 | 2010-02-23 |
Sepsis (4) · Meningitis (2) · Otitis Media (2) · Pneumonia (2) · Shock, Septic (2) · Abortion, Spontaneous (1) · Bacteremia (1) · Diabetes, Gestational (1) · Diarrhea (1) · Disease (1) · Endotoxemia (1) · Haemophilus Infections (1) · Hypertension (1) · Hypertension, Pregnancy-Induced (1)
Infections (11) · Pathological Conditions, Signs and Symptoms (7) · Pathologic Processes (6) · Systemic Inflammatory Response Syndrome (5) · Inflammation (4) · Female Urogenital Diseases and Pregnancy Complications (3) · Urogenital Diseases (3) · Bacterial Infections (2) · Bacterial Infections and Mycoses (2) · Ear Diseases (2) · Lung Diseases (2) · Nervous System Diseases (2) · Neuroinflammatory Diseases (2) · Otitis (2) · Otorhinolaryngologic Diseases (2)
PHiD-CV vaccine (2) · 10-valent pneumococcal conjugate vaccine (1) · 13-valent pneumococcal vaccine (1) · Ceftriaxone (1) · Complement C1 Inhibitor Protein (1) · Enalapril (1) · Endotoxins (1) · Hydrocortisone (1) · Meropenem (1) · Metformin (1) · Norepinephrine (1) · Piperacillin, Tazobactam Drug Combination (1) · Vaccines (1) · let-363 protein, C elegans (1) · temocillin (1)
Air Force Specialized Hospital, Cairo, Egypt (1) · Assistance Publique - Hôpitaux de Paris (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · GlaxoSmithKline (1) · Johns Hopkins Bloomberg School of Public Health (1) · Makerere University (1) · Medical College of Wisconsin (1) · Papua New Guinea Institute of Medical Research (1) · Radboud University Medical Center (1) · University of Oulu (1) · Women and Infants Hospital of Rhode Island (1)
United States (2) · Bangladesh (1) · Egypt (1) · Finland (1) · France (1) · Netherlands (1) · Papua New Guinea (1) · Spain (1) · Uganda (1)
Abdelrhman Hussein (1) · Alisse Hauspurg, MD (1) · Deborah Lehmann, MSc (1) · Halvor Sommerfelt, MD, PhD (1) · Hans Hoeven, Prof (1) · Jean Humphrey, ScD (1) · Laure C Morin-Papunen, PhD (1) · Peter Richmond, MD (1) · Romain Jouffroy, MD (1) · Victoria Nankabirwa, MD, MPH, PhD (1) · William S Pomat, PhD (1)
PMID 16978417, PMID 21516036, PMID 23122829, PMID 23353941, PMID 23984731, PMID 28515092, PMID 29277353, PMID 29299402, PMID 29766091, PMID 30184183, PMID 31227287, PMID 34024658, PMID 34447389, PMID 34580096, PMID 37479616, PMID 39395531, PMID 42425122, PMID 42573415