204 completed, 44 unknown, 26 recruiting, 20 terminated. 127 Not applicable, 57 Phase 3, 28 Phase 2, 27 Phase 4, 8 Phase 1.
Follow Otitis: new trials by email Literature Review of Otitis trials Research Report on Otitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Amoxicillin-clavulanate Versus Amoxicillin Versus Placebo in Acute Otitis Media in Children Amoxicillin, Amoxicillin + Clavulanate, Placebo - Acute Otitis Media, AOM - Acute Otitis Media | Phase 4 | Not yet recruiting | Kuopio University Hospital | 219 | 2026-11-01 | 2026-10-16 |
| Enhanced Telemedicine in Primary Care for Acute Respiratory Tract Infections Study Tele-Otoscope Enabled Primary Care, eBook-supported primary care - Acute Respiratory Tract Infection, Ear Infection | Not applicable | Not yet recruiting | University of Pittsburgh | 450 | 2026-11-01 | 2026-10-27 |
| Does Adding a Fascial Layer to the Cartilage in Tympanoplasty for Large Tympanic Membrane Perforation Affect the Overall Results? Conchal Cartilage and Perichondrium Tympanoplasty, Conchal Cartilage, Perichondrium, and Temporalis Fascia Tympanoplasty - Tympanic Membrane Perforation, Otitis Media | Not applicable | Not yet recruiting | Assiut University | 50 | 2026-10-01 | 2026-09-22 |
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Otitis Media) Amoxicillin, Amoxicillin-Clavulanate, Amoxicillin Placebo - Acute Otitis Media (AOM) | Phase 4 | Recruiting | Nader Shaikh | 1100 | 2026-10-01 | 2026-10-20 |
| Towards Implementation of Universal Newborn Hearing Screening in Kenya Hearing and ear health screening - Hearing Loss, Bilateral or Unilateral, Otitis Media With Effusion in Children | Not applicable | Recruiting | University of Washington | 400 | 2026-09-24 | 2026-10-16 |
| Comparative Study of Adherence to Antibiotic Therapy Among Pediatric Patients: Hospital Emergency Department vs. Primary Care Center Tonsillitis Acute, Pneumonia - Bacterial | Not yet recruiting | University Hospital, Montpellier | 191 | 2026-09-01 | 2026-07-17 | |
| Microbiological Screening Of Malignant Otitis Externa Patients Presenting at Sohag University Hospitals ear swab and susceptibility testing - Malignant Otitis Externa | Recruiting | Sohag University | 40 | 2026-09-01 | 2026-08-27 | |
| Parent-led Assessment and Recognition of AOM Using Digital Ear Imaging Assigning of a digital otoscope to the families in the intervention group - Acute Otitis Media, Otitis Media | Not applicable | Recruiting | Turku University Hospital | 40 | 2026-09-01 | 2026-09-08 |
| EarFlo: A Non-Invasive Treatment for Otitis Media With Effusion & Eustachian Tube Dysfunction in Adults EarFlo Device - Otitis Media With Effusion (OME), Eustachian Tube Dysfunction | Not applicable | Not yet recruiting | Philip Perez | 100 | 2026-08-27 | 2026-08-20 |
| Osteopathic Manipulative Treatment for Children With Chronic or Recurrent Otitis Media Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol - Otitis Media, Otitis Media Effusion | Not applicable | Not yet recruiting | Sarah Vidal | 200 | 2026-08-01 | 2026-06-10 |
| The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health 'Standard of Care PLUS' - Preterm Birth, Preeclampsia | Not applicable | Not yet recruiting | GrowBaby Life Project | 500 | 2026-08-01 | 2026-04-30 |
| CLIKX® Tympanostomy Tube Delivery System for the Placement of Tympanostomy Tubes CLiKX® Tympanostomy Tube Delivery System - Otitis Media, Otitis Media Chronic | Not applicable | Recruiting | ClinQure, Inc. | 80 | 2026-07-07 | 2026-09-11 |
| Post-Market Clinical Follow-Up Study of the Solo+ Tympanostomy Tube Device Solo+ Tympanostomy Tube Device (Solo+ TTD) - Otitis Media, Middle Ear Infections | Recruiting | AventaMed DAC | 160 | 2026-05-21 | 2026-08-13 | |
| SWIR Otoscopy Study SWIR device - Otitis Media, Otitis Media Chronic | Not applicable | Recruiting | Stanford University | 100 | 2026-04-30 | 2026-07-24 |
| Evaluating Laser Otoscope for Middle Ear Effusion Detection Laser otoscope examination - Middle Ear Effusion, Otitis Media | Not yet recruiting | MSTATT LLC | 150 | 2026-03-01 | 2026-03-06 | |
| Digital Otoscopy Versus Standard Otoscopy on the Diagnosis and Treatment of Otitis Media in Young Children Device: Digital Otoscope - Otitis Media, Antimicrobial Stewardship | Not applicable | Active not recruiting | Boston Children's Hospital | 36 | 2026-03-01 | 2026-05-22 |
| Nigella Sativa Oil for Eczematous Otitis Externa Mometasone Furoate (MF), Nigella sativa oil - Eczema/Atopic Dermatitis, Otitis Externa | Not applicable | Recruiting | Bezmialem Vakif University | 85 | 2026-01-12 | 2026-04-21 |
| Validating and AI Software for Assessment of Children With Ear Concerns Otalgia, Otitis Media | Not yet recruiting | Glimpse Diagnostics, Inc. | 658 | 2026-01-01 | 2025-11-21 | |
| Laser Acupuncture for Otitis Media With Effusion in Children Laser Acupuncture, Sham Laser Acupuncture - Otitis Media With Effusion | Not applicable | Completed | Universitas Indonesia | 32 | 2025-12-29 | 2026-06-04 |
| Artificial Intelligence Diagnostic Decision Support to Reduce Antimicrobial Prescriptions in Young Children With Colds Standard Clinical Ear Exam, AI app ear exam and diagnosis - Acute Otitis Media (AOM), Upper Respiratory Infection | Not applicable | Recruiting | Timothy Shope | 300 | 2025-12-04 | 2026-10-08 |
Showing 20 of 328. Sign in to see all of them.
Otitis Media (219) · Otitis Media with Effusion (80) · Respiratory Tract Infections (18) · Pneumonia (15) · Hearing Loss (13) · Pharyngitis (13) · Otitis Externa (12) · Hearing Loss, Conductive (8) · Streptococcal Infections (8) · Tympanic Membrane Perforation (8) · Earache (7) · Influenza, Human (7) · Labyrinthitis (7) · Otitis Media, Suppurative (7)
Otorhinolaryngologic Diseases (325) · Ear Diseases (323) · Infections (72) · Pathological Conditions, Signs and Symptoms (59) · Otitis Media (57) · Respiratory Tract Diseases (51) · Signs and Symptoms (47) · Neurologic Manifestations (37) · Nervous System Diseases (34) · Respiratory Tract Infections (29) · Lung Diseases (25) · Stomatognathic Diseases (25) · Sensation Disorders (22) · Bacterial Infections and Mycoses (20)
Ciprofloxacin (14) · Amoxicillin-Potassium Clavulanate Combination (13) · Middle Ear Ventilation (11) · Amoxicillin (8) · Adenoidectomy (7) · Dexamethasone (6) · Azithromycin (4) · Benzocaine (4) · Data Collection (4) · PHiD-CV vaccine (4) · 13-valent pneumococcal vaccine (3) · Cefdinir (3) · Educational Status (3) · Hepatitis A Vaccines (3) · Hepatitis B Vaccines (3)
University of Pittsburgh (13) · GlaxoSmithKline (12) · Alcon Research (9) · Integra LifeSciences Corporation (9) · Otonomy, Inc. (7) · Pfizer (7) · Boston Children's Hospital (5) · Children's Hospital of Philadelphia (5) · Menzies School of Health Research (5) · AventaMed DAC (4) · National Institute on Deafness and Other Communication Disorders (NIDCD) (4) · University Hospital Ostrava (4) · University of Washington (4) · Abbott (3) · Arbor Pharmaceuticals, Inc. (3)
United States (133) · Israel (19) · Canada (16) · France (13) · Finland (12) · Australia (8) · Belgium (7) · Costa Rica (7) · Turkey (Türkiye) (7) · Italy (6) · Panama (6) · Sweden (6) · Czechia (5) · Germany (5) · Spain (5)
Carl LeBel, PhD (6) · Cuneyt M Alper, MD (6) · William J Doyle, PhD (5) · Amanda J Leach, PhD (4) · Matija Daniel (4) · Alejandro Hoberman, MD (3) · Louis Vernacchio, MD, MSc (3) · Yehudah Roth, MD (3) · Aino Ruohola, MD, PhD (2) · Andrea Shane, MD, MPH, MSc (2) · Edward K Mulholland, DM (2)
PMID 42572144, PMID 26985629, PMID 28006041, PMID 34986178, PMID 35772449, PMID 36211411, PMID 37171965, PMID 37965944, PMID 38088821, PMID 38829821, PMID 40008607, PMID 10886700, PMID 11172176, PMID 12384383, PMID 12470586, PMID 1394754, PMID 14557958, PMID 14742362, PMID 16101707, PMID 1616162, PMID 16324031, PMID 16613928, PMID 16790626, PMID 16968847, PMID 17133154, PMID 17179249, PMID 17229952, PMID 17646493, PMID 18499600, PMID 18831749, PMID 19150378, PMID 19728873, PMID 19776196, PMID 20368317, PMID 20399511, PMID 20538749, PMID 20815736, PMID 21098526, PMID 21106443, PMID 21226576, PMID 21226577, PMID 21576556, PMID 21645573, PMID 21740160, PMID 21846295, PMID 22230559, PMID 22466327, PMID 22669347, PMID 22926176, PMID 23158882
P50DC007667 (7), 2008 (2), 2025 (2), 2014 (1), 2015 (1), 2023 (1), K22CA163747 (1), P50AT000008 (1), R01AI201390 (1), R01DC002620 (1), R01DC005630 (1), R01DC011524 (1), R01DC019412 (1), R01DC021326 (1), R21CA184337 (1)