297 completed, 56 unknown, 38 recruiting, 17 not yet recruiting. 116 Phase 3, 96 Phase 2, 65 Not applicable, 43 Phase 4, 33 Phase 1.
Follow Meningitis: new trials by email Literature Review of Meningitis trials Research Report on Meningitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimizing Care for Cryptococcal Antigenemia: Evaluation of Short Course Fluconazole and ART Timing Among CrAg+ Persons With Low Titers Immediate ART Initiation, Delayed ART Initiation, 10-Week Fluconazole - Cryptococcal Antigenemia, HIV-1-infection | Phase 3 | Not yet recruiting | University of Minnesota | 505 | 2027-01-05 | 2026-09-03 |
| Immune-Mitochondrial Correction in Military Recruits Multivitamin/Mineral supplements, Sodium nucleinate combination - Respiratory Tract Infections (RTI), Meningitis | Not applicable | Not yet recruiting | MIPO Clinic | 200 | 2027-01-01 | 2026-06-29 |
| Aciclovir Versus Placebo for HSV-2 Meningitis Acyclovir 50 MG/ML, Placebo - Herpes Simplex 2, Meningitis, Viral | Phase 4 | Not yet recruiting | Jacob Bodilsen | 150 | 2027-01-01 | 2026-10-28 |
| THiamine for Recovery In Vulnerable Early-life Infections thiamine hydrochloride 100 mg, Placebo - Meningitis, Bacteremia | Phase 2 | Not yet recruiting | Milton S. Hershey Medical Center | 240 | 2026-12-01 | 2026-10-09 |
| A Pivotal Safety and Immunogenicity GBS-NN/NN2 Vaccine Maternal Immunisation Trial GBS-NN/NN2 vaccine, Placebo - Streptococcus Agalactiae Infection, Neonatal Sepsis | Phase 2 / Phase 3 | Not yet recruiting | Minervax ApS | 6600 | 2026-11-30 | 2026-11-06 |
| Pain Phenotyping of Rheumatic Diseases - An Observational Study Bedside quantitative sensory testing - Rheumatic Diseases, Lupus Erythematosus, Systemic | Recruiting | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 225 | 2026-11-16 | 2026-11-05 | |
| Single-center, Open-label Study: Immunogenicity and Safety Observation After Vaccination With ACYW135 Meningococcal Polysaccharide Vaccine in Junior High School Students Aged 13-15 Years MPSV-ACYW - Meningococcal Disease; Meningococcal Meningitis | Phase 4 | Not yet recruiting | Zhejiang Provincial Center for Disease Control and Prevention | 200 | 2026-10-20 | 2026-10-21 |
| Exploring the Combination of Intracalvariosseous and Intravenous Antibiotics for Moderate to Severe Bacterial Meningitis Intracalvariosseous injection vancomycin/tigecycline/polymyxin B, Intravenous injection vancomycin/tigecycline/polymyxin B, Conventional treatment - Blood-Brain Barrier, Bacterial Meningitis | Not applicable | Not yet recruiting | yilong Wang | 9 | 2026-09-21 | 2026-09-17 |
| A Clinical Trial of the ACYW135 Group Meningococcal Polysaccharide-Conjugated Vaccine (CRM197 Vector) Previously vaccinated with MCV4 (CanSino), Previously vaccinated with MPSV4 (LvZhu) - Epidemic Meningitis | Not yet recruiting | CanSino Biologics Inc. | 180 | 2026-09-15 | 2026-08-03 | |
| Group-based Emotional Awareness and Expression Therapy to Support Recovery After Acquired Brain Injury: A Clinical Development and Evaluation Study TAU + Group Therapy (EAET), Treatment as Usual (TAU) - Aquired Brain Injury, Stroke | Not applicable | Recruiting | Uppsala University | 110 | 2026-09-15 | 2026-10-01 |
| Clinical Characteristics and Prognostic Factors in Patients With Meningitis at Sohag Governorate. Meningitis | Not yet recruiting | Sohag University | 300 | 2026-08-15 | 2026-08-17 | |
| BPaLMZ for TB Meningitis BPaLMZ Regimen - Tuberculous Meningitis, HIV | Phase 2 | Recruiting | David Boulware | 312 | 2026-07-28 | 2026-10-16 |
| Metagenomic Analysis of the Pharynx in High Risk Partners Gonorrhea, Neisseria Gonorrhea | Not yet recruiting | Guy's and St Thomas' NHS Foundation Trust | 100 | 2026-07-14 | 2026-06-30 | |
| Safety, Pharmacokinetics and Efficacy of BV100 Plus Low Dose Polymyxin B Plus Ceftazidime/Avibactam, or Plus Cefiderocol in Patients With Pulmonary and Extrapulmonary Infections Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex BV100 with 50 mg polymyxin B plus ceftazidime/avibactam, BV100 with 50 mg polymyxin B plus cefiderocol, Best Available Therapy (BAT) - Ventilator Associated Bacterial Pneumonia (VABP), Hospital Acquired Bacterial Pneumonia (HABP) | Phase 2 | Not yet recruiting | BioVersys AG | 120 | 2026-07-01 | 2026-02-24 |
| Olorofim in Early Coccidioidal Meningitis olorofim - Coccidioidal Meningitis | Phase 2 | Recruiting | Fariba Donovan | 12 | 2026-06-01 | 2026-07-27 |
| Hemorrhage Elimination During Lumbar Puncture Using Ultrasound Measurements (HELPUS) ultrasound contrast - Lumbar Puncture | Not applicable | Recruiting | Vanderbilt University Medical Center | 80 | 2026-05-16 | 2026-05-29 |
| Prediction of Infectious Agents in the Biofire® FilmArray bioMérieux Meningitis/Encephalitis Panel Based on Clinical Syndrome and Cerebrospinal Fluid Parameters: a Diagnostic Stewardship Proposal. Biofire FilmArray Meningitis/Encephalitis Panel - Meningitis, Encephalitic Infection | Not applicable | Recruiting | Federal University of Health Science of Porto Alegre | 182 | 2026-04-13 | 2026-08-21 |
| Intracalvariosseous Plus Intravenous Antibiotics for Moderate-to-Severe Bacterial Meningitis Intracalvariosseous injection vancomycin/tigecycline/polymyxin B, Intravenous injection vancomycin/tigecycline/polymyxin B, Conventional treatment - Blood-Brain Barrier, Bacterial Meningitis | Not applicable | Not yet recruiting | yilong Wang | 86 | 2026-04-01 | 2026-03-27 |
| Phase 2a Trial of Alpibectir Plus Ethionamide for Tuberculosis Meningitis HRZE, HRZE plus Alpe375, HRZE plus AlpE500 - Tuberculosis Meningitis | Phase 2 | Not yet recruiting | BioVersys AG | 64 | 2026-03-30 | 2026-03-03 |
| Acute Treatment and Long-term Assessment of Adult Infectious Meningitis Viral Meningitis, Bacterial Meningitis | Recruiting | Hospital Israelita Albert Einstein | 624 | 2026-03-30 | 2026-11-05 |
Showing 20 of 444. Sign in to see all of them.
Meningitis, Meningococcal (125) · Meningococcal Infections (104) · Meningitis, Cryptococcal (54) · Meningitis, Bacterial (35) · Encephalitis (32) · Acquired Immunodeficiency Syndrome (30) · HIV Infections (30) · Tuberculosis, Meningeal (30) · Pneumonia (22) · Sepsis (22) · Cryptococcosis (21) · AIDS-Related Opportunistic Infections (18) · Tetanus (12) · Whooping Cough (12)
Neuroinflammatory Diseases (444) · Nervous System Diseases (441) · Infections (368) · Bacterial Infections and Mycoses (314) · Central Nervous System Diseases (305) · Central Nervous System Infections (267) · Bacterial Infections (252) · Central Nervous System Bacterial Infections (193) · Gram-Negative Bacterial Infections (183) · Neisseriaceae Infections (170) · Meningitis, Bacterial (158) · Pathological Conditions, Signs and Symptoms (77) · Virus Diseases (75) · Meningococcal Infections (66)
Meningococcal Vaccines (60) · Fluconazole (28) · Amphotericin B (23) · 4CMenB vaccine (16) · Flucytosine (13) · MenACWY-CRM vaccine (11) · Heptavalent Pneumococcal Conjugate Vaccine (9) · Vaccines (8) · Rifampin (7) · Linezolid (6) · MenACWY (6) · Tetanus Toxoid (6) · 13-valent pneumococcal vaccine (5) · Chickenpox Vaccine (5) · HibTITER protein, Haemophilus influenzae (5)
Sanofi Pasteur, a Sanofi Company (48) · Novartis Vaccines (35) · GlaxoSmithKline (22) · Pfizer (22) · National Institute of Allergy and Infectious Diseases (NIAID) (11) · Novartis (9) · CanSino Biologics Inc. (8) · University of Oxford (7) · Assistance Publique - Hôpitaux de Paris (6) · Wyeth is now a wholly owned subsidiary of Pfizer (6) · Oxford University Clinical Research Unit, Vietnam (5) · University of Minnesota (5) · ANRS, Emerging Infectious Diseases (4) · Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd (4) · Sinovac Biotech Co., Ltd (4)
United States (117) · China (41) · United Kingdom (33) · France (29) · Canada (19) · Germany (18) · Uganda (16) · Spain (15) · Italy (14) · Australia (12) · Brazil (12) · Finland (12) · India (12) · Poland (11) · Puerto Rico (11)
Fubao Ma, Bachelor (3) · Robert C Read (3) · Sarah Johnson (3) · Alberto Yataco, MD (2) · Andrew J Pollard, PhD (2) · Arezou Khosroshahi, MD (2) · Armstrong D (2) · Damon Scales, MD, PhD (2)
PMID 35164991, PMID 39972326, PMID 29253560, PMID 29550195, PMID 30325463, PMID 32681472, PMID 32843994, PMID 33283229, PMID 33325757, PMID 36369456, PMID 36462524, PMID 41574175, PMID 11227314, PMID 16203934, PMID 16417952, PMID 16509475, PMID 17072120, PMID 17173226, PMID 17548138, PMID 17909804, PMID 19048025, PMID 19150378, PMID 19441980, PMID 19476428, PMID 19776196, PMID 19812260, PMID 19895922, PMID 19897055, PMID 20164251, PMID 20189491, PMID 20415574, PMID 20431379, PMID 20439595, PMID 20655261, PMID 20813797, PMID 20943209, PMID 21148522, PMID 21177912, PMID 21339701, PMID 21389149, PMID 21645573, PMID 21817954, PMID 21910214, PMID 21987006, PMID 22094635, PMID 22094636, PMID 22174748, PMID 22484295, PMID 22569484, PMID 22622049
2016 (7), 2017 (7), 2009 (3), 2014 (3), 2019 (3), 2008 (2), 2018 (2), 2005 (1), K01DK075478 (1), R01HD074944 (1), R01HD122957 (1), R01NS086312 (1), R21TW011035 (1), R21TW012439 (1), U01AI089244 (1)