30 completed, 17 unknown, 7 not yet recruiting, 6 recruiting. 46 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 46 | Completed 22, Unknown 10, Not yet recruiting 6, Recruiting 4, Active not recruiting 2, Terminated 2 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
Follow this drug Literature Review of Open Fracture Reduction trials Research Report on Open Fracture Reduction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Management of Diaphyseal Forearm Fractures in Adolescents Open reduction and internal fixation, Closed or mini-open reduction and fixation - Forearm Fractures | Not applicable | Not yet recruiting | Sohag University | 20 | 2026-07-15 | 2026-07-15 |
| Effect of Adipose Tissue Derived Autologous Mesenchymal Stem Cell Concentrate on Bone Quality in Mandibular Fracture Healing. Adipose tissue derived mesenchymal stem cells concentrate application in addition to the open reduction and internal fixation., Open reduction and internal fixation - Mandible Fracture | Not applicable | Not yet recruiting | Cairo University | 20 | 2026-07-01 | 2026-06-29 |
| Multicenter Clinical Study on Robotic-Assisted Surgical Management of Posterior Cruciate Ligament Tibial Avulsion Fractures Surgical robot-assisted arthroscopic surgery, Open reduction and internal fixation surgery - PCL - Posterior Cruciate Ligament Deficiency, Posterior Cruciate Ligament Tear | Not applicable | Not yet recruiting | Beijing Tsinghua Chang Gung Hospital | 22 | 2026-05-10 | 2026-05-08 |
| Comparative Study Between Internal Fixtion And Primary Subtalar Arthrodesis In Comminuted Intra-Articular Calcaneal Fracture Primary Subtalar Arthrodesis, Open reduction and internal fixation - Calcaneus Fractures | Not applicable | Not yet recruiting | Ahmed Gamal Ibrahim Saleh | 40 | 2026-03-01 | 2026-02-20 |
| This is a Study to Find Out Whether Surgery Using a Metal Plate to Fix a Broken Elbow in Older Adults Leads to Better Recovery and Arm Function Compared to Non-surgical Treatment Open reduction and plate osteosynthesis, Conservative treatment with early mobilisation - Olecranon Fracture | Not applicable | Recruiting | Ente Ospedaliero Cantonale, Bellinzona | 84 | 2026-02-03 | 2026-09-09 |
| Home-Based Photobiomodulation Effects in the Postoperative Period of Distal Radius Fractures Open reduction and internal fixation (ORIF) with locked volar plate, Home exercises, Active photobiomodulation - Distal Radius Fracture | Not applicable | Recruiting | University of Nove de Julho | 42 | 2025-09-06 | 2026-09-29 |
| Traditional Mongolian Medicine Bone-Setting Versus Surgery for Humeral Surgical Neck Fracture Traditional Mongolian Medicine Bone-Setting, Open Reduction and Internal Fixation - Proximal Humerus Fracture | Not applicable | Completed | Mongolian National University of Medical Sciences | 60 | 2025-06-30 | 2026-08-18 |
| Posterior Column Fractures of Tibial Plateau Open reduction and internal fixation - Tibial Plateau Fractures | Not yet recruiting | Assiut University | 32 | 2025-05-01 | 2025-04-17 | |
| 3D Titanium Plates for Mandibular Parasymphyseal Fracture Fixation 3D Titanium Plates - Mandibular Parasymphyseal Fractures | Not applicable | Completed | Cairo University | 18 | 2024-12-15 | 2026-06-16 |
| 3D Titanium Plates for Mandibular Body Fracture Fixation 3D Titanium Plates - Mandibular Body Fracture | Not applicable | Completed | Cairo University | 18 | 2024-12-15 | 2026-06-16 |
| Weight-bearing of Surgically Treated Acetabular Fractures. Open reduction and internal fixation (ORIF) - Acetabular Fracture | Not applicable | Not yet recruiting | Hospital District of Helsinki and Uusimaa | 50 | 2024-05-01 | 2024-03-06 |
| Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study Open Reduction & Internal Fixation - Mandibular Fractures | Unknown | Aya Ayman Ahmed | 2 | 2024-04-15 | 2024-04-05 | |
| Evaluation of Z-shaped Bone Plates in Management of Mandibular Fractures open reduction and internal fixation with bone plate, z-plates., conventional miniplates. - Mandibular Fracture Treatment | Not applicable | Active not recruiting | Suez Canal University | 18 | 2024-01-28 | 2025-09-22 |
| V Shaped Plate Vs Champy Technique in Mandibular Angle Fractures Open reduction and internal fixation of mandibular angle fracture using V shaped plate - Fractures, Bone | Not applicable | Unknown | Cairo University | 40 | 2023-08-01 | 2023-08-22 |
| Outcome of Surgical Fixation of Multiple Fractured Ribs at Sohag University Hospital surgical rib fixation - Multiple Fractures of Ribs | Not applicable | Unknown | Sohag University | 60 | 2023-08-01 | 2023-08-04 |
| OCT in Open Fracture and Infected Fracture Open Fracture, Infected Fracture - Trauma Injury, Trauma | Recruiting | Dartmouth-Hitchcock Medical Center | 40 | 2023-03-27 | 2026-10-02 | |
| Cast or Operation for Medial Epicondyle Fracture Treatment in Children open reduction and internal fixation (ORIF), cast immobilization - Fracture Elbow | Not applicable | Recruiting | Joseph Janicki | 334 | 2022-10-28 | 2026-07-01 |
| Efficacy of the Use of 3D Printing Models in the Treatment of Tibial Plateau Fractures: a Randomized Clinical Trial Open reduction and internal fixation, Standard osteosynthesis planning, 3-D model osteosynthesis planning - Tibial Plateau Fracture | Not applicable | Completed | Pedro-José Torrijos-Garrido | 35 | 2022-10-01 | 2026-09-25 |
| A Comparative Study Between Positional and Lag Screws for the Fixation of Medial Malleolar Fractures Open reduction and internal fixation - Medial Malleolus Fracture, Ankle Fractures | Not applicable | Unknown | Kasr El Aini Hospital | 34 | 2022-08-18 | 2022-10-10 |
| The Role of Intraoperative Navigation-assisted Channel Screw Technique in the Treatment of Pelvic Fractures Intraoperative navigation combined with Catheter screw technique, Open reduction and internal fixation with steel plate - Pelvic Fracture | Not applicable | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 100 | 2022-07-01 | 2022-08-01 |
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Wrist Fractures (12) · Fractures, Bone (8) · Mandibular Fractures (6) · Ankle Fractures (4) · Colles' Fracture (3) · Hip Fractures (3) · Radius Fractures (3) · Wounds and Injuries (3) · Humeral Fractures (2) · Tibial Fractures (2) · Tibial Plateau Fractures (2) · Accidental Injuries (1) · Developmental Dysplasia of the Hip (1) · Elbow Fractures (1) · Femoral Fractures, Distal (1)
Cairo University (4) · Sohag University (4) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (2) · Kasr El Aini Hospital (2) · McGill University Health Centre/Research Institute of the McGill University Health Centre (2) · AO Clinical Investigation and Publishing Documentation (1) · Ahmed Gamal Ibrahim Saleh (1) · Ain Shams University (1) · Assiut University (1) · Aya Ayman Ahmed (1) · B.P. Koirala Institute of Health Sciences (1) · Beijing Tsinghua Chang Gung Hospital (1) · Charite University, Berlin, Germany (1) · Children's Hospital of Chongqing Medical University (1)
Egypt (12) · Canada (6) · China (5) · United States (5) · Finland (4) · Spain (4) · Germany (3) · Netherlands (3) · United Kingdom (3) · Brazil (2) · Norway (2) · Romania (2) · Sweden (2) · Switzerland (2) · Bangladesh (1)
Claudia Lamas, Ph D (2) · J. Carel Goslings, MD, PhD (2) · Mohamed Atef, Professor (2) · Ali F Abdelrahem, lecturer (1) · Aly M Mohamed, Prof (1) · Amir Khoshbin, MD (1) · Amr A. Gomaa, associate professor (1) · Antti Paakkala, MD;PhD (1) · Carlo Biz, MD (1) · Carlos M Olarte, MD (1) · Caroline E Plant, BSc, MBChB (1) · Chen Shunyou, Phd (1) · Davide Previtali, MD (1) · Eman M. Eldemardash, assistant lecturer (1)
PMID 10853896, PMID 11600115, PMID 11988725, PMID 15168178, PMID 15187469, PMID 1556609, PMID 15714304, PMID 16752291, PMID 17079389, PMID 17088659, PMID 17088660, PMID 17452711, PMID 19523625, PMID 21678350, PMID 21915231, PMID 22144745, PMID 22258990, PMID 22588106, PMID 22659630, PMID 22947239, PMID 23471713, PMID 23994004, PMID 26860090, PMID 27513920, PMID 29394904, PMID 29952895, PMID 30126393, PMID 30657531, PMID 31951273, PMID 32433648, PMID 32589939, PMID 33337492, PMID 3356728, PMID 34137830, PMID 34142664, PMID 35549696, PMID 36780156, PMID 37133402, PMID 38482816, PMID 3980544, PMID 40405317, PMID 4066292, PMID 40711571, PMID 42129866, PMID 7054192, PMID 7462281, PMID 7838503, PMID 8326423, PMID 8355300, PMID 8423295
2017 (1), R01AR062066 (1), U01AR079113 (1)