57 completed, 30 unknown, 14 recruiting, 8 not yet recruiting. 81 Not applicable, 2 Phase 1, 2 Phase 2, 2 Phase 4, 1 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Virtual Surgical Planning and Preoperative Plate Bending for Maxillofacial Fractures Conventional Open Reduction and Internal Fixation With Intraoperative Plate Bending, Virtual Surgical Planning-Assisted Open Reduction and Internal Fixation With Preoperative Plate Bending - Mandibular Fractures, Maxillofacial Injuries | Not applicable | Not yet recruiting | University of Medicine and Pharmacy at Ho Chi Minh City | 30 | 2026-09-20 | 2026-10-02 |
| Management of Diaphyseal Forearm Fractures in Adolescents Open reduction and internal fixation, Closed or mini-open reduction and fixation - Forearm Fractures | Not applicable | Not yet recruiting | Sohag University | 20 | 2026-07-15 | 2026-07-15 |
| Robot-Assisted Closed Reduction and Internal Fixation for Intertrochanteric Femoral Fractures Robot-assisted closed reduction and internal fixation, Conventional manual closed reduction and internal fixation - Intertrochanteric Fractures, Intertrochanteric Fractures of the Hip | Not applicable | Recruiting | Beijing Jishuitan Hospital | 60 | 2026-07-01 | 2026-07-31 |
| Effect of Adipose Tissue Derived Autologous Mesenchymal Stem Cell Concentrate on Bone Quality in Mandibular Fracture Healing. Adipose tissue derived mesenchymal stem cells concentrate application in addition to the open reduction and internal fixation., Open reduction and internal fixation - Mandible Fracture | Not applicable | Not yet recruiting | Cairo University | 20 | 2026-07-01 | 2026-06-29 |
| Robot-Assisted Closed Reduction and Internal Fixation for Distal Femoral Fractures Robot-assisted closed reduction, Conventional fracture reduction and internal fixation - Supracondylar Femoral Fractures, Femoral Fractures | Not applicable | Recruiting | Beijing Jishuitan Hospital | 80 | 2026-07-01 | 2026-07-31 |
| Comparative Study Between Internal Fixtion And Primary Subtalar Arthrodesis In Comminuted Intra-Articular Calcaneal Fracture Primary Subtalar Arthrodesis, Open reduction and internal fixation - Calcaneus Fractures | Not applicable | Not yet recruiting | Ahmed Gamal Ibrahim Saleh | 40 | 2026-03-01 | 2026-02-20 |
| MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP) Hip arthroplasty, Internal fixation - Femoral Neck Fractures | Not applicable | Recruiting | University of Southern California | 600 | 2026-01-23 | 2026-10-05 |
| Accuracy of Virtual Surgical Planning Versus Traditional Technique in Zygomaticomaxillary Fracture Reduction Virtual surgical planning and 3D model printing, Prebent titanium miniplates, Conventional open reduction and internal fixation (ORIF) - Facial Bone Fracture, Maxillofacial Injury | Not applicable | Not yet recruiting | Suez Canal University | 20 | 2025-12-25 | 2025-12-12 |
| Home-Based Photobiomodulation Effects in the Postoperative Period of Distal Radius Fractures Open reduction and internal fixation (ORIF) with locked volar plate, Home exercises, Active photobiomodulation - Distal Radius Fracture | Not applicable | Recruiting | University of Nove de Julho | 42 | 2025-09-06 | 2026-09-29 |
| Traditional Mongolian Medicine Bone-Setting Versus Surgery for Humeral Surgical Neck Fracture Traditional Mongolian Medicine Bone-Setting, Open Reduction and Internal Fixation - Proximal Humerus Fracture | Not applicable | Completed | Mongolian National University of Medical Sciences | 60 | 2025-06-30 | 2026-08-18 |
| Plate Fixation Versus Percutaneous Cannulated Screw Insertion in Sanders Type II and Type III Calcaneal Fractures percutaneous cannulated screw fixation, Plate fixation - Calcaneus Fractures | Not applicable | Active not recruiting | Ain Shams University | 48 | 2025-05-15 | 2025-08-08 |
| Posterior Column Fractures of Tibial Plateau Open reduction and internal fixation - Tibial Plateau Fractures | Not yet recruiting | Assiut University | 32 | 2025-05-01 | 2025-04-17 | |
| Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Trial Internal Fixation, Resection and reconstruction - Metastatic Bone Disease | Not applicable | Recruiting | Michelle Ghert, MD | 334 | 2025-02-01 | 2026-07-08 |
| Early Versus Late Intervention in Maxillofacial Trauma Timing of Open Reduction and Internal Fixation (ORIF) - Maxillofacial Trauma | Completed | Haifa Mohammed Sharaf-Aldeen | 50 | 2025-02-01 | 2026-08-06 | |
| Prospective Evaluation of Anterior Aesthetic Rib Cage Remodeling With Osteosynthesis for Lower Anterior Thoracic Prominence Anterior Aesthetic Rib Cage Remodeling With Osteosynthesis, Chest CT and Spirometry Follow-up - Chest Wall Deformity, Prominent Lower Rib Cage | Recruiting | Research Inc | 160 | 2025-01-01 | 2026-09-10 | |
| Influence of Cemented Cephalic Augmentation on the Outcome of Intramedullary Nailing in Pertrochanteric Hip Fractures intramedullary nailing augmentation, intramedullary nailing - Hip Fracture of Intertrochanteric Type | Not applicable | Recruiting | Diego Matías Domínguez Prado | 314 | 2024-09-30 | 2026-09-02 |
| Weight-bearing of Surgically Treated Acetabular Fractures. Open reduction and internal fixation (ORIF) - Acetabular Fracture | Not applicable | Not yet recruiting | Hospital District of Helsinki and Uusimaa | 50 | 2024-05-01 | 2024-03-06 |
| Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study Open Reduction & Internal Fixation - Mandibular Fractures | Unknown | Aya Ayman Ahmed | 2 | 2024-04-15 | 2024-04-05 | |
| Evaluation of Z-shaped Bone Plates in Management of Mandibular Fractures open reduction and internal fixation with bone plate, z-plates., conventional miniplates. - Mandibular Fracture Treatment | Not applicable | Active not recruiting | Suez Canal University | 18 | 2024-01-28 | 2025-09-22 |
| FARE Augmentation of Proximal Femoral Fractures With CaS/HA and Systemic ZA OSTEOSYNTHESIS, Zoledronic acid, CERAMENT BONE VOID FILLER (BVF) - Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur | Phase 4 | Completed | Aksaray University | 20 | 2023-12-01 | 2026-01-21 |
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Wrist Fractures (15) · Hip Fractures (13) · Femoral Neck Fractures (12) · Fractures, Bone (10) · Mandibular Fractures (8) · Ankle Fractures (6) · Radius Fractures (5) · Tibial Fractures (4) · Colles' Fracture (3) · Femoral Fractures (3) · Maxillofacial Injuries (3) · Pain (3) · Shoulder Fractures (3) · Elbow Fractures (2) · Foot Diseases (2)
Ain Shams University (3) · Danderyd Hospital (3) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (3) · Kasr El Aini Hospital (3) · Beijing Jishuitan Hospital (2) · Instituto Traumatologico Dr. Teodoro Gebauer Weisser (2) · McGill University Health Centre/Research Institute of the McGill University Health Centre (2) · Ostfold Hospital Trust (2) · Sohag University (2) · Suez Canal University (2) · Ullevaal University Hospital (2) · University Hospital, Akershus (2) · Zimmer Biomet (2) · AO Clinical Investigation and Publishing Documentation (1) · Abdallah Gaber Ali Mohamed (1)
Canada (11) · Egypt (11) · Spain (10) · United States (9) · Norway (7) · France (6) · China (5) · Finland (5) · Germany (5) · United Kingdom (5) · Denmark (4) · Sweden (4) · Belgium (3) · Brazil (3) · Colombia (3)
Claudia Lamas, Ph D (2) · Ali F Abdelrahem, lecturer (1) · Aly M Mohamed, Prof (1) · Amir Khoshbin, MD (1) · Amr A. Gomaa, associate professor (1) · Antti Malmivaara, MD, PhD (1) · Antti Paakkala, MD;PhD (1) · Awab A. Moussa, MD Candidate (1) · Bart Berghs, MD (1) · Bjarke Viberg, MD, PhD (1) · Carlo Biz, MD (1) · Carlos M Olarte, MD (1) · Caroline E Plant, BSc, MBChB (1)
PMID 35727196, PMID 35309986, PMID 1421796, PMID 14648267, PMID 15006336, PMID 15213501, PMID 15686241, PMID 1587874, PMID 1588193, PMID 16501984, PMID 17331628, PMID 18056740, PMID 18376008, PMID 21997224, PMID 23104043, PMID 23204970, PMID 25538072, PMID 25637730, PMID 27513920, PMID 29394904, PMID 29411672, PMID 29952895, PMID 30126393, PMID 30657531, PMID 30885393, PMID 31951273, PMID 31964340, PMID 32433648, PMID 32439600, PMID 32589939, PMID 32670600, PMID 33040011, PMID 33337492, PMID 33579338, PMID 34137830, PMID 34142664, PMID 34429951, PMID 34842088, PMID 35549696, PMID 35672754, PMID 35809796, PMID 36217233, PMID 36780156, PMID 37060040, PMID 37133402, PMID 37227483, PMID 37429947, PMID 3818751, PMID 38482816, PMID 39349348
2017 (1), 2019 (1), R01AR062066 (1), U01AR079113 (1)