33 completed, 10 recruiting, 7 unknown, 5 terminated. 63 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 63 | Completed 33, Recruiting 10, Unknown 7, Terminated 5, Withdrawn 5, Not yet recruiting 3 |
Follow Suppuration: new trials by email Literature Review of Suppuration trials Research Report on Suppuration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VATS or Intrapleural Enzymatic Therapy for Patients With Empyema. VATS group, IET - Empyema, Pleural, Pleural Infections | Phase 4 | Recruiting | Amsterdam UMC | 164 | 2026-11-07 | 2026-11-10 |
| A Single Dose of Intravenous Penicillin as an Adjunct to Oral Penicillin in the Treatment of Acute Tonsillitis, Peritonsillar Phlegmon, and Peritonsillar Abscess Benzylpenicillin, Isotonic NaCl (Placebo) - Acute Tonsillitis, Peritonsillar Abscess | Phase 4 | Recruiting | Tejs Ehlers Klug | 154 | 2026-11-01 | 2026-11-04 |
| Clinical Efficacy of Stopping Oral Antibiotics When Symptoms Stop, Compared to 'Finishing the Course' Antibiotics for duration of symptoms, Antibiotics for duration of prescribed course - Urinary Tract Infection, Cellulitis | Phase 4 | Recruiting | Murdoch Childrens Research Institute | 200 | 2026-08-18 | 2026-08-21 |
| Study of Efficacy and Safety of Secukinumab in Chinese Adult Patients With Moderate to Severe Hidradenitis Suppurativa Secukinumab - Hidradenitis Suppurativa (HS) | Phase 4 | Recruiting | Novartis Pharmaceuticals | 36 | 2026-06-01 | 2026-09-09 |
| Flush, Lyse, Operate Intrapleural Saline with possible escalation to intraplerual alteplase and dornase. - Complicated Parapneumonic Effusion, Empyema, Pleural | Phase 4 | Not yet recruiting | Dartmouth-Hitchcock Medical Center | 30 | 2026-04-01 | 2026-05-18 |
| A Single-center, Prospective, Self-controlled, Observational Real-world Study of the Efficacy and Safety of Anti-IL-17A/F Monoclonal Antibody Combined With Non-ablative Dot Laser for the Treatment of Mild to Moderate Hidradenitis Suppurativa IL-17A/F mAb + NAFL - Hidradenitis Suppurativa (HS) | Phase 4 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 50 | 2026-04-01 | 2026-04-28 |
| Comparison of the Clinical Efficacy and Safety of Topical and Subcutaneous Injection of Secukinumab in HS Topical injection of Secukinmab, Subcutaneous injection of Secukinumab - Hidradenitis Suppurativa (HS), Hidradenitis Suppurativa (Acne Inversa) | Phase 4 | Not yet recruiting | Peking Union Medical College | 30 | 2025-12-01 | 2025-12-03 |
| Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema Fibrinolytic once daily, Fibrinolytic twice daily, DNA degradation once daily - Pleural Infection Bacterial, Pleural Infections | Phase 4 | Recruiting | University of North Carolina, Chapel Hill | 270 | 2025-09-11 | 2026-09-29 |
| Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections Trimethoprim Sulfamethoxazole - Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute | Phase 4 | Recruiting | Indiana University | 100 | 2025-05-20 | 2026-07-29 |
| APPI-Cost Trial for Perforated Appendicitis PVI, Usual Care - Perforated Appendicitis | Phase 4 | Recruiting | The University of Texas Health Science Center, Houston | 346 | 2025-04-07 | 2025-12-11 |
| Botulinum Toxin-A for Hidradenitis Suppurativa Normal saline, Botulinum toxin type A - Hidradenitis Suppurativa, Hidradenitis Suppurativa \(HS\) | Phase 4 | Withdrawn | Yale University | 2025-01-01 | 2025-12-16 | |
| Comparative Efficacy of Apremilast and Acitretin in Moderate-to-Severe Hidradenitis Suppurativa Apremilast, Acitretin - Hidradenitis Suppurativa | Phase 4 | Completed | Hayat Abad Medical Complex, Peshawar | 70 | 2024-12-22 | 2026-07-16 |
| Adjunctive Clindamycin for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled Trial Clindamycin, Standard of care - Skin Infection, Staphylococcal Infections | Phase 4 | Recruiting | Frieder Schaumburg | 100 | 2024-03-15 | 2024-12-09 |
| High-dose Cephalexin for Cellulitis (HI-DOCC) Cephalexin - Cellulitis | Phase 4 | Completed | Ottawa Hospital Research Institute | 454 | 2023-08-30 | 2026-08-03 |
| Bioequivalence Study of Azithromycin Capsule and Reference Formulation Sumamed * in Healthy Adult Subjects in China test product (T) azithromycin capsule and reference product (R) azithromycin capsule "Sumamed®" - Upper Respiratory Tract Infection, Lower Respiratory Infection | Phase 4 | Completed | Peking University People's Hospital | 48 | 2022-11-16 | 2023-11-28 |
| A Randomized, Controlled Trial Comparing the Use of a Biodegradable Temporizing Matrix to Cadaver Skin in the Reconstruction of Hidradenitis Suppurativa Excisions NovoSorb® BTM, Human Cadaveric Allograft - Hidradenitis Suppurativa | Phase 4 | Unknown | Joseph M. Still Research Foundation, Inc. | 10 | 2022-10-01 | 2023-09-28 |
| Ketamine as a Supplement to Local Anesthesia for Minor Procedures Ketamine, Saline - Pain, Procedural, Minor Laceration | Phase 4 | Recruiting | Loyola University | 108 | 2022-05-25 | 2025-10-03 |
| Optimizing Intralesional Triamcinolone Dosing for Hidradenitis Suppurativa Intralesional Triamcinolone 10 mg/mL, Intralesional Triamcinolone 20 mg/mL, Intralesional Triamcinolone 40 mg/mL - Hidradenitis Suppurativa | Phase 4 | Terminated | Montefiore Medical Center | 11 | 2022-01-24 | 2023-11-13 |
| Local Anesthesia Versus Combined Local Anesthesia With Single Dose Analgesia on Pain Control During Thoracic Ultrasound Guided Procedures Diclofenac, Placebo - Pleural Neoplasms, Aspiration, Respiratory | Phase 4 | Unknown | Assiut University | 100 | 2021-11-01 | 2021-11-16 |
| High-dose vs. Standard-dose Cephalexin for Cellulitis Cephalexin, Cephalexin + placebo - Cellulitis | Phase 4 | Completed | Ottawa Hospital Research Institute | 69 | 2021-08-16 | 2025-01-17 |
Showing 20 of 63. Sign in to see all of them.
Cellulitis (22) · Abscess (14) · Hidradenitis Suppurativa (11) · Empyema, Pleural (7) · Empyema (4) · Infections (4) · Pleural Effusion (4) · Staphylococcal Infections (4) · Abdominal Abscess (3) · Periapical Abscess (3) · Pleural Diseases (3) · Appendicitis (2) · Arthritis, Infectious (2) · Emergencies (2) · Folliculitis (2)
Infections (59) · Pathological Conditions, Signs and Symptoms (44) · Pathologic Processes (43) · Inflammation (41) · Skin and Connective Tissue Diseases (37) · Skin Diseases, Infectious (34) · Bacterial Infections and Mycoses (23) · Connective Tissue Diseases (23) · Bacterial Infections (21) · Skin Diseases (19) · Skin Diseases, Bacterial (17) · Respiratory Tract Diseases (13) · Hidradenitis (11) · Sweat Gland Diseases (11)
Clindamycin (5) · Daptomycin (5) · Ceftriaxone (4) · Cephalexin (4) · Adalimumab (3) · Floxacillin (3) · Saline Solution (3) · Tigecycline (3) · Vancomycin (3) · Cefazolin (2) · Ciprofloxacin (2) · Penicillin V (2) · Sodium Chloride (2) · Tissue Plasminogen Activator (2) · Trimethoprim, Sulfamethoxazole Drug Combination (2)
Wyeth is now a wholly owned subsidiary of Pfizer (3) · GlaxoSmithKline (2) · Ottawa Hospital Research Institute (2) · Aaron Chen (1) · AbbVie (1) · Abbott (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Albert Einstein Healthcare Network (1) · Amsterdam UMC (1) · Assiut University (1) · Christiana Care Health Services (1) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · Dartmouth-Hitchcock Medical Center (1) · Erasmus Medical Center (1) · Frieder Schaumburg (1)
United States (25) · Canada (5) · China (5) · Netherlands (5) · Taiwan (5) · Denmark (4) · United Kingdom (4) · France (3) · Germany (3) · Ireland (3) · Italy (3) · Philippines (3) · South Africa (3) · Spain (3) · Australia (2)
Aaron E Chen, MD (1) · Abel Wakai, MD FRCEM (1) · Adaira Landry, B.A. (1) · Adrian Moughty (1) · Ahmed F Koraitim, MD (1) · Brian Levine, MD (1) · Bruce Friedman, MD (1) · Chris Luke (1) · Conor Deasy (1)
PMID 11555797, PMID 12487041, PMID 17355677, PMID 18090011, PMID 18826731, PMID 19124814, PMID 19222623, PMID 19388915, PMID 19788787, PMID 21063553, PMID 21197290, PMID 22439781, PMID 22653459, PMID 2292525, PMID 23145952, PMID 23247938, PMID 23365053, PMID 24127709, PMID 24799810, PMID 24807602, PMID 24842503, PMID 24885384, PMID 24973422, PMID 24987995, PMID 25605319, PMID 25640693, PMID 25992781, PMID 26300919, PMID 26423784, PMID 27518661, PMID 27531595, PMID 2803357, PMID 28314743, PMID 28836993, PMID 29299899, PMID 29869364, PMID 30321312, PMID 31378847, PMID 31604104, PMID 31641767, PMID 32460374, PMID 34039435, PMID 34406349, PMID 34510518, PMID 34772441, PMID 36592299, PMID 36746171, PMID 37043201, PMID 37328522, PMID 38770982
2015 (1), K12TR004908 (1)