196 completed, 59 recruiting, 37 unknown, 25 terminated. 114 Phase 2, 85 Not applicable, 43 Phase 3, 35 Phase 1, 17 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Early Secukinumab Treatment in Moderate to Severe Hidradenitis Suppurativa Patients Hidradenitis Suppurativa | Not yet recruiting | Novartis Pharmaceuticals | 186 | 2026-11-13 | 2026-10-20 | |
| Efficacy and Safety of Olatorepatide Versus Placebo in Adults With Moderate to Severe Hidradenitis Suppurativa Living With Overweight or Obesity Olatorepatide, Placebo - Hidradenitis Suppurativa | Phase 2 | Not yet recruiting | Regeneron Pharmaceuticals | 300 | 2026-10-30 | 2026-09-21 |
| A Real-world Study of Patients With Hidradenitis Suppurativa and High Cardiovascular Risk or Established Coronary Plaque Treated With Secukinumab Hidradenitis Suppurativa | Not yet recruiting | Novartis Pharmaceuticals | 34 | 2026-10-30 | 2026-09-21 | |
| A Study to Explore the Tissue Level Effects of Remibrutinib in Adults With Moderate to Severe HS LOU064, Placebo - Hidradenitis Suppurativa | Phase 1 | Recruiting | Novartis Pharmaceuticals | 30 | 2026-10-15 | 2026-10-16 |
| A Study to Investigate Efficacy and Safety of Duvakitug in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Duvakitug, Placebo - Hidradenitis | Phase 2 | Not yet recruiting | Sanofi | 156 | 2026-10-13 | 2026-10-14 |
| Skin-in-Sight: a Longitudinal Cohort Infrastructure for Standardized Remote Monitoring and the Evaluation of Digital Care Innovations in Chronic Skin Diseases Psoriasis, Eczema/Atopic Dermatitis | Not yet recruiting | Medisch Spectrum Twente | 1000 | 2026-10-01 | 2026-09-04 | |
| Botulinum Toxin Blockade of Neuronal Signals to Immune Cells as a Novel Treatment for Hidradenitis Suppurativa Botulinum Toxin A (Allergan, Inc, Irvine CA), Placebo - Hidradenitis Suppurativa (HS) | Phase 2 | Not yet recruiting | University of Massachusetts, Worcester | 40 | 2026-10-01 | 2026-09-10 |
| Safety and Efficacy of Soquelitinib in Adults With Hidradenitis Suppurativa Soquelitinib - Hidradenitis Suppurativa (HS) | Phase 1 | Recruiting | Corvus Pharmaceuticals, Inc. | 25 | 2026-09-17 | 2026-10-15 |
| Safety and Efficacy of Roflumilast Foam 0.3% in Adolescent and Adult Subjects With Hidradenitis Suppurativa Roflumilast 0.3% topical foam - Hidradenitis Suppurativa (HS) | Phase 2 | Recruiting | Harrison Dermatology | 10 | 2026-09-10 | 2026-10-13 |
| A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial) SPY072, Placebo, bimekizumab - Hidradenitis Suppurativa (HS) | Phase 2 | Recruiting | Spyre Therapeutics, Inc. | 150 | 2026-09-01 | 2026-10-19 |
| The Safety and Efficacy of Roflumilast Foam in HS Roflumilast 0.3% topical foam - Hidradenitis Suppurativa (HS) | Phase 2 | Recruiting | Beth Israel Deaconess Medical Center | 20 | 2026-09-01 | 2026-07-09 |
| Mediterranean Dietary Intervention for HS Mediterranean Diet Counseling, Mediterranean Food Support - Hidradenitis Suppurativa | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 30 | 2026-09-01 | 2026-09-02 |
| 20% Alcohol With Steroid Local Anesthetic Technique Versus Steroid Local Anesthetic Technique Only in Stellate Ganglion Injection in Idiopathic Palmar Hyperhydrosis Group A, Group B - Hyperhidrosis | Not applicable | Not yet recruiting | Fayoum University Hospital | 50 | 2026-09-01 | 2026-08-26 |
| An Observational Study of Patients With Dermatologic Disease Vitiligo, Atopic Dermatitis | Not yet recruiting | Target PharmaSolutions, Inc. | 2000000 | 2026-09-01 | 2026-09-10 | |
| Urinary Bladder Matrix (UBM) Registry Urinary Bladder Matrix (UBM) Products - Tissue Repair, Soft Tissue Reconstruction | Not yet recruiting | Integra LifeSciences Corporation | 300 | 2026-08-31 | 2026-09-04 | |
| ORKA-002 Versus Placebo in Participants With Moderate-to-Severe Hidradenitis Suppurativa ORKA-002, Placebo - Hidradenitis Suppurativa (HS) | Phase 2 | Recruiting | Oruka Therapeutics, Inc. | 200 | 2026-08-21 | 2026-10-29 |
| A Method Characterization Study to Evaluate Thermoregulatory Sweat Production in Healthy Volunteers and Patients With ROSAH Syndrome) Standardized Controlled Heat Exposure With Gravimetric Sweat Collection - ROSAH Syndrome, Anhidrosis | Not applicable | Not yet recruiting | The Third Xiangya Hospital of Central South University | 30 | 2026-08-15 | 2026-09-10 |
| Pilot MBSR for People With HS Mindfulness-Based Stress Reduction - Hidradenitis Suppurativa (HS) | Not applicable | Active not recruiting | University of California, San Francisco | 17 | 2026-08-10 | 2026-10-29 |
| An Extension Study to Assess Safety and Efficacy of Remibrutinib in Participants With Moderate to Severe HS Remibrutinib - Hidradenitis Suppurativa | Phase 3 | Recruiting | Novartis Pharmaceuticals | 710 | 2026-07-10 | 2026-10-13 |
| Nd:YAG vs Alexandrite Laser Treatment in Hidradenitis Suppurativa Nd:YAG Laser, Alexandrite Laser - Hidradenitis Suppurativa (HS) | Not applicable | Not yet recruiting | Geisinger Clinic | 21 | 2026-07-01 | 2026-04-28 |
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Hidradenitis Suppurativa (281) · Hyperhidrosis (83) · Hidradenitis (33) · Skin Diseases (25) · Psoriasis (23) · Dermatitis, Atopic (21) · Alopecia Areata (11) · Acne Vulgaris (9) · Arthritis, Rheumatoid (9) · Vitiligo (9) · Abscess (8) · Arthritis, Psoriatic (8) · Colitis, Ulcerative (8) · Crohn Disease (8)
Skin and Connective Tissue Diseases (379) · Skin Diseases (355) · Bacterial Infections and Mycoses (282) · Bacterial Infections (281) · Infections (281) · Skin Diseases, Infectious (281) · Suppuration (276) · Skin Diseases, Bacterial (275) · Hidradenitis (254) · Pathological Conditions, Signs and Symptoms (42) · Immune System Diseases (34) · Pathologic Processes (32) · Skin Diseases, Papulosquamous (29) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (28)
Adalimumab (16) · Botulinum Toxins, Type A (16) · secukinumab (14) · oxybutynin (9) · bimekizumab (7) · Glycopyrrolate (5) · Sodium Chloride (5) · remibrutinib (5) · sonelokimab (5) · Lasers (4) · brodalumab (4) · upadacitinib (4) · Aluminum Chloride (3) · Blood Specimen Collection (3) · Injections (3)
Novartis Pharmaceuticals (21) · AbbVie (15) · Incyte Corporation (12) · Henry Ford Health System (7) · Sanofi (7) · UCB Biopharma SRL (6) · University of Miami (6) · Allergan (5) · Botanix Pharmaceuticals (5) · Journey Medical Corporation (5) · Montefiore Medical Center (5) · MoonLake Immunotherapeutics AG (5) · Boehringer Ingelheim (4) · Dr. August Wolff GmbH & Co. KG Arzneimittel (4) · Florida Academic Dermatology Centers (4)
United States (206) · Canada (72) · Germany (72) · France (55) · Spain (55) · Poland (45) · Netherlands (41) · Australia (34) · Greece (31) · Italy (29) · Belgium (25) · Bulgaria (25) · China (24) · Czechia (24) · Denmark (24)
Hadar Lev-Tov, MD (5) · Christopher J Sayed, MD (3) · John W Frew, MD (3) · Lynne M Deans, MT (3) · Patricia Krantz (3) · Steven R Cohen, MD, MPH (3)
PMID 27518661, PMID 29380251, PMID 31111409, PMID 31604104, PMID 36746171, PMID 41248770, PMID 42482599, PMID 42525209, PMID 22236226, PMID 23247938, PMID 26114588, PMID 30378087, PMID 32147881, PMID 32460374, PMID 33433785, PMID 34252397, PMID 34978076, PMID 38795716, PMID 39101698, PMID 39141589, PMID 39425517, PMID 40153232, PMID 40172122, PMID 40372667, PMID 40652434, PMID 40839197, PMID 41107641, PMID 41689425, PMID 42247110, PMID 42493571, PMID 12140476, PMID 13845515, PMID 14632813, PMID 14759407, PMID 15280848, PMID 16918566, PMID 17587838, PMID 18557587, PMID 19036028, PMID 19185954, PMID 19233423, PMID 19293006, PMID 19438670, PMID 19797095, PMID 20039918, PMID 20115947, PMID 20166154, PMID 20227579, PMID 20479297, PMID 20626389
2023 (9), 2025 (9), 2018 (5), 2015 (4), 2019 (3), 2004 (1), 2008 (1), 2014 (1), 2017 (1), K08AR080844 (1), KL2RR031974 (1), R01NR013888 (1), R33AR077495 (1), R61AR087105 (1), UL1RR031975 (1)