11 completed, 3 terminated, 2 unknown, 1 withdrawn. 4 Phase 3, 4 Phase 4, 3 Not applicable, 3 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 3, Terminated 1 |
| Phase 4 | 4 | Completed 1, Terminated 1, Unknown 1, Withdrawn 1 |
| Not applicable | 3 | Completed 3 |
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Floxacillin: new trials by email Literature Review of Floxacillin trials Research Report on Floxacillin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Flucloxacillin as an Inducer of CYP-enzymes Flucloxacillin - Healthy Volunteers, Drug Drug Interaction | Phase 1 | Completed | University of Southern Denmark | 14 | 2021-03-25 | 2022-01-11 |
| Gentamicin in Cardiac Surgery Flucloxacillin and gentamicin, Flucloxacillin and ceftriaxone - Cardiac Infection | Not applicable | Completed | Al-Rasheed University College | 50 | 2020-01-01 | 2024-06-12 |
| Penicillin Against Flucloxacillin Treatment Evaluation Benzylpenicillin, Flucloxacillin - Staphylococcus Aureus | Phase 4 | Withdrawn | The University of Queensland | 2019-07-01 | 2022-11-16 | |
| Pharmacokinetics of Flucloxacillin Given by Continuous or Intermittent Infusion to ICU Patients Flucloxacillin - Bacterial Infections | Completed | Radboud University Medical Center | 30 | 2017-06-01 | 2018-10-23 | |
| Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA Dalbavancin, Vancomycin, Oxacillin - Methicillin-Resistant Staphylococcus Aureus, Bacterial Infections | Phase 3 | Completed | AbbVie | 199 | 2017-03-30 | 2024-09-19 |
| Penicillin for the Emergency Department Outpatient Treatment of CELLulitis Flucloxacillin, Phenoxymethylpenicillin, Placebo (for phenoxymethylpenicillin) - Cellulitis, Wound Infection | Phase 4 | Unknown | Royal College of Surgeons, Ireland | 414 | 2016-12-01 | 2016-10-04 |
| Target Attainment and Pharmacokinetics of Antimicrobials in Non-critically Ill Surgery Patients (TAPAS) amoxicillin-clavulanic acid - Surgery | Unknown | Universitaire Ziekenhuizen KU Leuven | 120 | 2016-11-30 | 2017-04-20 | |
| Combination Antibiotic Therapy for Methicillin Resistant Staphylococcus Aureus Infection Beta-Lactam - Methicillin-Resistant Staphylococcus Aureus | Phase 3 | Terminated | Menzies School of Health Research | 358 | 2015-08-26 | 2018-12-19 |
| Comparing the Intravenous Treatment of Skin Infections in Children, Home Versus Hospital Home, Ward, ceftriaxone - Cellulitis | Not applicable | Completed | Murdoch Childrens Research Institute | 190 | 2015-01-01 | 2022-11-08 |
| Duration of ANtibiotic Therapy for CEllulitis Flucloxacillin, Placebo (for flucloxacillin) - Cellulitis, Erysipelas | Phase 4 | Terminated | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 151 | 2014-08-26 | 2017-10-10 |
| Staphylococcus Aureus Bacteremia Antibiotic Treatment Options Trimethoprim-Sulfamethoxazole, Clindamycin, Linezolid - Staphylococcus Aureus Infection | Phase 3 | Completed | Heinrich-Heine University, Duesseldorf | 215 | 2013-12-01 | 2020-05-27 |
| Adjunctive Clindamycin for Cellulitis: C4C Trial. Flucloxacillin, Clindamycin, Placebo oral capsule - Cellulitis | Phase 4 | Completed | University Hospitals Bristol and Weston NHS Foundation Trust | 410 | 2013-10-01 | 2022-08-17 |
| Study to Compare Efficacy and Safety of Daptomycin in Elderly Patients With Complicated Skin and Soft Tissue Infections Daptomycin, Vancomycin or Semi-Synthetic Penicillins (SSPs) - Infections | Phase 3 | Completed | Novartis Pharmaceuticals | 120 | 2010-03-01 | 2012-07-13 |
| Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci daptomycin, vancomycin, teicoplanin - Osteomyelitis | Phase 2 | Completed | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 75 | 2007-06-26 | 2018-01-31 |
| The Effect of Antimicrobial Therapy on the Serum Level of P-cresol in Peritoneal Dialysis Patients Flucloxacillin - Chronic Kidney Disease | Phase 1 | Terminated | Universitaire Ziekenhuizen KU Leuven | 9 | 2006-03-01 | 2020-04-27 |
| Bioavailability Of Flucloxacillin Capsules (250 mg and 500 mg) flucloxacillin 250 mg, flucloxacillin 500 mg - Infections, Bacterial | Phase 1 | Completed | GlaxoSmithKline | 24 | 2005-01-06 | 2017-09-29 |
| Study of Acupuncture and Care Interventions for the Treatment of Breast Inflammation During Breastfeeding Acupuncture treatment, Administration of oxytocin nasal spray, Improved breast milk removal - Mastitis | Not applicable | Completed | Karlstad University | 210 | 2002-01-01 | 2006-12-04 |
Cellulitis (5) · Bacterial Infections (3) · Staphylococcal Infections (3) · Infections (2) · Abscess (1) · Breast Feeding (1) · Erysipelas (1) · Mastitis (1) · Osteomyelitis (1) · Renal Insufficiency, Chronic (1) · Sepsis (1) · Soft Tissue Infections (1) · Staphylococcal Skin Infections (1) · Wound Infection (1)
Universitaire Ziekenhuizen KU Leuven (2) · AbbVie (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Al-Rasheed University College (1) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · GlaxoSmithKline (1) · Heinrich-Heine University, Duesseldorf (1) · Karlstad University (1) · Menzies School of Health Research (1) · Murdoch Childrens Research Institute (1) · Novartis Pharmaceuticals (1) · Radboud University Medical Center (1) · Royal College of Surgeons, Ireland (1) · The University of Queensland (1) · University Hospitals Bristol and Weston NHS Foundation Trust (1)
Australia (3) · Germany (3) · Netherlands (3) · Russia (3) · Spain (3) · United Kingdom (3) · Belgium (2) · United States (2) · Argentina (1) · Austria (1) · Belarus (1) · Brazil (1) · Bulgaria (1) · Chile (1) · Colombia (1)
Abel Wakai, MD FRCEM (1) · Achim J Kaasch, MD (1) · Adrian Moughty (1) · Alistair Wheeler, MD (1) · Bodil Wilde Larsson, PhD (1) · Chris Luke (1) · Conor Deasy (1) · David Paterson (1) · Jan M. Prins, MD, PhD (1) · Joseph McKeever (1) · Joshua Davis, MBBS, FRACP (1) · Laila F Ibrahim, MBBChBAO (1)
PMID 22908174, PMID 23837413, PMID 24885384, PMID 26452342, PMID 26754176, PMID 27029920, PMID 28314743, PMID 28836993, PMID 30321312, PMID 30853250, PMID 31420292, PMID 32044943, PMID 32051007, PMID 33859725, PMID 38244557
2009 (1), 2014 (1)