16 completed, 5 unknown, 2 enrolling by invitation, 2 not yet recruiting. 28 Phase 2, 11 Phase 1, 4 Phase 3.
Follow Stomatognathic System Abnormalities: new trials by email Literature Review of Stomatognathic System Abnormalities trials Research Report on Stomatognathic System Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cleft Lip Scarring After Botox Botulinum Toxin Type A (BOTOX) Injection, Normal Saline - Cleft Lip, Cleft Lip Scar | Phase 2 | Recruiting | Children's National Research Institute | 40 | 2026-02-19 | 2026-10-19 |
| Efficacy and Safety of Allogenic Cultured Adipose-derived Mesenchymal Stromal Cell Injections on MoUth Fibrosis and Handicap in Patients With Systemic sclEroderma AdMSC, Placebo - Systemic Scleroderma | Phase 2 | Not yet recruiting | University Hospital, Toulouse | 50 | 2026-01-01 | 2026-01-08 |
| Hydroxyapatite vs Fluoride Toothpaste for MIH Remineralization non fluoridated hydroxyapatite tooth paste (KAREX KINDER tooth paste), fluoridated toothpaste (Colgate Total PROTECTION ACTIVE) - Molar Incisor Hypomineralisation | Phase 2 | Not yet recruiting | Dubai Health | 160 | 2025-11-01 | 2025-09-16 |
| Evaluation of a Novel Nasal Conformer in Pediatric Patients use of an anatomically designed nasal conformer - Cleft Lip, Nasal Surgical Procedures | Phase 2 | Enrolling by invitation | East Tennessee Children's Hospital | 20 | 2025-06-01 | 2026-09-16 |
| Evaluating the Accuracy of Soft Tissue Prediction in Patients With Mandibular Prognathism After Orthognathic Surgery Using Handheld Scanner Versus Optical Scanner A Prospective Clinical Trial face scanning pre and post orthognathic surgery - Mandibular Prognathism, Orthognathic Surgery | Phase 1 / Phase 2 | Enrolling by invitation | Cairo University | 11 | 2024-09-24 | 2024-12-09 |
| Phase I-IIa, to Evaluate the Safety, Feasibility, and Efficacy of the Use of BIOCLEFT in the Treatment of Cleft Palate. implantation with an autologous human palatal mucosa substitute made of nanostructured fibrin-agarose generated by tissue engineering (BIOCLEFT). - Cleft Lip and Palate | Phase 1 / Phase 2 | Recruiting | Elisa María Cubiles Montero de Espinosa | 15 | 2024-04-17 | 2024-05-10 |
| The Desensitising Effect of Nanosilver Fluoride in Molar-Incisor Hypomineralisation Low-level laser therapy, Nanosilver fluoride - Molar Incisor Hypomineralization, Hypersensitivity | Phase 2 / Phase 3 | Completed | Alexandria University | 120 | 2024-04-01 | 2025-01-30 |
| Augmented Reality for Orthognatic Surgery Patient Education Patient consultation - Malocclusion, Dentofacial Deformities | Phase 2 / Phase 3 | Completed | University Medical Center Groningen | 60 | 2023-10-01 | 2025-03-30 |
| Evaluation of Antimicrobial Photodynamic Therapy and Minimal Intervention Associated With Deproteinization in Permanent Teeth With Molar Incisor Hypomineralization Antimicrobial PDT and Papacarie Deproteinization, Conventional caries treatment, Antimicrobial PDT and 5% NaOCl Deproteinization - Hypomineralization Molar Incisor | Phase 1 / Phase 2 | Unknown | University of Nove de Julho | 69 | 2023-08-20 | 2023-11-28 |
| Articaine 4% Versus Lidocaine 2% for Local Anesthesia of MIH-affected Maxillary Molars Lidocaine 2%, Articaine 4% - Molar Incisor Hypomineralisation | Phase 1 / Phase 2 | Completed | Latakia University | 26 | 2022-10-17 | 2023-05-03 |
| Pharmacological Treatment on the Recovery of Neurosensory Disturbance After Bilateral Sagittal Split Osteotomy Orthognathic Surgery, Melatonin 10 MG Oral Tablet, Hydroxycobalamin - Retrognathism, Prognathism | Phase 2 / Phase 3 | Unknown | Universitat Internacional de Catalunya | 220 | 2022-09-30 | 2022-09-13 |
| Photobiomodulation and Glass Ionomer Sealant as Complementary Treatment for Hypersensitivity in Molars With MIH Use of fluoride toothpaste, Photobiomodulation, Simulated Laser Therapy - Hypomineralization Molar Incisor | Phase 1 / Phase 2 | Completed | University of Nove de Julho | 50 | 2022-07-19 | 2024-10-03 |
| Local Anesthesia With Lidocaine or Articaine for Molars Affected by MIH Lidocaine 2%, Articaine 4% - Molar Incisor Hypomineralisation | Phase 1 / Phase 2 | Completed | Latakia University | 20 | 2022-01-22 | 2022-07-15 |
| Control of Pain Due to Dentin Hypersensitivity in Individuals With Molar-incisor Hypomineralization Hygiene Instructions, Sealant application, Low-level Laser - Dentin Sensitivity, Molar Incisor Hypomineralization | Phase 1 / Phase 2 | Unknown | University of Nove de Julho | 140 | 2021-01-01 | 2020-11-30 |
| Dexmedetomidine Versus Sevoflurane in Children With Anticipated Difficult Intubation dexmedetomidine, sevoflurane - Craniofacial Abnormalities, Mandibular Hypoplasia | Phase 2 | Unknown | Alexandria University | 40 | 2020-06-01 | 2020-06-12 |
| Suprazygomatic Block in Cleft Palate Surgery in Children Bupivacaine, Dexmedetomidine, paracetamol - Cleft Palate | Phase 2 | Completed | Assiut University | 80 | 2018-01-14 | 2018-09-24 |
| Does it Worth to Reinforce With Additional Anesthesia to Improve Postoperative Course After Orthognathic Surgery? Second infiltration pre-extubation with ropivacaine - Dentofacial Deformities | Phase 2 | Completed | Servei Central d'Anestesiologia | 52 | 2018-01-10 | 2020-02-13 |
| Effects of Oral Melatonin on Neurosensory Recovery Following Facial Osteotomies Oral Melatonin 10mg, Placebo - Dentofacial Deformities | Phase 2 | Unknown | The University of Hong Kong | 40 | 2016-06-01 | 2016-09-07 |
| Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate Surgery Levobupivacaine, Bupivacaine - Recovery After Cleft Palate Surgery | Phase 2 / Phase 3 | Completed | Assiut University | 60 | 2016-01-01 | 2017-09-07 |
| IV Acetaminophen in Children Undergoing Palatoplasty IV acetaminophen, Placebo - Cleft Palate | Phase 2 | Withdrawn | Nationwide Children's Hospital | 2015-12-01 | 2016-03-08 |
Showing 20 of 28. Sign in to see all of them.
Cleft Palate (9) · Cleft Lip (7) · Molar Hypomineralization (7) · Dentofacial Deformities (3) · Retrognathia (3) · Micrognathism (2) · Prognathism (2) · Alveolar Bone Loss (1) · Cicatrix (1) · Craniofacial Abnormalities (1) · Dentin Sensitivity (1) · Hypersensitivity (1) · Malocclusion (1) · Malocclusion, Angle Class III (1) · Microstomia (1)
Congenital Abnormalities (28) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (28) · Stomatognathic Diseases (28) · Maxillofacial Abnormalities (17) · Musculoskeletal Abnormalities (17) · Musculoskeletal Diseases (17) · Craniofacial Abnormalities (16) · Jaw Abnormalities (14) · Jaw Diseases (14) · Mouth Abnormalities (14) · Mouth Diseases (14) · Tooth Diseases (9) · Dental Enamel Hypomineralization (7) · Developmental Defects of Enamel (7)
Low-Level Light Therapy (3) · Saline Solution (3) · Acetaminophen (2) · Botulinum Toxins, Type A (2) · Bupivacaine (2) · Dexmedetomidine (2) · Melatonin (2) · Orthognathic Surgery (2) · Ampicillin (1) · Cytidine (1) · Drug Implants (1) · Hydroxocobalamin (1) · Levobupivacaine (1) · Osteogenesis, Distraction (1) · Ropivacaine (1)
University of Nove de Julho (3) · Alexandria University (2) · Assiut University (2) · Latakia University (2) · The University of Hong Kong (2) · Cairo University (1) · Children's National Research Institute (1) · Dubai Health (1) · East Tennessee Children's Hospital (1) · Elisa María Cubiles Montero de Espinosa (1) · Hospital Sirio-Libanes (1) · Joseph Losee (1) · Nationwide Children's Hospital (1) · Servei Central d'Anestesiologia (1) · Shiraz University of Medical Sciences (1)
United States (7) · Egypt (5) · Brazil (4) · Hong Kong (2) · Spain (2) · Syria (2) · France (1) · Germany (1) · Iran (1) · Netherlands (1)
Mai Haidar, Dr (2) · Nabih Raslan, Dr (2) · Crystal TY Lee, BDS (HKU) (1) · Daniela Francescato Veiga (1) · Darnell Kaigler, DDS, PhD (1) · J Kraeima, dr. (1) · Jaecel O Shah, MD (1) · Joseph Losee, MD (1) · Lim K Cheung, BDS, PhD (1) · Miriam DeNadal, MD, PhD (1) · Mohamed Ahmed Farid, Professor of OMFS (1) · Negin Matini, DMD (1) · Pedro Sole, DMD, OMFS (1)
PMID 20443823, PMID 21120277, PMID 23117614, PMID 33692185, PMID 37316315, PMID 37526883, PMID 38101830, PMID 39638596, PMID 40716831, PMID 40883469, PMID 42069961
R01DE010437 (1)