106 completed, 48 unknown, 26 recruiting, 12 not yet recruiting. 121 Not applicable, 14 Phase 2, 11 Phase 3, 8 Phase 1, 6 Phase 4.
Follow Jaw Abnormalities: new trials by email Literature Review of Jaw Abnormalities trials Research Report on Jaw Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Furlow With Buccinator and Fistula Formation furlow with buccinator, two flap palatoplasty - Cleft Palate | Not applicable | Not yet recruiting | Fayoum University | 20 | 2026-09-25 | 2026-09-25 |
| Palatoplasty Techniques Using PRF and Gentamicin-Loaded PRF in Cleft Palate Standard palatoplasty ( control), Platelet _ Rich Fibrin ( PRF), gentamicin_ loaded PRF - Cleft Palate, Unilateral Cleft Palate | Not applicable | Recruiting | Al-Thawra Modern General Hospital | 90 | 2026-08-01 | 2026-08-07 |
| Speech Intervention Frameworks in Cantonese-speaking Children and Adolescences With Cleft Palate +/- Lip Non-linear based phonological speech intervention, Linear-based speech intervention - Cleft Palate +/- Lip | Not applicable | Enrolling by invitation | Chinese University of Hong Kong | 12 | 2026-07-24 | 2026-07-09 |
| Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring Standard General Anesthesia per Institutional Protocol - Cleft Palate, Cleft Lip | Not yet recruiting | Marmara University Pendik Training and Research Hospital | 150 | 2026-06-27 | 2026-06-16 | |
| MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair Modified Furlow Palatoplasty combined with buccinator myomucosal flap - Cleft Palate, Cleft Palate, Unilateral, Complete | Not applicable | Not yet recruiting | Cairo University | 10 | 2026-06-01 | 2026-04-07 |
| Using Chin Bone Rings for Sinus Lifting and Dental Implants in One Surgery Bone Ring Technique (BRT) - Maxillary Deficiency, Bone Resorption | Not applicable | Recruiting | Damascus University | 10 | 2026-05-31 | 2026-09-01 |
| Evaluation of Emotional Responses Using the I-Motions System and Self-assessment Questionnaires, and Assessment of Postoperative Anatomical and Structural Units (TMJ and Masticatory Muscles) in Orthognathic Surgery Patients Observational Assessment - Orthognathic Surgery, Malocclusions | Not applicable | Enrolling by invitation | Lithuanian University of Health Sciences | 100 | 2026-03-03 | 2026-03-17 |
| Speech Intervention Via Telepractice for Children With Repaired Cleft Palate Speech therapy via teleprace, Face-to-face speech therapy - Cleft Palate Children, Speech Sound Disorder | Not applicable | Not yet recruiting | Texas Tech University Health Sciences Center | 64 | 2026-03-02 | 2026-02-27 |
| Effects of AlignBabyCleft (ABaCleft) Appliance. Orthodontic appliance to carry out dentoalveolar movement - Cleft Lip, Cleft Palate | Not applicable | Not yet recruiting | Universidad Complutense de Madrid | 30 | 2025-11-21 | 2025-04-25 |
| Early Intervention in Infants With Unrepaired Cleft Palate: Language, Palatal Function, and Articulation. Early intervention for language, articulation and palatal function skills - Cleft Lip and Cleft Palate, Cleft Lip Palate | Not applicable | Not yet recruiting | Old Dominion University | 200 | 2025-10-21 | 2025-10-22 |
| Leaf Expander Versus Hyrax Expander in Mixed Dentition Patients With Posterior Crossbite. The Leaf expander, Hyrax expander - Posterior Crossbite, Maxilla; Hypoplasia | Not applicable | Recruiting | Cairo University | 30 | 2025-10-01 | 2026-06-04 |
| Associations Between Radiographic Inclination of Premolars and Maxillary Expansion Rapid palatal expansion - Maxillary Deficiency | Enrolling by invitation | University of Pavia | 200 | 2025-09-01 | 2025-11-18 | |
| Trial to Compare the Effects of Myo Munchee Therapy and Oral Motor Therapy (OMT) in Pediatric Patients to Treat Maxillary Deficiency and Orofacial Myofunctional Dysfunction (OMD). Chewing device only, Myo Munchee and Oral Motor Therapy Treatment, Oral Motor Therapy Treatment Arm - Orofacial Myofunctional Disorders, Myo Munchee | Not applicable | Recruiting | Myo Munchee (Operations) Pty Ltd | 48 | 2025-08-20 | 2025-07-28 |
| Predictors of Patient-Reported Outcomes for Maxillectomy Patients Digitally Fabricated Obturator Prosthesis - Maxillary Deficiency, Head and Neck Neoplasms | Not applicable | Completed | Dr. Merve Benli | 75 | 2025-08-12 | 2026-10-08 |
| Aesthetic and Functional Self-Assessment Following Rhinoseptoplasty in Patients With Unilateral Cleft Lip and Palate Mailing and completing CLEFT-Q and NOSE questionnaires - Cleft Lip and Cleft Palate | Recruiting | University Hospital, Montpellier | 80 | 2025-07-09 | 2025-07-22 | |
| Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery Methadone hydrochloride, Fentanyl/Hydromorphone - Cleft Palate, Pain | Phase 4 | Recruiting | Duke University | 60 | 2025-06-04 | 2026-04-14 |
| Incidence of Body Dysmorphic Disorder (BDD) in a Population of Patients Undergoing Orthognathic Surgery Questionnaire and Physical Exam - Orthognathic Surgical Procedures, Psychiatric Disorders | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 90 | 2025-05-01 | 2025-03-17 | |
| The Effect of Mandibular Advancement With Clear Aligners on Maxillary and Mandibular Volumes Mandibular Advancement Appliance (Invisalign MA), Activator Appliance - Mandibular Retrognathia | Not applicable | Completed | Batman University | 55 | 2025-05-01 | 2025-07-09 |
| Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II MARA appliance, fixed twin block - Class II Malocclusion, Mandibular Deficiency | Not applicable | Recruiting | Mansoura University | 60 | 2025-04-27 | 2026-01-14 |
| Evaluation of Maxillary Expansion Using Clear Aligners' Therapy in Patients With Cleft Lip and Palate at the Mixed Dentition Stage clear aligners - Maxillary Deficiency, Cleft Lip and Palate | Not applicable | Recruiting | Cairo University | 10 | 2025-04-06 | 2025-06-12 |
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Cleft Palate (114) · Retrognathia (58) · Cleft Lip (46) · Micrognathism (26) · Pierre Robin Syndrome (16) · Malocclusion (10) · Prognathism (10) · Malocclusion, Angle Class III (9) · Congenital Abnormalities (6) · Velopharyngeal Insufficiency (6) · Craniofacial Abnormalities (5) · Dentofacial Deformities (4) · Malocclusion, Angle Class II (4) · Pain, Postoperative (4)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (214) · Jaw Diseases (213) · Musculoskeletal Abnormalities (213) · Musculoskeletal Diseases (213) · Stomatognathic Diseases (213) · Stomatognathic System Abnormalities (213) · Maxillofacial Abnormalities (211) · Craniofacial Abnormalities (209) · Congenital Abnormalities (208) · Mouth Diseases (118) · Mouth Abnormalities (114) · Mandibular Diseases (64) · Lip Diseases (46) · Pathological Conditions, Signs and Symptoms (33)
Saline Solution (6) · Bupivacaine (5) · Orthognathic Surgery (5) · Dexmedetomidine (4) · Acetaminophen (3) · Masks (3) · Activator Appliances (2) · Enteral Nutrition (2) · Fentanyl (2) · Folic Acid (2) · Levobupivacaine (2) · Nasoalveolar Molding (2) · Osteogenesis, Distraction (2) · Sodium Chloride (2) · Surveys and Questionnaires (2)
Cairo University (16) · Assiut University (8) · Fayoum University (7) · Al-Azhar University (5) · AZ Sint-Jan AV (4) · Damascus University (4) · University Hospital, Basel, Switzerland (4) · University Hospital, Montpellier (4) · Ain Shams University (3) · Alexandria University (3) · Ankara University (3) · Hospices Civils de Lyon (3) · Mansoura University (3) · Tanta University (3) · The Hospital for Sick Children (3)
Egypt (45) · United States (35) · France (15) · Turkey (Türkiye) (12) · Belgium (10) · Brazil (10) · Canada (9) · China (5) · Italy (5) · Switzerland (5) · Iran (4) · Norway (4) · Sweden (4) · Syria (4) · Denmark (3)
Cuneyt M Alper, MD (2) · Fabianne MG Furtado, PhD (2) · Gabriela PR Prado, MS (2) · Jeff Murray, M.D. (2) · Johan Abeloos, MD (2) · Lydia M Ferreira, PhD (2) · Nieto Luis, Master (2) · Abdulmalek Majanni, DDS MSc (1) · Ahamd Burhan, DDS MSc PhD (1) · Ahmad S. Zakaria, DDS MSc (1) · Ahmed Barakat, Professor (1) · Alessandro Moro, MD (1) · Alessandro Ugolini (1) · Alexander C Allori, MD, MPH (1)
PMID 10371309, PMID 10883694, PMID 14707617, PMID 1472517, PMID 16122596, PMID 16448254, PMID 16563165, PMID 18452361, PMID 18980518, PMID 19761925, PMID 19854614, PMID 20347265, PMID 20443823, PMID 21091369, PMID 21120277, PMID 21740160, PMID 21823827, PMID 22204448, PMID 22230559, PMID 22682069, PMID 23117614, PMID 23181832, PMID 23382797, PMID 23643382, PMID 23669628, PMID 23690355, PMID 24525630, PMID 25394172, PMID 26847514, PMID 27053961, PMID 27129491, PMID 27258654, PMID 27533493, PMID 28018773, PMID 28274235, PMID 28279603, PMID 28921849, PMID 31300507, PMID 31795731, PMID 32049908, PMID 32081579, PMID 32423402, PMID 33107321, PMID 33397459, PMID 33827851, PMID 34465477, PMID 34896005, PMID 35100923, PMID 35874558, PMID 36721240
R21DC017553 (2), 2014 (1), 2015 (1), P50DC007667 (1), R01DC011524 (1), R01DE010437 (1), R01HL105241 (1), R21HL087819 (1), U01DE017958 (1), U01DE018837 (1), U01DE020057 (1), U01HD040561 (1)